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The map label for this gene is ahpD

Identifier: 38234004

GI number: 38234004

Start: 1437952

End: 1438476

Strand: Reverse

Name: ahpD

Synonym: DIP1419

Alternate gene names: 38234004

Gene position: 1438476-1437952 (Counterclockwise)

Preceding gene: 38234005

Following gene: 38234001

Centisome position: 57.8

GC content: 47.81

Gene sequence:

>525_bases
ATGTCGTTGGATAACCTCAAATCTGGGCTTCCAGAATATGCAAAAGATCTGAAACTCAACCTTGGTAGCTTGGCACGTTC
TACGGAACTTACTGAGCAGCAATTGTGGGGTACATTCCTTGCAGTAGCGGCGGCTACCCGTAACGAGGCTGTCTTTTCTG
AAATTTCAGAAGAAGCATCTGAGCATTTGAGCGAAGAAGCTATTAACGCAGCCCTTGGTGCAGCGTCGATTATGGCCATG
AACAATGTGGCTTATCGTGCAAAGGGATGGCTCGGCGATGACTACGCTCAGGTAAAAATGGGCCTTCGCATGAACATCAT
CGCAAAGCCAGGTGTGGATAAAGTTGATTTCGAGCTGTGGTCACTAGCAGTTTCTACGGTTAATGGCTGTGAACACTGCA
CCATTGCTCACGAAAAGACTGTCCGTTCCGAAGGGCTAACTAAGGAACAGATCTTTGAAGCGGTCAAGATTGCCGCAACA
CTACAAGGTGTTGCCCAAGCAATCGAGATTGAAGCTTCGCGATAA

Upstream 100 bases:

>100_bases
CACTTCAGTCTGAAGAGGTCTGTGCCTGCAACTGGCAGAAGAACGACCCAACCAAGAACATTGATAAGTTCGCTGAGCTT
GAGAAGGGCCTCAACTAAAA

Downstream 100 bases:

>100_bases
TCAGCCCTAATAAAGGCGTACGTGTGCTCAGTTGCTACATTAGTAGCAACTGAGCACACGTACGCCTTTTGTCTTTCAGC
TGTCGATGGAGAATTTCGCG

Product: hypothetical protein

Products: NA

Alternate protein names: Alkylhydroperoxidase AhpD

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MSLDNLKSGLPEYAKDLKLNLGSLARSTELTEQQLWGTFLAVAAATRNEAVFSEISEEASEHLSEEAINAALGAASIMAM
NNVAYRAKGWLGDDYAQVKMGLRMNIIAKPGVDKVDFELWSLAVSTVNGCEHCTIAHEKTVRSEGLTKEQIFEAVKIAAT
LQGVAQAIEIEASR

Sequences:

>Translated_174_residues
MSLDNLKSGLPEYAKDLKLNLGSLARSTELTEQQLWGTFLAVAAATRNEAVFSEISEEASEHLSEEAINAALGAASIMAM
NNVAYRAKGWLGDDYAQVKMGLRMNIIAKPGVDKVDFELWSLAVSTVNGCEHCTIAHEKTVRSEGLTKEQIFEAVKIAAT
LQGVAQAIEIEASR
>Mature_173_residues
SLDNLKSGLPEYAKDLKLNLGSLARSTELTEQQLWGTFLAVAAATRNEAVFSEISEEASEHLSEEAINAALGAASIMAMN
NVAYRAKGWLGDDYAQVKMGLRMNIIAKPGVDKVDFELWSLAVSTVNGCEHCTIAHEKTVRSEGLTKEQIFEAVKIAATL
QGVAQAIEIEASR

Specific function: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity

COG id: COG2128

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AhpD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AHPD_CORDI (Q6NGT4)

Other databases:

- EMBL:   BX248358
- RefSeq:   NP_939771.1
- HSSP:   P0A5N4
- ProteinModelPortal:   Q6NGT4
- SMR:   Q6NGT4
- PeroxiBase:   4585
- GeneID:   2649693
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1419
- NMPDR:   fig|257309.1.peg.1362
- HOGENOM:   HBG414634
- OMA:   PEYAKDL
- ProtClustDB:   CLSK2485789
- BioCyc:   CDIP257309:DIP1419-MONOMER
- HAMAP:   MF_01676
- InterPro:   IPR004674
- InterPro:   IPR004675
- InterPro:   IPR003779
- TIGRFAMs:   TIGR00777
- TIGRFAMs:   TIGR00778

Pfam domain/function: PF02627 CMD

EC number: =1.11.1.15

Molecular weight: Translated: 18815; Mature: 18683

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: ACT_SITE 130-130 ACT_SITE 133-133

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDNLKSGLPEYAKDLKLNLGSLARSTELTEQQLWGTFLAVAAATRNEAVFSEISEEAS
CCCHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
EHLSEEAINAALGAASIMAMNNVAYRAKGWLGDDYAQVKMGLRMNIIAKPGVDKVDFELW
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCEEEEEECCCCCHHHHHHH
SLAVSTVNGCEHCTIAHEKTVRSEGLTKEQIFEAVKIAATLQGVAQAIEIEASR
HHHHHHHCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLDNLKSGLPEYAKDLKLNLGSLARSTELTEQQLWGTFLAVAAATRNEAVFSEISEEAS
CCHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
EHLSEEAINAALGAASIMAMNNVAYRAKGWLGDDYAQVKMGLRMNIIAKPGVDKVDFELW
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCEEEEEECCCCCHHHHHHH
SLAVSTVNGCEHCTIAHEKTVRSEGLTKEQIFEAVKIAATLQGVAQAIEIEASR
HHHHHHHCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910