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The map label for this gene is kshA [H]

Identifier: 41408475

GI number: 41408475

Start: 2671997

End: 2673010

Strand: Direct

Name: kshA [H]

Synonym: MAP2377

Alternate gene names: 41408475

Gene position: 2671997-2673010 (Clockwise)

Preceding gene: 41408470

Following gene: 41408476

Centisome position: 55.32

GC content: 65.88

Gene sequence:

>1014_bases
GTGAAAGTCCCCTTCACCTGGAAGGTCACCGGCTGGTTCATGGTCGGCTGGTCACCGGAGTTCCCCATCGGAGAGGTGCG
CCCGTTGCACTATTTCGGCGAGGACCTGGTGGCCTACCGCGACGAGTCCGGCGAACTGCACATCTTGGAGGCGCACTGCA
AACACCTGGGCGCCCATCTCGGGCACGGTGGCACGGTGGTCGGCGACTGCGTGCAGTGCCCCTTCCACGGCTGGCGCTGG
GGGCCCGACGGCACCAACCGCTACATCCCCTACCAACCCGATCGGCCCAACCGCGGGTTGCGGCTGAAGGTGTACCCGGT
GCGCGAGCAGTACGACTGCGTGTTCGTCTGGCACCAGCCGCACGGCAAGGAGCCGCAGTGGGAGATGCCGGACATCTTCG
GTAAGTTCCCGCAATTCGAGACCGACCCGGCGGCCTACTACCGGGCCTACCCCGAGTTTTCCCGGCGCGCCGAGCGTGAG
CCGGTGCATCCGCAGATCGTGGCCGAAAACGCGCCCGACAGCGCCCATTTCGAGTACGTGCACCACGCCACGGTGACGCC
GCGGGTGCTGGACTGGAAGATCGTCGAGCAGGAATGGCAGTTCGTCGCCGGCTGGCCCGATGCCAACAGCGACGACCCCG
CGGCCCTCGCGCTGCGCTTCCACAGCCACCTGTTCGGCCTGGGCGGGGCGATCAGCGTCTTCGAAGGCGCGCAGAACCAT
CGGCTGATCTTCACCTGCACACCGGTCGACGACGAGTGCTCGGACCTGTTCTATTCGATCTGGTGGCCCCGCGTCCCCGG
CGACACCGCCGACGTGCCCGAGGGCAAGCTGCGCGAGGTCATCGAAAAGCAGTTCCTGTCCACCGTCTTCGACGATCTGC
AGATCTGGCGCTACCAGAAATACGTCGAGCACCCGCCGTTGTCCAAGGTCGACGCCAAAGGCTATATGGCACTGCGCAAA
TGGGCCACCCAATTCTATGAGCTGCCGCCGGCCGGAACGTCGTCACCGGCATGA

Upstream 100 bases:

>100_bases
GGTCAGCCGCTGTCGTCATGTCACTCCTTGCCGCGCGACGGCCGGACTGCTGAAATCTATACTGTAATGGACTTAGTATC
AACGTATCGGAGGCGCTGGC

Downstream 100 bases:

>100_bases
CGGACCTGGCAGAGCTGGTGGCGCCGGCGCACACCGCCGTCATCACGCAAGAAGTCCAGGGTGCGGTCGTCGGTCCCGAC
GCCGGCCTGGGCGCGCTGGC

Product: hypothetical protein

Products: NA

Alternate protein names: Rieske-type oxygenase; RO [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKVPFTWKVTGWFMVGWSPEFPIGEVRPLHYFGEDLVAYRDESGELHILEAHCKHLGAHLGHGGTVVGDCVQCPFHGWRW
GPDGTNRYIPYQPDRPNRGLRLKVYPVREQYDCVFVWHQPHGKEPQWEMPDIFGKFPQFETDPAAYYRAYPEFSRRAERE
PVHPQIVAENAPDSAHFEYVHHATVTPRVLDWKIVEQEWQFVAGWPDANSDDPAALALRFHSHLFGLGGAISVFEGAQNH
RLIFTCTPVDDECSDLFYSIWWPRVPGDTADVPEGKLREVIEKQFLSTVFDDLQIWRYQKYVEHPPLSKVDAKGYMALRK
WATQFYELPPAGTSSPA

Sequences:

>Translated_337_residues
MKVPFTWKVTGWFMVGWSPEFPIGEVRPLHYFGEDLVAYRDESGELHILEAHCKHLGAHLGHGGTVVGDCVQCPFHGWRW
GPDGTNRYIPYQPDRPNRGLRLKVYPVREQYDCVFVWHQPHGKEPQWEMPDIFGKFPQFETDPAAYYRAYPEFSRRAERE
PVHPQIVAENAPDSAHFEYVHHATVTPRVLDWKIVEQEWQFVAGWPDANSDDPAALALRFHSHLFGLGGAISVFEGAQNH
RLIFTCTPVDDECSDLFYSIWWPRVPGDTADVPEGKLREVIEKQFLSTVFDDLQIWRYQKYVEHPPLSKVDAKGYMALRK
WATQFYELPPAGTSSPA
>Mature_337_residues
MKVPFTWKVTGWFMVGWSPEFPIGEVRPLHYFGEDLVAYRDESGELHILEAHCKHLGAHLGHGGTVVGDCVQCPFHGWRW
GPDGTNRYIPYQPDRPNRGLRLKVYPVREQYDCVFVWHQPHGKEPQWEMPDIFGKFPQFETDPAAYYRAYPEFSRRAERE
PVHPQIVAENAPDSAHFEYVHHATVTPRVLDWKIVEQEWQFVAGWPDANSDDPAALALRFHSHLFGLGGAISVFEGAQNH
RLIFTCTPVDDECSDLFYSIWWPRVPGDTADVPEGKLREVIEKQFLSTVFDDLQIWRYQKYVEHPPLSKVDAKGYMALRK
WATQFYELPPAGTSSPA

Specific function: Catalyzes the opening of ring B of 1,4-androstadiene- 3,17,-dione (ADD) and 4-androstene-3,17-dione (ADD) with concomitant aromatization of ring A. The ring B is subsequently hydroxylated to yield a catechol and then subject to meta- cleavage [H]

COG id: COG4638

COG function: function code PR; Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Rieske domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71983709, Length=348, Percent_Identity=25.2873563218391, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI161085896, Length=343, Percent_Identity=28.8629737609329, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017941 [H]

Pfam domain/function: PF00355 Rieske [H]

EC number: NA

Molecular weight: Translated: 38892; Mature: 38892

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVPFTWKVTGWFMVGWSPEFPIGEVRPLHYFGEDLVAYRDESGELHILEAHCKHLGAHL
CCCCEEEEEEEEEEEECCCCCCCCCCCCHHHHCCCCEEEECCCCCEEEEHHHHHHHHHHC
GHGGTVVGDCVQCPFHGWRWGPDGTNRYIPYQPDRPNRGLRLKVYPVREQYDCVFVWHQP
CCCCCEEHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEECC
HGKEPQWEMPDIFGKFPQFETDPAAYYRAYPEFSRRAEREPVHPQIVAENAPDSAHFEYV
CCCCCCCCCHHHHHCCCCCCCCHHHHHHCCHHHHHHHCCCCCCCEEEECCCCCCCCEEEE
HHATVTPRVLDWKIVEQEWQFVAGWPDANSDDPAALALRFHSHLFGLGGAISVFEGAQNH
EECCCCCEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCC
RLIFTCTPVDDECSDLFYSIWWPRVPGDTADVPEGKLREVIEKQFLSTVFDDLQIWRYQK
EEEEEECCCCCHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YVEHPPLSKVDAKGYMALRKWATQFYELPPAGTSSPA
HHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKVPFTWKVTGWFMVGWSPEFPIGEVRPLHYFGEDLVAYRDESGELHILEAHCKHLGAHL
CCCCEEEEEEEEEEEECCCCCCCCCCCCHHHHCCCCEEEECCCCCEEEEHHHHHHHHHHC
GHGGTVVGDCVQCPFHGWRWGPDGTNRYIPYQPDRPNRGLRLKVYPVREQYDCVFVWHQP
CCCCCEEHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEECC
HGKEPQWEMPDIFGKFPQFETDPAAYYRAYPEFSRRAEREPVHPQIVAENAPDSAHFEYV
CCCCCCCCCHHHHHCCCCCCCCHHHHHHCCHHHHHHHCCCCCCCEEEECCCCCCCCEEEE
HHATVTPRVLDWKIVEQEWQFVAGWPDANSDDPAALALRFHSHLFGLGGAISVFEGAQNH
EECCCCCEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCC
RLIFTCTPVDDECSDLFYSIWWPRVPGDTADVPEGKLREVIEKQFLSTVFDDLQIWRYQK
EEEEEECCCCCHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YVEHPPLSKVDAKGYMALRKWATQFYELPPAGTSSPA
HHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA