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The map label for this gene is yngJ [H]

Identifier: 41408686

GI number: 41408686

Start: 2911750

End: 2912871

Strand: Direct

Name: yngJ [H]

Synonym: MAP2588

Alternate gene names: 41408686

Gene position: 2911750-2912871 (Clockwise)

Preceding gene: 41408685

Following gene: 41408687

Centisome position: 60.29

GC content: 71.39

Gene sequence:

>1122_bases
ATGGACTTCTCGTTCACCGAAGAGCAGGAGACGATCGGCAAGCTGGCCCGCGATCTGTTCGAGCGCCGCGCCACCCCGGA
ACGGCTGACCGAGTTGGAGGTCGGCGACACCCGCCACGACGCCGCGCTCTGGGAAGAGCTGGCCGCCGCCGACCTGCTCG
GTGCCGCGCTGCCGGAGGCGGTCGGAGGCTCATGTGCTTCAGGCGGCGGCTTCGTGGAGCTCGGGGTGCTGCTGGCGGAG
GTGGGCTACGGCGTCGCGCCGGTGCCCGCTTACGCCACGCTGGTGTTGGGCGCCGACTCGATCGCCCGGCACGGCAGCTC
AGAACAGCAGCAGCGGGTCTTGCCGGGCGTGATCGCCGGATCGCGCATCCTGACAGCGGGTTTGGCCGAACCCGGTCGTT
CGGATCCGGCCCGCCCGGCCACCACCGCGCGTCGCGACGGCCCGAACTGGCGCCTCGACGGCGCCAAGGAGTTGGTGCCG
GCCGCCCAACTCGCCGACACGATGCTGATTCCCGCCGTCCTGGACGACGGCGACGTGGGCCTGTTCCTGCTGGCCGCCGA
CGCCGCCGGCGTCGAGATCCGCCCGGTGCCCACCACGAATCGCGAACCGCACGCGGACGTATTCTTAGCCGGCGCACGTG
TTTCCGAGACGGACCGGATCGCCGGCATTGGACTGGTCGAGTCACTGCTCACCCGGGCGCTGGTGGCGCTGTGCGCGATC
CAGCTCGGCGTCGTCGAGCGGGCGCTGCGCATCGCGGCCAAATACACCACGGGCCGTGAGCAATTCGGCCGCCCGATCGG
CAGCTTCCAGGCGGTGCAGCAGCGGATGGCCGACGCCTTCATCGACGTCGAGGCGATCCGGTGGACCACCTGGCAGGCGG
CCTGGCTGGTCGCCCACGGCCGGCCCGCCGACCGGGCGGCGCGCATCGCGAAGTTCTGGGCCGCCGAGGCCGGCGCTCGG
GTGGCCGCCACCGCCCAGCACGTCCACGGCGGCATCGGCATCGACGTCACCTATCCCCTGCACCGCTATTTCCTGTGGGC
CAAGCACAACGAGCTCACCCTCGGTCCGGCTTCGGCGCAGCTGGCCCACCTCGGCGCAACCTATTCGGAAGGACACGCAT
GA

Upstream 100 bases:

>100_bases
GAGGTGACGCCCGGACTGCCGGTCGAGGTCTACTACCAAACCTTCGACGGCTCGCAAAACCTGGTGCTGCACCAGTTCCG
GCCGAGCGCATAGGCCCGTC

Downstream 100 bases:

>100_bases
CGAGGACCGCCAACCGCACGTTGCGATGGCAGGACATTTCGGTCGGCGAGGAGGTCACGCCGCTGGAAATCCCGATCACC
ACGACGATGATCGTTGCCGG

Product: hypothetical protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MDFSFTEEQETIGKLARDLFERRATPERLTELEVGDTRHDAALWEELAAADLLGAALPEAVGGSCASGGGFVELGVLLAE
VGYGVAPVPAYATLVLGADSIARHGSSEQQQRVLPGVIAGSRILTAGLAEPGRSDPARPATTARRDGPNWRLDGAKELVP
AAQLADTMLIPAVLDDGDVGLFLLAADAAGVEIRPVPTTNREPHADVFLAGARVSETDRIAGIGLVESLLTRALVALCAI
QLGVVERALRIAAKYTTGREQFGRPIGSFQAVQQRMADAFIDVEAIRWTTWQAAWLVAHGRPADRAARIAKFWAAEAGAR
VAATAQHVHGGIGIDVTYPLHRYFLWAKHNELTLGPASAQLAHLGATYSEGHA

Sequences:

>Translated_373_residues
MDFSFTEEQETIGKLARDLFERRATPERLTELEVGDTRHDAALWEELAAADLLGAALPEAVGGSCASGGGFVELGVLLAE
VGYGVAPVPAYATLVLGADSIARHGSSEQQQRVLPGVIAGSRILTAGLAEPGRSDPARPATTARRDGPNWRLDGAKELVP
AAQLADTMLIPAVLDDGDVGLFLLAADAAGVEIRPVPTTNREPHADVFLAGARVSETDRIAGIGLVESLLTRALVALCAI
QLGVVERALRIAAKYTTGREQFGRPIGSFQAVQQRMADAFIDVEAIRWTTWQAAWLVAHGRPADRAARIAKFWAAEAGAR
VAATAQHVHGGIGIDVTYPLHRYFLWAKHNELTLGPASAQLAHLGATYSEGHA
>Mature_373_residues
MDFSFTEEQETIGKLARDLFERRATPERLTELEVGDTRHDAALWEELAAADLLGAALPEAVGGSCASGGGFVELGVLLAE
VGYGVAPVPAYATLVLGADSIARHGSSEQQQRVLPGVIAGSRILTAGLAEPGRSDPARPATTARRDGPNWRLDGAKELVP
AAQLADTMLIPAVLDDGDVGLFLLAADAAGVEIRPVPTTNREPHADVFLAGARVSETDRIAGIGLVESLLTRALVALCAI
QLGVVERALRIAAKYTTGREQFGRPIGSFQAVQQRMADAFIDVEAIRWTTWQAAWLVAHGRPADRAARIAKFWAAEAGAR
VAATAQHVHGGIGIDVTYPLHRYFLWAKHNELTLGPASAQLAHLGATYSEGHA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=372, Percent_Identity=25.5376344086022, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI4501857, Length=361, Percent_Identity=23.5457063711911, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI4501859, Length=383, Percent_Identity=25.065274151436, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI4557231, Length=383, Percent_Identity=25.3263707571802, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI187960098, Length=383, Percent_Identity=25.3263707571802, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4503943, Length=352, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI7669494, Length=352, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI21361497, Length=327, Percent_Identity=25.0764525993884, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1786223, Length=380, Percent_Identity=25, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87081958, Length=349, Percent_Identity=26.3610315186246, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17534353, Length=368, Percent_Identity=25.5434782608696, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17508101, Length=324, Percent_Identity=24.0740740740741, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17506239, Length=330, Percent_Identity=24.2424242424242, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17538396, Length=328, Percent_Identity=25, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17534899, Length=351, Percent_Identity=26.2108262108262, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=400, Percent_Identity=24.25, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24646207, Length=327, Percent_Identity=27.5229357798165, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI19920834, Length=301, Percent_Identity=30.2325581395349, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24666513, Length=382, Percent_Identity=24.6073298429319, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356377, Length=325, Percent_Identity=23.6923076923077, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24660351, Length=392, Percent_Identity=23.9795918367347, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 39519; Mature: 39519

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSFTEEQETIGKLARDLFERRATPERLTELEVGDTRHDAALWEELAAADLLGAALPEA
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VGGSCASGGGFVELGVLLAEVGYGVAPVPAYATLVLGADSIARHGSSEQQQRVLPGVIAG
HCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHCCCCHHHHHHCCHHHHC
SRILTAGLAEPGRSDPARPATTARRDGPNWRLDGAKELVPAAQLADTMLIPAVLDDGDVG
CHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCE
LFLLAADAAGVEIRPVPTTNREPHADVFLAGARVSETDRIAGIGLVESLLTRALVALCAI
EEEEEECCCCEEEEECCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QLGVVERALRIAAKYTTGREQFGRPIGSFQAVQQRMADAFIDVEAIRWTTWQAAWLVAHG
HHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEECEEEEEEEECC
RPADRAARIAKFWAAEAGARVAATAQHVHGGIGIDVTYPLHRYFLWAKHNELTLGPASAQ
CCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEECHHHHEEEEEECCCEEECCCHHH
LAHLGATYSEGHA
HHHHCCCCCCCCC
>Mature Secondary Structure
MDFSFTEEQETIGKLARDLFERRATPERLTELEVGDTRHDAALWEELAAADLLGAALPEA
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VGGSCASGGGFVELGVLLAEVGYGVAPVPAYATLVLGADSIARHGSSEQQQRVLPGVIAG
HCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHCCCCHHHHHHCCHHHHC
SRILTAGLAEPGRSDPARPATTARRDGPNWRLDGAKELVPAAQLADTMLIPAVLDDGDVG
CHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCE
LFLLAADAAGVEIRPVPTTNREPHADVFLAGARVSETDRIAGIGLVESLLTRALVALCAI
EEEEEECCCCEEEEECCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QLGVVERALRIAAKYTTGREQFGRPIGSFQAVQQRMADAFIDVEAIRWTTWQAAWLVAHG
HHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEECEEEEEEEECC
RPADRAARIAKFWAAEAGARVAATAQHVHGGIGIDVTYPLHRYFLWAKHNELTLGPASAQ
CCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEECHHHHEEEEEECCCEEECCCHHH
LAHLGATYSEGHA
HHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]