| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is fabG1
Identifier: 41407307
GI number: 41407307
Start: 1270422
End: 1271189
Strand: Direct
Name: fabG1
Synonym: MAP1209
Alternate gene names: 41407307
Gene position: 1270422-1271189 (Clockwise)
Preceding gene: 41407306
Following gene: 41407308
Centisome position: 26.3
GC content: 69.01
Gene sequence:
>768_bases GTGACTGACACGGCCACCGAGAACACCACCGAAAGTGCCGCCGACTACGGCAGACCGGCATTCGTCTCCCGCTCCGTCCT GGTGACCGGAGGAAACCGGGGCATCGGTCTGGCGATCGCCCAGCGGCTGGCCGCCGACGGCCACAAGGTGGCCGTCACGC ACCGCGGATCCGGGGCGCCCGACGGGCTGTTCGGTGTCGAGTGCGACGTCACCGACAACGACGCCGTCGACCGCGCCTTC ACAGAGGTGGAGGAGCACCAGGGGCCGGTCGAGGTGCTGGTGTCCAACGCCGGTATCTCCAAGGACGCATTCCTGATCCG GATGACCGAGGAGCGGTTCACCGAGGTCATCAACGCCAACCTGACCGGGGCGTTCCGGGTGACCCAGCGCGCGGCGCGCA GCATGCAGAAAAAGCGGTTCGGCCGCATCATCTACATCGGCTCGGTGTCCGGCATGTGGGGCATCGGCAACCAGTCCAAT TACGCGGCCGCCAAGGCCGGCCTGATCGGGATGGCCCGCTCGATCTCCCGCGAACTGTCCAAGGCGGGTGTGACCGCCAA CGTCGTCGCGCCCGGCTACATCGACACCGAGATGACCCGCGCCCTGGACGAGCGGATCCAGGCGGGCGCGCTGGAGTTCA TCCCGGCCAAGCGGGTCGGCACCGCCGCGGAGGTCGCCGGGGCCGTCAGCTTCCTGGCCTCCGAGGACGCCAGTTACATC GCCGGCGCGGTGATCCCCGTCGACGGCGGTATGGGCATGGGCCACTGA
Upstream 100 bases:
>100_bases CGTAACGCCACGGCGCAAACTCGCCCGGATTTCCGCCCTGGCGTTACGAGCGGGGCCAGCCGGTTTCCGGGCCGATCAGC CGAGGCGATAGGTTGACGGG
Downstream 100 bases:
>100_bases TTCCAACCAGCACACAAGGACATTAAGGACGGACATGGCAGGACTGCTCGACGGCAAACGGATCCTGGTCACCGGGATCA TCACCGACTCGTCGATCGCG
Product: FabG1
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 255; Mature: 254
Protein sequence:
>255_residues MTDTATENTTESAADYGRPAFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPDGLFGVECDVTDNDAVDRAF TEVEEHQGPVEVLVSNAGISKDAFLIRMTEERFTEVINANLTGAFRVTQRAARSMQKKRFGRIIYIGSVSGMWGIGNQSN YAAAKAGLIGMARSISRELSKAGVTANVVAPGYIDTEMTRALDERIQAGALEFIPAKRVGTAAEVAGAVSFLASEDASYI AGAVIPVDGGMGMGH
Sequences:
>Translated_255_residues MTDTATENTTESAADYGRPAFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPDGLFGVECDVTDNDAVDRAF TEVEEHQGPVEVLVSNAGISKDAFLIRMTEERFTEVINANLTGAFRVTQRAARSMQKKRFGRIIYIGSVSGMWGIGNQSN YAAAKAGLIGMARSISRELSKAGVTANVVAPGYIDTEMTRALDERIQAGALEFIPAKRVGTAAEVAGAVSFLASEDASYI AGAVIPVDGGMGMGH >Mature_254_residues TDTATENTTESAADYGRPAFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPDGLFGVECDVTDNDAVDRAFT EVEEHQGPVEVLVSNAGISKDAFLIRMTEERFTEVINANLTGAFRVTQRAARSMQKKRFGRIIYIGSVSGMWGIGNQSNY AAAKAGLIGMARSISRELSKAGVTANVVAPGYIDTEMTRALDERIQAGALEFIPAKRVGTAAEVAGAVSFLASEDASYIA GAVIPVDGGMGMGH
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=234, Percent_Identity=38.4615384615385, Blast_Score=153, Evalue=1e-37, Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=38.4615384615385, Blast_Score=143, Evalue=2e-34, Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=30.1204819277108, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=27.9835390946502, Blast_Score=98, Evalue=7e-21, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=27.6, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI4504505, Length=190, Percent_Identity=35.2631578947368, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI7705925, Length=238, Percent_Identity=30.2521008403361, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=28.4615384615385, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI4758504, Length=248, Percent_Identity=31.8548387096774, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI31542939, Length=242, Percent_Identity=25.6198347107438, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI66933014, Length=195, Percent_Identity=28.7179487179487, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI7657478, Length=190, Percent_Identity=30.5263157894737, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI20149619, Length=191, Percent_Identity=29.3193717277487, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI59889578, Length=204, Percent_Identity=31.3725490196078, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI223718074, Length=188, Percent_Identity=31.9148936170213, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI4503301, Length=191, Percent_Identity=30.8900523560209, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI109715829, Length=233, Percent_Identity=24.4635193133047, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=25.2577319587629, Blast_Score=71, Evalue=7e-13, Organism=Homo sapiens, GI83715985, Length=248, Percent_Identity=30.6451612903226, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI25282469, Length=159, Percent_Identity=28.3018867924528, Blast_Score=68, Evalue=6e-12, Organism=Homo sapiens, GI4503817, Length=203, Percent_Identity=23.6453201970443, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI224922801, Length=167, Percent_Identity=28.7425149700599, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI150247226, Length=203, Percent_Identity=31.5270935960591, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=27.5303643724696, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=47.3029045643153, Blast_Score=211, Evalue=4e-56, Organism=Escherichia coli, GI1790717, Length=241, Percent_Identity=32.7800829875519, Blast_Score=127, Evalue=7e-31, Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=35.2697095435685, Blast_Score=119, Evalue=1e-28, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=34.1463414634146, Blast_Score=116, Evalue=2e-27, Organism=Escherichia coli, GI87082160, Length=239, Percent_Identity=32.2175732217573, Blast_Score=110, Evalue=8e-26, Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=28.1124497991968, Blast_Score=104, Evalue=5e-24, Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=31.6872427983539, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1789208, Length=178, Percent_Identity=34.2696629213483, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1786812, Length=245, Percent_Identity=31.0204081632653, Blast_Score=97, Evalue=8e-22, Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=29.2490118577075, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=28.4, Blast_Score=77, Evalue=9e-16, Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=27.0833333333333, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1786701, Length=213, Percent_Identity=29.1079812206573, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=26.6666666666667, Blast_Score=61, Evalue=6e-11, Organism=Caenorhabditis elegans, GI25147288, Length=242, Percent_Identity=38.8429752066116, Blast_Score=150, Evalue=6e-37, Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=35.2941176470588, Blast_Score=149, Evalue=1e-36, Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=29.6747967479675, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=28, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=29.6, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=28.6259541984733, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17538182, Length=247, Percent_Identity=28.3400809716599, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17568967, Length=189, Percent_Identity=30.6878306878307, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=29.1666666666667, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=26.4, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=30.6201550387597, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=27.6923076923077, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=27.7566539923954, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=26.6409266409266, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=26.615969581749, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17561272, Length=199, Percent_Identity=29.6482412060301, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=28.5185185185185, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=25.7692307692308, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17508651, Length=248, Percent_Identity=28.6290322580645, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=27.6515151515151, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17536025, Length=258, Percent_Identity=28.6821705426357, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=27.6515151515151, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=25.9541984732824, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI193203117, Length=231, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI193203115, Length=231, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17562908, Length=271, Percent_Identity=26.9372693726937, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17562990, Length=268, Percent_Identity=28.3582089552239, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17564282, Length=254, Percent_Identity=25.9842519685039, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=28.996282527881, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=26.0416666666667, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=27.7566539923954, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17558006, Length=208, Percent_Identity=27.8846153846154, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=27.9245283018868, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=29.8892988929889, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17507613, Length=210, Percent_Identity=27.1428571428571, Blast_Score=65, Evalue=5e-11, Organism=Caenorhabditis elegans, GI32563809, Length=211, Percent_Identity=27.0142180094787, Blast_Score=64, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=193, Percent_Identity=33.6787564766839, Blast_Score=103, Evalue=3e-23, Organism=Saccharomyces cerevisiae, GI6324126, Length=185, Percent_Identity=28.6486486486486, Blast_Score=92, Evalue=6e-20, Organism=Saccharomyces cerevisiae, GI6320089, Length=241, Percent_Identity=28.6307053941909, Blast_Score=87, Evalue=3e-18, Organism=Drosophila melanogaster, GI24639444, Length=238, Percent_Identity=36.1344537815126, Blast_Score=135, Evalue=2e-32, Organism=Drosophila melanogaster, GI21355319, Length=239, Percent_Identity=30.9623430962343, Blast_Score=122, Evalue=2e-28, Organism=Drosophila melanogaster, GI23397609, Length=241, Percent_Identity=33.195020746888, Blast_Score=108, Evalue=3e-24, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=30.1587301587302, Blast_Score=97, Evalue=7e-21, Organism=Drosophila melanogaster, GI18859837, Length=192, Percent_Identity=34.8958333333333, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=30.2788844621514, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=29.3650793650794, Blast_Score=94, Evalue=9e-20, Organism=Drosophila melanogaster, GI24644337, Length=220, Percent_Identity=31.3636363636364, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI17737361, Length=248, Percent_Identity=31.0483870967742, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI24641232, Length=198, Percent_Identity=30.3030303030303, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI21356301, Length=262, Percent_Identity=28.2442748091603, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI116007234, Length=197, Percent_Identity=31.9796954314721, Blast_Score=78, Evalue=7e-15, Organism=Drosophila melanogaster, GI24643142, Length=237, Percent_Identity=27.0042194092827, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI28571387, Length=199, Percent_Identity=27.1356783919598, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI116007236, Length=194, Percent_Identity=27.8350515463918, Blast_Score=70, Evalue=9e-13, Organism=Drosophila melanogaster, GI24581726, Length=149, Percent_Identity=27.5167785234899, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24649181, Length=185, Percent_Identity=28.1081081081081, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI116007232, Length=176, Percent_Identity=32.3863636363636, Blast_Score=68, Evalue=5e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26668; Mature: 26537
Theoretical pI: Translated: 5.72; Mature: 5.72
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTDTATENTTESAADYGRPAFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAP CCCCCCCCCCHHHHHCCCCCCEECEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCC DGLFGVECDVTDNDAVDRAFTEVEEHQGPVEVLVSNAGISKDAFLIRMTEERFTEVINAN CCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECHHHHHHHHCCC LTGAFRVTQRAARSMQKKRFGRIIYIGSVSGMWGIGNQSNYAAAKAGLIGMARSISRELS CCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH KAGVTANVVAPGYIDTEMTRALDERIQAGALEFIPAKRVGTAAEVAGAVSFLASEDASYI HCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEECCCHHCCHHHHHHHHHHHHHCCCCCHH AGAVIPVDGGMGMGH EEEEEECCCCCCCCC >Mature Secondary Structure TDTATENTTESAADYGRPAFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAP CCCCCCCCCHHHHHCCCCCCEECEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCC DGLFGVECDVTDNDAVDRAFTEVEEHQGPVEVLVSNAGISKDAFLIRMTEERFTEVINAN CCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECHHHHHHHHCCC LTGAFRVTQRAARSMQKKRFGRIIYIGSVSGMWGIGNQSNYAAAKAGLIGMARSISRELS CCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH KAGVTANVVAPGYIDTEMTRALDERIQAGALEFIPAKRVGTAAEVAGAVSFLASEDASYI HCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEECCCHHCCHHHHHHHHHHHHHCCCCCHH AGAVIPVDGGMGMGH EEEEEECCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9534249 [H]