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The map label for this gene is inhA

Identifier: 41407308

GI number: 41407308

Start: 1271224

End: 1272033

Strand: Direct

Name: inhA

Synonym: MAP1210

Alternate gene names: 41407308

Gene position: 1271224-1272033 (Clockwise)

Preceding gene: 41407307

Following gene: 41407309

Centisome position: 26.32

GC content: 67.53

Gene sequence:

>810_bases
ATGGCAGGACTGCTCGACGGCAAACGGATCCTGGTCACCGGGATCATCACCGACTCGTCGATCGCGTTTCACATCGCCAA
GGTGGCCCAGGAGGCCGGGGCGCAGTTGGTGCTGACCGGCTTCGACCGGCTGCGGCTGATCCAGCGCATCGTCGACCGGC
TGCCGGAGAAGGCCCCGTTGATCGAGCTCGACGTGCAGAACGAGGAGCACCTGAACACCCTGGCCCAACGGGTGACCGCC
GAGATCGGCGAGGGCAACAGGCTCGACGGGGTGGTGCACTCGATCGGCTTCATGCCACAGACCGGCATGGGCATCAACCC
GTTCTTCGACGCGCCGTACGAGGATGTCTCCAAAGGCATTCATATCTCGGCGTATTCGTACGCCTCGCTGGCCAAGGCGC
TGCTGCCGATCATGAACCCCGGCGGGTCGATCGTGGGCATGGACTTCGACCCCAGCCGGGCGATGCCGGCCTACAACTGG
ATGACGGTCGCGAAGAGCGCGCTGGAGTCGGTCAACCGGTTCGTGGCGCGCGAGGCCGGGCCGCACGGTGTGCGCTCGAA
TCTCGTTGCGGCGGGCCCGATCCGCACGCTGGCGATGGCCGGGATCGTCGGCGGCGTGCTCGGCGACCAGGCGGCCGAGC
AGATCCGGCTGCTTGAGGAGGGCTGGGATCAGCGGGCCCCGATCGGCTGGAACATGAAGGACCCCACCCCGGTGGCCAAG
ACGGTGTGCGCGCTGCTGTCCGACTGGCTGCCGGCCACCACCGGCACCATCATCTACGCCGACGGCGGCGCCAGCACCCA
ATTGCTGTAG

Upstream 100 bases:

>100_bases
GAGGACGCCAGTTACATCGCCGGCGCGGTGATCCCCGTCGACGGCGGTATGGGCATGGGCCACTGATTCCAACCAGCACA
CAAGGACATTAAGGACGGAC

Downstream 100 bases:

>100_bases
ACGGGCAATGGATTTCGACGCCGTCCTGCTGCTGTCCTTCGGCGGGCCGGAAGGGCCCGAGCAGGTGCGGCCGTTCTTGG
AGAACGTCACCCGGGGCCGC

Product: enoyl-(acyl carrier protein) reductase

Products: NA

Alternate protein names: NADH-dependent enoyl-ACP reductase [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MAGLLDGKRILVTGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRIVDRLPEKAPLIELDVQNEEHLNTLAQRVTA
EIGEGNRLDGVVHSIGFMPQTGMGINPFFDAPYEDVSKGIHISAYSYASLAKALLPIMNPGGSIVGMDFDPSRAMPAYNW
MTVAKSALESVNRFVAREAGPHGVRSNLVAAGPIRTLAMAGIVGGVLGDQAAEQIRLLEEGWDQRAPIGWNMKDPTPVAK
TVCALLSDWLPATTGTIIYADGGASTQLL

Sequences:

>Translated_269_residues
MAGLLDGKRILVTGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRIVDRLPEKAPLIELDVQNEEHLNTLAQRVTA
EIGEGNRLDGVVHSIGFMPQTGMGINPFFDAPYEDVSKGIHISAYSYASLAKALLPIMNPGGSIVGMDFDPSRAMPAYNW
MTVAKSALESVNRFVAREAGPHGVRSNLVAAGPIRTLAMAGIVGGVLGDQAAEQIRLLEEGWDQRAPIGWNMKDPTPVAK
TVCALLSDWLPATTGTIIYADGGASTQLL
>Mature_268_residues
AGLLDGKRILVTGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRIVDRLPEKAPLIELDVQNEEHLNTLAQRVTAE
IGEGNRLDGVVHSIGFMPQTGMGINPFFDAPYEDVSKGIHISAYSYASLAKALLPIMNPGGSIVGMDFDPSRAMPAYNWM
TVAKSALESVNRFVAREAGPHGVRSNLVAAGPIRTLAMAGIVGGVLGDQAAEQIRLLEEGWDQRAPIGWNMKDPTPVAKT
VCALLSDWLPATTGTIIYADGGASTQLL

Specific function: Fatty acid biosynthesis pathway; second reduction step. [C]

COG id: COG0623

COG function: function code I; Enoyl-[acyl-carrier-protein] reductase (NADH)

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787545, Length=268, Percent_Identity=33.2089552238806, Blast_Score=126, Evalue=1e-30,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR014358
- InterPro:   IPR016040 [H]

Pfam domain/function: NA

EC number: =1.3.1.9 [H]

Molecular weight: Translated: 28725; Mature: 28594

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLLDGKRILVTGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRIVDRLPEKAPL
CCCCCCCCEEEEEEEEECCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCE
IELDVQNEEHLNTLAQRVTAEIGEGNRLDGVVHSIGFMPQTGMGINPFFDAPYEDVSKGI
EEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCE
HISAYSYASLAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAG
EEEHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PHGVRSNLVAAGPIRTLAMAGIVGGVLGDQAAEQIRLLEEGWDQRAPIGWNMKDPTPVAK
CCCHHHCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
TVCALLSDWLPATTGTIIYADGGASTQLL
HHHHHHHHHCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
AGLLDGKRILVTGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRIVDRLPEKAPL
CCCCCCCEEEEEEEEECCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCE
IELDVQNEEHLNTLAQRVTAEIGEGNRLDGVVHSIGFMPQTGMGINPFFDAPYEDVSKGI
EEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCE
HISAYSYASLAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAG
EEEHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PHGVRSNLVAAGPIRTLAMAGIVGGVLGDQAAEQIRLLEEGWDQRAPIGWNMKDPTPVAK
CCCHHHCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
TVCALLSDWLPATTGTIIYADGGASTQLL
HHHHHHHHHCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9534249 [H]