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The map label for this gene is fadE9

Identifier: 41410312

GI number: 41410312

Start: 4683748

End: 4684908

Strand: Reverse

Name: fadE9

Synonym: MAP4214c

Alternate gene names: 41410312

Gene position: 4684908-4683748 (Counterclockwise)

Preceding gene: 41410313

Following gene: 41410311

Centisome position: 97.0

GC content: 70.28

Gene sequence:

>1161_bases
ATGTTTACCCTGGACGACGACGAGCGGGTGATCGCCGAGACGGCCGCCGCGTTCGCCGCCAAGCGCCTGGCCCCGCACGC
GCTGGAATGGGATGCGGCCGAACACTTTCCGGTTGACGTGCTGCGCGAGTCGGCCGAGCTCGGGATGGCGGCGATCTACT
GCCGCGAGGACGTCGGCGGCAGCGGGCTGCGCCGGCTGGACGGGGTCCGCATCTTCGAGCAGCTGGCCATCGCCGACCCC
ACCACGGCCGCGTTCCTGTCCATCCACAACATGTGCGCGTGGATGATCGACAGCTACGGCACGCCCGAACAGCGCAAGGC
CTGGGTGCCGCGGCTGGCGGCGATGGACGTCATCGCCAGCTACTGCCTGACCGAGCCGGGCGCGGGGTCCGACGCCGCCG
CGCTGAGCACCCGCGCGGTCAGACAGGGCGGCGATTACGTGCTGGACGGCGTCAAGCAGTTCATCTCGGGCGCCGGGGCC
TCCGACGTCTACCTGGTGATGGCCCGCACGGGCGGTGAAGGGCCGCGCGGCATCTCCGCGTTCGTCGTCGAAAAGGGTTC
TGCTGGGCTGAGTTTCGGTTCGCCCGAGGAGAAGATGGGCTGGCACGCCCAACCCACCGCGCAGGTGATCCTGGAGGGGG
TGCGGGTGCCCGCCGACGCGATGCTGGGCGGCGCCGAGGGTGAGGGCGCCGGATTCGGCATCGCGATGAACGGCCTCAAC
GGCGGCCGGCTCAACATCGCCGCGTGCTCGCTGGGCGGCGCGCAGGCGGCCTTCGACAAGGCCGGGGCCTACGTGCGCGA
TCGGCAGGCGTTCGGGTCGCCGCTGCTCGACGAGCCGACCATCCGGTTCGCCCTGGCCGACATGGCCACCGGCCTGGAAA
CGTCGCGAATGATGTTGTGGCGGGCCGCCGGTGCGCTGGACGCCGACGATCCCGACAAGGTCGAGTTGTGCGCGATGGCC
AAACGCTACGTCACCGACACCTGCTTCGAGGTCGCCGACAAGGCGCTGCAGCTGCACGGCGGCTACGGCTATCTGCGCGA
GTATGGTCTGGAGAAGATCGTGCGCGACCTGCGGGTGCATCGCATCCTGGAGGGGACCAACGAGATCATGCGGGTGGTCA
TCGGCCGGGCCGAAGCGGCGCGGTTCCGGGCCACCGCATAG

Upstream 100 bases:

>100_bases
TCAAGACCGTCACGTCGCGGTGGCCGTCCGGCATCAAGGACGGCGCCGAATTCGTGATTCCCACAATGGATTAGAACCGA
GAAGGAATTCCGGCCCCACT

Downstream 100 bases:

>100_bases
AAAGGCCGTCGGATGACCGAGCGCGTGGTGGTGGCTTTCCTGGGCCTGGGCAACATGGGCGCGCCGATGGCGGCGAATCT
CGTTGCGGCCCAACATGCGG

Product: FadE9

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MFTLDDDERVIAETAAAFAAKRLAPHALEWDAAEHFPVDVLRESAELGMAAIYCREDVGGSGLRRLDGVRIFEQLAIADP
TTAAFLSIHNMCAWMIDSYGTPEQRKAWVPRLAAMDVIASYCLTEPGAGSDAAALSTRAVRQGGDYVLDGVKQFISGAGA
SDVYLVMARTGGEGPRGISAFVVEKGSAGLSFGSPEEKMGWHAQPTAQVILEGVRVPADAMLGGAEGEGAGFGIAMNGLN
GGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGSPLLDEPTIRFALADMATGLETSRMMLWRAAGALDADDPDKVELCAMA
KRYVTDTCFEVADKALQLHGGYGYLREYGLEKIVRDLRVHRILEGTNEIMRVVIGRAEAARFRATA

