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The map label for this gene is cobU [H]

Identifier: 38234208

GI number: 38234208

Start: 1667205

End: 1667753

Strand: Direct

Name: cobU [H]

Synonym: DIP1633

Alternate gene names: 38234208

Gene position: 1667205-1667753 (Clockwise)

Preceding gene: 38234207

Following gene: 38234209

Centisome position: 66.99

GC content: 52.09

Gene sequence:

>549_bases
ATGCTCACGCTAGTGTTGGGCGGAGCACGCTCGGGAAAATCAGTGTTCGCTGAACAGCTCGTGGGGGCACAATCGTGCCT
CTACGTAGCCACGGCGCGTCCGTTTGAAGGGGAATTCGACGCTGACTTTCGTTCTCGGATTGCAACACATATCGAGCGAC
GACCTAAATATTGGAACACAAATGACCAACACGACCTCATCGAAATTCTTAAAAACGAGCAGCTAGATCACGACACGCTA
TTGGTCGATGATCTCGGCACATGGCTCACTCACATTCTTGATACTCAAAAAGCATGGGACGACCCCACTCAGTTAGTTTC
TACTGTGTGTGACGACCTCGTTGCAGCGCTTTCCGCTGCTGGCAAGAACCGCAACATCATAGTGGTGAGTCCAGAAGTTG
GAATGGGCATTATTCCTTCTCACCCAGCTGGCCGACGCTTCCGCGACTCTATTGGAAAAGTAAACGCTGCTGTGGCAGCT
TGTTGCGACCGAGTGGTGCTCGTTGTTGCGGGATTGGCACTAGAGTTGAAACCCGTAAGTGGCGACTAG

Upstream 100 bases:

>100_bases
CGCTTTCTCTCTCGGATTCTATGCCTATGGTAGAGCAACACAGCCACGTCGCTGGCGTACGCCAAAGCCACAGGTCAATA
TCGGAGATAAGGTTTCCTAA

Downstream 100 bases:

>100_bases
TGCCAACAGCCTTTGTTACCTATTGCTCCATGCTTCAAGGAGATACCTGATGCAGCCTTCGGACTTTTTTCCAAAGATTG
ACTACCCAGATGAAGACCTA

Product: putative cobinamide kinase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MLTLVLGGARSGKSVFAEQLVGAQSCLYVATARPFEGEFDADFRSRIATHIERRPKYWNTNDQHDLIEILKNEQLDHDTL
LVDDLGTWLTHILDTQKAWDDPTQLVSTVCDDLVAALSAAGKNRNIIVVSPEVGMGIIPSHPAGRRFRDSIGKVNAAVAA
CCDRVVLVVAGLALELKPVSGD

Sequences:

>Translated_182_residues
MLTLVLGGARSGKSVFAEQLVGAQSCLYVATARPFEGEFDADFRSRIATHIERRPKYWNTNDQHDLIEILKNEQLDHDTL
LVDDLGTWLTHILDTQKAWDDPTQLVSTVCDDLVAALSAAGKNRNIIVVSPEVGMGIIPSHPAGRRFRDSIGKVNAAVAA
CCDRVVLVVAGLALELKPVSGD
>Mature_182_residues
MLTLVLGGARSGKSVFAEQLVGAQSCLYVATARPFEGEFDADFRSRIATHIERRPKYWNTNDQHDLIEILKNEQLDHDTL
LVDDLGTWLTHILDTQKAWDDPTQLVSTVCDDLVAALSAAGKNRNIIVVSPEVGMGIIPSHPAGRRFRDSIGKVNAAVAA
CCDRVVLVVAGLALELKPVSGD

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=186, Percent_Identity=35.4838709677419, Blast_Score=93, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 19776; Mature: 19776

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLVLGGARSGKSVFAEQLVGAQSCLYVATARPFEGEFDADFRSRIATHIERRPKYWNT
CEEEEECCCCCCHHHHHHHHHCHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCC
NDQHDLIEILKNEQLDHDTLLVDDLGTWLTHILDTQKAWDDPTQLVSTVCDDLVAALSAA
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
GKNRNIIVVSPEVGMGIIPSHPAGRRFRDSIGKVNAAVAACCDRVVLVVAGLALELKPVS
CCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECC
GD
CC
>Mature Secondary Structure
MLTLVLGGARSGKSVFAEQLVGAQSCLYVATARPFEGEFDADFRSRIATHIERRPKYWNT
CEEEEECCCCCCHHHHHHHHHCHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCC
NDQHDLIEILKNEQLDHDTLLVDDLGTWLTHILDTQKAWDDPTQLVSTVCDDLVAALSAA
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
GKNRNIIVVSPEVGMGIIPSHPAGRRFRDSIGKVNAAVAACCDRVVLVVAGLALELKPVS
CCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECC
GD
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 9601028; 10529169 [H]