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The map label for this gene is fadE5

Identifier: 41409792

GI number: 41409792

Start: 4109126

End: 4110961

Strand: Reverse

Name: fadE5

Synonym: MAP3694c

Alternate gene names: 41409792

Gene position: 4110961-4109126 (Counterclockwise)

Preceding gene: 41409795

Following gene: 41409790

Centisome position: 85.12

GC content: 66.39

Gene sequence:

>1836_bases
GTGAGCCACTACAAGAGCAACGTCCGCGACCAGGAATTCAACCTGTTCGAAGTGCTGGGCGTTGACAAGGCTTTAGGGCA
AGGCGAGTTCAGCGATCTGGACGCCGACACGGCCCGCGAGATGTTGAACGAAATCAGCCGGCTGGCCGAGGGGCCCATCG
CCGACTCCTTCGTCGAGGGCGACCGCAACCCGCCGGTGTTCGACCCGAAGACGCACTCCGTGACGCTGCCGGAATCGTTC
AAGAAGTCCGTCCACGCCGTCATCGAGGCCGGGTGGGACAAGGTAGGCATCGACGAGGCCCTCGGCGGGGTCGCCATGCC
CAAGGCGCTGCTGTGGGCGCTGCACGAGCACATCCTGGGCGCCAACCCGGCGGTCTGGATGTACGCCGGCGGCGCGGGCT
TCGCCAACATCCTCTACCACCTGGGCACCGACGAGCAGAAGAAGTGGGCCGTGATGGCCGCCGAGCGCGGCTGGGGTTCG
ACCATGGTGCTCACCGAGCCGGACGCGGGTTCCGACGTCGGCGCCGGGCGCACCAAGGCGGTCAAGCAGGACGACGGCTC
CTGGCACATCGACGGTGTGAAGCGATTCATCACCTCGGCCGACTCCGACGACCTGTTCGAGAACATCTTCCACCTGGTGC
TGGCCCGCCCCGAGGGCGCCGGCCCGGGCACCAAGGGCCTGTCGCTGTTCTTCGTGCCCAAGTTCCTGTTCGACTTCGAG
ACCGGTGAGCTCGGCGAGCGCAACGGCGTCTTCGTCACCAATGTCGAGCACAAGATGGGCCTGAAGGTGTCGGCGACCTG
CGAGCTGAGCTTCGGCCAGCACGACGTCCCGGCCAAGGGCTGGCTGGTCGGCGAGGTGCACAACGGGATCGCGCAGATGT
TCGAGGTCATCGAGCAGGCCCGCATGATGGTGGGCACCAAGGCCATCGCGACCCTGTCGACCGGTTACCTGAACGCGTTG
GAGTACGCCAAGTCTCGCGTCCAGGGCGCCGACATGACCCAGATGACCGACAAGACCGCACCGCGGGTGACCATCACGCA
CCACCCGGACGTGCGGCGGTCGCTGATGACCCAGAAGGCCTACGCCGAGGGTCTGCGCGCGCTGTACCTGTTCACCTCGA
CCTACCAGGACGCGGCGGTCGCCGAGGCGCTCTACGGGGTGGACGCCGAACTGGCGGTCAAGGTCAACGACCTGATGCTG
CCGGTGGTCAAGGGCGTCGGCTCCGAGCAGGCCTACGCCAAGCTCACCGAGAGCCTGCAGACCTTCGGTGGCTCCGGCTT
CCTGCAGGACTACCCGATTGAGCAGTACATCCGCGACTCCAAGATCGACTCGCTCTACGAGGGCACCACGGCCATCCAGG
CGCAGGACTTCTTCTTCCGCAAGATCGTCCGCGACAAGGGTGTGGCGCTGGCCCACGTGTCCGAGCAGATCCAGAAGTTC
GTCGACAGCGAGTCCGGCAACGGCCGGCTCAAGTCCGAGCGCGAACTGCTGGCCAAGGCGCTGGCGGACGTGCAGGGCAT
GGCGACCGCGCTGACCGGCTACCTGATGGCCGCCCAGGAGGACGTGACCAGCCTGTACAAGGTGGGCCTGGGTTCGGTGC
GGTTCCTGATGAGCGTCGGTGACCTGATCATCGGCTGGTTGCTGCAGCGTCAGGCGGCGGTGGCCGTGGCGGCGCTGGAC
GCCGGCGCCAGCGGGGAGGACCGGTCCTTCTACGAGGGCAAGATCGCGGTGGCGTCGTTCTTCGCGAAGAACTTCCTGCC
GATGCTGACCAGCACCCGCGAGGTCATCGAGACGCTGGACAACGACATCATGGAGCTCGACGAGGCGGCCTTCTAA

Upstream 100 bases:

>100_bases
TGCATCCCGCTGACGCGAACGATATTTTGAAGTTGTTACTGGTGGGTAACTTAGACCTAGTACCCAACCACAAGTGGCAT
TCTCAACGAGGAGGACCGTA

Downstream 100 bases:

>100_bases
AGCCCTTCCGAGGCCGCTGACAAGCGCAATCAAAAACCCCGCTTCCGGATGGGAGCGGGGTTTTTGATTGCGCGGCGCCG
GATGGGCGCACGATCGGGCG

Product: FadE5

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; BCAD; SCAD [H]

Number of amino acids: Translated: 611; Mature: 610

Protein sequence:

>611_residues
MSHYKSNVRDQEFNLFEVLGVDKALGQGEFSDLDADTAREMLNEISRLAEGPIADSFVEGDRNPPVFDPKTHSVTLPESF
KKSVHAVIEAGWDKVGIDEALGGVAMPKALLWALHEHILGANPAVWMYAGGAGFANILYHLGTDEQKKWAVMAAERGWGS
TMVLTEPDAGSDVGAGRTKAVKQDDGSWHIDGVKRFITSADSDDLFENIFHLVLARPEGAGPGTKGLSLFFVPKFLFDFE
TGELGERNGVFVTNVEHKMGLKVSATCELSFGQHDVPAKGWLVGEVHNGIAQMFEVIEQARMMVGTKAIATLSTGYLNAL
EYAKSRVQGADMTQMTDKTAPRVTITHHPDVRRSLMTQKAYAEGLRALYLFTSTYQDAAVAEALYGVDAELAVKVNDLML
PVVKGVGSEQAYAKLTESLQTFGGSGFLQDYPIEQYIRDSKIDSLYEGTTAIQAQDFFFRKIVRDKGVALAHVSEQIQKF
VDSESGNGRLKSERELLAKALADVQGMATALTGYLMAAQEDVTSLYKVGLGSVRFLMSVGDLIIGWLLQRQAAVAVAALD
AGASGEDRSFYEGKIAVASFFAKNFLPMLTSTREVIETLDNDIMELDEAAF

Sequences:

>Translated_611_residues
MSHYKSNVRDQEFNLFEVLGVDKALGQGEFSDLDADTAREMLNEISRLAEGPIADSFVEGDRNPPVFDPKTHSVTLPESF
KKSVHAVIEAGWDKVGIDEALGGVAMPKALLWALHEHILGANPAVWMYAGGAGFANILYHLGTDEQKKWAVMAAERGWGS
TMVLTEPDAGSDVGAGRTKAVKQDDGSWHIDGVKRFITSADSDDLFENIFHLVLARPEGAGPGTKGLSLFFVPKFLFDFE
TGELGERNGVFVTNVEHKMGLKVSATCELSFGQHDVPAKGWLVGEVHNGIAQMFEVIEQARMMVGTKAIATLSTGYLNAL
EYAKSRVQGADMTQMTDKTAPRVTITHHPDVRRSLMTQKAYAEGLRALYLFTSTYQDAAVAEALYGVDAELAVKVNDLML
PVVKGVGSEQAYAKLTESLQTFGGSGFLQDYPIEQYIRDSKIDSLYEGTTAIQAQDFFFRKIVRDKGVALAHVSEQIQKF
VDSESGNGRLKSERELLAKALADVQGMATALTGYLMAAQEDVTSLYKVGLGSVRFLMSVGDLIIGWLLQRQAAVAVAALD
AGASGEDRSFYEGKIAVASFFAKNFLPMLTSTREVIETLDNDIMELDEAAF
>Mature_610_residues
SHYKSNVRDQEFNLFEVLGVDKALGQGEFSDLDADTAREMLNEISRLAEGPIADSFVEGDRNPPVFDPKTHSVTLPESFK
KSVHAVIEAGWDKVGIDEALGGVAMPKALLWALHEHILGANPAVWMYAGGAGFANILYHLGTDEQKKWAVMAAERGWGST
MVLTEPDAGSDVGAGRTKAVKQDDGSWHIDGVKRFITSADSDDLFENIFHLVLARPEGAGPGTKGLSLFFVPKFLFDFET
GELGERNGVFVTNVEHKMGLKVSATCELSFGQHDVPAKGWLVGEVHNGIAQMFEVIEQARMMVGTKAIATLSTGYLNALE
YAKSRVQGADMTQMTDKTAPRVTITHHPDVRRSLMTQKAYAEGLRALYLFTSTYQDAAVAEALYGVDAELAVKVNDLMLP
VVKGVGSEQAYAKLTESLQTFGGSGFLQDYPIEQYIRDSKIDSLYEGTTAIQAQDFFFRKIVRDKGVALAHVSEQIQKFV
DSESGNGRLKSERELLAKALADVQGMATALTGYLMAAQEDVTSLYKVGLGSVRFLMSVGDLIIGWLLQRQAAVAVAALDA
GASGEDRSFYEGKIAVASFFAKNFLPMLTSTREVIETLDNDIMELDEAAF

Specific function: Has an optimum specificity for 4-carbon length fatty acyl-CoAs [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=424, Percent_Identity=25.9433962264151, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4501857, Length=390, Percent_Identity=25.3846153846154, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI187960098, Length=313, Percent_Identity=27.4760383386581, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI4557231, Length=313, Percent_Identity=27.4760383386581, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI4557233, Length=361, Percent_Identity=26.8698060941828, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4557235, Length=324, Percent_Identity=25.6172839506173, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI76496475, Length=324, Percent_Identity=25.6172839506173, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87082384, Length=317, Percent_Identity=27.7602523659306, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1786223, Length=402, Percent_Identity=26.1194029850746, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17534899, Length=316, Percent_Identity=30.379746835443, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17569725, Length=318, Percent_Identity=29.559748427673, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI86563381, Length=365, Percent_Identity=26.3013698630137, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI86563383, Length=365, Percent_Identity=26.3013698630137, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=438, Percent_Identity=24.4292237442922, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24666513, Length=373, Percent_Identity=26.5415549597855, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24660351, Length=327, Percent_Identity=26.2996941896024, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=27.1276595744681, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281363737, Length=323, Percent_Identity=26.625386996904, Blast_Score=80, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24646207, Length=323, Percent_Identity=24.7678018575851, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 66562; Mature: 66431

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHYKSNVRDQEFNLFEVLGVDKALGQGEFSDLDADTAREMLNEISRLAEGPIADSFVEG
CCCCCCCCCCCCCCHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCC
DRNPPVFDPKTHSVTLPESFKKSVHAVIEAGWDKVGIDEALGGVAMPKALLWALHEHILG
CCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHC
ANPAVWMYAGGAGFANILYHLGTDEQKKWAVMAAERGWGSTMVLTEPDAGSDVGAGRTKA
CCCCEEEEECCCCHHHHHHHCCCCCCHHEEEEEECCCCCCEEEEECCCCCCCCCCCCCCC
VKQDDGSWHIDGVKRFITSADSDDLFENIFHLVLARPEGAGPGTKGLSLFFVPKFLFDFE
EECCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEHEEHHHHHHCCC
TGELGERNGVFVTNVEHKMGLKVSATCELSFGQHDVPAKGWLVGEVHNGIAQMFEVIEQA
CCCCCCCCCEEEEECHHHHCCEEEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHH
RMMVGTKAIATLSTGYLNALEYAKSRVQGADMTQMTDKTAPRVTITHHPDVRRSLMTQKA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHH
YAEGLRALYLFTSTYQDAAVAEALYGVDAELAVKVNDLMLPVVKGVGSEQAYAKLTESLQ
HHHHHHEEHHHHHCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHH
TFGGSGFLQDYPIEQYIRDSKIDSLYEGTTAIQAQDFFFRKIVRDKGVALAHVSEQIQKF
HCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHCCCHHHHHHHHHHHH
VDSESGNGRLKSERELLAKALADVQGMATALTGYLMAAQEDVTSLYKVGLGSVRFLMSVG
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DLIIGWLLQRQAAVAVAALDAGASGEDRSFYEGKIAVASFFAKNFLPMLTSTREVIETLD
HHHHHHHHHHHHHHHHEEECCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NDIMELDEAAF
HHHHHHHHCCC
>Mature Secondary Structure 
SHYKSNVRDQEFNLFEVLGVDKALGQGEFSDLDADTAREMLNEISRLAEGPIADSFVEG
CCCCCCCCCCCCCHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCC
DRNPPVFDPKTHSVTLPESFKKSVHAVIEAGWDKVGIDEALGGVAMPKALLWALHEHILG
CCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHC
ANPAVWMYAGGAGFANILYHLGTDEQKKWAVMAAERGWGSTMVLTEPDAGSDVGAGRTKA
CCCCEEEEECCCCHHHHHHHCCCCCCHHEEEEEECCCCCCEEEEECCCCCCCCCCCCCCC
VKQDDGSWHIDGVKRFITSADSDDLFENIFHLVLARPEGAGPGTKGLSLFFVPKFLFDFE
EECCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEHEEHHHHHHCCC
TGELGERNGVFVTNVEHKMGLKVSATCELSFGQHDVPAKGWLVGEVHNGIAQMFEVIEQA
CCCCCCCCCEEEEECHHHHCCEEEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHH
RMMVGTKAIATLSTGYLNALEYAKSRVQGADMTQMTDKTAPRVTITHHPDVRRSLMTQKA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHH
YAEGLRALYLFTSTYQDAAVAEALYGVDAELAVKVNDLMLPVVKGVGSEQAYAKLTESLQ
HHHHHHEEHHHHHCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHH
TFGGSGFLQDYPIEQYIRDSKIDSLYEGTTAIQAQDFFFRKIVRDKGVALAHVSEQIQKF
HCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHCCCHHHHHHHHHHHH
VDSESGNGRLKSERELLAKALADVQGMATALTGYLMAAQEDVTSLYKVGLGSVRFLMSVG
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DLIIGWLLQRQAAVAVAALDAGASGEDRSFYEGKIAVASFFAKNFLPMLTSTREVIETLD
HHHHHHHHHHHHHHHHEEECCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NDIMELDEAAF
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8399220; 7857927 [H]