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The map label for this gene is ihfA-2 [H]

Identifier: 39997218

GI number: 39997218

Start: 2339126

End: 2339401

Strand: Direct

Name: ihfA-2 [H]

Synonym: GSU2120

Alternate gene names: 39997218

Gene position: 2339126-2339401 (Clockwise)

Preceding gene: 39997217

Following gene: 39997219

Centisome position: 61.33

GC content: 41.3

Gene sequence:

>276_bases
ATGACTAAGGCAGATATTGTTGAAAGAGTTTCCGACCGGTGTGGAATTTCGAAGAAAGATTCCATTGAAATGGTCGAGTT
GGTTTTCAGCATTCTGAAGAACACCCTTGAGATTGGAGAGGATATAAAGATATCCGGCTTCGGGAAATTTGAAATTAAAA
ACAAGCACGCCCGCAAAGGCAGGAACCCTCAAACAGGTGATGCCATTACCATTGAGGCCAGAAGAATTCTAACGTTCAAA
CCGAGCACCATTCTGAAAAACAACATAAACTCTTAA

Upstream 100 bases:

>100_bases
CACCTTGAGAATCTCTATCAACATAGAGTAACTTTGTCCCCTCTCCCCTCCCCCGAACCGGGGGAGGGGTTTCAATCATC
TTCTGGTAAACGGAGCAATA

Downstream 100 bases:

>100_bases
TAGCACCATCACGCCCCAAGTCGTCCAAAACTTACAACTGCCCCGCTCACACCTGCCCCCCCTATAGATTATAGTCGTAG
GGGGAATCATGCGCTTCGCC

Product: integration host factor subunit alpha

Products: NA

Alternate protein names: IHF-alpha [H]

Number of amino acids: Translated: 91; Mature: 90

Protein sequence:

>91_residues
MTKADIVERVSDRCGISKKDSIEMVELVFSILKNTLEIGEDIKISGFGKFEIKNKHARKGRNPQTGDAITIEARRILTFK
PSTILKNNINS

Sequences:

>Translated_91_residues
MTKADIVERVSDRCGISKKDSIEMVELVFSILKNTLEIGEDIKISGFGKFEIKNKHARKGRNPQTGDAITIEARRILTFK
PSTILKNNINS
>Mature_90_residues
TKADIVERVSDRCGISKKDSIEMVELVFSILKNTLEIGEDIKISGFGKFEIKNKHARKGRNPQTGDAITIEARRILTFKP
STILKNNINS

Specific function: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. It is necessary for normal cell growth and the production o

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1788005, Length=89, Percent_Identity=47.1910112359551, Blast_Score=97, Evalue=2e-22,
Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=4e-14,
Organism=Escherichia coli, GI1787141, Length=91, Percent_Identity=35.1648351648352, Blast_Score=65, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992
- InterPro:   IPR005684 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 10219; Mature: 10088

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKADIVERVSDRCGISKKDSIEMVELVFSILKNTLEIGEDIKISGFGKFEIKNKHARKG
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCEEEECCCHHHCC
RNPQTGDAITIEARRILTFKPSTILKNNINS
CCCCCCCEEEEEEEEEEEECCCHHHCCCCCC
>Mature Secondary Structure 
TKADIVERVSDRCGISKKDSIEMVELVFSILKNTLEIGEDIKISGFGKFEIKNKHARKG
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCEEEECCCHHHCC
RNPQTGDAITIEARRILTFKPSTILKNNINS
CCCCCCCEEEEEEEEEEEECCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11133949 [H]