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The map label for this gene is 41408546

Identifier: 41408546

GI number: 41408546

Start: 2754503

End: 2755102

Strand: Direct

Name: 41408546

Synonym: MAP2448

Alternate gene names: NA

Gene position: 2754503-2755102 (Clockwise)

Preceding gene: 41408543

Following gene: 41408569

Centisome position: 57.03

GC content: 68.67

Gene sequence:

>600_bases
TTGGTCATGGCAGTGCATCTGACGCGCATCTACACGCGGACCGGCGACGACGGCACCACCGGATTGAGCGACTTCTCCCG
GGTCTCGAAGAACGATCCGCGCCTGGTGGCCTACGCCGACTGTGACGAGGCGAACGCGGCGATCGGCGTGGCGGTGGCGG
TCGGCCGGCCCGGCCCGGAGCTGGCCGGCGTGTTGCGACAGATCCAGAACGACCTGTTCGACGCGGGCGCGGACCTGTCG
ACACCGGTGGTGGAGGACCCCGAGTACCCCCCGCTGCGGGTCACCCAGCCCTACATCGATCGGCTCGAAAAATGGTGTGA
CACATACAACGAGTCGCTGCCGAAGTTGAATTCCTTTGTGCTGCCCGGTGGTTCGCCGCTCTCGGCGCTGTTGCACGTCG
CCCGCACGGTGGTGCGCCGCGCCGAACGCTCGGCGTGGGCCGCGGTGGACGCCGCTCCCGAGGGGGTCAGCGCGCTGCCC
GCGAAGTACCTCAACCGGCTCTCGGACCTGTTGTTCATCCTGTCCCGGGTGGCCAACCCGGACGGTGACGTGCTGTGGAA
ACCGGGCGGTCAACAAGGCGGCGAGCCCGCTCCCGGCTAG

Upstream 100 bases:

>100_bases
TCACCACGAATCGCTCGGCCACCCGGGTCAGTCTAGTGAAGCGGTGTCGGCTTTGTCAGTCAGCCAAGGCTCGGTCCCGC
CCGGGCGCCGCAGTACCGTT

Downstream 100 bases:

>100_bases
AGGCTGCGGCGACGTGACCGGGGCGACGGACGCGACTCCAGCCAGGACAAAAACGCCGTCAACGCGCCCTTGTCGAACGC
GATCTCGTAGCCGGACCTGC

Product: hypothetical protein

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MVMAVHLTRIYTRTGDDGTTGLSDFSRVSKNDPRLVAYADCDEANAAIGVAVAVGRPGPELAGVLRQIQNDLFDAGADLS
TPVVEDPEYPPLRVTQPYIDRLEKWCDTYNESLPKLNSFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAAPEGVSALP
AKYLNRLSDLLFILSRVANPDGDVLWKPGGQQGGEPAPG

Sequences:

>Translated_199_residues
MVMAVHLTRIYTRTGDDGTTGLSDFSRVSKNDPRLVAYADCDEANAAIGVAVAVGRPGPELAGVLRQIQNDLFDAGADLS
TPVVEDPEYPPLRVTQPYIDRLEKWCDTYNESLPKLNSFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAAPEGVSALP
AKYLNRLSDLLFILSRVANPDGDVLWKPGGQQGGEPAPG
>Mature_199_residues
MVMAVHLTRIYTRTGDDGTTGLSDFSRVSKNDPRLVAYADCDEANAAIGVAVAVGRPGPELAGVLRQIQNDLFDAGADLS
TPVVEDPEYPPLRVTQPYIDRLEKWCDTYNESLPKLNSFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAAPEGVSALP
AKYLNRLSDLLFILSRVANPDGDVLWKPGGQQGGEPAPG

Specific function: Unknown

COG id: COG2096

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI16418349, Length=175, Percent_Identity=40, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI115534154, Length=170, Percent_Identity=33.5294117647059, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017858
- InterPro:   IPR002779
- InterPro:   IPR016030
- ProDom:   PD007457 [H]

Pfam domain/function: PF01923 Cob_adeno_trans [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 21307; Mature: 21307

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMAVHLTRIYTRTGDDGTTGLSDFSRVSKNDPRLVAYADCDEANAAIGVAVAVGRPGPE
CEEEEEEHHHHHCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEEECCCCHH
LAGVLRQIQNDLFDAGADLSTPVVEDPEYPPLRVTQPYIDRLEKWCDTYNESLPKLNSFV
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCEE
LPGGSPLSALLHVARTVVRRAERSAWAAVDAAPEGVSALPAKYLNRLSDLLFILSRVANP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DGDVLWKPGGQQGGEPAPG
CCCEEECCCCCCCCCCCCC
>Mature Secondary Structure
MVMAVHLTRIYTRTGDDGTTGLSDFSRVSKNDPRLVAYADCDEANAAIGVAVAVGRPGPE
CEEEEEEHHHHHCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEEECCCCHH
LAGVLRQIQNDLFDAGADLSTPVVEDPEYPPLRVTQPYIDRLEKWCDTYNESLPKLNSFV
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCEE
LPGGSPLSALLHVARTVVRRAERSAWAAVDAAPEGVSALPAKYLNRLSDLLFILSRVANP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DGDVLWKPGGQQGGEPAPG
CCCEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]