Sequences:

>Translated_386_residues
MFTLDDDERVIAETAAAFAAKRLAPHALEWDAAEHFPVDVLRESAELGMAAIYCREDVGGSGLRRLDGVRIFEQLAIADP
TTAAFLSIHNMCAWMIDSYGTPEQRKAWVPRLAAMDVIASYCLTEPGAGSDAAALSTRAVRQGGDYVLDGVKQFISGAGA
SDVYLVMARTGGEGPRGISAFVVEKGSAGLSFGSPEEKMGWHAQPTAQVILEGVRVPADAMLGGAEGEGAGFGIAMNGLN
GGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGSPLLDEPTIRFALADMATGLETSRMMLWRAAGALDADDPDKVELCAMA
KRYVTDTCFEVADKALQLHGGYGYLREYGLEKIVRDLRVHRILEGTNEIMRVVIGRAEAARFRATA
>Mature_386_residues
MFTLDDDERVIAETAAAFAAKRLAPHALEWDAAEHFPVDVLRESAELGMAAIYCREDVGGSGLRRLDGVRIFEQLAIADP
TTAAFLSIHNMCAWMIDSYGTPEQRKAWVPRLAAMDVIASYCLTEPGAGSDAAALSTRAVRQGGDYVLDGVKQFISGAGA
SDVYLVMARTGGEGPRGISAFVVEKGSAGLSFGSPEEKMGWHAQPTAQVILEGVRVPADAMLGGAEGEGAGFGIAMNGLN
GGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGSPLLDEPTIRFALADMATGLETSRMMLWRAAGALDADDPDKVELCAMA
KRYVTDTCFEVADKALQLHGGYGYLREYGLEKIVRDLRVHRILEGTNEIMRVVIGRAEAARFRATA

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7656849, Length=374, Percent_Identity=53.7433155080214, Blast_Score=421, Evalue=1e-118,
Organism=Homo sapiens, GI4557233, Length=373, Percent_Identity=37.8016085790885, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI4501859, Length=382, Percent_Identity=34.5549738219895, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI4557231, Length=386, Percent_Identity=31.6062176165803, Blast_Score=220, Evalue=1e-57,
Organism=Homo sapiens, GI187960098, Length=386, Percent_Identity=31.6062176165803, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI4501857, Length=380, Percent_Identity=33.6842105263158, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI76496475, Length=358, Percent_Identity=33.7988826815642, Blast_Score=201, Evalue=7e-52,
Organism=Homo sapiens, GI4557235, Length=358, Percent_Identity=33.7988826815642, Blast_Score=201, Evalue=8e-52,
Organism=Homo sapiens, GI226958412, Length=386, Percent_Identity=31.3471502590674, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI21361497, Length=366, Percent_Identity=31.9672131147541, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI226958414, Length=346, Percent_Identity=31.5028901734104, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI4503943, Length=377, Percent_Identity=30.2387267904509, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI7669494, Length=348, Percent_Identity=30.4597701149425, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI48976061, Length=292, Percent_Identity=27.7397260273973, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI211971008, Length=292, Percent_Identity=27.7397260273973, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI38505218, Length=291, Percent_Identity=27.1477663230241, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI87081958, Length=347, Percent_Identity=32.8530259365994, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1786223, Length=386, Percent_Identity=26.4248704663212, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI87082384, Length=259, Percent_Identity=31.2741312741313, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17533517, Length=375, Percent_Identity=49.0666666666667, Blast_Score=379, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17534899, Length=394, Percent_Identity=36.0406091370558, Blast_Score=240, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17569725, Length=388, Percent_Identity=34.020618556701, Blast_Score=224, Evalue=6e-59,
Organism=Caenorhabditis elegans, GI17506239, Length=375, Percent_Identity=33.3333333333333, Blast_Score=208, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17508101, Length=375, Percent_Identity=32.5333333333333, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17570075, Length=384, Percent_Identity=31.7708333333333, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17538396, Length=385, Percent_Identity=32.2077922077922, Blast_Score=187, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI71985184, Length=355, Percent_Identity=32.3943661971831, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=38.3620689655172, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17505929, Length=382, Percent_Identity=29.3193717277487, Blast_Score=157, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI71990804, Length=266, Percent_Identity=33.8345864661654, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17551932, Length=384, Percent_Identity=28.6458333333333, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17534353, Length=378, Percent_Identity=29.8941798941799, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71982178, Length=276, Percent_Identity=31.1594202898551, Blast_Score=144, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI71985192, Length=285, Percent_Identity=31.2280701754386, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17562446, Length=336, Percent_Identity=26.7857142857143, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17531909, Length=250, Percent_Identity=28, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI86563383, Length=323, Percent_Identity=28.7925696594427, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI86563381, Length=323, Percent_Identity=28.7925696594427, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24666513, Length=375, Percent_Identity=34.6666666666667, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24660351, Length=390, Percent_Identity=34.6153846153846, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24646207, Length=375, Percent_Identity=37.6, Blast_Score=218, Evalue=5e-57,
Organism=Drosophila melanogaster, GI21356377, Length=373, Percent_Identity=34.0482573726542, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI281363737, Length=338, Percent_Identity=35.7988165680473, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI21355753, Length=389, Percent_Identity=33.4190231362468, Blast_Score=197, Evalue=9e-51,
Organism=Drosophila melanogaster, GI19920834, Length=383, Percent_Identity=27.154046997389, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41145; Mature: 41145

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTLDDDERVIAETAAAFAAKRLAPHALEWDAAEHFPVDVLRESAELGMAAIYCREDVGG
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCC
SGLRRLDGVRIFEQLAIADPTTAAFLSIHNMCAWMIDSYGTPEQRKAWVPRLAAMDVIAS
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
YCLTEPGAGSDAAALSTRAVRQGGDYVLDGVKQFISGAGASDVYLVMARTGGEGPRGISA
HHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCEE
FVVEKGSAGLSFGSPEEKMGWHAQPTAQVILEGVRVPADAMLGGAEGEGAGFGIAMNGLN
EEEECCCCCCCCCCCHHHCCCCCCCHHHHHHHHCCCCHHHHCCCCCCCCCCEEEEEECCC
GGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGSPLLDEPTIRFALADMATGLETSRMMLW
CCEEEEEEECCCCHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHH
RAAGALDADDPDKVELCAMAKRYVTDTCFEVADKALQLHGGYGYLREYGLEKIVRDLRVH
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RILEGTNEIMRVVIGRAEAARFRATA
HHHHHHHHHHHHHHCCHHHHHHCCCC
>Mature Secondary Structure
MFTLDDDERVIAETAAAFAAKRLAPHALEWDAAEHFPVDVLRESAELGMAAIYCREDVGG
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCC
SGLRRLDGVRIFEQLAIADPTTAAFLSIHNMCAWMIDSYGTPEQRKAWVPRLAAMDVIAS
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
YCLTEPGAGSDAAALSTRAVRQGGDYVLDGVKQFISGAGASDVYLVMARTGGEGPRGISA
HHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCEE
FVVEKGSAGLSFGSPEEKMGWHAQPTAQVILEGVRVPADAMLGGAEGEGAGFGIAMNGLN
EEEECCCCCCCCCCCHHHCCCCCCCHHHHHHHHCCCCHHHHCCCCCCCCCCEEEEEECCC
GGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGSPLLDEPTIRFALADMATGLETSRMMLW
CCEEEEEEECCCCHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHH
RAAGALDADDPDKVELCAMAKRYVTDTCFEVADKALQLHGGYGYLREYGLEKIVRDLRVH
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RILEGTNEIMRVVIGRAEAARFRATA
HHHHHHHHHHHHHHCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]