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The map label for this gene is mqo

Identifier: 38234071

GI number: 38234071

Start: 1513204

End: 1514703

Strand: Reverse

Name: mqo

Synonym: DIP1492

Alternate gene names: 38234071

Gene position: 1514703-1513204 (Counterclockwise)

Preceding gene: 38234074

Following gene: 38234070

Centisome position: 60.86

GC content: 51.73

Gene sequence:

>1500_bases
ATGGCAGACTCCACCACTGCGCAACATGTCACCGACGAGGTCGATGTTGCGCTCATCGGTGCCGGCATTATGAGCGCTAC
GTTGGGTGCAATGCTTCGCACCCTAGAACCTGGTTGGACCCAGGTTATGTTCGAGCGCTTGGATGCCCCCGCGCAAGAAT
CTTCTTCACCTTGGAATAACGCAGGTACAGGTCACTCGGCACTATGCGAGCTGAACTACACGCCTGAGGTGAAGGGGCGG
GTACAAATTGACAAGGCTTTGGGCGTTAACGAAAAGTTCCAAATTTCTCGTCAGTTTTGGTCTTACCAAGTAAATGAAGG
CGTTTTGCCTTCGCCACGTGAGTGGATCAACCCAGTTCCACACGTATCCTTCGGACGTGGCGAGGATCAAGTTGCTTATT
TGAAGAAGCGCTACGAGGCGCTTGCTGCGCACCCTTTGTTCCCGAACATGCAATATACGGATGATCGTGCCAAGTTCGCT
GAAATGCTGCCGCTTATGGCTGATGGTCGTAGCGAGTTTGAAAAAGTTGCTATTTCATGGACCGACGCTGGTACGGACAT
CAACTATGGTTCCCAGACGCGTCAATTCCTTAAAGCCGCAGAGAAAAATGGCACCGAGATCCGTTATGGGCACGAAGTTA
AAGACATCAAGCGTGATGGTGCTAAGTGGCGTGTGACGGTCAAGAATGTTCATACCGGAGATACCCAAGTTATTCGCGCT
AACTTTGTGTTTGTTGGTGCTGGCGGCATGGCATTGCCATTGCTGCAGAAAACAGGCATTGTGGAAATCCGTGGTTGGGG
CGGCTTCCCAGTTTCGGGTCAGTGGCTACGATGCACTAATCCTGACATTATTGAACAGCATGCTGCCAAGGTTTATGGCA
AGGCATCAATTGGTGCGCCTCCGATGTCGGTTCCACACCTTGACACCCGTGTGATCGACGGTGAAAAGGGCTTGCTGTTT
GGCCCTTATGCTGGTTGGACTCCGAAGTTCTTGAAGAAGGGCTCCTATTTGGATCTCTTTAAGTCGATTCGTCCGACCAA
CTTGATGTCCTACTTGGGTGTTGGTGCACAAGAGTTCGGCCTTACCAAGTACCTCATCACGGAGGTCATGAAGGATCAGG
CTGCGCGCATGGAATCGCTGCGTGAATACATGCCTAATGCAAAGGATGAGGATTGGGAGCTGGTCACTGCTGGTCAGCGT
GTGCAGGCAATTCAGCCTGTTGTTGGTCCTCGATTCTCGACTCTTGCGTTTGGTACTTCATTGATCAACTCTGCTGACGG
CTCCGTAGCGGGAATCTTGGGTGCCTCGCCTGGTGCGTCTATCGCTCCAGCTGCAATGCTTGAGCTGCTCGAGCGCTGCT
TCGGTCAGAAGATGGTGGAATGGGGTCCAACGATCAAAGACATGATCCCTTCATACGGTATCCGTTTGGCAACGGATCAG
AAGCTCTTCAACGAGATCTGGGATCACACCCAAGCAACTTTGCAGCTTGATAAGAAGTAA

Upstream 100 bases:

>100_bases
AAAATGTGTGAATTCCTACAGCGGTTGCCGAGTGATCGGCTGATTTTAGTTCATGGGACACTGGGAAATACGTCGAAGGC
AATACTCAAGGAAGTTTAAA

Downstream 100 bases:

>100_bases
AGCTGCGTTGTACACATTTTAATGGTGTATGTGGGATTAACCTAGATCTCAATGCCTCGTCGTTCGGTGCATAGAAAATG
CCCATTTCGGCGAGGTATTT

Product: malate:quinone oxidoreductase

Products: NA

Alternate protein names: MQO; Malate dehydrogenase [quinone]

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MADSTTAQHVTDEVDVALIGAGIMSATLGAMLRTLEPGWTQVMFERLDAPAQESSSPWNNAGTGHSALCELNYTPEVKGR
VQIDKALGVNEKFQISRQFWSYQVNEGVLPSPREWINPVPHVSFGRGEDQVAYLKKRYEALAAHPLFPNMQYTDDRAKFA
EMLPLMADGRSEFEKVAISWTDAGTDINYGSQTRQFLKAAEKNGTEIRYGHEVKDIKRDGAKWRVTVKNVHTGDTQVIRA
NFVFVGAGGMALPLLQKTGIVEIRGWGGFPVSGQWLRCTNPDIIEQHAAKVYGKASIGAPPMSVPHLDTRVIDGEKGLLF
GPYAGWTPKFLKKGSYLDLFKSIRPTNLMSYLGVGAQEFGLTKYLITEVMKDQAARMESLREYMPNAKDEDWELVTAGQR
VQAIQPVVGPRFSTLAFGTSLINSADGSVAGILGASPGASIAPAAMLELLERCFGQKMVEWGPTIKDMIPSYGIRLATDQ
KLFNEIWDHTQATLQLDKK

Sequences:

>Translated_499_residues
MADSTTAQHVTDEVDVALIGAGIMSATLGAMLRTLEPGWTQVMFERLDAPAQESSSPWNNAGTGHSALCELNYTPEVKGR
VQIDKALGVNEKFQISRQFWSYQVNEGVLPSPREWINPVPHVSFGRGEDQVAYLKKRYEALAAHPLFPNMQYTDDRAKFA
EMLPLMADGRSEFEKVAISWTDAGTDINYGSQTRQFLKAAEKNGTEIRYGHEVKDIKRDGAKWRVTVKNVHTGDTQVIRA
NFVFVGAGGMALPLLQKTGIVEIRGWGGFPVSGQWLRCTNPDIIEQHAAKVYGKASIGAPPMSVPHLDTRVIDGEKGLLF
GPYAGWTPKFLKKGSYLDLFKSIRPTNLMSYLGVGAQEFGLTKYLITEVMKDQAARMESLREYMPNAKDEDWELVTAGQR
VQAIQPVVGPRFSTLAFGTSLINSADGSVAGILGASPGASIAPAAMLELLERCFGQKMVEWGPTIKDMIPSYGIRLATDQ
KLFNEIWDHTQATLQLDKK
>Mature_498_residues
ADSTTAQHVTDEVDVALIGAGIMSATLGAMLRTLEPGWTQVMFERLDAPAQESSSPWNNAGTGHSALCELNYTPEVKGRV
QIDKALGVNEKFQISRQFWSYQVNEGVLPSPREWINPVPHVSFGRGEDQVAYLKKRYEALAAHPLFPNMQYTDDRAKFAE
MLPLMADGRSEFEKVAISWTDAGTDINYGSQTRQFLKAAEKNGTEIRYGHEVKDIKRDGAKWRVTVKNVHTGDTQVIRAN
FVFVGAGGMALPLLQKTGIVEIRGWGGFPVSGQWLRCTNPDIIEQHAAKVYGKASIGAPPMSVPHLDTRVIDGEKGLLFG
PYAGWTPKFLKKGSYLDLFKSIRPTNLMSYLGVGAQEFGLTKYLITEVMKDQAARMESLREYMPNAKDEDWELVTAGQRV
QAIQPVVGPRFSTLAFGTSLINSADGSVAGILGASPGASIAPAAMLELLERCFGQKMVEWGPTIKDMIPSYGIRLATDQK
LFNEIWDHTQATLQLDKK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MQO family

Homologues:

Organism=Escherichia coli, GI1788539, Length=490, Percent_Identity=50.6122448979592, Blast_Score=489, Evalue=1e-139,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MQO_CORDI (Q6NGL9)

Other databases:

- EMBL:   BX248358
- RefSeq:   NP_939838.1
- ProteinModelPortal:   Q6NGL9
- GeneID:   2650376
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1492
- NMPDR:   fig|257309.1.peg.1429
- HOGENOM:   HBG289663
- OMA:   NALKEYF
- PhylomeDB:   Q6NGL9
- ProtClustDB:   PRK05257
- BioCyc:   CDIP257309:DIP1492-MONOMER
- BRENDA:   1.1.99.16
- HAMAP:   MF_00212
- InterPro:   IPR006231
- TIGRFAMs:   TIGR01320

Pfam domain/function: PF06039 Mqo

EC number: =1.1.5.4

Molecular weight: Translated: 55033; Mature: 54902

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADSTTAQHVTDEVDVALIGAGIMSATLGAMLRTLEPGWTQVMFERLDAPAQESSSPWNN
CCCCCCHHHHHHHHCEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCC
AGTGHSALCELNYTPEVKGRVQIDKALGVNEKFQISRQFWSYQVNEGVLPSPREWINPVP
CCCCCCEEEEECCCCCCCCEEEEHHHCCCCHHHHHHHHHHCEECCCCCCCCCHHHCCCCC
HVSFGRGEDQVAYLKKRYEALAAHPLFPNMQYTDDRAKFAEMLPLMADGRSEFEKVAISW
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHEEEEEE
TDAGTDINYGSQTRQFLKAAEKNGTEIRYGHEVKDIKRDGAKWRVTVKNVHTGDTQVIRA
ECCCCCCCCCHHHHHHHHHHHCCCCEEEECCHHHHHHHCCCEEEEEEEEEECCCCEEEEE
NFVFVGAGGMALPLLQKTGIVEIRGWGGFPVSGQWLRCTNPDIIEQHAAKVYGKASIGAP
EEEEEECCCHHHHHHHCCCEEEEECCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCCC
PMSVPHLDTRVIDGEKGLLFGPYAGWTPKFLKKGSYLDLFKSIRPTNLMSYLGVGAQEFG
CCCCCCCCEEEECCCCCEEECCCCCCCHHHHHCCCHHHHHHHCCHHHHHHHHCCCHHHHH
LTKYLITEVMKDQAARMESLREYMPNAKDEDWELVTAGQRVQAIQPVVGPRFSTLAFGTS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHCCCCHHHHHHHHH
LINSADGSVAGILGASPGASIAPAAMLELLERCFGQKMVEWGPTIKDMIPSYGIRLATDQ
HHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCHHHHHCCCHHHHHCCCCEEEECHH
KLFNEIWDHTQATLQLDKK
HHHHHHHCCCEEEEEECCC
>Mature Secondary Structure 
ADSTTAQHVTDEVDVALIGAGIMSATLGAMLRTLEPGWTQVMFERLDAPAQESSSPWNN
CCCCCHHHHHHHHCEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCC
AGTGHSALCELNYTPEVKGRVQIDKALGVNEKFQISRQFWSYQVNEGVLPSPREWINPVP
CCCCCCEEEEECCCCCCCCEEEEHHHCCCCHHHHHHHHHHCEECCCCCCCCCHHHCCCCC
HVSFGRGEDQVAYLKKRYEALAAHPLFPNMQYTDDRAKFAEMLPLMADGRSEFEKVAISW
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHEEEEEE
TDAGTDINYGSQTRQFLKAAEKNGTEIRYGHEVKDIKRDGAKWRVTVKNVHTGDTQVIRA
ECCCCCCCCCHHHHHHHHHHHCCCCEEEECCHHHHHHHCCCEEEEEEEEEECCCCEEEEE
NFVFVGAGGMALPLLQKTGIVEIRGWGGFPVSGQWLRCTNPDIIEQHAAKVYGKASIGAP
EEEEEECCCHHHHHHHCCCEEEEECCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCCC
PMSVPHLDTRVIDGEKGLLFGPYAGWTPKFLKKGSYLDLFKSIRPTNLMSYLGVGAQEFG
CCCCCCCCEEEECCCCCEEECCCCCCCHHHHHCCCHHHHHHHCCHHHHHHHHCCCHHHHH
LTKYLITEVMKDQAARMESLREYMPNAKDEDWELVTAGQRVQAIQPVVGPRFSTLAFGTS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHCCCCHHHHHHHHH
LINSADGSVAGILGASPGASIAPAAMLELLERCFGQKMVEWGPTIKDMIPSYGIRLATDQ
HHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCHHHHHCCCHHHHHCCCCEEEECHH
KLFNEIWDHTQATLQLDKK
HHHHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14602910