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The map label for this gene is fadE20_3

Identifier: 41409975

GI number: 41409975

Start: 4338971

End: 4340119

Strand: Reverse

Name: fadE20_3

Synonym: MAP3877c

Alternate gene names: 41409975

Gene position: 4340119-4338971 (Counterclockwise)

Preceding gene: 41409976

Following gene: 41409974

Centisome position: 89.86

GC content: 67.97

Gene sequence:

>1149_bases
ATGGCCGCACACCTGCAGTACACCTCCGAGCATCACCAGTTCCGGGAGCTGGTCCGCGATTTCGTGCAACGGACGGTCGT
GCCCAATCACGAGAAGTGGGAACGCGACGGCCAGTGGGACCGGTCGCTGTTCGTCGAGGCAGGCAAACTGGGGCTGCTGG
GCTTTTCGGTGCCCGAGCGGTTGGGCGGCCCGGGGGTCGACGACTTTCGCTACAACGCGATCGTGGTCGACGAGTTGCAG
CGGGCCGGCGCGGCCGCCGAGGCCATCGCCTTCTCGCTGCAGAACGACATCGTGCTGCCCTACCTCGTCGAGCTGACCAC
ACCCGAGCAACAACGGCGCTGGCTGCCCGGCGTGGTGACCGGCGAGACGGTGCTCGGGATCGCCATGACCGAGCCCGGCA
CCGGCAGCGACCTGGCCGGGATCCGCACCACCGCGGTGCGAGACGGCGATCACTACCTGGTCAACGGCGCCAAGACGTTC
ATCTCCAACGGGCAGGTGGGCGACCTGTTCGTGGTCGCGGTGCGCACCGCACCGGACCGGCACAAGGGGCTTTCGCTGCT
GGTCGTGGACGCGGACACGCCGGGCTTCGGCCGGGGCCGCAACCTGGAGAAGATCGGCCTGCACGCCCAGGACACCAGCG
AGCTGAGCTTCACCGACATGCGGGTGCCGGCCGAGAACCTGCTCGAGGCGGAAGGCCGGGGCTTCTACCAGCTGATGAAA
AACCTTCCCCAGGAACGGCTTTCGCTGGCCGTGGGCGCGGTCGCCGCCGCCGAGGCAGTATTCGCCGAGACGCTGGACTA
CGTCAAGCAGTGGCACGCCTTCGGCGCGCCCATCGCCGCCTTCCAGAACAGTCAATTCGTGCTCGCCGAACTGGCCACCG
AAATCGACGTTGCCCGCACTTATCTCGACGACTGCCTGGCCGCGCACCTGGCCGGCGAGCTGACCGCGGCGCGGGCCGCC
CGGCTGAAATGGTGGACCACCGATCTGCAGGTCCGCACCGCCGACCGCTGCCTGCAGTTGCACGGCGGATACGGCTACAT
GCGCGAGTACGGCGTGGCGCGGGCGTTCGTCGACGCCCGCATCCAGACCATCTACGGCGGCACCAACGAGATCATGAAGA
CCATCATCGCCAAGGACCTGGGCCTCTAG

Upstream 100 bases:

>100_bases
TCGGTGCTGACCTACGAGGGCACGCCGGAGATGCATCAGCTCGTCCTCGGCCAGGCATTCACCGGCGCCGACGCCTTCCG
CTGACCCAGAGCAGCACCCG

Downstream 100 bases:

>100_bases
CGGCATGGCCGTCGACTACAGCGAACTGCCCGCCGAGGAGGCCGTGCGCGCCGCACGGGCCGGCGCGCGGCGCCGCCAGG
TGCTCGACGCCGCGGTCAAG

Product: FadE20_3

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MAAHLQYTSEHHQFRELVRDFVQRTVVPNHEKWERDGQWDRSLFVEAGKLGLLGFSVPERLGGPGVDDFRYNAIVVDELQ
RAGAAAEAIAFSLQNDIVLPYLVELTTPEQQRRWLPGVVTGETVLGIAMTEPGTGSDLAGIRTTAVRDGDHYLVNGAKTF
ISNGQVGDLFVVAVRTAPDRHKGLSLLVVDADTPGFGRGRNLEKIGLHAQDTSELSFTDMRVPAENLLEAEGRGFYQLMK
NLPQERLSLAVGAVAAAEAVFAETLDYVKQWHAFGAPIAAFQNSQFVLAELATEIDVARTYLDDCLAAHLAGELTAARAA
RLKWWTTDLQVRTADRCLQLHGGYGYMREYGVARAFVDARIQTIYGGTNEIMKTIIAKDLGL

Sequences:

>Translated_382_residues
MAAHLQYTSEHHQFRELVRDFVQRTVVPNHEKWERDGQWDRSLFVEAGKLGLLGFSVPERLGGPGVDDFRYNAIVVDELQ
RAGAAAEAIAFSLQNDIVLPYLVELTTPEQQRRWLPGVVTGETVLGIAMTEPGTGSDLAGIRTTAVRDGDHYLVNGAKTF
ISNGQVGDLFVVAVRTAPDRHKGLSLLVVDADTPGFGRGRNLEKIGLHAQDTSELSFTDMRVPAENLLEAEGRGFYQLMK
NLPQERLSLAVGAVAAAEAVFAETLDYVKQWHAFGAPIAAFQNSQFVLAELATEIDVARTYLDDCLAAHLAGELTAARAA
RLKWWTTDLQVRTADRCLQLHGGYGYMREYGVARAFVDARIQTIYGGTNEIMKTIIAKDLGL
>Mature_381_residues
AAHLQYTSEHHQFRELVRDFVQRTVVPNHEKWERDGQWDRSLFVEAGKLGLLGFSVPERLGGPGVDDFRYNAIVVDELQR
AGAAAEAIAFSLQNDIVLPYLVELTTPEQQRRWLPGVVTGETVLGIAMTEPGTGSDLAGIRTTAVRDGDHYLVNGAKTFI
SNGQVGDLFVVAVRTAPDRHKGLSLLVVDADTPGFGRGRNLEKIGLHAQDTSELSFTDMRVPAENLLEAEGRGFYQLMKN
LPQERLSLAVGAVAAAEAVFAETLDYVKQWHAFGAPIAAFQNSQFVLAELATEIDVARTYLDDCLAAHLAGELTAARAAR
LKWWTTDLQVRTADRCLQLHGGYGYMREYGVARAFVDARIQTIYGGTNEIMKTIIAKDLGL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=46.9496021220159, Blast_Score=349, Evalue=3e-96,
Organism=Homo sapiens, GI7656849, Length=373, Percent_Identity=31.9034852546917, Blast_Score=212, Evalue=6e-55,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=30.0531914893617, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI226958414, Length=336, Percent_Identity=31.25, Blast_Score=195, Evalue=7e-50,
Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=30.1333333333333, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=31.7333333333333, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI187960098, Length=380, Percent_Identity=30, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI4557231, Length=380, Percent_Identity=30, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI4557235, Length=343, Percent_Identity=31.1953352769679, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI76496475, Length=343, Percent_Identity=31.1953352769679, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI21361497, Length=378, Percent_Identity=28.042328042328, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI4503943, Length=380, Percent_Identity=27.3684210526316, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI7669494, Length=367, Percent_Identity=27.2479564032698, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI48976061, Length=360, Percent_Identity=29.4444444444444, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI211971008, Length=360, Percent_Identity=29.4444444444444, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI38505218, Length=283, Percent_Identity=28.2685512367491, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI87081958, Length=351, Percent_Identity=29.6296296296296, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1786223, Length=350, Percent_Identity=26.5714285714286, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI87082384, Length=285, Percent_Identity=27.719298245614, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17538396, Length=374, Percent_Identity=31.0160427807487, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17534899, Length=369, Percent_Identity=31.9783197831978, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17570075, Length=380, Percent_Identity=32.8947368421053, Blast_Score=197, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17551932, Length=379, Percent_Identity=32.4538258575198, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17569725, Length=382, Percent_Identity=30.8900523560209, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17505929, Length=379, Percent_Identity=33.245382585752, Blast_Score=188, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17508101, Length=374, Percent_Identity=28.3422459893048, Blast_Score=184, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17533517, Length=370, Percent_Identity=31.0810810810811, Blast_Score=181, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI17506239, Length=369, Percent_Identity=29.2682926829268, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71990804, Length=250, Percent_Identity=33.6, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71985184, Length=388, Percent_Identity=27.5773195876289, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71982178, Length=279, Percent_Identity=28.3154121863799, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17534353, Length=380, Percent_Identity=27.3684210526316, Blast_Score=134, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI71985192, Length=344, Percent_Identity=26.1627906976744, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=28.1385281385281, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17562446, Length=399, Percent_Identity=26.8170426065163, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17531909, Length=239, Percent_Identity=24.6861924686192, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21355753, Length=377, Percent_Identity=32.0954907161804, Blast_Score=207, Evalue=8e-54,
Organism=Drosophila melanogaster, GI21356377, Length=386, Percent_Identity=31.8652849740933, Blast_Score=202, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24666513, Length=372, Percent_Identity=30.9139784946237, Blast_Score=198, Evalue=6e-51,
Organism=Drosophila melanogaster, GI24660351, Length=383, Percent_Identity=31.5926892950392, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24646207, Length=383, Percent_Identity=30.8093994778068, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI281363737, Length=350, Percent_Identity=29.1428571428571, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI19920834, Length=383, Percent_Identity=29.242819843342, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42013; Mature: 41882

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAHLQYTSEHHQFRELVRDFVQRTVVPNHEKWERDGQWDRSLFVEAGKLGLLGFSVPER
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHCCCCEEEEECCCHHH
LGGPGVDDFRYNAIVVDELQRAGAAAEAIAFSLQNDIVLPYLVELTTPEQQRRWLPGVVT
HCCCCCCCCEECEEEHHHHHHCCCHHHHHHHHHCCCCEEEEEEEECCCHHHHCCCCCEEE
GETVLGIAMTEPGTGSDLAGIRTTAVRDGDHYLVNGAKTFISNGQVGDLFVVAVRTAPDR
CCEEEEEEEECCCCCCCCCCCEEEEEECCCEEEECCHHHHHCCCCCCCEEEEEEECCCCC
HKGLSLLVVDADTPGFGRGRNLEKIGLHAQDTSELSFTDMRVPAENLLEAEGRGFYQLMK
CCCCEEEEEECCCCCCCCCCCCHHHCCCCCCCCCCCEEECCCCHHHHHHHCCCCHHHHHH
NLPQERLSLAVGAVAAAEAVFAETLDYVKQWHAFGAPIAAFQNSQFVLAELATEIDVART
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHH
YLDDCLAAHLAGELTAARAARLKWWTTDLQVRTADRCLQLHGGYGYMREYGVARAFVDAR
HHHHHHHHHHHHHHHHHHHHHEEEEECCEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHH
IQTIYGGTNEIMKTIIAKDLGL
HHEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AAHLQYTSEHHQFRELVRDFVQRTVVPNHEKWERDGQWDRSLFVEAGKLGLLGFSVPER
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHCCCCEEEEECCCHHH
LGGPGVDDFRYNAIVVDELQRAGAAAEAIAFSLQNDIVLPYLVELTTPEQQRRWLPGVVT
HCCCCCCCCEECEEEHHHHHHCCCHHHHHHHHHCCCCEEEEEEEECCCHHHHCCCCCEEE
GETVLGIAMTEPGTGSDLAGIRTTAVRDGDHYLVNGAKTFISNGQVGDLFVVAVRTAPDR
CCEEEEEEEECCCCCCCCCCCEEEEEECCCEEEECCHHHHHCCCCCCCEEEEEEECCCCC
HKGLSLLVVDADTPGFGRGRNLEKIGLHAQDTSELSFTDMRVPAENLLEAEGRGFYQLMK
CCCCEEEEEECCCCCCCCCCCCHHHCCCCCCCCCCCEEECCCCHHHHHHHCCCCHHHHHH
NLPQERLSLAVGAVAAAEAVFAETLDYVKQWHAFGAPIAAFQNSQFVLAELATEIDVART
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHH
YLDDCLAAHLAGELTAARAARLKWWTTDLQVRTADRCLQLHGGYGYMREYGVARAFVDAR
HHHHHHHHHHHHHHHHHHHHHEEEEECCEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHH
IQTIYGGTNEIMKTIIAKDLGL
HHEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]