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The map label for this gene is kshA [H]

Identifier: 41407532

GI number: 41407532

Start: 1567583

End: 1568701

Strand: Direct

Name: kshA [H]

Synonym: MAP1434

Alternate gene names: 41407532

Gene position: 1567583-1568701 (Clockwise)

Preceding gene: 41407530

Following gene: 41407533

Centisome position: 32.46

GC content: 64.08

Gene sequence:

>1119_bases
GTGCGCATGCATGACACCGACGAAATCCGGCTCATCGAGGCCCAGGCCGTCCCGACCCGGTTTGCCCGCGGCTGGCATTG
CCTGGGCCTGATCCGGGATTTCGGTGACGGCAAGCCGCACCCGATCGACGCCTTCGGGCAGAAACTGGTCGTCTTCCGCG
GCGGCGACGGCGCCATCAACGTGCTCGACGGCTATTGCCGGCACATGGGCGGCGACCTGTCCAGGGGTGAGGTGAAGGGC
AACGAGATCGCCTGCCCCTTCCACGATTGGCGCTGGGGCGGCGACGGCCGGTGCAAGCAGGTGCCCTACAGCCGGCGCAC
GCCCCGGCTGGCCCGCACCCGGGCCTGGACCACCCTGCAGCAGGACGGCATGTTGTTCGTGTGGAACGACCCGGAGGGCA
ATCCGCCGCCGCCGGAGGTAACGATCCCGCGCATCGAGGGTGCCGGCAGCGACGAATGGACCGACTGGCATTGGTATAGC
ACTGTCGTGCAAAGCAATTGCCGCGAGATCATCGACAACGTCGTGGACATGGCGCACTTCTTCTACATCCACGGGTCGCT
TCCCAAGCAGTTCAAGAACATCTTCGAAGGCCACGTGGCCACCCAATACATGAACAGCGCCGGGCGCCCCGATATCGGCG
GTGAGGGCGCGAGGATGCTCGGCACCACTTCGGTGGCCTCCTATTGGGGACCGTCGTTCATGATCGACGACCTGACCTAT
CACTACGAGGACGCCGACCACCAAACGGTGCTGATCAATTGTCACTACCCGATCGACGCGAATTCTTTTGTGCTGCAATA
CGGCATCATCGTCAAGAAATCGGATGCGCTGCCCGACGACCTGGCCATGCAGACCGCGATCGCGCTCGGCGACTTCGTCA
AGCTCGGCTTCGAGCAGGACGTCGAGATCTGGCGGCACAAGGCGCGCATCGACAACCCGCTGCTGGTCGAGGAAGACGGG
CCGGTGTATCAGCTGCGCCGCTGGTATCAGCAGTTCTACGTCGACGTCGCCGACGTGCAACCCGACATGGTGGACCGCTT
CGAATTCGAGCTGGACACCACCCGACCCTACGCCGCATGGATGAAAGAGGTCGAGGCCAACTTGGCGGCCAGGGCCTGA

Upstream 100 bases:

>100_bases
GTCACAGCGAAAACGGTATGTCGCGCCACCGTGATACCGGAATAGCCGTCCTGATGAGTGGAACAGACACCCCCACGGGC
GGGTCCGGCTGCGTTGAATC

Downstream 100 bases:

>100_bases
CGATGCTGAAAATGCCTGTGTGCGAGGATGTTCGGCTCGTCGACATGCCCATGGCGCCGGTGATGTGCCAAGACTGCGGA
GCACGGGTCATGGCCCGCAA

Product: hypothetical protein

Products: NA

Alternate protein names: Rieske-type oxygenase; RO [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MRMHDTDEIRLIEAQAVPTRFARGWHCLGLIRDFGDGKPHPIDAFGQKLVVFRGGDGAINVLDGYCRHMGGDLSRGEVKG
NEIACPFHDWRWGGDGRCKQVPYSRRTPRLARTRAWTTLQQDGMLFVWNDPEGNPPPPEVTIPRIEGAGSDEWTDWHWYS
TVVQSNCREIIDNVVDMAHFFYIHGSLPKQFKNIFEGHVATQYMNSAGRPDIGGEGARMLGTTSVASYWGPSFMIDDLTY
HYEDADHQTVLINCHYPIDANSFVLQYGIIVKKSDALPDDLAMQTAIALGDFVKLGFEQDVEIWRHKARIDNPLLVEEDG
PVYQLRRWYQQFYVDVADVQPDMVDRFEFELDTTRPYAAWMKEVEANLAARA

Sequences:

