Click here to switch to the map view.

The map label for this gene is yisK [H]

Identifier: 41406979

GI number: 41406979

Start: 906563

End: 908500

Strand: Direct

Name: yisK [H]

Synonym: MAP0881

Alternate gene names: 41406979

Gene position: 906563-908500 (Clockwise)

Preceding gene: 41406978

Following gene: 41406981

Centisome position: 18.77

GC content: 70.12

Gene sequence:

>1938_bases
GTGAAATGGGTTACCTACCAAGGCGATGACGGCGAACGCGTCGGAGTGCTGCGCGACGACACCATCTACGCGATGGGTTC
GGGAGTCACGCTGCTGGACCTGATTGCGCGCGGCGCCGAGGGATTGCGGCACGCGGGGGAGGAGGCGCAGCGTTCGCCGG
CGGCGACGGTGCCGGCGGCCCGGGCGCGGTTGCTGGCGCCGATCCCGCGCCCGCCGTCGATCAGGGACTCGCTGTGCTTC
CTCGACCACATGCGCAACTGCCAGGCCGCGCTGGGCGCCGGGCGGGTCCTCGCCGACACCTGGTATCGCGTACCGGCGTT
CTACTTCGCCTGTCCGGCAACGGTTTTGGGCCCGTACGACGACGCGCCCACCGCACCCGGAAGTGCCTGGCAGGACTTCG
AATTGGAGATCGCCGCGGTGATCGGGACCGGCGGAAAGGATCTCTCCGTCGAGCAGGCCGAACAGGCCATCATCGGCTAC
ACCATCTTCAACGACTGGTCCGCGCGCGATCTGCAGCAGCTGGACAGTCAACTCGGTATCGGCCAGGCCAAGGGCAAGGA
CAGCGGCGTCACGCTAGGGCCTTACCTGGTGACACCCGACGAGCTCGAACCCTACCGCCGGAACGGCAAACTGGACCTGC
GGGTCACCGCCTCGGTCAACGACACCGTCATCGGTTCCGGGTCGACCGCCCAAATGGACTGGACCTTCGGCGAAGTCATC
TCCTATGCGTCGCGCGGCGTCACCCTGGTACCCGGTGACGTCATCGGGTCCGGGACGGTGCCCACCTGCACACTGGTCGA
GCACCTGGATCCCGCGGCGCTGGAATCATTTCCGGGCTGGCTGCACGACGGCGACGTCGTCACGCTGCGGGTCGAAGGGC
TGGGCGAGACCCGGCAAACCGTGCGCGCCAGCGGCGCGCCGCACCCGCTGGCCGCCCGGCCCAACCCGGACGCCCCGCCG
GCCGCACCGCGGGTCAACCGGGCCGCGGCGCGGGTGCCCTACACCCGCGGGCTGCACCAGGTCGGCGACCGGGTGTGGGC
ATGGACGCTGCCCGACGGGGGCTACGGCTGGAGCAATGCCGGCCTGATCGCCGGCGACGGCGCCTCGCTGCTGGTGGACA
CCCTGTTCGACCTGGCGTTGACCCGCGAAATGCTCACGGCCATGCGGCCGATCACCGCGTCGGCGCCGATCACCAAAGCG
GTGATCACGCACTCCAACGGCGACCACACGCACGGCAACCAGCTGCTCGACCCCGCGGTGCGCATCATCGCCGCGCACGG
CACCGCCGAGGAGATCGCGCACGGGATGGCGCCGGAGATGCTGGCCATGGCCCAAACCGCCGACCTGGGCCCGGTGGCCA
CCCGCTACACGCGAGAACGCTTCGGGCACTTCGACTTCAGCAACATCACGCTGCGCAACGCCGACGAGACGTTCGACCGC
AGCCTGGCCGTGGAGGTCGGTGGCCGGCGGGTCGACGTGCTGAATCTGGGGCCCGCGCACACCGCCGCCGACTCGGTGGT
GCACGTCCCCGACGCGGGGGTGCTGTTCGGCGGTGACCTGTTGTTCATCGGCTGCACCCCCATCGTGTGGGCCGGCCCGA
TCGCCAACTGGGTCGCGGCCTGCGATGCGATGATCGCGCTGGACGCGCCGACCGTGGTGCCCGGCCACGGGCCGGTCACC
GATCCGGACGGAATCCGCGCGGTGCGTGGGTATCTCGTGCACATCGCCGAACAGGCCGAGGCCGCCTACCGCAAGGGCCT
GTCGTGGTCCGAGGCCGCGGACACCATCGACCTCGGCGAGTACGCGACCTGGCTGGACGCCGAGCGGGTCGTCGTCAACG
TCTACCAGCGATACCGCGAACTCGACCCGCACACCCCGCAACTGGAAGCGATGGCCCTGCTGGTGATGCAGGCCGAATGG
CTGGCCAGACGGTCCTGA

Upstream 100 bases:

>100_bases
GCGAGGTGCGCTACAGCGAGTGGACACCGGATGACCGGCTGCGCCAATCGAGTTGGCGCGGGCTGCGGCCGGACAAGGAA
GCAAGCGAGGTGGTACGCGA

Downstream 100 bases:

>100_bases
CCGGGTGCTCGCTGCGGTCAGGACTTGATCGCCCGCACGAAGCTGAGCGTGGCGGCCGGCCCCTGCTCGGCCTCGGTGAG
TTCCGGCAGGCCCGCCGCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MKWVTYQGDDGERVGVLRDDTIYAMGSGVTLLDLIARGAEGLRHAGEEAQRSPAATVPAARARLLAPIPRPPSIRDSLCF
LDHMRNCQAALGAGRVLADTWYRVPAFYFACPATVLGPYDDAPTAPGSAWQDFELEIAAVIGTGGKDLSVEQAEQAIIGY
TIFNDWSARDLQQLDSQLGIGQAKGKDSGVTLGPYLVTPDELEPYRRNGKLDLRVTASVNDTVIGSGSTAQMDWTFGEVI
SYASRGVTLVPGDVIGSGTVPTCTLVEHLDPAALESFPGWLHDGDVVTLRVEGLGETRQTVRASGAPHPLAARPNPDAPP
AAPRVNRAAARVPYTRGLHQVGDRVWAWTLPDGGYGWSNAGLIAGDGASLLVDTLFDLALTREMLTAMRPITASAPITKA
VITHSNGDHTHGNQLLDPAVRIIAAHGTAEEIAHGMAPEMLAMAQTADLGPVATRYTRERFGHFDFSNITLRNADETFDR
SLAVEVGGRRVDVLNLGPAHTAADSVVHVPDAGVLFGGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVT
DPDGIRAVRGYLVHIAEQAEAAYRKGLSWSEAADTIDLGEYATWLDAERVVVNVYQRYRELDPHTPQLEAMALLVMQAEW
LARRS

Sequences:

>Translated_645_residues
MKWVTYQGDDGERVGVLRDDTIYAMGSGVTLLDLIARGAEGLRHAGEEAQRSPAATVPAARARLLAPIPRPPSIRDSLCF
LDHMRNCQAALGAGRVLADTWYRVPAFYFACPATVLGPYDDAPTAPGSAWQDFELEIAAVIGTGGKDLSVEQAEQAIIGY
TIFNDWSARDLQQLDSQLGIGQAKGKDSGVTLGPYLVTPDELEPYRRNGKLDLRVTASVNDTVIGSGSTAQMDWTFGEVI
SYASRGVTLVPGDVIGSGTVPTCTLVEHLDPAALESFPGWLHDGDVVTLRVEGLGETRQTVRASGAPHPLAARPNPDAPP
AAPRVNRAAARVPYTRGLHQVGDRVWAWTLPDGGYGWSNAGLIAGDGASLLVDTLFDLALTREMLTAMRPITASAPITKA
VITHSNGDHTHGNQLLDPAVRIIAAHGTAEEIAHGMAPEMLAMAQTADLGPVATRYTRERFGHFDFSNITLRNADETFDR
SLAVEVGGRRVDVLNLGPAHTAADSVVHVPDAGVLFGGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVT
DPDGIRAVRGYLVHIAEQAEAAYRKGLSWSEAADTIDLGEYATWLDAERVVVNVYQRYRELDPHTPQLEAMALLVMQAEW
LARRS
>Mature_645_residues
MKWVTYQGDDGERVGVLRDDTIYAMGSGVTLLDLIARGAEGLRHAGEEAQRSPAATVPAARARLLAPIPRPPSIRDSLCF
LDHMRNCQAALGAGRVLADTWYRVPAFYFACPATVLGPYDDAPTAPGSAWQDFELEIAAVIGTGGKDLSVEQAEQAIIGY
TIFNDWSARDLQQLDSQLGIGQAKGKDSGVTLGPYLVTPDELEPYRRNGKLDLRVTASVNDTVIGSGSTAQMDWTFGEVI
SYASRGVTLVPGDVIGSGTVPTCTLVEHLDPAALESFPGWLHDGDVVTLRVEGLGETRQTVRASGAPHPLAARPNPDAPP
AAPRVNRAAARVPYTRGLHQVGDRVWAWTLPDGGYGWSNAGLIAGDGASLLVDTLFDLALTREMLTAMRPITASAPITKA
VITHSNGDHTHGNQLLDPAVRIIAAHGTAEEIAHGMAPEMLAMAQTADLGPVATRYTRERFGHFDFSNITLRNADETFDR
SLAVEVGGRRVDVLNLGPAHTAADSVVHVPDAGVLFGGDLLFIGCTPIVWAGPIANWVAACDAMIALDAPTVVPGHGPVT
DPDGIRAVRGYLVHIAEQAEAAYRKGLSWSEAADTIDLGEYATWLDAERVVVNVYQRYRELDPHTPQLEAMALLVMQAEW
LARRS

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=252, Percent_Identity=30.1587301587302, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI40786394, Length=254, Percent_Identity=29.9212598425197, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI4557587, Length=177, Percent_Identity=30.5084745762712, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28572127, Length=311, Percent_Identity=27.0096463022508, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24657182, Length=156, Percent_Identity=28.8461538461538, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 68996; Mature: 68996

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWVTYQGDDGERVGVLRDDTIYAMGSGVTLLDLIARGAEGLRHAGEEAQRSPAATVPAA
CCEEEEECCCCCEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHH
RARLLAPIPRPPSIRDSLCFLDHMRNCQAALGAGRVLADTWYRVPAFYFACPATVLGPYD
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHCCCCC
DAPTAPGSAWQDFELEIAAVIGTGGKDLSVEQAEQAIIGYTIFNDWSARDLQQLDSQLGI
CCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHCEEEEEEEECCCCHHHHHHHHHHCCC
GQAKGKDSGVTLGPYLVTPDELEPYRRNGKLDLRVTASVNDTVIGSGSTAQMDWTFGEVI
CCCCCCCCCEEECCEEECCCCCCHHHHCCCEEEEEEECCCCEEECCCCCEEECCCHHHHH
SYASRGVTLVPGDVIGSGTVPTCTLVEHLDPAALESFPGWLHDGDVVTLRVEGLGETRQT
HHHHCCCEEECCCCCCCCCCCHHHHHHHCCHHHHHHCCCCCCCCCEEEEEECCCCHHHHH
VRASGAPHPLAARPNPDAPPAAPRVNRAAARVPYTRGLHQVGDRVWAWTLPDGGYGWSNA
HHHCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHCCEEEEEECCCCCCCCCCC
GLIAGDGASLLVDTLFDLALTREMLTAMRPITASAPITKAVITHSNGDHTHGNQLLDPAV
CEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHH
RIIAAHGTAEEIAHGMAPEMLAMAQTADLGPVATRYTRERFGHFDFSNITLRNADETFDR
HEEECCCCHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEECCCHHHCC
SLAVEVGGRRVDVLNLGPAHTAADSVVHVPDAGVLFGGDLLFIGCTPIVWAGPIANWVAA
EEEEEECCEEEEEEECCCCCCCCCCEEECCCCCEEECCCEEEEECCCCEECCHHHHHHHH
CDAMIALDAPTVVPGHGPVTDPDGIRAVRGYLVHIAEQAEAAYRKGLSWSEAADTIDLGE
HHHHEEECCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEECCH
YATWLDAERVVVNVYQRYRELDPHTPQLEAMALLVMQAEWLARRS
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKWVTYQGDDGERVGVLRDDTIYAMGSGVTLLDLIARGAEGLRHAGEEAQRSPAATVPAA
CCEEEEECCCCCEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHH
RARLLAPIPRPPSIRDSLCFLDHMRNCQAALGAGRVLADTWYRVPAFYFACPATVLGPYD
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHCCCCC
DAPTAPGSAWQDFELEIAAVIGTGGKDLSVEQAEQAIIGYTIFNDWSARDLQQLDSQLGI
CCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHCEEEEEEEECCCCHHHHHHHHHHCCC
GQAKGKDSGVTLGPYLVTPDELEPYRRNGKLDLRVTASVNDTVIGSGSTAQMDWTFGEVI
CCCCCCCCCEEECCEEECCCCCCHHHHCCCEEEEEEECCCCEEECCCCCEEECCCHHHHH
SYASRGVTLVPGDVIGSGTVPTCTLVEHLDPAALESFPGWLHDGDVVTLRVEGLGETRQT
HHHHCCCEEECCCCCCCCCCCHHHHHHHCCHHHHHHCCCCCCCCCEEEEEECCCCHHHHH
VRASGAPHPLAARPNPDAPPAAPRVNRAAARVPYTRGLHQVGDRVWAWTLPDGGYGWSNA
HHHCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHCCEEEEEECCCCCCCCCCC
GLIAGDGASLLVDTLFDLALTREMLTAMRPITASAPITKAVITHSNGDHTHGNQLLDPAV
CEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHH
RIIAAHGTAEEIAHGMAPEMLAMAQTADLGPVATRYTRERFGHFDFSNITLRNADETFDR
HEEECCCCHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEECCCHHHCC
SLAVEVGGRRVDVLNLGPAHTAADSVVHVPDAGVLFGGDLLFIGCTPIVWAGPIANWVAA
EEEEEECCEEEEEEECCCCCCCCCCEEECCCCCEEECCCEEEEECCCCEECCHHHHHHHH
CDAMIALDAPTVVPGHGPVTDPDGIRAVRGYLVHIAEQAEAAYRKGLSWSEAADTIDLGE
HHHHEEECCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEECCH
YATWLDAERVVVNVYQRYRELDPHTPQLEAMALLVMQAEWLARRS
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377 [H]