| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is kduD [C]
Identifier: 41408626
GI number: 41408626
Start: 2840176
End: 2841024
Strand: Direct
Name: kduD [C]
Synonym: MAP2528
Alternate gene names: 41408626
Gene position: 2840176-2841024 (Clockwise)
Preceding gene: 41408620
Following gene: 41408627
Centisome position: 58.81
GC content: 65.02
Gene sequence:
>849_bases ATGGACGTCCCAATGGCAGGAAAGGTCGAGGGCAAGGTGGCCTTCATCACCGGTGCGGCGCGCGGGCAGGGGCGCAGCCA CGCCATAACGCTCGCGCGTGAGGGCGCCGACATCATCGCCATCGATGTGTGCAAGCAGCTCGACGGAGTCAAACTCCCGA TGTCCACGCCCGACGACCTGGCGGAGACCGTGCGCCAGGTCGAGGCGCTCGGACGGCGGATCATCGCGTCGCAGGTCGAT GTTCGAGACTTCGACGCCATGCAGGCCGCGGTCGACGACGGTGTCACACAGCTCGGGCGCCTGGACATCGTGCTCGCCAA TGCCGCCCTCGCCAGTGAGGGCACGCGGCTGAACCGGATGGGCCCGAAGACGTGGCGCGACATGATCGACGTCAACCTCA ACGGCGCGTGGATCACCGCGCGGGTGGCGATACCTCACATCATGGCCGGTAAGCGCGGCGGCTCGATCGTGTTCACCAGC TCCATCGGCGGCCTCCGCGGCGCCGAGAACATCGGCAACTACATCGCGTCCAAACACGGGCTGCACGGGTTGATGCGCAC CATGGCCCTGGAACTCGGTCCAAGAAACATCCGCGTCAACATCGTGTGCCCGAGCAGCGTCGCCACACCCATGCTGCTCA ACGAGCCGACCTACCGGATGTTTCGGCCCGACTTGGAAAATCCCACCGTGGAGGACTTCAAGGTCGCGTCACGGCAGATG CACGTGCTTCCGATTCCGTACGTCGAACCTGCCGACATCAGCAACGCCATCCTCTTTCTGGTCTCAGACGACGCGCGCTA CATCACCGGGGTCGCACTACCGGTCGACGGCGGCGCCCTCCTCAAATAA
Upstream 100 bases:
>100_bases GATGGTTTAAGCATTTTCACATGCCGACGACCGCTGTACGGGTGTATTGTACCGTTCTAGTAACCTGTACGTTCGTATAG CGGATGTAATCACGAAGGGA
Downstream 100 bases:
>100_bases GCAGCCGTACAACACAACTCGAAAGGATCAGCTTCCATGTCACGCGTGACACCACTTCGTTTCCGGGACTGGCCGCCGGA GATGCGCGACGCGATGGCCG
Product: hypothetical protein
Products: @DEHY06.txt*3-Dehydro-2- Deoxy-D-Gluconate!; NADH. [C]
Alternate protein names: NA
Number of amino acids: Translated: 282; Mature: 282
Protein sequence:
>282_residues MDVPMAGKVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQVEALGRRIIASQVD VRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMGPKTWRDMIDVNLNGAWITARVAIPHIMAGKRGGSIVFTS SIGGLRGAENIGNYIASKHGLHGLMRTMALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFKVASRQM HVLPIPYVEPADISNAILFLVSDDARYITGVALPVDGGALLK
Sequences:
>Translated_282_residues MDVPMAGKVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQVEALGRRIIASQVD VRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMGPKTWRDMIDVNLNGAWITARVAIPHIMAGKRGGSIVFTS SIGGLRGAENIGNYIASKHGLHGLMRTMALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFKVASRQM HVLPIPYVEPADISNAILFLVSDDARYITGVALPVDGGALLK >Mature_282_residues MDVPMAGKVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQVEALGRRIIASQVD VRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMGPKTWRDMIDVNLNGAWITARVAIPHIMAGKRGGSIVFTS SIGGLRGAENIGNYIASKHGLHGLMRTMALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFKVASRQM HVLPIPYVEPADISNAILFLVSDDARYITGVALPVDGGALLK
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=289, Percent_Identity=29.0657439446367, Blast_Score=103, Evalue=3e-22, Organism=Homo sapiens, GI32483357, Length=267, Percent_Identity=27.7153558052434, Blast_Score=95, Evalue=8e-20, Organism=Homo sapiens, GI4504505, Length=225, Percent_Identity=28.4444444444444, Blast_Score=88, Evalue=1e-17, Organism=Homo sapiens, GI10190704, Length=270, Percent_Identity=28.8888888888889, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI40254992, Length=270, Percent_Identity=30.3703703703704, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI7705925, Length=269, Percent_Identity=29.7397769516729, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI66933014, Length=272, Percent_Identity=25, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI31542939, Length=264, Percent_Identity=28.7878787878788, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI59889578, Length=204, Percent_Identity=28.4313725490196, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI126723750, Length=270, Percent_Identity=25.5555555555556, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI19923817, Length=277, Percent_Identity=23.826714801444, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI4503301, Length=272, Percent_Identity=26.1029411764706, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI4758504, Length=220, Percent_Identity=29.0909090909091, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI40254986, Length=153, Percent_Identity=30.0653594771242, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI5031737, Length=276, Percent_Identity=25, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI126723191, Length=191, Percent_Identity=27.2251308900524, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI1789208, Length=277, Percent_Identity=30.6859205776173, Blast_Score=129, Evalue=3e-31, Organism=Escherichia coli, GI87082100, Length=276, Percent_Identity=30.7971014492754, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI1788459, Length=270, Percent_Identity=29.6296296296296, Blast_Score=104, Evalue=7e-24, Organism=Escherichia coli, GI1787335, Length=269, Percent_Identity=30.4832713754647, Blast_Score=103, Evalue=8e-24, Organism=Escherichia coli, GI87082160, Length=277, Percent_Identity=29.6028880866426, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1787905, Length=275, Percent_Identity=28, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1787526, Length=275, Percent_Identity=28.7272727272727, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1790717, Length=272, Percent_Identity=25.3676470588235, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1789378, Length=277, Percent_Identity=25.9927797833935, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI1786812, Length=275, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1788891, Length=215, Percent_Identity=28.3720930232558, Blast_Score=72, Evalue=5e-14, Organism=Escherichia coli, GI2367175, Length=276, Percent_Identity=26.4492753623188, Blast_Score=65, Evalue=5e-12, Organism=Caenorhabditis elegans, GI71994604, Length=270, Percent_Identity=29.2592592592593, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17560676, Length=280, Percent_Identity=27.1428571428571, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI71994600, Length=278, Percent_Identity=28.7769784172662, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17555706, Length=270, Percent_Identity=30.7407407407407, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17568967, Length=228, Percent_Identity=29.3859649122807, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI25147288, Length=276, Percent_Identity=27.8985507246377, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI193203117, Length=207, Percent_Identity=28.0193236714976, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI193203115, Length=206, Percent_Identity=27.6699029126214, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17561402, Length=272, Percent_Identity=25, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17567345, Length=237, Percent_Identity=30.379746835443, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562904, Length=284, Percent_Identity=28.5211267605634, Blast_Score=82, Evalue=5e-16, Organism=Caenorhabditis elegans, GI115534694, Length=268, Percent_Identity=28.3582089552239, Blast_Score=81, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17560150, Length=281, Percent_Identity=27.0462633451957, Blast_Score=80, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17564282, Length=207, Percent_Identity=29.4685990338164, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17562910, Length=284, Percent_Identity=28.169014084507, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17531453, Length=282, Percent_Identity=30.1418439716312, Blast_Score=79, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17559104, Length=283, Percent_Identity=27.9151943462898, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17562990, Length=281, Percent_Identity=26.6903914590747, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17544670, Length=288, Percent_Identity=25.6944444444444, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17562908, Length=290, Percent_Identity=26.551724137931, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI71982365, Length=203, Percent_Identity=27.0935960591133, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17562906, Length=283, Percent_Identity=27.208480565371, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI71997099, Length=236, Percent_Identity=28.8135593220339, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17565030, Length=286, Percent_Identity=27.6223776223776, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17538480, Length=292, Percent_Identity=27.3972602739726, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17538486, Length=281, Percent_Identity=27.4021352313167, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17560220, Length=286, Percent_Identity=26.2237762237762, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=271, Percent_Identity=26.1992619926199, Blast_Score=92, Evalue=8e-20, Organism=Saccharomyces cerevisiae, GI6322861, Length=197, Percent_Identity=27.9187817258883, Blast_Score=84, Evalue=3e-17, Organism=Drosophila melanogaster, GI24644339, Length=273, Percent_Identity=30.03663003663, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI24639444, Length=276, Percent_Identity=28.6231884057971, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI21355319, Length=271, Percent_Identity=26.5682656826568, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI28571526, Length=272, Percent_Identity=28.3088235294118, Blast_Score=91, Evalue=7e-19, Organism=Drosophila melanogaster, GI21357041, Length=268, Percent_Identity=28.3582089552239, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI18859837, Length=225, Percent_Identity=28, Blast_Score=87, Evalue=9e-18, Organism=Drosophila melanogaster, GI23397609, Length=273, Percent_Identity=26.3736263736264, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI24644337, Length=184, Percent_Identity=32.6086956521739, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24643142, Length=278, Percent_Identity=26.2589928057554, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI24649181, Length=205, Percent_Identity=28.2926829268293, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI21357673, Length=201, Percent_Identity=27.363184079602, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI17737361, Length=219, Percent_Identity=28.310502283105, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI24580925, Length=211, Percent_Identity=24.1706161137441, Blast_Score=64, Evalue=1e-10,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.125 [C]
Molecular weight: Translated: 30259; Mature: 30259
Theoretical pI: Translated: 7.06; Mature: 7.06
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 4.3 %Met (Translated Protein) 5.0 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 4.3 %Met (Mature Protein) 5.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDVPMAGKVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDL CCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCEEEEEEHHHCCCEECCCCCHHHH AETVRQVEALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRM HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCHHHCCCCCCCCC GPKTWRDMIDVNLNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHG CCHHHHHHEEECCCCEEEEEEEECCHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH LHGLMRTMALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFKVASRQM HHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEECCCCHHHCCCCCCCCCHHHHHHHCCCE HVLPIPYVEPADISNAILFLVSDDARYITGVALPVDGGALLK EEEECCCCCCCCCCCEEEEEEECCCEEEEEEEEECCCCCCCC >Mature Secondary Structure MDVPMAGKVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDL CCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCEEEEEEHHHCCCEECCCCCHHHH AETVRQVEALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRM HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCHHHCCCCCCCCC GPKTWRDMIDVNLNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHG CCHHHHHHEEECCCCEEEEEEEECCHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH LHGLMRTMALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFKVASRQM HHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEECCCCHHHCCCCCCCCCHHHHHHHCCCE HVLPIPYVEPADISNAILFLVSDDARYITGVALPVDGGALLK EEEECCCCCCCCCCCEEEEEEECCCEEEEEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NAD+ [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 15.4 {2-deoxygluconate}} [C]
Substrates: @DEOX03.txt*2-Deoxy-D-Gluconate!; NAD(+) [C]
Specific reaction: @DEOX03.txt*2-Deoxy-D-Gluconate! + NAD(+) = @DEHY06.txt*3-Dehydro-2- Deoxy-D-Gluconate! + NADH. [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA