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The map label for this gene is moaB2

Identifier: 41407017

GI number: 41407017

Start: 952221

End: 952778

Strand: Direct

Name: moaB2

Synonym: MAP0919

Alternate gene names: 41407017

Gene position: 952221-952778 (Clockwise)

Preceding gene: 41407016

Following gene: 41407022

Centisome position: 19.72

GC content: 69.0

Gene sequence:

>558_bases
GTGAGAGTGGACGAACCCTCGGCGGCGGGATTGTCGGAGCTCGGATATACGGTTGCACCCATGGAAACGGGTGCGGAGTT
GGTAGTTGGCCGGGCACTGGTCGTGGTGGTCGACGATCGCGCCGCCCACGGTGACGAGGACCACAGCGGGCCGCTGGTGA
CCGAGCTGCTCACCGAGGCGGGATTCGTCGTCGACGGTGTGGTCGCCGTCGCCGCCGACGAGGTCGAGATCCGCAACGCG
CTCAACACCGCGGTGATTGGCGGGGTGGACCTGGTCGTCTCCGTCGGCGGGACGGGCGTCACCCCGCGCGACGTCACTCC
GGAGGCCACCCGGGAGATCCTCGATCGCGAAATCCTCGGCATCGCCGAGGCCATCCGCGGCTCGGGGCTGTCCGCCGGCA
TCATCGACGCCGGCTTGTCACGCGGACTGGCCGGGGTGTCCGGCAGCACGCTGGTGGTCAACCTGGCCGGCTCCCGCTAT
GCGGTGCGCGACGGCATGGCGACGCTGAATCCGTTGGCGGCCCAGATCATTGGGCAGTTGTCGAGCCTGGAGATCTAG

Upstream 100 bases:

>100_bases
GGTCCAAGGCGCCGGGCGACAAGATCACGTTGACGTTCTCCGATCCCGCCGGCGGCGGCAGCCGGACTTTGCCGGTCACC
CTGGGAAAGGCGGACCAGTA

Downstream 100 bases:

>100_bases
ACCCGGGCTGCCCGGCGCCGGTCGTTACGACTCGGCCTCCGCGCGCGGCCCGTACTCGGGTGGGGGCGTGGTGCTCACGC
TTCCGTGCTTGCCCGACGAG

Product: MoaB2

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MRVDEPSAAGLSELGYTVAPMETGAELVVGRALVVVVDDRAAHGDEDHSGPLVTELLTEAGFVVDGVVAVAADEVEIRNA
LNTAVIGGVDLVVSVGGTGVTPRDVTPEATREILDREILGIAEAIRGSGLSAGIIDAGLSRGLAGVSGSTLVVNLAGSRY
AVRDGMATLNPLAAQIIGQLSSLEI

Sequences:

>Translated_185_residues
MRVDEPSAAGLSELGYTVAPMETGAELVVGRALVVVVDDRAAHGDEDHSGPLVTELLTEAGFVVDGVVAVAADEVEIRNA
LNTAVIGGVDLVVSVGGTGVTPRDVTPEATREILDREILGIAEAIRGSGLSAGIIDAGLSRGLAGVSGSTLVVNLAGSRY
AVRDGMATLNPLAAQIIGQLSSLEI
>Mature_185_residues
MRVDEPSAAGLSELGYTVAPMETGAELVVGRALVVVVDDRAAHGDEDHSGPLVTELLTEAGFVVDGVVAVAADEVEIRNA
LNTAVIGGVDLVVSVGGTGVTPRDVTPEATREILDREILGIAEAIRGSGLSAGIIDAGLSRGLAGVSGSTLVVNLAGSRY
AVRDGMATLNPLAAQIIGQLSSLEI

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=130, Percent_Identity=33.8461538461538, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI10880983, Length=130, Percent_Identity=33.8461538461538, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17564954, Length=162, Percent_Identity=35.1851851851852, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI17136978, Length=149, Percent_Identity=34.8993288590604, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24638841, Length=149, Percent_Identity=34.8993288590604, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18679; Mature: 18679

Theoretical pI: Translated: 4.03; Mature: 4.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVDEPSAAGLSELGYTVAPMETGAELVVGRALVVVVDDRAAHGDEDHSGPLVTELLTEA
CCCCCCCCCCHHHCCCEECCCCCCHHEEECEEEEEEEECCCCCCCCCCCCHHHHHHHHHC
GFVVDGVVAVAADEVEIRNALNTAVIGGVDLVVSVGGTGVTPRDVTPEATREILDREILG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
IAEAIRGSGLSAGIIDAGLSRGLAGVSGSTLVVNLAGSRYAVRDGMATLNPLAAQIIGQL
HHHHHHCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCEEEHHCCCHHHHHHHHHHHHHH
SSLEI
HHCCC
>Mature Secondary Structure
MRVDEPSAAGLSELGYTVAPMETGAELVVGRALVVVVDDRAAHGDEDHSGPLVTELLTEA
CCCCCCCCCCHHHCCCEECCCCCCHHEEECEEEEEEEECCCCCCCCCCCCHHHHHHHHHC
GFVVDGVVAVAADEVEIRNALNTAVIGGVDLVVSVGGTGVTPRDVTPEATREILDREILG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
IAEAIRGSGLSAGIIDAGLSRGLAGVSGSTLVVNLAGSRYAVRDGMATLNPLAAQIIGQL
HHHHHHCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCEEEHHCCCHHHHHHHHHHHHHH
SSLEI
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]