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The map label for this gene is fixC [C]

Identifier: 41410155

GI number: 41410155

Start: 4517181

End: 4518419

Strand: Reverse

Name: fixC [C]

Synonym: MAP4057c

Alternate gene names: 41410155

Gene position: 4518419-4517181 (Counterclockwise)

Preceding gene: 41410158

Following gene: 41410154

Centisome position: 93.55

GC content: 74.41

Gene sequence:

>1239_bases
ATGACGACGGCAGCGACCCGAGCCGATCTGGTGGTGGTGGGCGCCGGGCCCGCCGGATCCGCCGCGGCGGCCTGGGCCGC
GCGCGCGGGGCATGACGTGCTGGTCGTCGATGCGGCGCGCTTTCCCCGCGACAAGGCCTGCGGCGACGGGCTGACCCCGC
GCGCCGTCGCCGAGTGCGAACGCCTGGGCCTGGGCGGCTGGCTGGACAGCCGCATCCGGCACCGCGGGCTGCGGATGAGC
GGGTTCGGCGCCCAGGTGCAGGTCGACTGGCCCGGCCCGTCGTTCCCGTCCACCGGCAGCGCGGTGGCCCGCACGGAGTT
GGACGACCGGATCCGCAGGGTCGCCGAGGATTCCGGGGCGCGGATGCTGCTGGGAACCAAAGCCGTTGGCGTGCAGCGTG
ACTCGTCGGGCGCGGTGAGGGCGCTGACGTTGGCCGACGGCACCGGGGTGCAATGCCGTCAGCTGATCGTGGCCGACGGG
GCGCGTTCGTCGCTGGGCCGCGCGCTGGGCCGACGCTGGCATCAGGAGACGGTGTACGGCGTGGCCGCCCGCGGCTACCT
GAGCACCCCGCACGCCGACGACCCCTGGCTGACGTCGCACCTGGAACTGCGCGGACCCGACGGCGCCCGGGACAAGGTGC
TGCCCGGCTACGGCTGGATCTTCCCGCTCGGCAACGGTGAGGTGAACATCGGCGTCGGGGCGCTGTCGACGTCGAGGCGA
CCGGCCGAGCTGGCGCTGCGGCCGCTGATCGACCACTACACGGACCTGCGCCGCGACGAGTGGGGCTTCGTCGGCAGACC
CCGGGCGGTCGCTTCGGCGCTGCTGCCGATGGGCGGCGCGGTGTCCGGGGTGGCCGGGCCCAACTGGATGCTGATCGGCG
ACGCGGCGGCCTGTGTGAACCCGCTCAACGGCGAGGGCATCGACTACGGAATGGAGACGGGACGGCTGGCCGCGGGCCTG
CTGGGGTGCCCGGACCTGTCGCAGGAGTGGCCGGCGCTGCTGCGGGAGCACTACGCGCGCGGCTTCTCGGTGGCGCGCCG
GCTGGCGTTGCTGCTGACCTACCAGCGGTTCCTGCCCGCGACGGGGCCGGTCGCGATGCGTTCCACGACGCTGATGAGGA
TCGCGGTGCGGGTGATGGCCAACCTGGTCACCGACGACGACGCGGACTGGGTGGCGCGGGCGTGGCGGGGCGCCGGGCGG
CTGTCGCGGCTGATCGATCGGCGGGCACCGTTCAGCTGA

Upstream 100 bases:

>100_bases
GACGCCGTCGCGCACGGTCGCCGCGAAAGCCGGGTCACCGAAATCCACGCCCGCCACCACCGTCGCCGGAGTATTCACCC
GACCAAACATACTGGTGTGC

Downstream 100 bases:

>100_bases
ACGACCCTGTCCAGGCGTGTATAGTCCGGCTAATGAAGGGAACGATGCTGGCTACTATCGGTGCCGCCGCCGTTGCTGCT
TTCGCGCTGGCCGCGCCCGC

Product: hypothetical protein

Products: NA

Alternate protein names: DGGGPL reductase 1; 2,3-di-O-geranylgeranylglyceryl phosphate reductase 1; Geranylgeranyl reductase 1; GGR 1 [H]

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MTTAATRADLVVVGAGPAGSAAAAWAARAGHDVLVVDAARFPRDKACGDGLTPRAVAECERLGLGGWLDSRIRHRGLRMS
GFGAQVQVDWPGPSFPSTGSAVARTELDDRIRRVAEDSGARMLLGTKAVGVQRDSSGAVRALTLADGTGVQCRQLIVADG
ARSSLGRALGRRWHQETVYGVAARGYLSTPHADDPWLTSHLELRGPDGARDKVLPGYGWIFPLGNGEVNIGVGALSTSRR
PAELALRPLIDHYTDLRRDEWGFVGRPRAVASALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEGIDYGMETGRLAAGL
LGCPDLSQEWPALLREHYARGFSVARRLALLLTYQRFLPATGPVAMRSTTLMRIAVRVMANLVTDDDADWVARAWRGAGR
LSRLIDRRAPFS

Sequences:

>Translated_412_residues
MTTAATRADLVVVGAGPAGSAAAAWAARAGHDVLVVDAARFPRDKACGDGLTPRAVAECERLGLGGWLDSRIRHRGLRMS
GFGAQVQVDWPGPSFPSTGSAVARTELDDRIRRVAEDSGARMLLGTKAVGVQRDSSGAVRALTLADGTGVQCRQLIVADG
ARSSLGRALGRRWHQETVYGVAARGYLSTPHADDPWLTSHLELRGPDGARDKVLPGYGWIFPLGNGEVNIGVGALSTSRR
PAELALRPLIDHYTDLRRDEWGFVGRPRAVASALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEGIDYGMETGRLAAGL
LGCPDLSQEWPALLREHYARGFSVARRLALLLTYQRFLPATGPVAMRSTTLMRIAVRVMANLVTDDDADWVARAWRGAGR
LSRLIDRRAPFS
>Mature_411_residues
TTAATRADLVVVGAGPAGSAAAAWAARAGHDVLVVDAARFPRDKACGDGLTPRAVAECERLGLGGWLDSRIRHRGLRMSG
FGAQVQVDWPGPSFPSTGSAVARTELDDRIRRVAEDSGARMLLGTKAVGVQRDSSGAVRALTLADGTGVQCRQLIVADGA
RSSLGRALGRRWHQETVYGVAARGYLSTPHADDPWLTSHLELRGPDGARDKVLPGYGWIFPLGNGEVNIGVGALSTSRRP
AELALRPLIDHYTDLRRDEWGFVGRPRAVASALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEGIDYGMETGRLAAGLL
GCPDLSQEWPALLREHYARGFSVARRLALLLTYQRFLPATGPVAMRSTTLMRIAVRVMANLVTDDDADWVARAWRGAGRL
SRLIDRRAPFS

Specific function: Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR011777
- InterPro:   IPR003042 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 43896; Mature: 43764

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAATRADLVVVGAGPAGSAAAAWAARAGHDVLVVDAARFPRDKACGDGLTPRAVAECE
CCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
RLGLGGWLDSRIRHRGLRMSGFGAQVQVDWPGPSFPSTGSAVARTELDDRIRRVAEDSGA
HCCCCCHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
RMLLGTKAVGVQRDSSGAVRALTLADGTGVQCRQLIVADGARSSLGRALGRRWHQETVYG
EEEEECCEECEEECCCCCEEEEEECCCCCCHHHHEEEECCCHHHHHHHHHHHHHHHHHHH
VAARGYLSTPHADDPWLTSHLELRGPDGARDKVLPGYGWIFPLGNGEVNIGVGALSTSRR
HHCCCCCCCCCCCCCCEECEEEEECCCCCCCCCCCCCCEEEECCCCEEEEEEEECCCCCC
PAELALRPLIDHYTDLRRDEWGFVGRPRAVASALLPMGGAVSGVAGPNWMLIGDAAACVN
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHCC
PLNGEGIDYGMETGRLAAGLLGCPDLSQEWPALLREHYARGFSVARRLALLLTYQRFLPA
CCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TGPVAMRSTTLMRIAVRVMANLVTDDDADWVARAWRGAGRLSRLIDRRAPFS
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTAATRADLVVVGAGPAGSAAAAWAARAGHDVLVVDAARFPRDKACGDGLTPRAVAECE
CCCCCCCCEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
RLGLGGWLDSRIRHRGLRMSGFGAQVQVDWPGPSFPSTGSAVARTELDDRIRRVAEDSGA
HCCCCCHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
RMLLGTKAVGVQRDSSGAVRALTLADGTGVQCRQLIVADGARSSLGRALGRRWHQETVYG
EEEEECCEECEEECCCCCEEEEEECCCCCCHHHHEEEECCCHHHHHHHHHHHHHHHHHHH
VAARGYLSTPHADDPWLTSHLELRGPDGARDKVLPGYGWIFPLGNGEVNIGVGALSTSRR
HHCCCCCCCCCCCCCCEECEEEEECCCCCCCCCCCCCCEEEECCCCEEEEEEEECCCCCC
PAELALRPLIDHYTDLRRDEWGFVGRPRAVASALLPMGGAVSGVAGPNWMLIGDAAACVN
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHCC
PLNGEGIDYGMETGRLAAGLLGCPDLSQEWPALLREHYARGFSVARRLALLLTYQRFLPA
CCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TGPVAMRSTTLMRIAVRVMANLVTDDDADWVARAWRGAGRLSRLIDRRAPFS
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a quinone or similar compound as acceptor [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA