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The map label for this gene is cobF [H]

Identifier: 41406986

GI number: 41406986

Start: 914638

End: 915453

Strand: Direct

Name: cobF [H]

Synonym: MAP0888

Alternate gene names: 41406986

Gene position: 914638-915453 (Clockwise)

Preceding gene: 41406981

Following gene: 41406987

Centisome position: 18.94

GC content: 69.49

Gene sequence:

>816_bases
TTGCGGTCCCGACTAGGCCCTTGCGGTATCGATTCGGCAATGTGGGCGACAGAAGCAAGTCAGGAGGGTCGATTGGGGCG
GCACATCCACGTCATCGGCATCGGGGCCGGCGACCCCGACTACCTGACCGTGCAGGCGATCGAGGCGCTCAACGACACCC
AGGTGTTTTTCGCGATGGACAAGGGCGAGCAGAAGAGCGACCTGGTGGCGCTGCGACGCGAGATCTGCTCCCGGTTCATC
CGTCAGCCCGGCTACCGCTTCGTCGAGCTGCGCGACCCGAAGCGGTCCGACCGCGCCGACTACCGCGACGCGGTAGCGGA
ATGGCATGCCGCGCGCGCGCAGATCTGGGCCGACGCCATCGCCGCCGAACTCGGCCCGCACGGCGTCGGCGGCTTTCTGG
CCTGGGGCGATCCGTCGCTCTACGACAGCACGTTGCGCATCCTGGACACCGTCGCCGGGCACGTCGAATTCACCTTCGAC
GTGATCCCCGGCATCACCGCCGTGCAAGCGCTGACCGCCCGGCATCGCATCCCGCTCAACGAGGTGGGCGAGCCCGTGCT
CATCACCACCGGTCGCCAGCTGCGCGCCCACGGCATATCCGGCTCGGCGGTGGTGATGCTCGACGCCGACTGCTCGTTCC
AGCGGTGTGCGCCCGAGACCCGCATCTGGTGGGGCGCCTACCTGGGCACCGCCGACGAACTGCTGGTCGCCGGCACCGTC
GGCGAGGTGGGGCCCCGCATCGCGGCGCTGCGCGCGCAGGCCCGCGCCCGGCACGGCTGGATCATGGACACCTATTTGCT
GCGACCGGCACACTGA

Upstream 100 bases:

>100_bases
GTCGCTTCGGATCGTCTCGGCGCGCGTCATGGTCGGGTCCTCCTGATCGCTTGGCATCGTCGCCTCGGGCGCTTCAGACG
GTACCCATGGTACTGGGTAC

Downstream 100 bases:

>100_bases
AACCGTGCCCGAACTGCCCGAGATCGAAGCGCTGGCCGACCACCTGCGGCGCCATGCCGTCGGGCTGCCGATCGGCCGGG
TCGACGTCGCCGCCCTGTCC

Product: precorrin 6A synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MRSRLGPCGIDSAMWATEASQEGRLGRHIHVIGIGAGDPDYLTVQAIEALNDTQVFFAMDKGEQKSDLVALRREICSRFI
RQPGYRFVELRDPKRSDRADYRDAVAEWHAARAQIWADAIAAELGPHGVGGFLAWGDPSLYDSTLRILDTVAGHVEFTFD
VIPGITAVQALTARHRIPLNEVGEPVLITTGRQLRAHGISGSAVVMLDADCSFQRCAPETRIWWGAYLGTADELLVAGTV
GEVGPRIAALRAQARARHGWIMDTYLLRPAH

Sequences:

>Translated_271_residues
MRSRLGPCGIDSAMWATEASQEGRLGRHIHVIGIGAGDPDYLTVQAIEALNDTQVFFAMDKGEQKSDLVALRREICSRFI
RQPGYRFVELRDPKRSDRADYRDAVAEWHAARAQIWADAIAAELGPHGVGGFLAWGDPSLYDSTLRILDTVAGHVEFTFD
VIPGITAVQALTARHRIPLNEVGEPVLITTGRQLRAHGISGSAVVMLDADCSFQRCAPETRIWWGAYLGTADELLVAGTV
GEVGPRIAALRAQARARHGWIMDTYLLRPAH
>Mature_271_residues
MRSRLGPCGIDSAMWATEASQEGRLGRHIHVIGIGAGDPDYLTVQAIEALNDTQVFFAMDKGEQKSDLVALRREICSRFI
RQPGYRFVELRDPKRSDRADYRDAVAEWHAARAQIWADAIAAELGPHGVGGFLAWGDPSLYDSTLRILDTVAGHVEFTFD
VIPGITAVQALTARHRIPLNEVGEPVLITTGRQLRAHGISGSAVVMLDADCSFQRCAPETRIWWGAYLGTADELLVAGTV
GEVGPRIAALRAQARARHGWIMDTYLLRPAH

Specific function: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR012797 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.152 [H]

Molecular weight: Translated: 29735; Mature: 29735

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSRLGPCGIDSAMWATEASQEGRLGRHIHVIGIGAGDPDYLTVQAIEALNDTQVFFAMD
CCCCCCCCCCCHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEHEEHHHCCCCEEEEEEC
KGEQKSDLVALRREICSRFIRQPGYRFVELRDPKRSDRADYRDAVAEWHAARAQIWADAI
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AAELGPHGVGGFLAWGDPSLYDSTLRILDTVAGHVEFTFDVIPGITAVQALTARHRIPLN
HHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCEEEEEEHHCCHHHHHHHHHHCCCCHH
EVGEPVLITTGRQLRAHGISGSAVVMLDADCSFQRCAPETRIWWGAYLGTADELLVAGTV
HCCCCEEEECCCEEEECCCCCCEEEEEECCCCHHHCCCCCEEEEEHHHCCCCCEEEECCC
GEVGPRIAALRAQARARHGWIMDTYLLRPAH
HHHCHHHHHHHHHHHHHCCCEEEHEEECCCC
>Mature Secondary Structure
MRSRLGPCGIDSAMWATEASQEGRLGRHIHVIGIGAGDPDYLTVQAIEALNDTQVFFAMD
CCCCCCCCCCCHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEHEEHHHCCCCEEEEEEC
KGEQKSDLVALRREICSRFIRQPGYRFVELRDPKRSDRADYRDAVAEWHAARAQIWADAI
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AAELGPHGVGGFLAWGDPSLYDSTLRILDTVAGHVEFTFDVIPGITAVQALTARHRIPLN
HHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCEEEEEEHHCCHHHHHHHHHHCCCCHH
EVGEPVLITTGRQLRAHGISGSAVVMLDADCSFQRCAPETRIWWGAYLGTADELLVAGTV
HCCCCEEEECCCEEEECCCCCCEEEEEECCCCHHHCCCCCEEEEEHHHCCCCCEEEECCC
GEVGPRIAALRAQARARHGWIMDTYLLRPAH
HHHCHHHHHHHHHHHHHCCCEEEHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521 [H]