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The map label for this gene is mtnN [H]

Identifier: 39996995

GI number: 39996995

Start: 2074927

End: 2075751

Strand: Direct

Name: mtnN [H]

Synonym: GSU1897

Alternate gene names: 39996995

Gene position: 2074927-2075751 (Clockwise)

Preceding gene: 39996977

Following gene: 39997002

Centisome position: 54.4

GC content: 62.42

Gene sequence:

>825_bases
ATGCCCCCCACAACCATCGGCCTCATTGCTGCCATGCCGGACGAAACCCGCCCCCTGCTGCGTCGTTTGCGTGGGGCAAC
ATTGCTTGCACAACAGCCCTTTCCCCTCTGGCGCGCACAGGTGGGTGATGCGGATATCTGGCTGGCCCAGTCGGGCATGG
GGCCGAAGCGGGCAGAATCTGTTGCGGAACGGTTTGCCGAGGTAGCCTCACCCGATGTTATGGTTTCATTCGGATTCGGA
GGCGGCGTGCTGCCGGGATTGTCGGTCGGCGACCTGGTAATGGGAACCTGGTGTCTGCACTATGACGGAAGGGATTTCAC
CCTTGTAGCCGGGATAGACGCCCCCCTCGCTTGCAGTGTCATGAAGGCCCTGGCACAGCGCACCTCCCTCGCGGTGACCG
CCGGCACCGTCATCACCTCCGGGGCAATCCTCGCCAAACATCTTGTCGCGCCGCTTATTCCGGCCGCGGTAACATCACCG
GTGCTTGACATGGAAACAGCCGCCGTGGCCAGCATTTCCGCGCAACGCGGTATCCCGCTCCTGGCACTGCGGGCCATTAC
CGACGATGCGGCAGAAGAGTTCGGCTTTTCACTGGACGAATTTACCGATGCCGAGCTGAATATCAAGCCGTACCGGGTCG
TGACCACCTTGCTCCGAAAGCCTTGGATCATGCCGCAGCTCATAAGACTAGCGCGCTCGTCGAAGCGGGCCGGCGAACTG
CTGGCCTCGGCCGTCATCGAACTCGTCGAGGTGCTGCCTGCCACAACCCGCTGTACCCCCTCCTACTCTTTTGCGCAGCG
GCCCGAGACGGCGGACCAGGGATAA

Upstream 100 bases:

>100_bases
GCTACCGCAAAGGCAGGGACGTGTCAAGGAGTGAAATGCGTTGCCCGGGGCGCATCAGCTCTGATAGAGTGCCGTCATCC
CCCTCATGCGGAGACCGGTC

Downstream 100 bases:

>100_bases
TCCCGCAGATGTTCGGCCAGTTCCTCCTTCCGGTAGCGGTTGGTTCGGCGCACAATAGTAACAATCGCTATGGAGCCCGC
CAGGACGTAGATGAGTATCC

Product: MTA/SAH nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MPPTTIGLIAAMPDETRPLLRRLRGATLLAQQPFPLWRAQVGDADIWLAQSGMGPKRAESVAERFAEVASPDVMVSFGFG
GGVLPGLSVGDLVMGTWCLHYDGRDFTLVAGIDAPLACSVMKALAQRTSLAVTAGTVITSGAILAKHLVAPLIPAAVTSP
VLDMETAAVASISAQRGIPLLALRAITDDAAEEFGFSLDEFTDAELNIKPYRVVTTLLRKPWIMPQLIRLARSSKRAGEL
LASAVIELVEVLPATTRCTPSYSFAQRPETADQG

Sequences:

>Translated_274_residues
MPPTTIGLIAAMPDETRPLLRRLRGATLLAQQPFPLWRAQVGDADIWLAQSGMGPKRAESVAERFAEVASPDVMVSFGFG
GGVLPGLSVGDLVMGTWCLHYDGRDFTLVAGIDAPLACSVMKALAQRTSLAVTAGTVITSGAILAKHLVAPLIPAAVTSP
VLDMETAAVASISAQRGIPLLALRAITDDAAEEFGFSLDEFTDAELNIKPYRVVTTLLRKPWIMPQLIRLARSSKRAGEL
LASAVIELVEVLPATTRCTPSYSFAQRPETADQG
>Mature_273_residues
PPTTIGLIAAMPDETRPLLRRLRGATLLAQQPFPLWRAQVGDADIWLAQSGMGPKRAESVAERFAEVASPDVMVSFGFGG
GVLPGLSVGDLVMGTWCLHYDGRDFTLVAGIDAPLACSVMKALAQRTSLAVTAGTVITSGAILAKHLVAPLIPAAVTSPV
LDMETAAVASISAQRGIPLLALRAITDDAAEEFGFSLDEFTDAELNIKPYRVVTTLLRKPWIMPQLIRLARSSKRAGELL
ASAVIELVEVLPATTRCTPSYSFAQRPETADQG

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=213, Percent_Identity=25.3521126760563, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 29106; Mature: 28975

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPTTIGLIAAMPDETRPLLRRLRGATLLAQQPFPLWRAQVGDADIWLAQSGMGPKRAES
CCCCCEEEEEECCCCHHHHHHHHHCCEEEECCCCCHHHHHCCCCEEEEECCCCCHHHHHH
VAERFAEVASPDVMVSFGFGGGVLPGLSVGDLVMGTWCLHYDGRDFTLVAGIDAPLACSV
HHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHEEEEECCCCEEEEECCCCHHHHHH
MKALAQRTSLAVTAGTVITSGAILAKHLVAPLIPAAVTSPVLDMETAAVASISAQRGIPL
HHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCE
LALRAITDDAAEEFGFSLDEFTDAELNIKPYRVVTTLLRKPWIMPQLIRLARSSKRAGEL
EEHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHH
LASAVIELVEVLPATTRCTPSYSFAQRPETADQG
HHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCC
>Mature Secondary Structure 
PPTTIGLIAAMPDETRPLLRRLRGATLLAQQPFPLWRAQVGDADIWLAQSGMGPKRAES
CCCCEEEEEECCCCHHHHHHHHHCCEEEECCCCCHHHHHCCCCEEEEECCCCCHHHHHH
VAERFAEVASPDVMVSFGFGGGVLPGLSVGDLVMGTWCLHYDGRDFTLVAGIDAPLACSV
HHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHEEEEECCCCEEEEECCCCHHHHHH
MKALAQRTSLAVTAGTVITSGAILAKHLVAPLIPAAVTSPVLDMETAAVASISAQRGIPL
HHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCE
LALRAITDDAAEEFGFSLDEFTDAELNIKPYRVVTTLLRKPWIMPQLIRLARSSKRAGEL
EEHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHH
LASAVIELVEVLPATTRCTPSYSFAQRPETADQG
HHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA