Click here to switch to the map view.

The map label for this gene is efp-2

Identifier: 39996851

GI number: 39996851

Start: 1915425

End: 1915988

Strand: Direct

Name: efp-2

Synonym: GSU1752

Alternate gene names: 39996851

Gene position: 1915425-1915988 (Clockwise)

Preceding gene: 39996849

Following gene: 39996852

Centisome position: 50.22

GC content: 56.74

Gene sequence:

>564_bases
ATGTACACTGTCGCCGATCTGAAAAAGGGGCTCAAGCTTACCCTCGACGGAGCCCCCTACCTGGTCATTGCGTTCGAGTT
CTCCAAGCCGGGCAAGGGCCAGGCCCTCTATCGCACCAAGATGCGGAACATGATTACCGGCGTCATTCTCGACCGCACCT
ATCGCTCCGGGGAAACCTTCGAGCCGGCACGCCTCGAAGAGCGCCGGATGCAGTACCTGTACAAGGAAGACACCCACTAC
ACCTTCATGGACAACCAGACTTTCGAGCAGGTTCAGATGGACGAAGATGCCGTTGGCGATGCAAAAAACTTCCTCATCGA
CAATCTTGAAGTGGATATCCTCCTCTTCGGCGAGAAAGCCATCGGCGTAACGCTTCCCAACTTCGTCAATCTCCGCGTTG
TCCAGACCGATCCGTGGGTCAAGGGCGACACCTCGGGCAGCGATTCCAAGCCCGCCACCGTTGAGACGGGCTACATCCTC
CGCGTTCCCCCGTTCATCGAGGAGGGCGAGATGATTGTCATCGATACCCGTTCCGGTGAATATTCAACACGGGTCAAAGG
ATAG

Upstream 100 bases:

>100_bases
AGGTGCCGGGAACTGTATTTTTTTCTTAACAACCGTTGGATTTTAGGATAAAAAGTACCATTTTGGACTACATACCCACC
ACGAAAAGAGGATAGTATCT

Downstream 100 bases:

>100_bases
ACTCCATGACCGGTAACTGGAACCTGGCCCGCAGGCGCTCCGCGCTCTGGGCCAGGGCCCGCATCCTTGCAGAAATCAGA
CGTTTTTTTGTTGAAGGGGG

Product: elongation factor P

Products: NA

Alternate protein names: EF-P 2

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MYTVADLKKGLKLTLDGAPYLVIAFEFSKPGKGQALYRTKMRNMITGVILDRTYRSGETFEPARLEERRMQYLYKEDTHY
TFMDNQTFEQVQMDEDAVGDAKNFLIDNLEVDILLFGEKAIGVTLPNFVNLRVVQTDPWVKGDTSGSDSKPATVETGYIL
RVPPFIEEGEMIVIDTRSGEYSTRVKG

Sequences:

>Translated_187_residues
MYTVADLKKGLKLTLDGAPYLVIAFEFSKPGKGQALYRTKMRNMITGVILDRTYRSGETFEPARLEERRMQYLYKEDTHY
TFMDNQTFEQVQMDEDAVGDAKNFLIDNLEVDILLFGEKAIGVTLPNFVNLRVVQTDPWVKGDTSGSDSKPATVETGYIL
RVPPFIEEGEMIVIDTRSGEYSTRVKG
>Mature_187_residues
MYTVADLKKGLKLTLDGAPYLVIAFEFSKPGKGQALYRTKMRNMITGVILDRTYRSGETFEPARLEERRMQYLYKEDTHY
TFMDNQTFEQVQMDEDAVGDAKNFLIDNLEVDILLFGEKAIGVTLPNFVNLRVVQTDPWVKGDTSGSDSKPATVETGYIL
RVPPFIEEGEMIVIDTRSGEYSTRVKG

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=185, Percent_Identity=47.027027027027, Blast_Score=184, Evalue=4e-48,
Organism=Escherichia coli, GI87082061, Length=184, Percent_Identity=25.5434782608696, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP2_GEOSL (Q74CC2)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_952802.1
- ProteinModelPortal:   Q74CC2
- SMR:   Q74CC2
- GeneID:   2685359
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU1752
- NMPDR:   fig|243231.1.peg.1740
- TIGR:   GSU1752
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- BioCyc:   GSUL243231:GSU_1752-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21239; Mature: 21239

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTVADLKKGLKLTLDGAPYLVIAFEFSKPGKGQALYRTKMRNMITGVILDRTYRSGETF
CCCHHHHCCCCEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHEEECEECCCCCC
EPARLEERRMQYLYKEDTHYTFMDNQTFEQVQMDEDAVGDAKNFLIDNLEVDILLFGEKA
CCHHHHHHHHHHHHHCCCEEEEECCCCHHHEECCCCCCCCCHHEEECCCEEEEEEECCCE
IGVTLPNFVNLRVVQTDPWVKGDTSGSDSKPATVETGYILRVPPFIEEGEMIVIDTRSGE
EEEECCCEEEEEEEECCCCCCCCCCCCCCCCCEEECCEEEECCCCCCCCCEEEEECCCCC
YSTRVKG
EEEECCC
>Mature Secondary Structure
MYTVADLKKGLKLTLDGAPYLVIAFEFSKPGKGQALYRTKMRNMITGVILDRTYRSGETF
CCCHHHHCCCCEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHEEECEECCCCCC
EPARLEERRMQYLYKEDTHYTFMDNQTFEQVQMDEDAVGDAKNFLIDNLEVDILLFGEKA
CCHHHHHHHHHHHHHCCCEEEEECCCCHHHEECCCCCCCCCHHEEECCCEEEEEEECCCE
IGVTLPNFVNLRVVQTDPWVKGDTSGSDSKPATVETGYILRVPPFIEEGEMIVIDTRSGE
EEEECCCEEEEEEEECCCCCCCCCCCCCCCCCEEECCEEEECCCCCCCCCEEEEECCCCC
YSTRVKG
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA