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The map label for this gene is atsG

Identifier: 41409889

GI number: 41409889

Start: 4238468

End: 4239898

Strand: Reverse

Name: atsG

Synonym: MAP3791c

Alternate gene names: 41409889

Gene position: 4239898-4238468 (Counterclockwise)

Preceding gene: 41409890

Following gene: 41409887

Centisome position: 87.79

GC content: 68.97

Gene sequence:

>1431_bases
GTGACGCAATTGACGCCGGGCGACGCTGGCGACCGCAACGACGCGGGCCGCAAGGACAACGTGCTGATCGTGCACTGGCA
CGACCTGGGGCGCTACCTGGGCGCCTACGGCCACCGGGATGTGTCCAGCCCGCGCCTGGACCGCCTTGCCGCCGAGGGCA
TCCTGTTCACCCGGGCGCACGCCACCGCGCCGCTGTGCTCGCCGTCGCGGGGATCGCTGTTCACCGGCCGCTATCCGCAG
ACCAACGGACTGATCGGGCTGGCCCACCACGGCTGGGAATACCGCAGCGGGATTCGCACCCTGCCCCAGATACTGTCCGA
AGCGGGTTGGTACTCGGCGCTTTTCGGCATGCAACACGAGACCTCCTACCCGAAGCGGTTGGGGTTCGACGAGTTCGACG
TGTCGAATTCCTACTGCGACTACGTGGCGCAGCGGGCCGACGAGTGGCTGCGGCAGAGCGCTGAAGGTGTTGTGGGGCAA
CCGTTTCTGCTGACCGCCGGCTTCTTCGAGACGCACCGGCCATATCCGGAGGACCGGTACCCGCCGGCGGACAGCGCCGA
GGTGCAACCGCCCGACTACCTCCCGGACACCCCGGAGGTGCGCGGCGACCTGGCCGCCTTCTACGGGGCCATCAGCACGG
CCGACGCCGCGGTGGGCCGGCTGCTGGACACGCTGGCCGACACCGGTTTGGACGCCAGCACCTGGGTGGTGTTCTTCACC
GATCACGGGCCGGCGTTCCCGCGGGCGAAATCCACGCTGTACGACGCCGGCACCGGCATCGGCATGATCGTCCGGCCGCC
CACCGGCCGGGGACTGCCGCCCCGGGTGTACGACGAGTTGTTCAGCGCGGTCGATCTGGTGCCAACCCTGTTGGGGCTGT
TGGGAATCAGCGTGCCGCCCGATGTCGACGGCGTGTCGCACGCGTCCGCGCTGCTGCGGCCGGATCCGGATGCCGCGCCG
GTGCGCGAGCACGTGTACACGATGAAGACCTACCACGACTCGTTCGATCCGATTCGCGCGATTCGCACCAAGGATTACAG
CTACATCGAGAATTACGCGTCGCGGCCGCTGCTGGAACTGCCCTGGGACATCGAGGAGAGCCCGTCCGGGATGGCGGTGG
CGCCGTTGGTCACCGCGCCGCGGCCCGAGCGTGAACTCTACGATCTGCGCGCCGACCCCACCGAAATCACCAACCTGCTG
GCCGGAGATGACGCCGACGCCGACGAGGTCGCCGCCAATCTTGCTGTGCTGCTGCATGATTGGCGTCAGCGCACCGGGGA
CGTGATTCCCTCGGAGTTCGCCGGCACCCGCATCGCGGCGCGCTACACCGAAACGTATCTGCAGATTCACCACGGCGCCC
GGCCGACCGCCCGCTCGGCCATCGCCGCCGACCGGGGCATCGAGGAGGAGGGCAACCCCGCGCAGCGGTAG

Upstream 100 bases:

>100_bases
AAACCGGTGGGCGCAACCGCAGCTGCCCTGACCGGTCGGCGGGGCGGGAGTCGTCGCGGCGTGTTGCGGTATCGTCGCCG
GTCGCAAGGCAATGTGAGAG

Downstream 100 bases:

>100_bases
TTGCGGTCATCGTGACGCGAAGTCGCCGCCCGGGCCGCGCCCAGTGTGGGGCCTACGCACGTGTCCCGTTCGTTTTTCGT
ACCTGCCCCACACGCTCGGC

Product: AtsG

Products: NA

Alternate protein names: Sulfatase AtsG; Arylsulfatase; Arylsulfatase A; Heparan N-Sulfatase; Arylsulphatase A; Sulfatase Family Protein; N-Acetylgalactosamine-6-Sulfate Sulfatase; Choline-Sulfatase; N-Acetylgalactosamine 6-Sulfatase; Iduronate-2-Sulfatase; N-Acetylgalactosamine 6-Sulfate Sulfatase; Twin-Arginine Translocation Pathway Signal; N-Sulphoglucosamine Sulphohydrolase; N-Acetylgalactosamine-6-Sulfatase; Mucin-Desulfating Sulfatase; Type I Phosphodiesterase/Nucleotide Pyrophosphatase Family; N-Acetylglucosamine-6-Sulfatase; Glucosamine-6-Sulfatase; Arylsulfatase A Family Protein; Arylsulfatase B; N-Acetylgalactosamine-4-Sulfatase; Sulfatase Domain Protein; Secreted Sulfatase; Iduronate Sulfatase; N-Sulfoglucosamine Sulfohydrolase

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MTQLTPGDAGDRNDAGRKDNVLIVHWHDLGRYLGAYGHRDVSSPRLDRLAAEGILFTRAHATAPLCSPSRGSLFTGRYPQ
TNGLIGLAHHGWEYRSGIRTLPQILSEAGWYSALFGMQHETSYPKRLGFDEFDVSNSYCDYVAQRADEWLRQSAEGVVGQ
PFLLTAGFFETHRPYPEDRYPPADSAEVQPPDYLPDTPEVRGDLAAFYGAISTADAAVGRLLDTLADTGLDASTWVVFFT
DHGPAFPRAKSTLYDAGTGIGMIVRPPTGRGLPPRVYDELFSAVDLVPTLLGLLGISVPPDVDGVSHASALLRPDPDAAP
VREHVYTMKTYHDSFDPIRAIRTKDYSYIENYASRPLLELPWDIEESPSGMAVAPLVTAPRPERELYDLRADPTEITNLL
AGDDADADEVAANLAVLLHDWRQRTGDVIPSEFAGTRIAARYTETYLQIHHGARPTARSAIAADRGIEEEGNPAQR

Sequences:

>Translated_476_residues
MTQLTPGDAGDRNDAGRKDNVLIVHWHDLGRYLGAYGHRDVSSPRLDRLAAEGILFTRAHATAPLCSPSRGSLFTGRYPQ
TNGLIGLAHHGWEYRSGIRTLPQILSEAGWYSALFGMQHETSYPKRLGFDEFDVSNSYCDYVAQRADEWLRQSAEGVVGQ
PFLLTAGFFETHRPYPEDRYPPADSAEVQPPDYLPDTPEVRGDLAAFYGAISTADAAVGRLLDTLADTGLDASTWVVFFT
DHGPAFPRAKSTLYDAGTGIGMIVRPPTGRGLPPRVYDELFSAVDLVPTLLGLLGISVPPDVDGVSHASALLRPDPDAAP
VREHVYTMKTYHDSFDPIRAIRTKDYSYIENYASRPLLELPWDIEESPSGMAVAPLVTAPRPERELYDLRADPTEITNLL
AGDDADADEVAANLAVLLHDWRQRTGDVIPSEFAGTRIAARYTETYLQIHHGARPTARSAIAADRGIEEEGNPAQR
>Mature_475_residues
TQLTPGDAGDRNDAGRKDNVLIVHWHDLGRYLGAYGHRDVSSPRLDRLAAEGILFTRAHATAPLCSPSRGSLFTGRYPQT
NGLIGLAHHGWEYRSGIRTLPQILSEAGWYSALFGMQHETSYPKRLGFDEFDVSNSYCDYVAQRADEWLRQSAEGVVGQP
FLLTAGFFETHRPYPEDRYPPADSAEVQPPDYLPDTPEVRGDLAAFYGAISTADAAVGRLLDTLADTGLDASTWVVFFTD
HGPAFPRAKSTLYDAGTGIGMIVRPPTGRGLPPRVYDELFSAVDLVPTLLGLLGISVPPDVDGVSHASALLRPDPDAAPV
REHVYTMKTYHDSFDPIRAIRTKDYSYIENYASRPLLELPWDIEESPSGMAVAPLVTAPRPERELYDLRADPTEITNLLA
GDDADADEVAANLAVLLHDWRQRTGDVIPSEFAGTRIAARYTETYLQIHHGARPTARSAIAADRGIEEEGNPAQR

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4506919, Length=460, Percent_Identity=28.2608695652174, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI4557659, Length=412, Percent_Identity=25.7281553398058, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI4503899, Length=347, Percent_Identity=28.8184438040346, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI5360208, Length=315, Percent_Identity=26.031746031746, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI157266309, Length=151, Percent_Identity=31.7880794701987, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI71852586, Length=134, Percent_Identity=32.089552238806, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI71852584, Length=134, Percent_Identity=32.089552238806, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1790112, Length=474, Percent_Identity=23.2067510548523, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790233, Length=471, Percent_Identity=22.9299363057325, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356831, Length=463, Percent_Identity=27.2138228941685, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24666109, Length=369, Percent_Identity=26.0162601626016, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24666175, Length=343, Percent_Identity=25.3644314868805, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24656835, Length=100, Percent_Identity=39, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.6.- [C]

Molecular weight: Translated: 52282; Mature: 52150

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00523 SULFATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLTPGDAGDRNDAGRKDNVLIVHWHDLGRYLGAYGHRDVSSPRLDRLAAEGILFTRAH
CCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEEECC
ATAPLCSPSRGSLFTGRYPQTNGLIGLAHHGWEYRSGIRTLPQILSEAGWYSALFGMQHE
CCCCCCCCCCCCEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
TSYPKRLGFDEFDVSNSYCDYVAQRADEWLRQSAEGVVGQPFLLTAGFFETHRPYPEDRY
CCCHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHCCCCCCCCC
PPADSAEVQPPDYLPDTPEVRGDLAAFYGAISTADAAVGRLLDTLADTGLDASTWVVFFT
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
DHGPAFPRAKSTLYDAGTGIGMIVRPPTGRGLPPRVYDELFSAVDLVPTLLGLLGISVPP
CCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
DVDGVSHASALLRPDPDAAPVREHVYTMKTYHDSFDPIRAIRTKDYSYIENYASRPLLEL
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHCCCCEEC
PWDIEESPSGMAVAPLVTAPRPERELYDLRADPTEITNLLAGDDADADEVAANLAVLLHD
CCCCCCCCCCEEEECEECCCCCCHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHH
WRQRTGDVIPSEFAGTRIAARYTETYLQIHHGARPTARSAIAADRGIEEEGNPAQR
HHHHHCCCCCCHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TQLTPGDAGDRNDAGRKDNVLIVHWHDLGRYLGAYGHRDVSSPRLDRLAAEGILFTRAH
CCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEEECC
ATAPLCSPSRGSLFTGRYPQTNGLIGLAHHGWEYRSGIRTLPQILSEAGWYSALFGMQHE
CCCCCCCCCCCCEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
TSYPKRLGFDEFDVSNSYCDYVAQRADEWLRQSAEGVVGQPFLLTAGFFETHRPYPEDRY
CCCHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHCCCCCCCCC
PPADSAEVQPPDYLPDTPEVRGDLAAFYGAISTADAAVGRLLDTLADTGLDASTWVVFFT
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
DHGPAFPRAKSTLYDAGTGIGMIVRPPTGRGLPPRVYDELFSAVDLVPTLLGLLGISVPP
CCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
DVDGVSHASALLRPDPDAAPVREHVYTMKTYHDSFDPIRAIRTKDYSYIENYASRPLLEL
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHCCCCEEC
PWDIEESPSGMAVAPLVTAPRPERELYDLRADPTEITNLLAGDDADADEVAANLAVLLHD
CCCCCCCCCCEEEECEECCCCCCHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHH
WRQRTGDVIPSEFAGTRIAARYTETYLQIHHGARPTARSAIAADRGIEEEGNPAQR
HHHHHCCCCCCHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Sulfuric ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA