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The map label for this gene is secF

Identifier: 41407142

GI number: 41407142

Start: 1092251

End: 1093558

Strand: Direct

Name: secF

Synonym: MAP1044

Alternate gene names: 41407142

Gene position: 1092251-1093558 (Clockwise)

Preceding gene: 41407141

Following gene: 41407143

Centisome position: 22.61

GC content: 70.8

Gene sequence:

>1308_bases
ATGACTTCCTCCAAGGCCTCCAAAGCCGCCAAGGGCGCGACCGAGATCACCGAAACCTCTTCGGGCGCTTCGGAATTGAC
CGACAGCGACGCCGCCGCGGCCGGGCTGCCGCGGCACAGCTTCCTGTCCCGCCTCTACACCGGCACCGGCGCGTTCGAGG
TGGTCGGGCGGCGCCGGCTGTGGTTCGGCATCAGCGGCGCGATCGTCGCGGTCGCGATCCTGTCCATCGCGCTGCGCGGC
TTCACCTTCGGCATCGACTTCAACGGCGGCACCACGGTGTCGATGCCCGCCGCCGGGACGCACGGCACGGTGCACACCGC
GCAGGTGCAGGAGGTGTTCCGCAAGACCCTCGGCACCGACCCGGAGTCGGTGGTCGTGGTCGGCAACGGCGCCGCGGCCA
CCGTGCAGATCCGCTCCGAGACGCTGACCAACGACCAGACGACCAAGCTGCGCAACGCGCTGTTCGACGCGTTCGGACCC
AAGGGCGCCGACGGCAAGCCCAGCAAGCAGGCCATCAGCGACTCGCAGGTCTCGGAGACCTGGGGCGACCAGATCACCGA
CAAGGCGCTGATCGCGCTGGTGGTCTTCCTGGCGCTGGTCGGGCTCTACATCACGGTCCGCTACGAGCGGTACATGACGC
TGGCCGCCATCGCGGCGATGTTCTTCGACCTGACCGTGACGGCCGGCGTGTACTCGCTGGTGGGCTTCGAGGTCACCCCG
GCCACCGTCATCGGCCTGCTGACGATCCTGGGCTTCTCGCTCTACGACACCGTCATCGTGTTCGACAAGGTCGAGGAGAA
CACCCGCGACTTCCAGCACACCAACCGGCGCACCTTCGCCGAGCAGGCCAACCTGGCGATCAACCAGACGTTCATGCGCT
CCATCAACACCAGCCTGATCGGCGTGCTGCCGGTGCTGGCGCTGATGGTGGTGGCGGTCTGGCTGCTGGGCGTCGGCACG
CTGAAGGACCTGGCGCTGGTGCAGCTGGTCGGCATCCTGGTGGGCACCTACTCGTCGATCTTCGTCGCCACCCCGCTGCT
GGTCACGCTGCGCGAGCGCACCGAGCTGGTGCGCACCCACACCCGCCGGGTGCTCAAGCGGCGCGCCGGCGGCGCGCGGG
CGAGCGCCGAGAGCACCGCCGACGACGCCGCCGAGCCTCCCGCCGGGTCCGGGGACGAGGCCACCGAGGCCGAGCGGGAG
TCGCGGTCGTCCCGGCCCGCGCCGAGCAAGCCGGCGCCGGGTGCCCGGCCGGTGCGGCCCACTGGGGCCCGGCGTCCGAC
CGGCAAGCGGAACGTCGGCCGGCGGTAG

Upstream 100 bases:

>100_bases
CGACGCTGGCCAAGCCGGCCTACAACGGCCTGGGCGCTGTTCAGCAGGTCGCCCGCGAACGCCGGGCGGCGGCGCACGTG
AGCACGGGACAGGGATAGCG

Downstream 100 bases:

>100_bases
ACACGTGGCCATCCGCATCGGCCGTCGCGGCCTGACGGGGTGGGTGGGCATCGGTATGGCCGTGCTGGTCGTCGCGGGCG
TCGCCCTGGCCGGCTGCGCG

Product: preprotein translocase subunit SecF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MTSSKASKAAKGATEITETSSGASELTDSDAAAAGLPRHSFLSRLYTGTGAFEVVGRRRLWFGISGAIVAVAILSIALRG
FTFGIDFNGGTTVSMPAAGTHGTVHTAQVQEVFRKTLGTDPESVVVVGNGAAATVQIRSETLTNDQTTKLRNALFDAFGP
KGADGKPSKQAISDSQVSETWGDQITDKALIALVVFLALVGLYITVRYERYMTLAAIAAMFFDLTVTAGVYSLVGFEVTP
ATVIGLLTILGFSLYDTVIVFDKVEENTRDFQHTNRRTFAEQANLAINQTFMRSINTSLIGVLPVLALMVVAVWLLGVGT
LKDLALVQLVGILVGTYSSIFVATPLLVTLRERTELVRTHTRRVLKRRAGGARASAESTADDAAEPPAGSGDEATEAERE
SRSSRPAPSKPAPGARPVRPTGARRPTGKRNVGRR

Sequences:

>Translated_435_residues
MTSSKASKAAKGATEITETSSGASELTDSDAAAAGLPRHSFLSRLYTGTGAFEVVGRRRLWFGISGAIVAVAILSIALRG
FTFGIDFNGGTTVSMPAAGTHGTVHTAQVQEVFRKTLGTDPESVVVVGNGAAATVQIRSETLTNDQTTKLRNALFDAFGP
KGADGKPSKQAISDSQVSETWGDQITDKALIALVVFLALVGLYITVRYERYMTLAAIAAMFFDLTVTAGVYSLVGFEVTP
ATVIGLLTILGFSLYDTVIVFDKVEENTRDFQHTNRRTFAEQANLAINQTFMRSINTSLIGVLPVLALMVVAVWLLGVGT
LKDLALVQLVGILVGTYSSIFVATPLLVTLRERTELVRTHTRRVLKRRAGGARASAESTADDAAEPPAGSGDEATEAERE
SRSSRPAPSKPAPGARPVRPTGARRPTGKRNVGRR
>Mature_434_residues
TSSKASKAAKGATEITETSSGASELTDSDAAAAGLPRHSFLSRLYTGTGAFEVVGRRRLWFGISGAIVAVAILSIALRGF
TFGIDFNGGTTVSMPAAGTHGTVHTAQVQEVFRKTLGTDPESVVVVGNGAAATVQIRSETLTNDQTTKLRNALFDAFGPK
GADGKPSKQAISDSQVSETWGDQITDKALIALVVFLALVGLYITVRYERYMTLAAIAAMFFDLTVTAGVYSLVGFEVTPA
TVIGLLTILGFSLYDTVIVFDKVEENTRDFQHTNRRTFAEQANLAINQTFMRSINTSLIGVLPVLALMVVAVWLLGVGTL
KDLALVQLVGILVGTYSSIFVATPLLVTLRERTELVRTHTRRVLKRRAGGARASAESTADDAAEPPAGSGDEATEAERES
RSSRPAPSKPAPGARPVRPTGARRPTGKRNVGRR

Specific function: Involved in protein export [H]

COG id: COG0341

COG function: function code U; Preprotein translocase subunit SecF

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786610, Length=312, Percent_Identity=27.2435897435897, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645
- InterPro:   IPR005665 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 46189; Mature: 46058

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSKASKAAKGATEITETSSGASELTDSDAAAAGLPRHSFLSRLYTGTGAFEVVGRRRL
CCCCHHHHHHCCCHHHHHCCCCHHHHCCCHHHHHCCCHHHHHHHHHCCCCHHHHHCCHHH
WFGISGAIVAVAILSIALRGFTFGIDFNGGTTVSMPAAGTHGTVHTAQVQEVFRKTLGTD
EECHHHHHHHHHHHHHHHHHEEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCC
PESVVVVGNGAAATVQIRSETLTNDQTTKLRNALFDAFGPKGADGKPSKQAISDSQVSET
CCEEEEEECCCEEEEEEECHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHCHHHHHHH
WGDQITDKALIALVVFLALVGLYITVRYERYMTLAAIAAMFFDLTVTAGVYSLVGFEVTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
ATVIGLLTILGFSLYDTVIVFDKVEENTRDFQHTNRRTFAEQANLAINQTFMRSINTSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLPVLALMVVAVWLLGVGTLKDLALVQLVGILVGTYSSIFVATPLLVTLRERTELVRTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRRVLKRRAGGARASAESTADDAAEPPAGSGDEATEAERESRSSRPAPSKPAPGARPVRP
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCC
TGARRPTGKRNVGRR
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSSKASKAAKGATEITETSSGASELTDSDAAAAGLPRHSFLSRLYTGTGAFEVVGRRRL
CCCHHHHHHCCCHHHHHCCCCHHHHCCCHHHHHCCCHHHHHHHHHCCCCHHHHHCCHHH
WFGISGAIVAVAILSIALRGFTFGIDFNGGTTVSMPAAGTHGTVHTAQVQEVFRKTLGTD
EECHHHHHHHHHHHHHHHHHEEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCC
PESVVVVGNGAAATVQIRSETLTNDQTTKLRNALFDAFGPKGADGKPSKQAISDSQVSET
CCEEEEEECCCEEEEEEECHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHCHHHHHHH
WGDQITDKALIALVVFLALVGLYITVRYERYMTLAAIAAMFFDLTVTAGVYSLVGFEVTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
ATVIGLLTILGFSLYDTVIVFDKVEENTRDFQHTNRRTFAEQANLAINQTFMRSINTSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLPVLALMVVAVWLLGVGTLKDLALVQLVGILVGTYSSIFVATPLLVTLRERTELVRTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRRVLKRRAGGARASAESTADDAAEPPAGSGDEATEAERESRSSRPAPSKPAPGARPVRP
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCC
TGARRPTGKRNVGRR
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]