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The map label for this gene is nusG

Identifier: 41410209

GI number: 41410209

Start: 4582676

End: 4583446

Strand: Direct

Name: nusG

Synonym: MAP4111

Alternate gene names: 41410209

Gene position: 4582676-4583446 (Clockwise)

Preceding gene: 41410208

Following gene: 41410210

Centisome position: 94.88

GC content: 68.09

Gene sequence:

>771_bases
GTGACTACCTTCGACGGTGACCCGTCCGCGGGTGACGCGGTCGACCTGAGGGAGACCGACGAGGCCACCGAGGCCGCCGA
CGAGGCTGCCGAGACCACCGAGGACGCCGCCGAGTCGGCCGAGACGCAGGGCGAACCGGCCGAAGAGGTTGACCCGGCCG
CCGCGCTCAAGGCCGAACTGCGCAGCAAGCCCGGCGACTGGTACGTCATCCACTCCTACGCGGGATACGAGAACAAGGTC
AAAGCCAACCTGGAAACGCGGGTGCAGAACCTCGACGTCGGGGACTACATCTTCCAGGTCGAGGTGCCCACCGAAGAGGT
CACCGAGATCAAGAACGGCCAGCGCAAGCAGGTCAACCGCAAGGTGCTGCCCGGCTACATCCTGGTGCGGATGGATCTGA
CCGACGACTCGTGGGCCGCGGTGCGCAACACGCCCGGGGTCACCGGGTTCGTCGGCGCGACGTCGCGCCCGTCGGCGCTG
TCGCTCGACGACGTGGTGAAGTTCCTGCTGCCGCGCGGCGCGACGAAGAAGGTCGCCAAGGGTGCGGCCAGCACCGCGGC
CGCCGCCGAGGCGGGCGGCCTGGAGCGTCCGGCCATCGAGGTCGACTACGAGGTGGGCGAGTCAGTGACGGTGATGGACG
GACCGTTCGCCACCCTGCCGGCCACCATCAGCGAGGTCAACGGCGAGCAGCAGAAGCTCAAGGTGCTGGTGTCCATCTTC
GGCCGCGAAACGCCGGTGGAACTGACCTTCAGCCAAGTCTCCAAGCTCTGA

Upstream 100 bases:

>100_bases
GCTGGTCGGCCTGGCGGATTTCGGCCTGACCAAGCTGGTGCTGCTGGTGTTCGGCTGAGCGAGTGACGCCGCTTTGAAAG
TGACAGAGAGGACTCAACCC

Downstream 100 bases:

>100_bases
ACCGGCGCCGGCGCCGGGCACAAACCAGGAAGGACAACAACATCTCATGGCCCCGAAGAAGAAAGTCGTCGGGCTGATCA
AGCTCCAGATCCAGGCGGGG

Product: transcription antitermination protein NusG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MTTFDGDPSAGDAVDLRETDEATEAADEAAETTEDAAESAETQGEPAEEVDPAAALKAELRSKPGDWYVIHSYAGYENKV
KANLETRVQNLDVGDYIFQVEVPTEEVTEIKNGQRKQVNRKVLPGYILVRMDLTDDSWAAVRNTPGVTGFVGATSRPSAL
SLDDVVKFLLPRGATKKVAKGAASTAAAAEAGGLERPAIEVDYEVGESVTVMDGPFATLPATISEVNGEQQKLKVLVSIF
GRETPVELTFSQVSKL

Sequences:

>Translated_256_residues
MTTFDGDPSAGDAVDLRETDEATEAADEAAETTEDAAESAETQGEPAEEVDPAAALKAELRSKPGDWYVIHSYAGYENKV
KANLETRVQNLDVGDYIFQVEVPTEEVTEIKNGQRKQVNRKVLPGYILVRMDLTDDSWAAVRNTPGVTGFVGATSRPSAL
SLDDVVKFLLPRGATKKVAKGAASTAAAAEAGGLERPAIEVDYEVGESVTVMDGPFATLPATISEVNGEQQKLKVLVSIF
GRETPVELTFSQVSKL
>Mature_255_residues
TTFDGDPSAGDAVDLRETDEATEAADEAAETTEDAAESAETQGEPAEEVDPAAALKAELRSKPGDWYVIHSYAGYENKVK
ANLETRVQNLDVGDYIFQVEVPTEEVTEIKNGQRKQVNRKVLPGYILVRMDLTDDSWAAVRNTPGVTGFVGATSRPSALS
LDDVVKFLLPRGATKKVAKGAASTAAAAEAGGLERPAIEVDYEVGESVTVMDGPFATLPATISEVNGEQQKLKVLVSIFG
RETPVELTFSQVSKL

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase [H]

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nusG family [H]

Homologues:

Organism=Escherichia coli, GI1790414, Length=190, Percent_Identity=42.1052631578947, Blast_Score=145, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF02357 NusG [H]

EC number: NA

Molecular weight: Translated: 27365; Mature: 27233

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFDGDPSAGDAVDLRETDEATEAADEAAETTEDAAESAETQGEPAEEVDPAAALKAEL
CCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHH
RSKPGDWYVIHSYAGYENKVKANLETRVQNLDVGDYIFQVEVPTEEVTEIKNGQRKQVNR
HCCCCCEEEEEEECCCCCEEHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCHHHHHHH
KVLPGYILVRMDLTDDSWAAVRNTPGVTGFVGATSRPSALSLDDVVKFLLPRGATKKVAK
CCCCCEEEEEEECCCCCCHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHH
GAASTAAAAEAGGLERPAIEVDYEVGESVTVMDGPFATLPATISEVNGEQQKLKVLVSIF
CCHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCCHHHCHHHHHCCCHHHHHHHHHHHH
GRETPVELTFSQVSKL
CCCCCEEEEHHHHHCC
>Mature Secondary Structure 
TTFDGDPSAGDAVDLRETDEATEAADEAAETTEDAAESAETQGEPAEEVDPAAALKAEL
CCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHH
RSKPGDWYVIHSYAGYENKVKANLETRVQNLDVGDYIFQVEVPTEEVTEIKNGQRKQVNR
HCCCCCEEEEEEECCCCCEEHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCHHHHHHH
KVLPGYILVRMDLTDDSWAAVRNTPGVTGFVGATSRPSALSLDDVVKFLLPRGATKKVAK
CCCCCEEEEEEECCCCCCHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHH
GAASTAAAAEAGGLERPAIEVDYEVGESVTVMDGPFATLPATISEVNGEQQKLKVLVSIF
CCHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCCHHHCHHHHHCCCHHHHHHHHHHHH
GRETPVELTFSQVSKL
CCCCCEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]