| Definition | Geobacter sulfurreducens PCA chromosome, complete genome. |
|---|---|
| Accession | NC_002939 |
| Length | 3,814,139 |
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The map label for this gene is pleD [H]
Identifier: 39997726
GI number: 39997726
Start: 2902943
End: 2904178
Strand: Direct
Name: pleD [H]
Synonym: GSU2632
Alternate gene names: 39997726
Gene position: 2902943-2904178 (Clockwise)
Preceding gene: 39997725
Following gene: 39997727
Centisome position: 76.11
GC content: 65.37
Gene sequence:
>1236_bases GTGAACACCCTGACGGCAAAACATTTCATCATCTTCGTGATTCCCGCTGCGCTTCTGGCGGCAACCTTCTGGTTCATGCC CCGGGTGCCGGAGCTGCCCCCGGCACGACTTGAGCTACTCCCCCATCTCCCCTATCCGGCGATTGCCCTCGGCGCCATTC TCTCCATCCACTTCCACCGGGGACGGGCATTGTTCGTCTTTTTACTGCTGGCTGTCTCGTACTGGAGCTTTCAGGGGAAT GCGACGGAACTCCCCAGGGGAATCGAGGCCACGGTGCTCTACCAGGCCGTCACCCTGCTCGTGCCGCTCAACATCGCCCT GTTCTCGCTCATGCGGGAACGCGGAATCGTTACGGTAGCGGGGCGAATCCGCTTCGCATTCCTGGGGCTCCAGGCACTGC TCGTCTGGTGGGCCATGACACCGGGGCACGTGGCGGTCCAGCAGCTGCTGGCGGGTCATTTGAGCGCTGCCGGTGTGGTC GCCGGGTCTCCTCTCCCACCTCCGGCCATCCCGGCAATAGTCCTCTCGGGCTTGCTGGTGGCGGCGCGGGCAGGACTGAA ACAGTCTCCCGTGGACAGCGCGTTCCTGGGGGTCCTGGTGGCCTTTGCCGTGGCGGGCAACGGCATCGCCCACCCCCATG TCACCCCGGTCTTCATGACTGCCGCGGCAGTTATCCTCTCACTCGGCGTGCTCAAGGATTCCTACAACATGGCGTTCCGG GACGAGTTGACGGGTCTCCCGTCCCGCCGGGCGCTCAGCGAGCAGCTTACCTGGCTGGGCCGGCGCTACAGCGTTGCCAT GGTTGACGTCGACCACTTCAAAAAGTTCAACGACACCTACGGACACGACGTGGGGGATCAGGTGCTCCGGCTGGTGGCGG CAAAACTGCGCGGCGTGGGAGGTGGGGGCAAGGCCTACCGCTACGGCGGCGAAGAGTTCACCATCCTTTTCCCCCATCGG TCGCGGGAAGAGGTCCTCGGCCGCCTGGAAGAGTTGCGACGGGCCATCGCCGATTACCAGATGCGCCTGCGCTCCTCGGA CCGGCCCGCCTCAAGCAGGGAGGGAAAGAGGCAGCGCTCCGGCATGCCCCAAGGGCGCGGCTGCGTCTCGGTAACCATCA GCATCGGCGTGGCTGAAAGCAGCAGCGAACTTCGCCGGCCCGCCGATGTCATCAAGGCGGCCGACGACGCCCTCTACCGC GCCAAGGGGCGCGGCCGCAACCAGGTGAGCACCTGA
Upstream 100 bases:
>100_bases GATAAAAATTATCGGCGAGTGACCCTGCGTCGGCCAAAAGATTGCATATTTCTCATCCTGTCCGATCCCTCTGACCACCT GTCCAAGGAGCAGCGCCCGG
Downstream 100 bases:
>100_bases CCCGGCAGAAGCCCCGGCTCTCCGCCTGCACCTGTCCTCCCCCGTGATTGCATTCTTCCGGCCGGCCGCTATACTTTTTC CTTGTCACCCCACATCATCA
Product: GGDEF domain-containing protein
Products: NA
Alternate protein names: Stalked cell differentiation-controlling protein; Diguanylate cyclase; DGC; Diguanylate kinase [H]
Number of amino acids: Translated: 411; Mature: 411
Protein sequence:
>411_residues MNTLTAKHFIIFVIPAALLAATFWFMPRVPELPPARLELLPHLPYPAIALGAILSIHFHRGRALFVFLLLAVSYWSFQGN ATELPRGIEATVLYQAVTLLVPLNIALFSLMRERGIVTVAGRIRFAFLGLQALLVWWAMTPGHVAVQQLLAGHLSAAGVV AGSPLPPPAIPAIVLSGLLVAARAGLKQSPVDSAFLGVLVAFAVAGNGIAHPHVTPVFMTAAAVILSLGVLKDSYNMAFR DELTGLPSRRALSEQLTWLGRRYSVAMVDVDHFKKFNDTYGHDVGDQVLRLVAAKLRGVGGGGKAYRYGGEEFTILFPHR SREEVLGRLEELRRAIADYQMRLRSSDRPASSREGKRQRSGMPQGRGCVSVTISIGVAESSSELRRPADVIKAADDALYR AKGRGRNQVST
Sequences:
>Translated_411_residues MNTLTAKHFIIFVIPAALLAATFWFMPRVPELPPARLELLPHLPYPAIALGAILSIHFHRGRALFVFLLLAVSYWSFQGN ATELPRGIEATVLYQAVTLLVPLNIALFSLMRERGIVTVAGRIRFAFLGLQALLVWWAMTPGHVAVQQLLAGHLSAAGVV AGSPLPPPAIPAIVLSGLLVAARAGLKQSPVDSAFLGVLVAFAVAGNGIAHPHVTPVFMTAAAVILSLGVLKDSYNMAFR DELTGLPSRRALSEQLTWLGRRYSVAMVDVDHFKKFNDTYGHDVGDQVLRLVAAKLRGVGGGGKAYRYGGEEFTILFPHR SREEVLGRLEELRRAIADYQMRLRSSDRPASSREGKRQRSGMPQGRGCVSVTISIGVAESSSELRRPADVIKAADDALYR AKGRGRNQVST >Mature_411_residues MNTLTAKHFIIFVIPAALLAATFWFMPRVPELPPARLELLPHLPYPAIALGAILSIHFHRGRALFVFLLLAVSYWSFQGN ATELPRGIEATVLYQAVTLLVPLNIALFSLMRERGIVTVAGRIRFAFLGLQALLVWWAMTPGHVAVQQLLAGHLSAAGVV AGSPLPPPAIPAIVLSGLLVAARAGLKQSPVDSAFLGVLVAFAVAGNGIAHPHVTPVFMTAAAVILSLGVLKDSYNMAFR DELTGLPSRRALSEQLTWLGRRYSVAMVDVDHFKKFNDTYGHDVGDQVLRLVAAKLRGVGGGGKAYRYGGEEFTILFPHR SREEVLGRLEELRRAIADYQMRLRSSDRPASSREGKRQRSGMPQGRGCVSVTISIGVAESSSELRRPADVIKAADDALYR AKGRGRNQVST
Specific function: Catalyzes the condensation of two GTP molecules to the cyclic dinucleotide di-GMP (c-di-GMP), which acts as a secondary messenger [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm. Note=Phosphorylated PleD localizes to the differentiating pole [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 response regulatory domains [H]
Homologues:
Organism=Escherichia coli, GI1787262, Length=185, Percent_Identity=34.0540540540541, Blast_Score=94, Evalue=2e-20, Organism=Escherichia coli, GI87081881, Length=180, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=2e-18, Organism=Escherichia coli, GI1787056, Length=198, Percent_Identity=32.8282828282828, Blast_Score=86, Evalue=6e-18, Organism=Escherichia coli, GI145693134, Length=150, Percent_Identity=34, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI1787802, Length=214, Percent_Identity=31.3084112149533, Blast_Score=76, Evalue=4e-15, Organism=Escherichia coli, GI1786584, Length=185, Percent_Identity=29.1891891891892, Blast_Score=76, Evalue=5e-15, Organism=Escherichia coli, GI1787816, Length=202, Percent_Identity=32.1782178217822, Blast_Score=75, Evalue=7e-15, Organism=Escherichia coli, GI87082007, Length=199, Percent_Identity=30.1507537688442, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI87081977, Length=107, Percent_Identity=32.7102803738318, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1787541, Length=178, Percent_Identity=30.8988764044944, Blast_Score=63, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001054 - InterPro: IPR011006 - InterPro: IPR000160 - InterPro: IPR001789 [H]
Pfam domain/function: PF00990 GGDEF; PF00072 Response_reg [H]
EC number: =2.7.7.65 [H]
Molecular weight: Translated: 44595; Mature: 44595
Theoretical pI: Translated: 10.80; Mature: 10.80
Prosite motif: PS50887 GGDEF
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNTLTAKHFIIFVIPAALLAATFWFMPRVPELPPARLELLPHLPYPAIALGAILSIHFHR CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHCC GRALFVFLLLAVSYWSFQGNATELPRGIEATVLYQAVTLLVPLNIALFSLMRERGIVTVA CHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEH GRIRFAFLGLQALLVWWAMTPGHVAVQQLLAGHLSAAGVVAGSPLPPPAIPAIVLSGLLV HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHH AARAGLKQSPVDSAFLGVLVAFAVAGNGIAHPHVTPVFMTAAAVILSLGVLKDSYNMAFR HHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH DELTGLPSRRALSEQLTWLGRRYSVAMVDVDHFKKFNDTYGHDVGDQVLRLVAAKLRGVG HHHCCCCCHHHHHHHHHHHCCCEEEEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC GGGKAYRYGGEEFTILFPHRSREEVLGRLEELRRAIADYQMRLRSSDRPASSREGKRQRS CCCCEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHC GMPQGRGCVSVTISIGVAESSSELRRPADVIKAADDALYRAKGRGRNQVST CCCCCCCEEEEEEEEEECCCHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCC >Mature Secondary Structure MNTLTAKHFIIFVIPAALLAATFWFMPRVPELPPARLELLPHLPYPAIALGAILSIHFHR CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHCC GRALFVFLLLAVSYWSFQGNATELPRGIEATVLYQAVTLLVPLNIALFSLMRERGIVTVA CHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEH GRIRFAFLGLQALLVWWAMTPGHVAVQQLLAGHLSAAGVVAGSPLPPPAIPAIVLSGLLV HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHH AARAGLKQSPVDSAFLGVLVAFAVAGNGIAHPHVTPVFMTAAAVILSLGVLKDSYNMAFR HHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH DELTGLPSRRALSEQLTWLGRRYSVAMVDVDHFKKFNDTYGHDVGDQVLRLVAAKLRGVG HHHCCCCCHHHHHHHHHHHCCCEEEEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC GGGKAYRYGGEEFTILFPHRSREEVLGRLEELRRAIADYQMRLRSSDRPASSREGKRQRS CCCCEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHC GMPQGRGCVSVTISIGVAESSSELRRPADVIKAADDALYRAKGRGRNQVST CCCCCCCEEEEEEEEEECCCHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA