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The map label for this gene is cobO [H]

Identifier: 38234070

GI number: 38234070

Start: 1510411

End: 1511031

Strand: Reverse

Name: cobO [H]

Synonym: DIP1489

Alternate gene names: 38234070

Gene position: 1511031-1510411 (Counterclockwise)

Preceding gene: 38234071

Following gene: 161598673

Centisome position: 60.72

GC content: 49.44

Gene sequence:

>621_bases
ATGCCTCAAGGAAAACTCGATCCAGCTTCGGTTCCAGATGATGGTTTAACTACTCGCCAACGTAGGTTGTTGCCGATTAC
AGCTGTTCATACTGGTCCTGGCAAAGGTAAATCAACAGCTGCTTTTGGTATGGCGCTACGTGCGTGGAATCAAGGTATGA
GCATCGGAGTTTTCCAATTCGTCAAATCCGCAAAATGGCGTGTTGGCGAGGAGAGCGTGTTCAAACAACTAGGCCAATCA
CACATCGATAGTGGGGTAGGGGGACCTGTTGAATGGCACAAGATGGGGGAGGGCTGGTCGTGGTCAAAGAAGCGGGGATC
TGAGGAAGACCATGCTCGTGATGCACGCGAGGGATGGGAAGAGATTAAGCGGCGGTTAGCGTCCCAAACCCATGATTTTT
ATGTACTCGATGAATTTACTTATCCTATAGCGTGGGGTTGGATCGATGTCAACGATGTCGTTGAGACGTTGAAGAATCGA
CCAGGAACTCAACATGTGGTCATCACAGGGCGAAATGCTGCACCGGAGCTTATCGACGTCGCTGATTTGGTTACAGAGAT
GACAAAGATTAAGCATCCGATGGATGTTGGTCGCAAGGGGCAAAAGGGAATCGAATGGTAA

Upstream 100 bases:

>100_bases
AGCGGTTATCGTTTTTTCACTCGCTCATGCGGAAAATATGAAAAAGCATGACTTGCTCGCATGATCAACGACATAACTAC
TGGATGCAAGGGAGACGCAC

Downstream 100 bases:

>100_bases
CAACGCCGGGGTTCGTCATTGCTGCAACCTCATCAGGGTCGGGAAAAACCACAATTGCAACAGGCATGATGGCCGCGTTG
TCTAGAAAGATGCGAGTTGC

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MPQGKLDPASVPDDGLTTRQRRLLPITAVHTGPGKGKSTAAFGMALRAWNQGMSIGVFQFVKSAKWRVGEESVFKQLGQS
HIDSGVGGPVEWHKMGEGWSWSKKRGSEEDHARDAREGWEEIKRRLASQTHDFYVLDEFTYPIAWGWIDVNDVVETLKNR
PGTQHVVITGRNAAPELIDVADLVTEMTKIKHPMDVGRKGQKGIEW

Sequences:

>Translated_206_residues
MPQGKLDPASVPDDGLTTRQRRLLPITAVHTGPGKGKSTAAFGMALRAWNQGMSIGVFQFVKSAKWRVGEESVFKQLGQS
HIDSGVGGPVEWHKMGEGWSWSKKRGSEEDHARDAREGWEEIKRRLASQTHDFYVLDEFTYPIAWGWIDVNDVVETLKNR
PGTQHVVITGRNAAPELIDVADLVTEMTKIKHPMDVGRKGQKGIEW
>Mature_205_residues
PQGKLDPASVPDDGLTTRQRRLLPITAVHTGPGKGKSTAAFGMALRAWNQGMSIGVFQFVKSAKWRVGEESVFKQLGQSH
IDSGVGGPVEWHKMGEGWSWSKKRGSEEDHARDAREGWEEIKRRLASQTHDFYVLDEFTYPIAWGWIDVNDVVETLKNRP
GTQHVVITGRNAAPELIDVADLVTEMTKIKHPMDVGRKGQKGIEW

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=181, Percent_Identity=38.121546961326, Blast_Score=126, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 23028; Mature: 22897

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQGKLDPASVPDDGLTTRQRRLLPITAVHTGPGKGKSTAAFGMALRAWNQGMSIGVFQF
CCCCCCCCCCCCCCCCCHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
VKSAKWRVGEESVFKQLGQSHIDSGVGGPVEWHKMGEGWSWSKKRGSEEDHARDAREGWE
HHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHCCCCHHHHHHHHHHHH
EIKRRLASQTHDFYVLDEFTYPIAWGWIDVNDVVETLKNRPGTQHVVITGRNAAPELIDV
HHHHHHHHCCCCEEEEECCCCCEEEEEECHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH
ADLVTEMTKIKHPMDVGRKGQKGIEW
HHHHHHHHHHCCCHHHCCCCCCCCCC
>Mature Secondary Structure 
PQGKLDPASVPDDGLTTRQRRLLPITAVHTGPGKGKSTAAFGMALRAWNQGMSIGVFQF
CCCCCCCCCCCCCCCCHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
VKSAKWRVGEESVFKQLGQSHIDSGVGGPVEWHKMGEGWSWSKKRGSEEDHARDAREGWE
HHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHCCCCHHHHHHHHHHHH
EIKRRLASQTHDFYVLDEFTYPIAWGWIDVNDVVETLKNRPGTQHVVITGRNAAPELIDV
HHHHHHHHCCCCEEEEECCCCCEEEEEECHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH
ADLVTEMTKIKHPMDVGRKGQKGIEW
HHHHHHHHHHCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]