Click here to switch to the map view.

The map label for this gene is dnaK [H]

Identifier: 41409930

GI number: 41409930

Start: 4285426

End: 4287123

Strand: Reverse

Name: dnaK [H]

Synonym: MAP3832c

Alternate gene names: 41409930

Gene position: 4287123-4285426 (Counterclockwise)

Preceding gene: 41409931

Following gene: 41409929

Centisome position: 88.76

GC content: 73.79

Gene sequence:

>1698_bases
GTGCGGGACATGAGCGAGCCGCTCGGACTGTCGATCGGAGTGGCCAACCTGGTGGCGGCCCGCGCCGGCAGCGTCCCGGT
GATCCGCAGCTCGGTGCTGACGCTGTTCGAGCAGCGGCCCACCGAAGTCGGCCTGCCCGACGAGAACCCGAACCTGACCG
AACCCGGGCTGGTGTTGCGGGGGTTCGTCGAGCGGGTCGGCGACCGGGCCCCGCTGGTGGCGGCCGACGGCACCAAGTAC
CTGGGCGCGGCGCTGACGGTCGAGGCGGTCGAGGCGATGGCCCGCGCGGTCGGCTACGGGGCGCCGATCACCATCGCGGT
GCCCGCCTACTGGTCCGACGACCAGTTCGCCGCGCTGCGCGAGGAGTTCTTCGCCCAGTCCGACCTCGCGCGGGAGGGGG
TGGCGCCGATGCTGGTTTCCGACGCCACGGCCGCGCTCGCGATGCTGCGCGGCACGCCGGGATTCCCGTCCGACGGCGTG
ATTGCGCTGTGTGACTTCGGCGCCGGCGGCACCACCGTCACCCTGATGGACGGCCGGGCCGGCTTCGCGCCGGTCGGCCC
GTCGCTGCGGTACACCGACTTCTCCGGCGACGCGATCGACCAGCTCGTCCTCGACCACCTGCTGGCCTCCGACGTCAGCA
CCGCCATGCTGGGCGGGTCCGGGCGGATCGGGTCGCAGAGCCGGCTGCTCGGCGCCTGCCGTCGGGCCAAGGAGCAGCTG
TCGACGGCCGTGGCGGCCACGGTGGCCGGGGCGCCCGGACAGGGCGCCCAGCTGACCCGCGCGGAGTTCGAGCAACTGAT
CTCCACACCGCTGGACCGGTTCCTGGATTGGTGCCAGGAAGCGTTGCGGCGCAACGGGATTGGTAACTCCACTCTGCGTG
GGGTGGCGATCGTCGGCGGCGGGGCGAGCATCCCGCTGCTCACCGCGCGGTTGTCGGGACGGTTCGGGGTGCCGGTGCAC
AGCACCGCGCAGCCGGGATTGAGCGCCGCGCTGGGCGCGGCGACGCTGGGTGCGCAATACGCGTCGGGGGCCGCTCCGAC
GGCCGCCGCCGCCGCCGCGGTGGAGACACCCACCGAGATGGTCGGCGCCGGCGGGCTCGACATGACCCAGGCCGCCTGGG
CCGCCCAGGCCACCGACGTGGACGACGCCCTGGCGTGGTCGCAGGACGCCGACACCTCCGACGAGCCGGTGCCCTACACC
GGCCGCGACGCCACCGGCGAATATGCCAGTGAGGCAAGACGATTCGACGACGCCGCGGCGGGCGGGCTGCCCTGGTACAA
GCGCACCGCGCTGGTGTTGAGCGTGGCCGGGGCCGGCGCGGCGGTGCTGATCGCCCTGGTGTTGGCGATTAACCTGCTGC
TCACCAAGTCCACCCAGGACCGGCCCACGTCGCCGCCCAGCACGCCCGCCCCGCCGCAAACCGTGACGATCACCGGGCCG
AACGACAGCACCACCGTCACCGTCGTGCCGGCGCCGCCACCGCCGTCCAGCGAGGCGCCGCCGCCCCCGGCCACCACCAC
GACAGCGCCGCCGGAGCCGTCGACCACCACGACAACTACGACGCCCCCGCCGAGCAGCACGACCACGACCAGCGCCGCGC
CCACCACGACGGCGCAGCCGAGCACCACCAGCGCGGCGTCGACGACCACCCGGGTGCGCCCGATTCCGCCGATCTTTCAA
CCACCTTTCGGCCGTTAA

Upstream 100 bases:

>100_bases
TCCGCAGGTGCCGACCGTCATCACGGTGCCGCCGGGTCTGCGTTAGGCCGCGGGGCGGCGCCCTACACTCGCTGCAATCC
AACCGACGACTGACACAGGG

Downstream 100 bases:

>100_bases
CACCGCCCGGTAAAGGTCATTCGGCGAAAAGCCGGTGGCGTCGATCACTCCGACAAACGTCACATGGCCGCGGGCGGGTA
CCAACGCAGCAGGCCAGGGG

Product: hypothetical protein

Products: NA

Alternate protein names: HSP70; Heat shock 70 kDa protein; Heat shock protein 70 [H]

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MRDMSEPLGLSIGVANLVAARAGSVPVIRSSVLTLFEQRPTEVGLPDENPNLTEPGLVLRGFVERVGDRAPLVAADGTKY
LGAALTVEAVEAMARAVGYGAPITIAVPAYWSDDQFAALREEFFAQSDLAREGVAPMLVSDATAALAMLRGTPGFPSDGV
IALCDFGAGGTTVTLMDGRAGFAPVGPSLRYTDFSGDAIDQLVLDHLLASDVSTAMLGGSGRIGSQSRLLGACRRAKEQL
STAVAATVAGAPGQGAQLTRAEFEQLISTPLDRFLDWCQEALRRNGIGNSTLRGVAIVGGGASIPLLTARLSGRFGVPVH
STAQPGLSAALGAATLGAQYASGAAPTAAAAAAVETPTEMVGAGGLDMTQAAWAAQATDVDDALAWSQDADTSDEPVPYT
GRDATGEYASEARRFDDAAAGGLPWYKRTALVLSVAGAGAAVLIALVLAINLLLTKSTQDRPTSPPSTPAPPQTVTITGP
NDSTTVTVVPAPPPPSSEAPPPPATTTTAPPEPSTTTTTTTPPPSSTTTTSAAPTTTAQPSTTSAASTTTRVRPIPPIFQ
PPFGR

Sequences:

>Translated_565_residues
MRDMSEPLGLSIGVANLVAARAGSVPVIRSSVLTLFEQRPTEVGLPDENPNLTEPGLVLRGFVERVGDRAPLVAADGTKY
LGAALTVEAVEAMARAVGYGAPITIAVPAYWSDDQFAALREEFFAQSDLAREGVAPMLVSDATAALAMLRGTPGFPSDGV
IALCDFGAGGTTVTLMDGRAGFAPVGPSLRYTDFSGDAIDQLVLDHLLASDVSTAMLGGSGRIGSQSRLLGACRRAKEQL
STAVAATVAGAPGQGAQLTRAEFEQLISTPLDRFLDWCQEALRRNGIGNSTLRGVAIVGGGASIPLLTARLSGRFGVPVH
STAQPGLSAALGAATLGAQYASGAAPTAAAAAAVETPTEMVGAGGLDMTQAAWAAQATDVDDALAWSQDADTSDEPVPYT
GRDATGEYASEARRFDDAAAGGLPWYKRTALVLSVAGAGAAVLIALVLAINLLLTKSTQDRPTSPPSTPAPPQTVTITGP
NDSTTVTVVPAPPPPSSEAPPPPATTTTAPPEPSTTTTTTTPPPSSTTTTSAAPTTTAQPSTTSAASTTTRVRPIPPIFQ
PPFGR
>Mature_565_residues
MRDMSEPLGLSIGVANLVAARAGSVPVIRSSVLTLFEQRPTEVGLPDENPNLTEPGLVLRGFVERVGDRAPLVAADGTKY
LGAALTVEAVEAMARAVGYGAPITIAVPAYWSDDQFAALREEFFAQSDLAREGVAPMLVSDATAALAMLRGTPGFPSDGV
IALCDFGAGGTTVTLMDGRAGFAPVGPSLRYTDFSGDAIDQLVLDHLLASDVSTAMLGGSGRIGSQSRLLGACRRAKEQL
STAVAATVAGAPGQGAQLTRAEFEQLISTPLDRFLDWCQEALRRNGIGNSTLRGVAIVGGGASIPLLTARLSGRFGVPVH
STAQPGLSAALGAATLGAQYASGAAPTAAAAAAVETPTEMVGAGGLDMTQAAWAAQATDVDDALAWSQDADTSDEPVPYT
GRDATGEYASEARRFDDAAAGGLPWYKRTALVLSVAGAGAAVLIALVLAINLLLTKSTQDRPTSPPSTPAPPQTVTITGP
NDSTTVTVVPAPPPPSSEAPPPPATTTTAPPEPSTTTTTTTPPPSSTTTTSAAPTTTAQPSTTSAASTTTRVRPIPPIFQ
PPFGR

Specific function: Acts as a chaperone [H]

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Homo sapiens, GI24234688, Length=280, Percent_Identity=25, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI34419635, Length=248, Percent_Identity=27.4193548387097, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1788875, Length=268, Percent_Identity=30.9701492537313, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786196, Length=387, Percent_Identity=23.2558139534884, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562024, Length=244, Percent_Identity=25.4098360655738, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012725
- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 57461; Mature: 57461

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDMSEPLGLSIGVANLVAARAGSVPVIRSSVLTLFEQRPTEVGLPDENPNLTEPGLVLR
CCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
GFVERVGDRAPLVAADGTKYLGAALTVEAVEAMARAVGYGAPITIAVPAYWSDDQFAALR
HHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
EEFFAQSDLAREGVAPMLVSDATAALAMLRGTPGFPSDGVIALCDFGAGGTTVTLMDGRA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEEEEECCCC
GFAPVGPSLRYTDFSGDAIDQLVLDHLLASDVSTAMLGGSGRIGSQSRLLGACRRAKEQL
CCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
STAVAATVAGAPGQGAQLTRAEFEQLISTPLDRFLDWCQEALRRNGIGNSTLRGVAIVGG
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC
GASIPLLTARLSGRFGVPVHSTAQPGLSAALGAATLGAQYASGAAPTAAAAAAVETPTEM
CCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHH
VGAGGLDMTQAAWAAQATDVDDALAWSQDADTSDEPVPYTGRDATGEYASEARRFDDAAA
HCCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GGLPWYKRTALVLSVAGAGAAVLIALVLAINLLLTKSTQDRPTSPPSTPAPPQTVTITGP
CCCCHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECC
NDSTTVTVVPAPPPPSSEAPPPPATTTTAPPEPSTTTTTTTPPPSSTTTTSAAPTTTAQP
CCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
STTSAASTTTRVRPIPPIFQPPFGR
CCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRDMSEPLGLSIGVANLVAARAGSVPVIRSSVLTLFEQRPTEVGLPDENPNLTEPGLVLR
CCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
GFVERVGDRAPLVAADGTKYLGAALTVEAVEAMARAVGYGAPITIAVPAYWSDDQFAALR
HHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
EEFFAQSDLAREGVAPMLVSDATAALAMLRGTPGFPSDGVIALCDFGAGGTTVTLMDGRA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEEEEECCCC
GFAPVGPSLRYTDFSGDAIDQLVLDHLLASDVSTAMLGGSGRIGSQSRLLGACRRAKEQL
CCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
STAVAATVAGAPGQGAQLTRAEFEQLISTPLDRFLDWCQEALRRNGIGNSTLRGVAIVGG
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC
GASIPLLTARLSGRFGVPVHSTAQPGLSAALGAATLGAQYASGAAPTAAAAAAVETPTEM
CCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHH
VGAGGLDMTQAAWAAQATDVDDALAWSQDADTSDEPVPYTGRDATGEYASEARRFDDAAA
HCCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GGLPWYKRTALVLSVAGAGAAVLIALVLAINLLLTKSTQDRPTSPPSTPAPPQTVTITGP
CCCCHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECC
NDSTTVTVVPAPPPPSSEAPPPPATTTTAPPEPSTTTTTTTPPPSSTTTTSAAPTTTAQP
CCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
STTSAASTTTRVRPIPPIFQPPFGR
CCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA