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The map label for this gene is dtd

Identifier: 39995632

GI number: 39995632

Start: 559887

End: 560345

Strand: Reverse

Name: dtd

Synonym: GSU0525

Alternate gene names: 39995632

Gene position: 560345-559887 (Counterclockwise)

Preceding gene: 39995633

Following gene: 39995631

Centisome position: 14.69

GC content: 62.31

Gene sequence:

>459_bases
ATGAAGGCGGTGATCCAGCGGGTAAGCGAGGCCCGGGTGGAGGTGGACGGGTCAACGGTGGGAGCCATCGGCCGGGGGAT
TCTGGTTCTTCTCGGAGTGGAGAAGGGGGATACAGAGCGGGACGCGGCCTGGCTGGCGGAGAAAATGGCGGGGCTGCGCA
TCTTCGAGGATGACGCAGGCAAGATGAATCTGTCGGTGCGGGAGGTTGAGGGATCGATCCTTGCCGTATCCCAGTTCACC
CTGGCGGGAAACTGTGCCAAGGGAAGGCGCCCCTCCTTCGACACGGCGGCCCCACCGGATGAGGGGAAGCGGCTCTACGA
CCGGTTCGTCGATTTAATCCGGGAAACCGGCATCCCCACCGCCACCGGCATTTTCCAGGCAGATATGAAGGTGCATCTGG
TGAATGACGGTCCGGTGACCTTCATCCTGGACACCAAAAGCCGGAGTTCCTCCACGTGA

Upstream 100 bases:

>100_bases
CCCTGGAGCGCTACCCGGAACTGGAGCGGGTGATCTTCACCCCCTTCGGCGCGGAGGCGGAGGCGGCCTACCGGGCGGCT
CTCGCGCGGGTGTTCGGCCC

Downstream 100 bases:

>100_bases
TACCGGGAACGCAAATCGGACGGAGCGCGGCGCAGCTCTCCCGGCAGGGGGCCATCGTCCCTTTTTTTCTTCATGAAGAC
GATCACCCTGTGGTATACCA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MKAVIQRVSEARVEVDGSTVGAIGRGILVLLGVEKGDTERDAAWLAEKMAGLRIFEDDAGKMNLSVREVEGSILAVSQFT
LAGNCAKGRRPSFDTAAPPDEGKRLYDRFVDLIRETGIPTATGIFQADMKVHLVNDGPVTFILDTKSRSSST

Sequences:

>Translated_152_residues
MKAVIQRVSEARVEVDGSTVGAIGRGILVLLGVEKGDTERDAAWLAEKMAGLRIFEDDAGKMNLSVREVEGSILAVSQFT
LAGNCAKGRRPSFDTAAPPDEGKRLYDRFVDLIRETGIPTATGIFQADMKVHLVNDGPVTFILDTKSRSSST
>Mature_152_residues
MKAVIQRVSEARVEVDGSTVGAIGRGILVLLGVEKGDTERDAAWLAEKMAGLRIFEDDAGKMNLSVREVEGSILAVSQFT
LAGNCAKGRRPSFDTAAPPDEGKRLYDRFVDLIRETGIPTATGIFQADMKVHLVNDGPVTFILDTKSRSSST

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=156, Percent_Identity=42.9487179487179, Blast_Score=120, Evalue=5e-28,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=55.9440559440559, Blast_Score=155, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI115533292, Length=151, Percent_Identity=40.3973509933775, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=38.5135135135135, Blast_Score=102, Evalue=3e-23,
Organism=Drosophila melanogaster, GI281361569, Length=153, Percent_Identity=38.562091503268, Blast_Score=108, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_GEOSL (Q74FT1)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_951583.1
- ProteinModelPortal:   Q74FT1
- SMR:   Q74FT1
- GeneID:   2685805
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU0525
- NMPDR:   fig|243231.1.peg.521
- TIGR:   GSU0525
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- BioCyc:   GSUL243231:GSU_0525-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16368; Mature: 16368

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVIQRVSEARVEVDGSTVGAIGRGILVLLGVEKGDTERDAAWLAEKMAGLRIFEDDAG
CHHHHHHHHHHEEEECCCEECHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEECCCC
KMNLSVREVEGSILAVSQFTLAGNCAKGRRPSFDTAAPPDEGKRLYDRFVDLIRETGIPT
EEEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
ATGIFQADMKVHLVNDGPVTFILDTKSRSSST
CCCEEEECEEEEEECCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MKAVIQRVSEARVEVDGSTVGAIGRGILVLLGVEKGDTERDAAWLAEKMAGLRIFEDDAG
CHHHHHHHHHHEEEECCCEECHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEECCCC
KMNLSVREVEGSILAVSQFTLAGNCAKGRRPSFDTAAPPDEGKRLYDRFVDLIRETGIPT
EEEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
ATGIFQADMKVHLVNDGPVTFILDTKSRSSST
CCCEEEECEEEEEECCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA