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The map label for this gene is kefB [C]

Identifier: 39995634

GI number: 39995634

Start: 561008

End: 562702

Strand: Reverse

Name: kefB [C]

Synonym: GSU0527

Alternate gene names: 39995634

Gene position: 562702-561008 (Counterclockwise)

Preceding gene: 39995635

Following gene: 39995633

Centisome position: 14.75

GC content: 64.42

Gene sequence:

>1695_bases
ATGAAGGTACTCGCCTCCGAACTGGCCTATTTCCTGAGGGGCCGCGCCAGACAGAACCTGAAGGTCCTGCTCCTGTATTG
CGCCTTCCTTCTTGTCATGCTCCTGGCCTACGCGTCCATCTTCCGCTACCTGATGTGGCATCTCGAAGGACGCGAATACT
CGTTCATGGCGGGGATCTACTGGACTATCACGGTGATGACCACCCTCGGGTTCGGCGACATCACCTTCCAGAGCGACGCC
GGGTACCTGTTCGCCTCTATTGTCACCGTTTCGGGGGTGATCTTTCTCCTGATCATCCTCCCCTTCGGCTTTGTCAGCAT
GTTCCTGGCTCCCTGGATTGAACGGCGCCTCCGCTACCACCCCACCATCGAGCTGCCGGACGACACCCGGGGGCACATCC
TCATCTTCGGCATCGACCCCATCACCCGGACCCTGATCCGCAAACTGGAGAGCCGCAACCACCTGTTCGTCGTGGTAACG
GACAACTACGACCAGGCCCTGCACCTGGAAGAGCAGGAGGGGTTCAAGGTGGTCTACGGTTCGCCCACCGATGCCCACGT
CCTGGCCGGCCTGCGGGTGGCGGCGGCCCGAAGCATCATTGCCAACCTGAGCGACCCTGACAACGCCAACCTGTGCCTCA
CCGTCCGCTCCCTCTGCCAGACCCCCATCATTGCCGTGGTCAAGGAACCGGTGCACGGAGAACTGCTCCGGCTGGCCGGA
GCGAACCAGGTCGTCCCCCTGACCAGAATCCTCGGCCGCTACCTGGGCATCCGGGCCACCACCTGCGGGGCGCTGGCCCA
TATTCTCGACTCCTTCGGCAACCTGCAGATCGCCGAACTGCCCGTCCACGGCACCCCTTTCGCCGGCAAAACCATCGGGG
AATCGGGGATTCGCCAGCGGACGGGGCTTTCAATCATCGGTGTCTGGGAACGGGGCAGCCTCACCACCCCGCAACGGGAG
ACGGTCCTGACCGAGCAGTCGCTGCTGGTGCTGGCCGGCACCAAGAGCCAGTTGGCCGCCCTGGAGTATCTGATCGGCGA
GGCACCGGAAGACGAGTTGATCTTCATCATCGGCCACGGCCGCATCGGCTGCGCCGCCGCAGCGTTCCTCGACCGCAAGC
CGGTCCCCTTCATCCTGATCGACCGCCAGGAGAGCCCCGTCTGCAACGATCACGTCGTGGTCTACGGCGACGCCACCGTG
GGCCAGACCCTCAGGCAGGCGGGCATCGACCGCGCCAGCGGCATCATCGTCACCACCAATGACGACAGCACCAACATCTT
CCTGACCCTGGCCTGCCGGCACCTCCACTCCCACATCCGCATCGTGGCCCGTGCCAACGGGGAGGAAAACGTCGACCAGC
TCTACGCTGCCGGCGCCGACTTCGTCGTCTCCAACGCCTCGGTGGGTGCCAACATCCTGGGCAACCTGCTGGAGCACAAG
GAATCGGCCTTCCTCTCCGAGGGGATGGCCGTCTTCCGGCGGCCGCTGCCCCCCGCCATGGCCGGCAAAACCATTGCCGA
GACCCGCCTGCGCCCCCTCACCGGCTGCTCCATCGTGGCGATCGAGGCGCCCGACCGGGCCGACATCCTCATTTCGCCGC
CACCGGAAACCATCCTCGCAGAAGGGGCCAGACTCATCCTGATCGGCACGTCGGAACAGGAGAAAACCTTTGATCAGACC
ATTGCCGCCCGCTAA

Upstream 100 bases:

>100_bases
TACGCTCCTGCTGGGCTACCCGGCCGTCACCTATCGCCGACCTCCCCGGCGCAACCGGCTGGACGTGGTCTGGCGGTGAC
AACGTGAGGGAAGGTGCTCC

Downstream 100 bases:

>100_bases
CGGGACAGGGGGGATGAAAACAGGCAGTGATCAGCTGTAGAACTGGTGTTCGCTCGCACGAATGCGACTCGGCTGCATGA
CAGAAGGCAACCGGCTGCGG

Product: TrkA domain-containing protein

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: MjK1 [H]

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MKVLASELAYFLRGRARQNLKVLLLYCAFLLVMLLAYASIFRYLMWHLEGREYSFMAGIYWTITVMTTLGFGDITFQSDA
GYLFASIVTVSGVIFLLIILPFGFVSMFLAPWIERRLRYHPTIELPDDTRGHILIFGIDPITRTLIRKLESRNHLFVVVT
DNYDQALHLEEQEGFKVVYGSPTDAHVLAGLRVAAARSIIANLSDPDNANLCLTVRSLCQTPIIAVVKEPVHGELLRLAG
ANQVVPLTRILGRYLGIRATTCGALAHILDSFGNLQIAELPVHGTPFAGKTIGESGIRQRTGLSIIGVWERGSLTTPQRE
TVLTEQSLLVLAGTKSQLAALEYLIGEAPEDELIFIIGHGRIGCAAAAFLDRKPVPFILIDRQESPVCNDHVVVYGDATV
GQTLRQAGIDRASGIIVTTNDDSTNIFLTLACRHLHSHIRIVARANGEENVDQLYAAGADFVVSNASVGANILGNLLEHK
ESAFLSEGMAVFRRPLPPAMAGKTIAETRLRPLTGCSIVAIEAPDRADILISPPPETILAEGARLILIGTSEQEKTFDQT
IAAR

Sequences:

>Translated_564_residues
MKVLASELAYFLRGRARQNLKVLLLYCAFLLVMLLAYASIFRYLMWHLEGREYSFMAGIYWTITVMTTLGFGDITFQSDA
GYLFASIVTVSGVIFLLIILPFGFVSMFLAPWIERRLRYHPTIELPDDTRGHILIFGIDPITRTLIRKLESRNHLFVVVT
DNYDQALHLEEQEGFKVVYGSPTDAHVLAGLRVAAARSIIANLSDPDNANLCLTVRSLCQTPIIAVVKEPVHGELLRLAG
ANQVVPLTRILGRYLGIRATTCGALAHILDSFGNLQIAELPVHGTPFAGKTIGESGIRQRTGLSIIGVWERGSLTTPQRE
TVLTEQSLLVLAGTKSQLAALEYLIGEAPEDELIFIIGHGRIGCAAAAFLDRKPVPFILIDRQESPVCNDHVVVYGDATV
GQTLRQAGIDRASGIIVTTNDDSTNIFLTLACRHLHSHIRIVARANGEENVDQLYAAGADFVVSNASVGANILGNLLEHK
ESAFLSEGMAVFRRPLPPAMAGKTIAETRLRPLTGCSIVAIEAPDRADILISPPPETILAEGARLILIGTSEQEKTFDQT
IAAR
>Mature_564_residues
MKVLASELAYFLRGRARQNLKVLLLYCAFLLVMLLAYASIFRYLMWHLEGREYSFMAGIYWTITVMTTLGFGDITFQSDA
GYLFASIVTVSGVIFLLIILPFGFVSMFLAPWIERRLRYHPTIELPDDTRGHILIFGIDPITRTLIRKLESRNHLFVVVT
DNYDQALHLEEQEGFKVVYGSPTDAHVLAGLRVAAARSIIANLSDPDNANLCLTVRSLCQTPIIAVVKEPVHGELLRLAG
ANQVVPLTRILGRYLGIRATTCGALAHILDSFGNLQIAELPVHGTPFAGKTIGESGIRQRTGLSIIGVWERGSLTTPQRE
TVLTEQSLLVLAGTKSQLAALEYLIGEAPEDELIFIIGHGRIGCAAAAFLDRKPVPFILIDRQESPVCNDHVVVYGDATV
GQTLRQAGIDRASGIIVTTNDDSTNIFLTLACRHLHSHIRIVARANGEENVDQLYAAGADFVVSNASVGANILGNLLEHK
ESAFLSEGMAVFRRPLPPAMAGKTIAETRLRPLTGCSIVAIEAPDRADILISPPPETILAEGARLILIGTSEQEKTFDQT
IAAR

Specific function: Potassium channel protein. Seems to conduct potassium at low membrane potentials [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR003280
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF07885 Ion_trans_2; PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 61670; Mature: 61670

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLASELAYFLRGRARQNLKVLLLYCAFLLVMLLAYASIFRYLMWHLEGREYSFMAGIY
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHH
WTITVMTTLGFGDITFQSDAGYLFASIVTVSGVIFLLIILPFGFVSMFLAPWIERRLRYH
HHEEHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTIELPDDTRGHILIFGIDPITRTLIRKLESRNHLFVVVTDNYDQALHLEEQEGFKVVYG
CCEECCCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCEEEEEC
SPTDAHVLAGLRVAAARSIIANLSDPDNANLCLTVRSLCQTPIIAVVKEPVHGELLRLAG
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHCCCEEEECCCCCCCHHHHHCC
ANQVVPLTRILGRYLGIRATTCGALAHILDSFGNLQIAELPVHGTPFAGKTIGESGIRQR
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHCCHHH
TGLSIIGVWERGSLTTPQRETVLTEQSLLVLAGTKSQLAALEYLIGEAPEDELIFIIGHG
CCCEEEEEECCCCCCCCCHHHEECCCCEEEEECCHHHHHHHHHHHCCCCCCCEEEEEECC
RIGCAAAAFLDRKPVPFILIDRQESPVCNDHVVVYGDATVGQTLRQAGIDRASGIIVTTN
CHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEECCHHHHHHHHHCCCHHCCEEEEEC
DDSTNIFLTLACRHLHSHIRIVARANGEENVDQLYAAGADFVVSNASVGANILGNLLEHK
CCCCEEEEEHHHHHHHHHEEEEEECCCCCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHH
ESAFLSEGMAVFRRPLPPAMAGKTIAETRLRPLTGCSIVAIEAPDRADILISPPPETILA
HHHHHHHHHHHHHCCCCHHHCCCHHHHHCCCCCCCCEEEEEECCCCCCEEECCCCHHHHH
EGARLILIGTSEQEKTFDQTIAAR
CCCEEEEEECCCHHHHHHHHHCCC
>Mature Secondary Structure
MKVLASELAYFLRGRARQNLKVLLLYCAFLLVMLLAYASIFRYLMWHLEGREYSFMAGIY
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHH
WTITVMTTLGFGDITFQSDAGYLFASIVTVSGVIFLLIILPFGFVSMFLAPWIERRLRYH
HHEEHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTIELPDDTRGHILIFGIDPITRTLIRKLESRNHLFVVVTDNYDQALHLEEQEGFKVVYG
CCEECCCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCEEEEEC
SPTDAHVLAGLRVAAARSIIANLSDPDNANLCLTVRSLCQTPIIAVVKEPVHGELLRLAG
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHCCCEEEECCCCCCCHHHHHCC
ANQVVPLTRILGRYLGIRATTCGALAHILDSFGNLQIAELPVHGTPFAGKTIGESGIRQR
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHCCHHH
TGLSIIGVWERGSLTTPQRETVLTEQSLLVLAGTKSQLAALEYLIGEAPEDELIFIIGHG
CCCEEEEEECCCCCCCCCHHHEECCCCEEEEECCHHHHHHHHHHHCCCCCCCEEEEEECC
RIGCAAAAFLDRKPVPFILIDRQESPVCNDHVVVYGDATVGQTLRQAGIDRASGIIVTTN
CHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEECCHHHHHHHHHCCCHHCCEEEEEC
DDSTNIFLTLACRHLHSHIRIVARANGEENVDQLYAAGADFVVSNASVGANILGNLLEHK
CCCCEEEEEHHHHHHHHHEEEEEECCCCCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHH
ESAFLSEGMAVFRRPLPPAMAGKTIAETRLRPLTGCSIVAIEAPDRADILISPPPETILA
HHHHHHHHHHHHHCCCCHHHCCCHHHHHCCCCCCCCEEEEEECCCCCCEEECCCCHHHHH
EGARLILIGTSEQEKTFDQTIAAR
CCCEEEEEECCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]