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The map label for this gene is yrbE [H]

Identifier: 45656420

GI number: 45656420

Start: 629186

End: 630154

Strand: Reverse

Name: yrbE [H]

Synonym: LIC10522

Alternate gene names: 45656420

Gene position: 630154-629186 (Counterclockwise)

Preceding gene: 45656421

Following gene: 45656419

Centisome position: 14.73

GC content: 37.15

Gene sequence:

>969_bases
ATGACAGAAAGAGTTAAACTCGGCGTGATCGGAACCGGTCATATGGGCCAGTATCACGTAAACGTTGCCAAAACCCTTAA
CGACGCAACCCTAGTTGGAATTTACGACTCGGATTTAGAAAGAGCAAAACAAATCGCAGAAAAACATAAAACTCTAGCAT
TCTCTACAATCGACGAATTAATTTCAAAAACAGATGCGGTTGTAATTGCAGTTCCTACTTTTTTGCATCATGAAATTGCC
AAAAAAGCATTAGAAGCCAACAAACACGTATTAGTCGAAAAACCTATTGCTGAAACTACCAATCAAGCCAAGGAACTCGT
AAAAATCGCTGGGGAAAAAAATTTAGTTCTTCTTGTAGGCCACGTGGAAAGATTTAACGGAGCAGTATTAGAATTAAGTA
AAATTGTAAAAGATCCTTTGTTGATAGAATCTAGAAGACTAGCTCCCTCTAATTCTAGAATTAAAGACGTCGGAGTTGTC
CTAGATATGATGATTCACGATATTGATATTGTGCTGAACCTGGTAAATTCTCCCGTTAAAAAACTCTCTGCCTCAGGTAA
AAAGGTATCATCCGATCACGAAGACGTTGCAAATGTGTTACTCGAATTTGAAAACGGATGCCTAGCAAGTATTACTGCGT
CCAGAGCAACTCAAGCAAAAATTAGAACCTTGAATATCACTCAGAAAGACGTCTATATCATGCTCGATTTTACGGATCAA
GAAATAGAACTACATAGACAAGCCACTTCGGACATTCTTCTTTTATCCGAAGAGATCAAATATCGCCAGGAATCAATCGT
GGAAAAAATATTCGTTCATAAAGACAATCCTCTCAAACAAGAACACGAACATTTTATCCGTTGTATCAGAAAAGAAATAG
AACCGATCGTGAATAGAAATTCGGACGTTTCTACTTTAGAAATTGCTTATCAAATTCTTTCGGAAATTCACGGAACTTCT
AATAAGTAA

Upstream 100 bases:

>100_bases
AATTACCAAACTGTAAAATTTTTAGGACAAACCTTGGTAAAAATTCGAGAAACCATTTTTCGAAAAACACAACCTGATCG
CAGAACTAAAAGGAAATACA

Downstream 100 bases:

>100_bases
TCCAGTCTAAAATTGGTTAAAATATGGAAGAAAATTACAGCGGAAAAATTTTAATCTCCAATTCTTCGATCGTCATGGAT
TATTTTAATCGAACCGTCAT

Product: oxidoreductase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MTERVKLGVIGTGHMGQYHVNVAKTLNDATLVGIYDSDLERAKQIAEKHKTLAFSTIDELISKTDAVVIAVPTFLHHEIA
KKALEANKHVLVEKPIAETTNQAKELVKIAGEKNLVLLVGHVERFNGAVLELSKIVKDPLLIESRRLAPSNSRIKDVGVV
LDMMIHDIDIVLNLVNSPVKKLSASGKKVSSDHEDVANVLLEFENGCLASITASRATQAKIRTLNITQKDVYIMLDFTDQ
EIELHRQATSDILLLSEEIKYRQESIVEKIFVHKDNPLKQEHEHFIRCIRKEIEPIVNRNSDVSTLEIAYQILSEIHGTS
NK

Sequences:

>Translated_322_residues
MTERVKLGVIGTGHMGQYHVNVAKTLNDATLVGIYDSDLERAKQIAEKHKTLAFSTIDELISKTDAVVIAVPTFLHHEIA
KKALEANKHVLVEKPIAETTNQAKELVKIAGEKNLVLLVGHVERFNGAVLELSKIVKDPLLIESRRLAPSNSRIKDVGVV
LDMMIHDIDIVLNLVNSPVKKLSASGKKVSSDHEDVANVLLEFENGCLASITASRATQAKIRTLNITQKDVYIMLDFTDQ
EIELHRQATSDILLLSEEIKYRQESIVEKIFVHKDNPLKQEHEHFIRCIRKEIEPIVNRNSDVSTLEIAYQILSEIHGTS
NK
>Mature_321_residues
TERVKLGVIGTGHMGQYHVNVAKTLNDATLVGIYDSDLERAKQIAEKHKTLAFSTIDELISKTDAVVIAVPTFLHHEIAK
KALEANKHVLVEKPIAETTNQAKELVKIAGEKNLVLLVGHVERFNGAVLELSKIVKDPLLIESRRLAPSNSRIKDVGVVL
DMMIHDIDIVLNLVNSPVKKLSASGKKVSSDHEDVANVLLEFENGCLASITASRATQAKIRTLNITQKDVYIMLDFTDQE
IELHRQATSDILLLSEEIKYRQESIVEKIFVHKDNPLKQEHEHFIRCIRKEIEPIVNRNSDVSTLEIAYQILSEIHGTSN
K

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=278, Percent_Identity=24.1007194244604, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787307, Length=316, Percent_Identity=25.9493670886076, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787574, Length=197, Percent_Identity=29.9492385786802, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1789848, Length=136, Percent_Identity=31.6176470588235, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87081947, Length=195, Percent_Identity=27.6923076923077, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36037; Mature: 35906

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERVKLGVIGTGHMGQYHVNVAKTLNDATLVGIYDSDLERAKQIAEKHKTLAFSTIDEL
CCCEEEEEEEECCCCCEEEEEHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
ISKTDAVVIAVPTFLHHEIAKKALEANKHVLVEKPIAETTNQAKELVKIAGEKNLVLLVG
HHCCCEEEEEEHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCCEEEEEE
HVERFNGAVLELSKIVKDPLLIESRRLAPSNSRIKDVGVVLDMMIHDIDIVLNLVNSPVK
CHHHHCCHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLSASGKKVSSDHEDVANVLLEFENGCLASITASRATQAKIRTLNITQKDVYIMLDFTDQ
HHHCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHEEEEEEECCCEEEEEECCCH
EIELHRQATSDILLLSEEIKYRQESIVEKIFVHKDNPLKQEHEHFIRCIRKEIEPIVNRN
HHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
SDVSTLEIAYQILSEIHGTSNK
CCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TERVKLGVIGTGHMGQYHVNVAKTLNDATLVGIYDSDLERAKQIAEKHKTLAFSTIDEL
CCEEEEEEEECCCCCEEEEEHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
ISKTDAVVIAVPTFLHHEIAKKALEANKHVLVEKPIAETTNQAKELVKIAGEKNLVLLVG
HHCCCEEEEEEHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCCEEEEEE
HVERFNGAVLELSKIVKDPLLIESRRLAPSNSRIKDVGVVLDMMIHDIDIVLNLVNSPVK
CHHHHCCHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLSASGKKVSSDHEDVANVLLEFENGCLASITASRATQAKIRTLNITQKDVYIMLDFTDQ
HHHCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHEEEEEEECCCEEEEEECCCH
EIELHRQATSDILLLSEEIKYRQESIVEKIFVHKDNPLKQEHEHFIRCIRKEIEPIVNRN
HHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
SDVSTLEIAYQILSEIHGTSNK
CCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]