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The map label for this gene is ptsJ [H]

Identifier: 41407365

GI number: 41407365

Start: 1348982

End: 1350310

Strand: Direct

Name: ptsJ [H]

Synonym: MAP1267

Alternate gene names: 41407365

Gene position: 1348982-1350310 (Clockwise)

Preceding gene: 41407363

Following gene: 41407372

Centisome position: 27.93

GC content: 75.85

Gene sequence:

>1329_bases
GTGGCAGTACATAAGAGCATAACCGCGACGGGTGCGGAATCCATAGCCGCCAGCATCGAAGCGGCCATCTCGGCCGGCTC
GCTGGCGCCCGGCGATGCGCTGCCGCCGGTCCGCGAGCTGGCTGCGCGGCTCGGCGTGAACGCCAACACGGCCGCGGCGG
CCTACCGCCTACTGCGGCATCGGGGCGCGGTCGAGACCGCGGGCCGGCGCGGCACCCGGGTGCGGCACCGGCCGGCGACC
ACCCCGCGATCGCTGCTCGGGCTCGACGTCCCCGCCGGCGTGCGTGACCTGTCGACCGGCAACCCGCACCCCGCCCTGTT
ACCCCTCGCCGCCGCCGCGCCGGCCCGCCCGGCCTCCGGCCGCGCGGTCCTCTACGGCGAGCCGGCCATCTCGCCGGCGC
TGGGGGAGTACGCCCGGGCCGCGCTGTCCGCCGACGGCGTGCCCGCCGATCACCTGGCGCTGACCAGCGGCGCGCTGGAC
GGCATCGAGCGCGCGCTGACCGCACATCTGCGTCCCGGTGATCGCGTCGCCGTCGAGGATCCGGGCTGGGCGAATCTCCT
CGATCTGCTTGCCGCACTCGGGTTTTCGGCTGAGCCGGTGCGGGTCGACGACGACGGGCCGCTGCCCGAGGACCTGGCCC
GCGCGTTGGGCCGCGGCGCGCGGGCGCTGGTGCTGACCACGCGCGCGCAGAACCCGACCGGTGCCGCGCTGTCGGCGGAT
CGCGCCGCGGCGCTGCGAGATCTGTTGTCCGGGCGGGCCGACGACGTCCTGCTGGTCGAAGACGACCACTGCGCGGGCAT
TTCCGGCGCGGCCCTGCACCCCGTGGCCGGCTGCACCGCGCATTGGGCGTTCGTCCGCTCGGCGTCCAAGGCCTACGGCC
CAGACCTGCGGGTGGCGGTGCTGGCCGGCGACCAGCGCACCGTGGATCGGGTGCACGGCCGGTTGCGGCTCGGCCCGGGC
TGGGTGAGCCACGTCCTGCAGCAGCTGGCCGTCGAATTATGGTCCGACACAGCGGCGTCCGAGCTCGTCGCGACGGCCGA
GCGGCGCTATGCCGACCGCCGCCGCCGGCTGTGCGGCGCGCTGGCCGAGCGGGGTGTCGACGCGCACGGCCGGTCCGGGC
TCAACGTGTGGGTTCGCGTTCCCGACGAGGCGGTCGCGGTATCCCGGTTGCTCGGCGCGGGCTGGGCGGCCGCGCCGGGT
GCCCGGTTCCGGATGCAGACGCCGGCGGGCATCCGCATCACCATCGCCGACCTGACACCCGACGAGATCGAACCGCTCGC
CGACGCCGTCGCACAGGCGGTGCGCCCCAGCGGGCGGCCCATCGTCTGA

Upstream 100 bases:

>100_bases
TAGCGCGCCCGTTCCCGGTAGCGGGTCGGCGTGCTGCGCGGCGTCGGCTGGTAGTCGGCTTCGGTCGACATAGATATTGT
CCTAGTACATAATCTGTTGC

Downstream 100 bases:

>100_bases
CCGCGGATCAGGCGCCGTCGCCGGGCATGTCGATGCCGGGGCCCTTCCACAGCATCTCGATGCTGGCGTGCGGGGGTACG
TCGTGGCGCGCCGGGCGCCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MAVHKSITATGAESIAASIEAAISAGSLAPGDALPPVRELAARLGVNANTAAAAYRLLRHRGAVETAGRRGTRVRHRPAT
TPRSLLGLDVPAGVRDLSTGNPHPALLPLAAAAPARPASGRAVLYGEPAISPALGEYARAALSADGVPADHLALTSGALD
GIERALTAHLRPGDRVAVEDPGWANLLDLLAALGFSAEPVRVDDDGPLPEDLARALGRGARALVLTTRAQNPTGAALSAD
RAAALRDLLSGRADDVLLVEDDHCAGISGAALHPVAGCTAHWAFVRSASKAYGPDLRVAVLAGDQRTVDRVHGRLRLGPG
WVSHVLQQLAVELWSDTAASELVATAERRYADRRRRLCGALAERGVDAHGRSGLNVWVRVPDEAVAVSRLLGAGWAAAPG
ARFRMQTPAGIRITIADLTPDEIEPLADAVAQAVRPSGRPIV

Sequences:

>Translated_442_residues
MAVHKSITATGAESIAASIEAAISAGSLAPGDALPPVRELAARLGVNANTAAAAYRLLRHRGAVETAGRRGTRVRHRPAT
TPRSLLGLDVPAGVRDLSTGNPHPALLPLAAAAPARPASGRAVLYGEPAISPALGEYARAALSADGVPADHLALTSGALD
GIERALTAHLRPGDRVAVEDPGWANLLDLLAALGFSAEPVRVDDDGPLPEDLARALGRGARALVLTTRAQNPTGAALSAD
RAAALRDLLSGRADDVLLVEDDHCAGISGAALHPVAGCTAHWAFVRSASKAYGPDLRVAVLAGDQRTVDRVHGRLRLGPG
WVSHVLQQLAVELWSDTAASELVATAERRYADRRRRLCGALAERGVDAHGRSGLNVWVRVPDEAVAVSRLLGAGWAAAPG
ARFRMQTPAGIRITIADLTPDEIEPLADAVAQAVRPSGRPIV
>Mature_441_residues
AVHKSITATGAESIAASIEAAISAGSLAPGDALPPVRELAARLGVNANTAAAAYRLLRHRGAVETAGRRGTRVRHRPATT
PRSLLGLDVPAGVRDLSTGNPHPALLPLAAAAPARPASGRAVLYGEPAISPALGEYARAALSADGVPADHLALTSGALDG
IERALTAHLRPGDRVAVEDPGWANLLDLLAALGFSAEPVRVDDDGPLPEDLARALGRGARALVLTTRAQNPTGAALSADR
AAALRDLLSGRADDVLLVEDDHCAGISGAALHPVAGCTAHWAFVRSASKAYGPDLRVAVLAGDQRTVDRVHGRLRLGPGW
VSHVLQQLAVELWSDTAASELVATAERRYADRRRRLCGALAERGVDAHGRSGLNVWVRVPDEAVAVSRLLGAGWAAAPGA
RFRMQTPAGIRITIADLTPDEIEPLADAVAQAVRPSGRPIV

Specific function: Putative transcriptional regulator of the ptsHI/crr operon [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=402, Percent_Identity=21.1442786069652, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI33469970, Length=402, Percent_Identity=21.1442786069652, Blast_Score=76, Evalue=8e-14,
Organism=Escherichia coli, GI1787710, Length=424, Percent_Identity=25.4716981132075, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790797, Length=331, Percent_Identity=25.3776435045317, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 45751; Mature: 45620

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVHKSITATGAESIAASIEAAISAGSLAPGDALPPVRELAARLGVNANTAAAAYRLLRH
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHH
RGAVETAGRRGTRVRHRPATTPRSLLGLDVPAGVRDLSTGNPHPALLPLAAAAPARPASG
CCCHHHCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHCCCCCCCCCEEEHHHCCCCCCCCC
RAVLYGEPAISPALGEYARAALSADGVPADHLALTSGALDGIERALTAHLRPGDRVAVED
CEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
PGWANLLDLLAALGFSAEPVRVDDDGPLPEDLARALGRGARALVLTTRAQNPTGAALSAD
CCHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHH
RAAALRDLLSGRADDVLLVEDDHCAGISGAALHPVAGCTAHWAFVRSASKAYGPDLRVAV
HHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEE
LAGDQRTVDRVHGRLRLGPGWVSHVLQQLAVELWSDTAASELVATAERRYADRRRRLCGA
EECCCHHHHHHCCEEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LAERGVDAHGRSGLNVWVRVPDEAVAVSRLLGAGWAAAPGARFRMQTPAGIRITIADLTP
HHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEEEECCCH
DEIEPLADAVAQAVRPSGRPIV
HHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AVHKSITATGAESIAASIEAAISAGSLAPGDALPPVRELAARLGVNANTAAAAYRLLRH
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHH
RGAVETAGRRGTRVRHRPATTPRSLLGLDVPAGVRDLSTGNPHPALLPLAAAAPARPASG
CCCHHHCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHCCCCCCCCCEEEHHHCCCCCCCCC
RAVLYGEPAISPALGEYARAALSADGVPADHLALTSGALDGIERALTAHLRPGDRVAVED
CEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
PGWANLLDLLAALGFSAEPVRVDDDGPLPEDLARALGRGARALVLTTRAQNPTGAALSAD
CCHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHH
RAAALRDLLSGRADDVLLVEDDHCAGISGAALHPVAGCTAHWAFVRSASKAYGPDLRVAV
HHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEE
LAGDQRTVDRVHGRLRLGPGWVSHVLQQLAVELWSDTAASELVATAERRYADRRRRLCGA
EECCCHHHHHHCCEEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LAERGVDAHGRSGLNVWVRVPDEAVAVSRLLGAGWAAAPGARFRMQTPAGIRITIADLTP
HHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEEEECCCH
DEIEPLADAVAQAVRPSGRPIV
HHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7612925; 11677609 [H]