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The map label for this gene is 41406978

Identifier: 41406978

GI number: 41406978

Start: 904272

End: 906566

Strand: Direct

Name: 41406978

Synonym: MAP0880

Alternate gene names: NA

Gene position: 904272-906566 (Clockwise)

Preceding gene: 41406972

Following gene: 41406979

Centisome position: 18.72

GC content: 67.84

Gene sequence:

>2295_bases
ATGAACGCGCCGCGCGCTTGGCCCGCTGAGCCGACAGCGACGCCGCGGGTGAAACTGACCAACGCCGACAAGGTGCTCTA
TCCCGCGACGGGAACCACCAAAGCCGACGTCTTCGACTACTACACGCGGATCGCCGACGTGATGATCCCGCACATCGCCG
GGCGTCCGGTCACCCGGAAGCGCTGGCCCAACGGCGTCGATCAGGAATCGTTCTTCGAAAAGCAGCTGGCCTCCTCGGCA
CCGGACTGGCTGCCGCGCGCCAGCGTGACCCACCGATCCGGCACGACGACCTATCCGATCATCGACAGCGCCACCGGCCT
GGCCTGGATCGCCCAGCAGGCGGCGCTGGAGGTGCACGTGCCGCAGTGGCGGTTCGTCGCGGAGTGGACCCGAAGCCGGG
CCGAAGAACTCAAACCCGGCCCGGCGACTCGACTGGTGTTCGACCTCGACCCGGGCGAAGGCGTGACGATGGCCCAGCTC
GCCGAGGTGGCGCGCGCCGTCCGCGACCTGATCGATGGGATCGGGCTGCAGACGTTTCCGCTCACCAGCGGCAGCAAGGG
ACTGCACCTGTACACGCCGCTGACGGAGCCGGTGAGCAGCAAAGGCGCCACCGTGCTGGCCAAACGCGTTGCGCAGCAAC
TGGAAAAGACCATGCCGAAGCTGGTCACCTCGACCATGACCAAGAGCCTGCGGGCGGGAAAGATCTTTGTGGACTGGAGC
CAGAACAACGGCTCCAAGACGACCATCGCGCCCTATTCGCTGCGCGGGCGCGACCACCCCACCGTCGCCGCGCCGCGCAC
CTGGGACGAACTCGACGACCCGGCGCTGCGTCACCTGCGCTACGACGAAGTGCTGACCCGGGTCGCCCGCGACGGTGACC
TGCTCGCCGAGCTGGACGACAACCAGACACCGGTGCCGGACCGCCTGACCAAATACCGCAGCATGCGCGACGCCTCCAAA
ACACCCGAGCCGGTTCCGGACGCGAAACCTGCTGCGGGACAAGGTAATACCTTCGTCATCCAAGAGCACCACGCCCGGCG
GCTGCACTACGACTTCCGGCTGGAGCGCGACGGGGTGCTGGTGTCCTGGGCGGTGCCGAAGAACCTGCCCGACACCCCCG
CGGTGAATCACCTGGCCGTGCACACCGAGGATCACCCGCTGGAATACGGCGGGTTCGAGGGCGTCATCCCCAAAGGCGAA
TACGGGGCGGGCAGGGTGGTCATCTGGGACTCCGGAACCTATGACGCCGAGAAGTTCCAGGACGACGAGGTGATCGTCAA
CCTGCACGGCCGCAAGATCTCCGGGCGCTACGCGCTGATCCAGACCCAGGGCGACCAATGGCTGGCGCACCGGATGAAGG
ACCAGAACGTCTTCGAGTTCGACACGATCGCCCCGATGCTCGCCACCCACGGTTCGGTGTCGGCGCTCAAGGCGAGCCAG
TGGGCGTTCGAGGGCAAATGGGACGGCTACCGGCTACTGGTCGAGGCCGACCACGGCACCCTGCGGGTGCGGTCCCGGCG
CGGTCGCGAAGTCACCGGCGAGTACCGCGAATTACGCTCGCTGGCAAAGGCTCTCGAGGAGCACCACGCGGTGCTCGACG
GCGAGGCCGTGGTGCTGGACAAGCGCGGCGTGCCCAACTTCCACGAGATGCAAAACCGCGGCAAGAGCGCGCGGGTCGAA
TTCTGGGCGTTCGACCTGCTCTACCTCGACGGCCGCTCGCTGCTGCGGGCCCGCTACCGCGACCGGCGAAAACTGTTGGA
AATGCTGGCCTCCGGCGGTGCTCTCACCGTTCCCGAGCTGCTGCCCGGCGACGGCGACCAAGCGCTGCGGCAGTCCGCCG
AGCGCGGTTGGGAGGGCGTGATCGCCAAGCGGCGCGACTCCACCTATCAGCCCGGCCGGCGCTCGTCCTCCTGGATCAAG
GACAAGCATTGGAACACCCAGGAAGTCGTGATCGGCGGCTGGAAGGCCGGGGAAGGCGGACGCAGCAGCGGCATCGGTTC
CCTGCTGATGGGCATTCCGGGCCCGGGCGGCCTGCACTTCGCCGGCCGCGTCGGCACCGGGTTCACCGAACGCGACCTAG
CCAACTTGAAGAAGACGCTGGCCCCGCTGCGCACCGACCAATCGCCCTTCGATGCGCCGCTTCCCCGCAGCGAGGCCAAG
GGCGTCACGTTCGTCGAGCCGGTGCTGGTGGGCGAGGTGCGCTACAGCGAGTGGACACCGGATGACCGGCTGCGCCAATC
GAGTTGGCGCGGGCTGCGGCCGGACAAGGAAGCAAGCGAGGTGGTACGCGAGTGA

Upstream 100 bases:

>100_bases
GGTCACCGGTACCGGCGTCGCCGCCCCGCACCTTGCGGCTCGCGTGTCGGCCGCCGATTGCACCCTGGCGTCGGCGGCAC
CGGCGCGTAGGTTTAGCAGC

Downstream 100 bases:

>100_bases
AATGGGTTACCTACCAAGGCGATGACGGCGAACGCGTCGGAGTGCTGCGCGACGACACCATCTACGCGATGGGTTCGGGA
GTCACGCTGCTGGACCTGAT

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 764; Mature: 764

Protein sequence:

>764_residues
MNAPRAWPAEPTATPRVKLTNADKVLYPATGTTKADVFDYYTRIADVMIPHIAGRPVTRKRWPNGVDQESFFEKQLASSA
PDWLPRASVTHRSGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEWTRSRAEELKPGPATRLVFDLDPGEGVTMAQL
AEVARAVRDLIDGIGLQTFPLTSGSKGLHLYTPLTEPVSSKGATVLAKRVAQQLEKTMPKLVTSTMTKSLRAGKIFVDWS
QNNGSKTTIAPYSLRGRDHPTVAAPRTWDELDDPALRHLRYDEVLTRVARDGDLLAELDDNQTPVPDRLTKYRSMRDASK
TPEPVPDAKPAAGQGNTFVIQEHHARRLHYDFRLERDGVLVSWAVPKNLPDTPAVNHLAVHTEDHPLEYGGFEGVIPKGE
YGAGRVVIWDSGTYDAEKFQDDEVIVNLHGRKISGRYALIQTQGDQWLAHRMKDQNVFEFDTIAPMLATHGSVSALKASQ
WAFEGKWDGYRLLVEADHGTLRVRSRRGREVTGEYRELRSLAKALEEHHAVLDGEAVVLDKRGVPNFHEMQNRGKSARVE
FWAFDLLYLDGRSLLRARYRDRRKLLEMLASGGALTVPELLPGDGDQALRQSAERGWEGVIAKRRDSTYQPGRRSSSWIK
DKHWNTQEVVIGGWKAGEGGRSSGIGSLLMGIPGPGGLHFAGRVGTGFTERDLANLKKTLAPLRTDQSPFDAPLPRSEAK
GVTFVEPVLVGEVRYSEWTPDDRLRQSSWRGLRPDKEASEVVRE

Sequences:

>Translated_764_residues
MNAPRAWPAEPTATPRVKLTNADKVLYPATGTTKADVFDYYTRIADVMIPHIAGRPVTRKRWPNGVDQESFFEKQLASSA
PDWLPRASVTHRSGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEWTRSRAEELKPGPATRLVFDLDPGEGVTMAQL
AEVARAVRDLIDGIGLQTFPLTSGSKGLHLYTPLTEPVSSKGATVLAKRVAQQLEKTMPKLVTSTMTKSLRAGKIFVDWS
QNNGSKTTIAPYSLRGRDHPTVAAPRTWDELDDPALRHLRYDEVLTRVARDGDLLAELDDNQTPVPDRLTKYRSMRDASK
TPEPVPDAKPAAGQGNTFVIQEHHARRLHYDFRLERDGVLVSWAVPKNLPDTPAVNHLAVHTEDHPLEYGGFEGVIPKGE
YGAGRVVIWDSGTYDAEKFQDDEVIVNLHGRKISGRYALIQTQGDQWLAHRMKDQNVFEFDTIAPMLATHGSVSALKASQ
WAFEGKWDGYRLLVEADHGTLRVRSRRGREVTGEYRELRSLAKALEEHHAVLDGEAVVLDKRGVPNFHEMQNRGKSARVE
FWAFDLLYLDGRSLLRARYRDRRKLLEMLASGGALTVPELLPGDGDQALRQSAERGWEGVIAKRRDSTYQPGRRSSSWIK
DKHWNTQEVVIGGWKAGEGGRSSGIGSLLMGIPGPGGLHFAGRVGTGFTERDLANLKKTLAPLRTDQSPFDAPLPRSEAK
GVTFVEPVLVGEVRYSEWTPDDRLRQSSWRGLRPDKEASEVVRE
>Mature_764_residues
MNAPRAWPAEPTATPRVKLTNADKVLYPATGTTKADVFDYYTRIADVMIPHIAGRPVTRKRWPNGVDQESFFEKQLASSA
PDWLPRASVTHRSGTTTYPIIDSATGLAWIAQQAALEVHVPQWRFVAEWTRSRAEELKPGPATRLVFDLDPGEGVTMAQL
AEVARAVRDLIDGIGLQTFPLTSGSKGLHLYTPLTEPVSSKGATVLAKRVAQQLEKTMPKLVTSTMTKSLRAGKIFVDWS
QNNGSKTTIAPYSLRGRDHPTVAAPRTWDELDDPALRHLRYDEVLTRVARDGDLLAELDDNQTPVPDRLTKYRSMRDASK
TPEPVPDAKPAAGQGNTFVIQEHHARRLHYDFRLERDGVLVSWAVPKNLPDTPAVNHLAVHTEDHPLEYGGFEGVIPKGE
YGAGRVVIWDSGTYDAEKFQDDEVIVNLHGRKISGRYALIQTQGDQWLAHRMKDQNVFEFDTIAPMLATHGSVSALKASQ
WAFEGKWDGYRLLVEADHGTLRVRSRRGREVTGEYRELRSLAKALEEHHAVLDGEAVVLDKRGVPNFHEMQNRGKSARVE
FWAFDLLYLDGRSLLRARYRDRRKLLEMLASGGALTVPELLPGDGDQALRQSAERGWEGVIAKRRDSTYQPGRRSSSWIK
DKHWNTQEVVIGGWKAGEGGRSSGIGSLLMGIPGPGGLHFAGRVGTGFTERDLANLKKTLAPLRTDQSPFDAPLPRSEAK
GVTFVEPVLVGEVRYSEWTPDDRLRQSSWRGLRPDKEASEVVRE

Specific function: Unknown

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Homo sapiens, GI4557719, Length=276, Percent_Identity=28.6231884057971, Blast_Score=80, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71985269, Length=330, Percent_Identity=27.8787878787879, Blast_Score=87, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6320038, Length=283, Percent_Identity=24.7349823321555, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24762424, Length=265, Percent_Identity=27.9245283018868, Blast_Score=76, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR002755
- InterPro:   IPR014144
- InterPro:   IPR014145
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF01896 DNA_primase_S [H]

EC number: NA

Molecular weight: Translated: 85152; Mature: 85152

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPRAWPAEPTATPRVKLTNADKVLYPATGTTKADVFDYYTRIADVMIPHIAGRPVTRK
CCCCCCCCCCCCCCCEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHH
RWPNGVDQESFFEKQLASSAPDWLPRASVTHRSGTTTYPIIDSATGLAWIAQQAALEVHV
CCCCCCCHHHHHHHHHHHCCCCCCCCCCEECCCCCEEECEECCCCHHHHHHHHHHEEEEC
PQWRFVAEWTRSRAEELKPGPATRLVFDLDPGEGVTMAQLAEVARAVRDLIDGIGLQTFP
CCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEE
LTSGSKGLHLYTPLTEPVSSKGATVLAKRVAQQLEKTMPKLVTSTMTKSLRAGKIFVDWS
CCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
QNNGSKTTIAPYSLRGRDHPTVAAPRTWDELDDPALRHLRYDEVLTRVARDGDLLAELDD
CCCCCEEEEECEEECCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCC
NQTPVPDRLTKYRSMRDASKTPEPVPDAKPAAGQGNTFVIQEHHARRLHYDFRLERDGVL
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEECCCEE
VSWAVPKNLPDTPAVNHLAVHTEDHPLEYGGFEGVIPKGEYGAGRVVIWDSGTYDAEKFQ
EEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHCC
DDEVIVNLHGRKISGRYALIQTQGDQWLAHRMKDQNVFEFDTIAPMLATHGSVSALKASQ
CCCEEEEECCEEECCCEEEEEECCHHHHHHHHCCCCCEEHHHHHHHHHCCCCHHHHHHHH
WAFEGKWDGYRLLVEADHGTLRVRSRRGREVTGEYRELRSLAKALEEHHAVLDGEAVVLD
CCCCCCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHEECCCEEEEE
KRGVPNFHEMQNRGKSARVEFWAFDLLYLDGRSLLRARYRDRRKLLEMLASGGALTVPEL
CCCCCCHHHHHCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEECHHH
LPGDGDQALRQSAERGWEGVIAKRRDSTYQPGRRSSSWIKDKHWNTQEVVIGGWKAGEGG
CCCCCHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCEEEEEEEECCCCC
RSSGIGSLLMGIPGPGGLHFAGRVGTGFTERDLANLKKTLAPLRTDQSPFDAPLPRSEAK
CCCCCHHHEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GVTFVEPVLVGEVRYSEWTPDDRLRQSSWRGLRPDKEASEVVRE
CCEEECCEEECCEECCCCCCHHHHHHHHCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MNAPRAWPAEPTATPRVKLTNADKVLYPATGTTKADVFDYYTRIADVMIPHIAGRPVTRK
CCCCCCCCCCCCCCCEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHH
RWPNGVDQESFFEKQLASSAPDWLPRASVTHRSGTTTYPIIDSATGLAWIAQQAALEVHV
CCCCCCCHHHHHHHHHHHCCCCCCCCCCEECCCCCEEECEECCCCHHHHHHHHHHEEEEC
PQWRFVAEWTRSRAEELKPGPATRLVFDLDPGEGVTMAQLAEVARAVRDLIDGIGLQTFP
CCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEE
LTSGSKGLHLYTPLTEPVSSKGATVLAKRVAQQLEKTMPKLVTSTMTKSLRAGKIFVDWS
CCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
QNNGSKTTIAPYSLRGRDHPTVAAPRTWDELDDPALRHLRYDEVLTRVARDGDLLAELDD
CCCCCEEEEECEEECCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCC
NQTPVPDRLTKYRSMRDASKTPEPVPDAKPAAGQGNTFVIQEHHARRLHYDFRLERDGVL
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEECCCEE
VSWAVPKNLPDTPAVNHLAVHTEDHPLEYGGFEGVIPKGEYGAGRVVIWDSGTYDAEKFQ
EEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHCC
DDEVIVNLHGRKISGRYALIQTQGDQWLAHRMKDQNVFEFDTIAPMLATHGSVSALKASQ
CCCEEEEECCEEECCCEEEEEECCHHHHHHHHCCCCCEEHHHHHHHHHCCCCHHHHHHHH
WAFEGKWDGYRLLVEADHGTLRVRSRRGREVTGEYRELRSLAKALEEHHAVLDGEAVVLD
CCCCCCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHEECCCEEEEE
KRGVPNFHEMQNRGKSARVEFWAFDLLYLDGRSLLRARYRDRRKLLEMLASGGALTVPEL
CCCCCCHHHHHCCCCCCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEECHHH
LPGDGDQALRQSAERGWEGVIAKRRDSTYQPGRRSSSWIKDKHWNTQEVVIGGWKAGEGG
CCCCCHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCEEEEEEEECCCCC
RSSGIGSLLMGIPGPGGLHFAGRVGTGFTERDLANLKKTLAPLRTDQSPFDAPLPRSEAK
CCCCCHHHEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GVTFVEPVLVGEVRYSEWTPDDRLRQSSWRGLRPDKEASEVVRE
CCEEECCEEECCEECCCCCCHHHHHHHHCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]