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The map label for this gene is iap [H]

Identifier: 38233866

GI number: 38233866

Start: 1288281

End: 1289999

Strand: Reverse

Name: iap [H]

Synonym: DIP1281

Alternate gene names: 38233866

Gene position: 1289999-1288281 (Counterclockwise)

Preceding gene: 38233873

Following gene: 38233865

Centisome position: 51.84

GC content: 48.57

Gene sequence:

>1719_bases
GTGACTATACGATCGTCTATGTCTAGTCGTACCACTACGAAAGTGATGCGCGGCTTGATCGCATCTGGATTATCGATTGC
ATGTCTCGGGGCTACTTCTACTGTGGTAGCAGAGCCTGCAAACCCTTCAGACACTGAAATAGCTTCTGCAGATAGCCAAG
TAGGCGTAGCCCAAGGTGAGGTGTCAAAGCTAGTAGCATCGGTTTCTAATTCAGACTCTGAAATCGCAGCTTTGGAACTC
GAAATGGGTGGATTGCGCGAGGCAGTTAACAAAGCGCTGGTTGATCTGCATGATGCACAAAGTTCAGCTGAACGGGCTCG
GCAAGGCGTGACTGTGGCTCGCAAGAAGCTTGACGATATTCAAGCGGAGATATTAAAAGCCCAAAAAACGCTCGATGAAA
TTTCTCGTAGTGCTTATCGGCAGGGGGCAGTGCCAAGTGGTGTTGCAGGTGTTTCCGGTAAGGCTACTTCAGAAGAAGCG
TTGGATCGCCAAACTTACCTACGTACTAACGCTCAAAAACAACGCGAAGCGGTAGATGCTCTCGACAGGTTACGAACCGA
GCAAGCAAATGAAGAGTCGCGACTTCGTGAGGTCAAGAATCTTGCAGAAAAGCGGGAATCTGAAGCTGAAAGTGCTAAGG
CTTCAGCTCAACAAGCAATTGATTCTTCTAATTCAAAGCTGGAAGAAAATCTCCGTAAACGAGCTGAGTTAATTAGTAAG
CGCGAAGAAGCCCAGCGTGGTCTCGATTCTGCTCGGGGTAATGCCGATTCGTTACGTCAACAACGATCAGAATACGAGGA
ATACAAGCGGGCAGAAGAAGCTCGAAAGAAAGCAGAAGCAGAAGCTGCCGCAGCTGAAAAGGCACGTCAGGAAGCTGAAG
CTGCTCGTAAGGCGAAAGAAGAGGCTGCTAGGATTGCAGCGGAAGCTGCTCGAAAAGCCGCTGACGAAGCTGCCCGAAAG
GTTGCGGCGGAAAAAGCAGAAAAAGCACGTCAAGATGCAGAAAAAGCTGCGGAAGCAGCTCAGGCTCAAGCCGAGGCTGA
AAGACAGGCATCAGAGAATCGCCGTTCTACAGCGAACGATTCTGCTCGCGCCGCTGCTGCGTTGATTGAGGCTGCAACGC
CAAATCATGCGTCTTTAGATGATCCATATGATTCGAATAGCCAAGACGGAAACTACATTGCTGCTGTAGAAAAAGAAGAT
AACGATTCTTCTATTCTTGATGACCTGGACGTTGCTCAGGTTGATTCGATGGAGGATGTATCTAAAAAGGCATCTGCGTT
AGTAGAAAACGCGAGCCGAAGCGAAAAGATTGAAATAGTCATCTCAAGGGCAATGGCTTATATTGGAACTCCTTACGCAT
GGGGCGGCGGTAATGCGAGTGGCCCAACGCAAGGTATTCGAGACGGCGGCGTAGCTGATTCTTTCGGTGATTTTAATAAA
ATTGGATTCGACTGTTCGGGGCTAACTTTGTATGCATTTGCTGGTGTAGGTATAGCTTTGCCTCATTACACTGGTTACCA
GTACCAAAAGGGAACCAAAGTTGATCCCTCCAATATGCAGCGCGGAGATCTTATTTTCTACGGCCCTAATGCCGAGTACC
ATGTGGCCATCTATCTTGGTGATGGAACAATGCTAGAGGCTCCGCAATCAGGATCAAGCGTTAAAGTTTCTCCAGTTCGT
TGGTCTGGAATGAGTCCATACGCTGTGCGCCTCATTTAA

Upstream 100 bases:

>100_bases
GATTACTCAAGTCATAATTCGAAGATCGAGATTCGAGTCACTCAACCTTGTTATTGGTTTGCATGGAAACACCATGTGAA
ACGTTTATAGGAGTAGCCCT

Downstream 100 bases:

>100_bases
GCAGTAAATATTGAATAAACGGGTGAAAGTCTCGACCGTGAGGATAACGGTTGCACAAGACTTTCACCCTTTAGTGTTAA
GCTAACTGCTTATGGTCGAA

Product: putative invasion protein

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 572; Mature: 571

Protein sequence:

>572_residues
MTIRSSMSSRTTTKVMRGLIASGLSIACLGATSTVVAEPANPSDTEIASADSQVGVAQGEVSKLVASVSNSDSEIAALEL
EMGGLREAVNKALVDLHDAQSSAERARQGVTVARKKLDDIQAEILKAQKTLDEISRSAYRQGAVPSGVAGVSGKATSEEA
LDRQTYLRTNAQKQREAVDALDRLRTEQANEESRLREVKNLAEKRESEAESAKASAQQAIDSSNSKLEENLRKRAELISK
REEAQRGLDSARGNADSLRQQRSEYEEYKRAEEARKKAEAEAAAAEKARQEAEAARKAKEEAARIAAEAARKAADEAARK
VAAEKAEKARQDAEKAAEAAQAQAEAERQASENRRSTANDSARAAAALIEAATPNHASLDDPYDSNSQDGNYIAAVEKED
NDSSILDDLDVAQVDSMEDVSKKASALVENASRSEKIEIVISRAMAYIGTPYAWGGGNASGPTQGIRDGGVADSFGDFNK
IGFDCSGLTLYAFAGVGIALPHYTGYQYQKGTKVDPSNMQRGDLIFYGPNAEYHVAIYLGDGTMLEAPQSGSSVKVSPVR
WSGMSPYAVRLI

Sequences:

>Translated_572_residues
MTIRSSMSSRTTTKVMRGLIASGLSIACLGATSTVVAEPANPSDTEIASADSQVGVAQGEVSKLVASVSNSDSEIAALEL
EMGGLREAVNKALVDLHDAQSSAERARQGVTVARKKLDDIQAEILKAQKTLDEISRSAYRQGAVPSGVAGVSGKATSEEA
LDRQTYLRTNAQKQREAVDALDRLRTEQANEESRLREVKNLAEKRESEAESAKASAQQAIDSSNSKLEENLRKRAELISK
REEAQRGLDSARGNADSLRQQRSEYEEYKRAEEARKKAEAEAAAAEKARQEAEAARKAKEEAARIAAEAARKAADEAARK
VAAEKAEKARQDAEKAAEAAQAQAEAERQASENRRSTANDSARAAAALIEAATPNHASLDDPYDSNSQDGNYIAAVEKED
NDSSILDDLDVAQVDSMEDVSKKASALVENASRSEKIEIVISRAMAYIGTPYAWGGGNASGPTQGIRDGGVADSFGDFNK
IGFDCSGLTLYAFAGVGIALPHYTGYQYQKGTKVDPSNMQRGDLIFYGPNAEYHVAIYLGDGTMLEAPQSGSSVKVSPVR
WSGMSPYAVRLI
>Mature_571_residues
TIRSSMSSRTTTKVMRGLIASGLSIACLGATSTVVAEPANPSDTEIASADSQVGVAQGEVSKLVASVSNSDSEIAALELE
MGGLREAVNKALVDLHDAQSSAERARQGVTVARKKLDDIQAEILKAQKTLDEISRSAYRQGAVPSGVAGVSGKATSEEAL
DRQTYLRTNAQKQREAVDALDRLRTEQANEESRLREVKNLAEKRESEAESAKASAQQAIDSSNSKLEENLRKRAELISKR
EEAQRGLDSARGNADSLRQQRSEYEEYKRAEEARKKAEAEAAAAEKARQEAEAARKAKEEAARIAAEAARKAADEAARKV
AAEKAEKARQDAEKAAEAAQAQAEAERQASENRRSTANDSARAAAALIEAATPNHASLDDPYDSNSQDGNYIAAVEKEDN
DSSILDDLDVAQVDSMEDVSKKASALVENASRSEKIEIVISRAMAYIGTPYAWGGGNASGPTQGIRDGGVADSFGDFNKI
GFDCSGLTLYAFAGVGIALPHYTGYQYQKGTKVDPSNMQRGDLIFYGPNAEYHVAIYLGDGTMLEAPQSGSSVKVSPVRW
SGMSPYAVRLI

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1786421, Length=126, Percent_Identity=32.5396825396825, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1787944, Length=126, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 61150; Mature: 61019

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRSSMSSRTTTKVMRGLIASGLSIACLGATSTVVAEPANPSDTEIASADSQVGVAQGE
CCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCCCCCCHHHCCCCCCCCHHHH
VSKLVASVSNSDSEIAALELEMGGLREAVNKALVDLHDAQSSAERARQGVTVARKKLDDI
HHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAEILKAQKTLDEISRSAYRQGAVPSGVAGVSGKATSEEALDRQTYLRTNAQKQREAVDA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LDRLRTEQANEESRLREVKNLAEKRESEAESAKASAQQAIDSSNSKLEENLRKRAELISK
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
REEAQRGLDSARGNADSLRQQRSEYEEYKRAEEARKKAEAEAAAAEKARQEAEAARKAKE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAARIAAEAARKAADEAARKVAAEKAEKARQDAEKAAEAAQAQAEAERQASENRRSTAND
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
SARAAAALIEAATPNHASLDDPYDSNSQDGNYIAAVEKEDNDSSILDDLDVAQVDSMEDV
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHCCCHHHHCCHHHH
SKKASALVENASRSEKIEIVISRAMAYIGTPYAWGGGNASGPTQGIRDGGVADSFGDFNK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
IGFDCSGLTLYAFAGVGIALPHYTGYQYQKGTKVDPSNMQRGDLIFYGPNAEYHVAIYLG
CCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEC
DGTMLEAPQSGSSVKVSPVRWSGMSPYAVRLI
CCCEEECCCCCCCEEEECEEECCCCCEEEEEC
>Mature Secondary Structure 
TIRSSMSSRTTTKVMRGLIASGLSIACLGATSTVVAEPANPSDTEIASADSQVGVAQGE
CCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCCCCCCHHHCCCCCCCCHHHH
VSKLVASVSNSDSEIAALELEMGGLREAVNKALVDLHDAQSSAERARQGVTVARKKLDDI
HHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAEILKAQKTLDEISRSAYRQGAVPSGVAGVSGKATSEEALDRQTYLRTNAQKQREAVDA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LDRLRTEQANEESRLREVKNLAEKRESEAESAKASAQQAIDSSNSKLEENLRKRAELISK
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
REEAQRGLDSARGNADSLRQQRSEYEEYKRAEEARKKAEAEAAAAEKARQEAEAARKAKE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAARIAAEAARKAADEAARKVAAEKAEKARQDAEKAAEAAQAQAEAERQASENRRSTAND
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
SARAAAALIEAATPNHASLDDPYDSNSQDGNYIAAVEKEDNDSSILDDLDVAQVDSMEDV
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHCCCHHHHCCHHHH
SKKASALVENASRSEKIEIVISRAMAYIGTPYAWGGGNASGPTQGIRDGGVADSFGDFNK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
IGFDCSGLTLYAFAGVGIALPHYTGYQYQKGTKVDPSNMQRGDLIFYGPNAEYHVAIYLG
CCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEC
DGTMLEAPQSGSSVKVSPVRWSGMSPYAVRLI
CCCEEECCCCCCCEEEECEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1514809; 1459966 [H]