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The map label for this gene is cobT [H]

Identifier: 38234209

GI number: 38234209

Start: 1667803

End: 1668873

Strand: Direct

Name: cobT [H]

Synonym: DIP1634

Alternate gene names: 38234209

Gene position: 1667803-1668873 (Clockwise)

Preceding gene: 38234208

Following gene: 38234210

Centisome position: 67.02

GC content: 51.17

Gene sequence:

>1071_bases
ATGCAGCCTTCGGACTTTTTTCCAAAGATTGACTACCCAGATGAAGACCTAGCTCAGCAAGCTCGCGAGCTACAACTTAA
TCTGACGAAACCTACGGGGTCATTATCGCGGCTTGAGGATCTTGGTGTGTGGTTGTCGTCATGCCAAGGTCAGGTTCCGC
CGCATCAAATTTCCCGCCCTCGCATGGTCATTTTTGCAGGTGACCATGGCATCGCATTAAATAGCGTATCGCCCTACCCC
ATCGAAGTATCGCTACAGATGGCCGAAAATATTCGCAATGGTGGTGCTGGTATCAACGCAATTTCGAATGCTTCCGGAAT
CGGTGTACGAGTTGCCGATATTTCGCTGAACCACGATGTGGACGGCCCAGAGCGCGTTTCTCGGTCATGCGGTTCTATCG
ATCATGAAGATGCGATGACCGAAGAACAATTGGTGCGTGCCATTGAGATCGGTAAGCGTATCGCCGACGAGGAAATCGAC
GCTGGAGCCGATCTTCTTATGGCTGGAGATTTGGGCATTGGTAACACCACACCTTCTGCTGTCATCATTGGCCTTTTTTC
ACACCAGGAACCTGTCGTGGTTACTGGTCGCGGTTCTGGAGTAGACGATGAAGGATGGAAGCGTAAAGTCGCAGCCGTTC
GCGATGCGATGTTCCGTGTGCGCAAATATCGCGATGATCCACTAGCAATTATGCAGAAAGTAACTTCCCCTGAGTTGGTT
GCTATGGGAGCTTTTATCGCTCAAGCTGCAGTGCGTCGCACCCCAGTTATTTTGGATGGAGTTGTAGTTACCGCATCGGC
AATTTTGGCTGAGAACTTAGCGCCTGGTGCGCGTAAGTGGATGCAAGCCGGACATCAATCAGCCGAGCCTGCTCATAAGT
TCGCTTTAAGCTACCTAGGTCTAGAACCTCTGCTTAAATTGGGACTTCGTTTGGGCGAAGGATCGGGCGCGGCTTCAGCA
TTCCCTCTGGTTCAGATTGCTGCTCATATCATGACGGACATGGCCACTTTTGATACTGCGGGTGTTTCTGGCAAAGGTGC
AGTCCCTGCCAATCGCTCGATGAAACAGTAG

Upstream 100 bases:

>100_bases
CTCGTTGTTGCGGGATTGGCACTAGAGTTGAAACCCGTAAGTGGCGACTAGTGCCAACAGCCTTTGTTACCTATTGCTCC
ATGCTTCAAGGAGATACCTG

Downstream 100 bases:

>100_bases
TTTCTATATGTCTGGCAAAGCATATTTTGTCAACGGTGAGCATGGGCCTGCGATTATCGAAGGCCCACTGACTGCACTGA
ATTGGTTAACTATTTTACCT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MQPSDFFPKIDYPDEDLAQQARELQLNLTKPTGSLSRLEDLGVWLSSCQGQVPPHQISRPRMVIFAGDHGIALNSVSPYP
IEVSLQMAENIRNGGAGINAISNASGIGVRVADISLNHDVDGPERVSRSCGSIDHEDAMTEEQLVRAIEIGKRIADEEID
AGADLLMAGDLGIGNTTPSAVIIGLFSHQEPVVVTGRGSGVDDEGWKRKVAAVRDAMFRVRKYRDDPLAIMQKVTSPELV
AMGAFIAQAAVRRTPVILDGVVVTASAILAENLAPGARKWMQAGHQSAEPAHKFALSYLGLEPLLKLGLRLGEGSGAASA
FPLVQIAAHIMTDMATFDTAGVSGKGAVPANRSMKQ

Sequences:

>Translated_356_residues
MQPSDFFPKIDYPDEDLAQQARELQLNLTKPTGSLSRLEDLGVWLSSCQGQVPPHQISRPRMVIFAGDHGIALNSVSPYP
IEVSLQMAENIRNGGAGINAISNASGIGVRVADISLNHDVDGPERVSRSCGSIDHEDAMTEEQLVRAIEIGKRIADEEID
AGADLLMAGDLGIGNTTPSAVIIGLFSHQEPVVVTGRGSGVDDEGWKRKVAAVRDAMFRVRKYRDDPLAIMQKVTSPELV
AMGAFIAQAAVRRTPVILDGVVVTASAILAENLAPGARKWMQAGHQSAEPAHKFALSYLGLEPLLKLGLRLGEGSGAASA
FPLVQIAAHIMTDMATFDTAGVSGKGAVPANRSMKQ
>Mature_356_residues
MQPSDFFPKIDYPDEDLAQQARELQLNLTKPTGSLSRLEDLGVWLSSCQGQVPPHQISRPRMVIFAGDHGIALNSVSPYP
IEVSLQMAENIRNGGAGINAISNASGIGVRVADISLNHDVDGPERVSRSCGSIDHEDAMTEEQLVRAIEIGKRIADEEID
AGADLLMAGDLGIGNTTPSAVIIGLFSHQEPVVVTGRGSGVDDEGWKRKVAAVRDAMFRVRKYRDDPLAIMQKVTSPELV
AMGAFIAQAAVRRTPVILDGVVVTASAILAENLAPGARKWMQAGHQSAEPAHKFALSYLGLEPLLKLGLRLGEGSGAASA
FPLVQIAAHIMTDMATFDTAGVSGKGAVPANRSMKQ

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=343, Percent_Identity=30.0291545189504, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 37844; Mature: 37844

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPSDFFPKIDYPDEDLAQQARELQLNLTKPTGSLSRLEDLGVWLSSCQGQVPPHQISRP
CCCCCCCCCCCCCCHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHCCCC
RMVIFAGDHGIALNSVSPYPIEVSLQMAENIRNGGAGINAISNASGIGVRVADISLNHDV
EEEEEECCCCEEECCCCCCCEEEEHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCC
DGPERVSRSCGSIDHEDAMTEEQLVRAIEIGKRIADEEIDAGADLLMAGDLGIGNTTPSA
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCC
VIIGLFSHQEPVVVTGRGSGVDDEGWKRKVAAVRDAMFRVRKYRDDPLAIMQKVTSPELV
EEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHH
AMGAFIAQAAVRRTPVILDGVVVTASAILAENLAPGARKWMQAGHQSAEPAHKFALSYLG
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHC
LEPLLKLGLRLGEGSGAASAFPLVQIAAHIMTDMATFDTAGVSGKGAVPANRSMKQ
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQPSDFFPKIDYPDEDLAQQARELQLNLTKPTGSLSRLEDLGVWLSSCQGQVPPHQISRP
CCCCCCCCCCCCCCHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHCCCC
RMVIFAGDHGIALNSVSPYPIEVSLQMAENIRNGGAGINAISNASGIGVRVADISLNHDV
EEEEEECCCCEEECCCCCCCEEEEHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCC
DGPERVSRSCGSIDHEDAMTEEQLVRAIEIGKRIADEEIDAGADLLMAGDLGIGNTTPSA
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCC
VIIGLFSHQEPVVVTGRGSGVDDEGWKRKVAAVRDAMFRVRKYRDDPLAIMQKVTSPELV
EEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHH
AMGAFIAQAAVRRTPVILDGVVVTASAILAENLAPGARKWMQAGHQSAEPAHKFALSYLG
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHC
LEPLLKLGLRLGEGSGAASAFPLVQIAAHIMTDMATFDTAGVSGKGAVPANRSMKQ
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]