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The map label for this gene is dtd [H]

Identifier: 38233997

GI number: 38233997

Start: 1429600

End: 1430037

Strand: Direct

Name: dtd [H]

Synonym: DIP1412

Alternate gene names: 38233997

Gene position: 1429600-1430037 (Clockwise)

Preceding gene: 38233996

Following gene: 38233998

Centisome position: 57.45

GC content: 51.37

Gene sequence:

>438_bases
GTGCGAGCTGTATTGACTCGAGTACTCAGCGCTTCTGTGACCGTCGATAATGTTGTCGTTGGAGAAATAAACTGTCCTTC
TACTGGAGGGATTCTTGCTTTGGTCGGAGTCGGCCGCAATGACAGTGCTTCCGCATGGGAAACGATGACTCGCAAGATTG
CAGAACTTCGAATCCTCAAAGGGGAACAAAGCGTAGAAACTGCCCATGCACCCGTATTGTTGGTGAGCCAGTTCACTTTG
ATGGGGCGTACCGCAAAAGGACGCCGTCCTTCTTGGTTCGATGCGGCTCCAAGCGATCCCGCCGAAGAAACCATCACCAA
GATCGCAAACGGACTGCGATCCCGAGGAATAACCGTTTATGAAGGAAGGTTCAGAGCAGATATGCAGGTGGAATCCGTCA
ATGACGGACCGTTCACTGTAATTGTCGAATGCCCATAG

Upstream 100 bases:

>100_bases
GAGTCCTTTGTTGATGCCATTATTGATCCAGTCGTGGCCCTTGTCCGCCACGGTATTCTTCTACCAGCCGAGATCACAAA
GGGATGGTGACTACTCAACC

Downstream 100 bases:

>100_bases
TTTCCCCACACATGGGGGTAATGGAACTAGATTTATCGATTCGCCGTTGTTCCATGTGTAGCAACGAGAGCTAGGAGGTC
ATTATGACAAGCCCTTCCGA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MRAVLTRVLSASVTVDNVVVGEINCPSTGGILALVGVGRNDSASAWETMTRKIAELRILKGEQSVETAHAPVLLVSQFTL
MGRTAKGRRPSWFDAAPSDPAEETITKIANGLRSRGITVYEGRFRADMQVESVNDGPFTVIVECP

Sequences:

>Translated_145_residues
MRAVLTRVLSASVTVDNVVVGEINCPSTGGILALVGVGRNDSASAWETMTRKIAELRILKGEQSVETAHAPVLLVSQFTL
MGRTAKGRRPSWFDAAPSDPAEETITKIANGLRSRGITVYEGRFRADMQVESVNDGPFTVIVECP
>Mature_145_residues
MRAVLTRVLSASVTVDNVVVGEINCPSTGGILALVGVGRNDSASAWETMTRKIAELRILKGEQSVETAHAPVLLVSQFTL
MGRTAKGRRPSWFDAAPSDPAEETITKIANGLRSRGITVYEGRFRADMQVESVNDGPFTVIVECP

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=153, Percent_Identity=36.6013071895425, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790320, Length=144, Percent_Identity=38.8888888888889, Blast_Score=86, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI115533292, Length=151, Percent_Identity=34.4370860927152, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319982, Length=151, Percent_Identity=33.7748344370861, Blast_Score=81, Evalue=7e-17,
Organism=Drosophila melanogaster, GI281361569, Length=152, Percent_Identity=36.1842105263158, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 15587; Mature: 15587

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVLTRVLSASVTVDNVVVGEINCPSTGGILALVGVGRNDSASAWETMTRKIAELRILK
CHHHHHHHHHCCCEECEEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHEEC
GEQSVETAHAPVLLVSQFTLMGRTAKGRRPSWFDAAPSDPAEETITKIANGLRSRGITVY
CCCCCHHHCCCEEEEEHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEE
EGRFRADMQVESVNDGPFTVIVECP
CCCEECCEEEEECCCCCEEEEEECC
>Mature Secondary Structure
MRAVLTRVLSASVTVDNVVVGEINCPSTGGILALVGVGRNDSASAWETMTRKIAELRILK
CHHHHHHHHHCCCEECEEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHEEC
GEQSVETAHAPVLLVSQFTLMGRTAKGRRPSWFDAAPSDPAEETITKIANGLRSRGITVY
CCCCCHHHCCCEEEEEHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEE
EGRFRADMQVESVNDGPFTVIVECP
CCCEECCEEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA