Click here to switch to the map view.

The map label for this gene is xerC [H]

Identifier: 38234089

GI number: 38234089

Start: 1533714

End: 1534622

Strand: Reverse

Name: xerC [H]

Synonym: DIP1510

Alternate gene names: 38234089

Gene position: 1534622-1533714 (Counterclockwise)

Preceding gene: 38234090

Following gene: 38234087

Centisome position: 61.67

GC content: 48.4

Gene sequence:

>909_bases
GTGCCAGCCCAACTAACCGAACTTGTCGACGATTTCTGTGAGTATCTGGATTTGGGCTTGGGGCGATCGCCGGCCACTGT
CCGTTCTTATAAAAGTGACCTCTTTGGTTTTGTAAATCGATTTGCCACATTAGATCAATTTACGTTGGACAATGTGCGAG
AGTGGTTGGCTCAAGCGGTCGCCGACGGTAAATCTCGTGCAACTATCGCACGTCGTACTGCGTCGATAAAAGCGTTTAGT
GGATGGTTGCTGCGAAACGGCTACAACGATATAGATGTGGCTGCACGGTTGGTAGCGCCGAAGGTGCAACGCACATTGCC
TATGGTAGTAAGCGAGCGCACCATGACGAATATCGTCGAAAAGCCGGCTTCGACGACTGAAGATACTTTTGTTCGTGATC
GTGCTATTTGTGAGTTGTTGTATGCGTCGGGAATTCGTGTATCTGAGCTTTGTGGATTGAATACTGGTGATGTTGATCTC
AAACGTCAAACTGCTCGAGTAACGGGTAAAGGAAATAAACAACGTGTTGTTCCATTCGGAGACCAAGCTACAGCGGCACT
TTCCCATTGGCTAAATGGGGTGCGAAGCGAAATGTTGATTTCTGCCGGATGTACAAGCGGAGTAGATGCGTTATTTGTAG
GGGTGCGGGGTAAAAGGATCGATCCACGCCAAGTAAGGCGAATTGTGGAAACCTCTGGTCAAGAACACGGAATAGGTGGC
TTAGCTCCGCACGCACTGCGGCATACAGCAGCAACGCACCTACTCGATAATGGAGCAGATCTCAGGGTTGTGCAAGAAAT
GCTGGGACACTCCTCTTTGAATACCACTCAGATATATACACATGTAAGTACTCAACGGCTTAAGGAAGCGTATAAAAACG
CACATCCCCGTGCGCAAAAAAACTTGTAG

Upstream 100 bases:

>100_bases
CTTCGGAACTAGGGTTATGCACTATGGGTGAGTCAGTAGTAGAGGTGAAAAGTTGTCACAGGCTTTTCACCTCTACTGTG
TATTTAGCTGAGAGGGAAAC

Downstream 100 bases:

>100_bases
TGCTTGGCAAAGAGTTATTTTGACCGAACCCTCATCTGAGGTGGTTTTAGCCGAATGTGCAATGGTTCGAGAAGACTGAG
GGGATTGAGGTAGTTGTCCT

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MPAQLTELVDDFCEYLDLGLGRSPATVRSYKSDLFGFVNRFATLDQFTLDNVREWLAQAVADGKSRATIARRTASIKAFS
GWLLRNGYNDIDVAARLVAPKVQRTLPMVVSERTMTNIVEKPASTTEDTFVRDRAICELLYASGIRVSELCGLNTGDVDL
KRQTARVTGKGNKQRVVPFGDQATAALSHWLNGVRSEMLISAGCTSGVDALFVGVRGKRIDPRQVRRIVETSGQEHGIGG
LAPHALRHTAATHLLDNGADLRVVQEMLGHSSLNTTQIYTHVSTQRLKEAYKNAHPRAQKNL

Sequences:

>Translated_302_residues
MPAQLTELVDDFCEYLDLGLGRSPATVRSYKSDLFGFVNRFATLDQFTLDNVREWLAQAVADGKSRATIARRTASIKAFS
GWLLRNGYNDIDVAARLVAPKVQRTLPMVVSERTMTNIVEKPASTTEDTFVRDRAICELLYASGIRVSELCGLNTGDVDL
KRQTARVTGKGNKQRVVPFGDQATAALSHWLNGVRSEMLISAGCTSGVDALFVGVRGKRIDPRQVRRIVETSGQEHGIGG
LAPHALRHTAATHLLDNGADLRVVQEMLGHSSLNTTQIYTHVSTQRLKEAYKNAHPRAQKNL
>Mature_301_residues
PAQLTELVDDFCEYLDLGLGRSPATVRSYKSDLFGFVNRFATLDQFTLDNVREWLAQAVADGKSRATIARRTASIKAFSG
WLLRNGYNDIDVAARLVAPKVQRTLPMVVSERTMTNIVEKPASTTEDTFVRDRAICELLYASGIRVSELCGLNTGDVDLK
RQTARVTGKGNKQRVVPFGDQATAALSHWLNGVRSEMLISAGCTSGVDALFVGVRGKRIDPRQVRRIVETSGQEHGIGGL
APHALRHTAATHLLDNGADLRVVQEMLGHSSLNTTQIYTHVSTQRLKEAYKNAHPRAQKNL

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=296, Percent_Identity=36.4864864864865, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1790244, Length=298, Percent_Identity=34.8993288590604, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI1790768, Length=161, Percent_Identity=30.4347826086957, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790767, Length=160, Percent_Identity=28.125, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33229; Mature: 33098

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAQLTELVDDFCEYLDLGLGRSPATVRSYKSDLFGFVNRFATLDQFTLDNVREWLAQAV
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADGKSRATIARRTASIKAFSGWLLRNGYNDIDVAARLVAPKVQRTLPMVVSERTMTNIVE
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KPASTTEDTFVRDRAICELLYASGIRVSELCGLNTGDVDLKRQTARVTGKGNKQRVVPFG
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEECC
DQATAALSHWLNGVRSEMLISAGCTSGVDALFVGVRGKRIDPRQVRRIVETSGQEHGIGG
CHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEECCCCCCCHHHHHHHHHHCCCCCCCCC
LAPHALRHTAATHLLDNGADLRVVQEMLGHSSLNTTQIYTHVSTQRLKEAYKNAHPRAQK
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHC
NL
CC
>Mature Secondary Structure 
PAQLTELVDDFCEYLDLGLGRSPATVRSYKSDLFGFVNRFATLDQFTLDNVREWLAQAV
CHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADGKSRATIARRTASIKAFSGWLLRNGYNDIDVAARLVAPKVQRTLPMVVSERTMTNIVE
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KPASTTEDTFVRDRAICELLYASGIRVSELCGLNTGDVDLKRQTARVTGKGNKQRVVPFG
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEECC
DQATAALSHWLNGVRSEMLISAGCTSGVDALFVGVRGKRIDPRQVRRIVETSGQEHGIGG
CHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEECCCCCCCHHHHHHHHHHCCCCCCCCC
LAPHALRHTAATHLLDNGADLRVVQEMLGHSSLNTTQIYTHVSTQRLKEAYKNAHPRAQK
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHC
NL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]