>Translated_372_residues
MRMHDTDEIRLIEAQAVPTRFARGWHCLGLIRDFGDGKPHPIDAFGQKLVVFRGGDGAINVLDGYCRHMGGDLSRGEVKG
NEIACPFHDWRWGGDGRCKQVPYSRRTPRLARTRAWTTLQQDGMLFVWNDPEGNPPPPEVTIPRIEGAGSDEWTDWHWYS
TVVQSNCREIIDNVVDMAHFFYIHGSLPKQFKNIFEGHVATQYMNSAGRPDIGGEGARMLGTTSVASYWGPSFMIDDLTY
HYEDADHQTVLINCHYPIDANSFVLQYGIIVKKSDALPDDLAMQTAIALGDFVKLGFEQDVEIWRHKARIDNPLLVEEDG
PVYQLRRWYQQFYVDVADVQPDMVDRFEFELDTTRPYAAWMKEVEANLAARA
>Mature_372_residues
MRMHDTDEIRLIEAQAVPTRFARGWHCLGLIRDFGDGKPHPIDAFGQKLVVFRGGDGAINVLDGYCRHMGGDLSRGEVKG
NEIACPFHDWRWGGDGRCKQVPYSRRTPRLARTRAWTTLQQDGMLFVWNDPEGNPPPPEVTIPRIEGAGSDEWTDWHWYS
TVVQSNCREIIDNVVDMAHFFYIHGSLPKQFKNIFEGHVATQYMNSAGRPDIGGEGARMLGTTSVASYWGPSFMIDDLTY
HYEDADHQTVLINCHYPIDANSFVLQYGIIVKKSDALPDDLAMQTAIALGDFVKLGFEQDVEIWRHKARIDNPLLVEEDG
PVYQLRRWYQQFYVDVADVQPDMVDRFEFELDTTRPYAAWMKEVEANLAARA

Specific function: Catalyzes the opening of ring B of 1,4-androstadiene- 3,17,-dione (ADD) and 4-androstene-3,17-dione (ADD) with concomitant aromatization of ring A. The ring B is subsequently hydroxylated to yield a catechol and then subject to meta- cleavage [H]

COG id: COG4638

COG function: function code PR; Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Rieske domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71983709, Length=346, Percent_Identity=28.3236994219653, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI161085896, Length=379, Percent_Identity=24.802110817942, Blast_Score=116, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017941 [H]

Pfam domain/function: PF00355 Rieske [H]

EC number: 1.14.1.- [C]

Molecular weight: Translated: 42445; Mature: 42445

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMHDTDEIRLIEAQAVPTRFARGWHCLGLIRDFGDGKPHPIDAFGQKLVVFRGGDGAIN
CCCCCCCCEEEEEECCCCHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEH
VLDGYCRHMGGDLSRGEVKGNEIACPFHDWRWGGDGRCKQVPYSRRTPRLARTRAWTTLQ
HHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHEEC
QDGMLFVWNDPEGNPPPPEVTIPRIEGAGSDEWTDWHWYSTVVQSNCREIIDNVVDMAHF
CCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FYIHGSLPKQFKNIFEGHVATQYMNSAGRPDIGGEGARMLGTTSVASYWGPSFMIDDLTY
EEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHHCCCCEEEECEEE
HYEDADHQTVLINCHYPIDANSFVLQYGIIVKKSDALPDDLAMQTAIALGDFVKLGFEQD
EECCCCCCEEEEEEECCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHH
VEIWRHKARIDNPLLVEEDGPVYQLRRWYQQFYVDVADVQPDMVDRFEFELDTTRPYAAW
HHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHEEEEECCCCHHHHH
MKEVEANLAARA
HHHHHHHHHCCC
>Mature Secondary Structure
MRMHDTDEIRLIEAQAVPTRFARGWHCLGLIRDFGDGKPHPIDAFGQKLVVFRGGDGAIN
CCCCCCCCEEEEEECCCCHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEH
VLDGYCRHMGGDLSRGEVKGNEIACPFHDWRWGGDGRCKQVPYSRRTPRLARTRAWTTLQ
HHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHEEC
QDGMLFVWNDPEGNPPPPEVTIPRIEGAGSDEWTDWHWYSTVVQSNCREIIDNVVDMAHF
CCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FYIHGSLPKQFKNIFEGHVATQYMNSAGRPDIGGEGARMLGTTSVASYWGPSFMIDDLTY
EEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHHCCCCEEEECEEE
HYEDADHQTVLINCHYPIDANSFVLQYGIIVKKSDALPDDLAMQTAIALGDFVKLGFEQD
EECCCCCCEEEEEEECCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHH
VEIWRHKARIDNPLLVEEDGPVYQLRRWYQQFYVDVADVQPDMVDRFEFELDTTRPYAAW
HHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHEEEEECCCCHHHHH
MKEVEANLAARA
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]