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The map label for this gene is apeB [H]

Identifier: 38233838

GI number: 38233838

Start: 1253482

End: 1254840

Strand: Reverse

Name: apeB [H]

Synonym: DIP1250

Alternate gene names: 38233838

Gene position: 1254840-1253482 (Counterclockwise)

Preceding gene: 38233841

Following gene: 38233837

Centisome position: 50.42

GC content: 47.53

Gene sequence:

>1359_bases
GTGATTATGGATTCATCATTTTCTGATCATCGCGGTATCCCTATAGCTGATCTGGACCATAGCGAACACGTTCGTTCACA
AACGGAAGCTATGGCTTGGGAACTGGTTAGTTTTATCGCTAATTCCCCTAGTTCATTTCATGCTGCTCAGCAAGGCGCAC
AATTGCTACAAGAAGCGGGATTTCATCAAGTCGATGAAACTGCCGATTGGGATAGCACCCTAGGCGGTCATTTTATGATT
CGCGGTGGGGCACTGATGGCATGGTATGTCCCGACGTCGGCTGATACTTCATCGGGTTTTAGGATCATAGGTGCGCATAA
TGATTCACCCGGCTTTAAGCTGAAATATCACCCTGATCTTATGTCTGCTGGATGGCAACAAGCATCTGTAGAGGTCTATG
GTGGTCCTATTTTAGCTTCTTGGTTCGATCGTGAATTAGTTTTAGCCGGTCGCATCGGGCTTATCGACGGCTCCACTCGC
ACTGTAACTACTGCTCCTGTGCTAAGAATTCCGCACCTTGCTATTCATCTAGATCGAGATGCAAACACGTCGTTATCTAT
TGATCGTCAACGGCATACCCAACCAATATTTGCCGTCGGCGAACCAGATTTATCGATTATGGATGTGATCGCAACTGCAG
CAGGCGTTAACAAGGAAGAGATTATTTCACATGATTTGATTACGGCAGATGCTCAGCCTGGTGAAATTTTTGGCGCAACC
TCTGATTTTCTTGCTGCAGGGCGATTGGATAATCTTTCCAGCGTTTTTCCTGGGCTTAAAGCATTTGTGGAGGCAGCTGA
AGATAATGTGCTTGGCCGTGCACCGATGAAGGACATTCTTGTTTTCGCCGCTTTTGACCACGAGGAAGTCGGTAGTGCCA
CAACAACTGGGGCTGCCGGACCTATTTTAGAAGACGTACTAACTAGAACAGCTGCTGGGTTAGGTGCAGACGCTGAAAAA
ACAAAGCAAATGATCACACGCTCCACGTGCATTTCAGTAGACGCAGCTCACTCAATTCATCCAAATTATGCGCATCAACA
TGATCCTTTGAATCATCCTGTTATGGGTGGCGGCCCTACACTGAAGGTCAATGCGAACCAACGTTATGCGTCCAATACCG
AAACAGAGGCAATGTGGGTACGCGCTTGTATGAAAGCCGGAAGTAGTCATCAAGTCTTCGTAGGCAATAACAGCGTCCCA
TGTGGTTCGACTATTGGCCCCATAACGGCAACTCGGCTGGGTATTCCTACTGTAGATGTCGGAGTTCCGTTGCTTTCCAT
GCACTCTGCTCGAGAATTAGCCAGCACCACAGATATCTATTGGTTATCACGGTGTCTGCACGCGTATCTGGTAGGTTAA

Upstream 100 bases:

>100_bases
AAGTTCAATATTGTATGAGCCTGGACCGACATTTGCATGTTGCTAGTCACAAGCTTGAAAGGAAACACGCGTTGTCTAAA
GGATGGGAAGGTTAGACTGG

Downstream 100 bases:

>100_bases
ATTCTCATGGCAAACTCTGGACCATTTCAGCCTGGTGATCGTGTGCAACTCACAGATCCCAAGCGCCGGCATGCAACGAT
AGTTCTTGAAACAGGCGGTG

Product: putative aminopeptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MIMDSSFSDHRGIPIADLDHSEHVRSQTEAMAWELVSFIANSPSSFHAAQQGAQLLQEAGFHQVDETADWDSTLGGHFMI
RGGALMAWYVPTSADTSSGFRIIGAHNDSPGFKLKYHPDLMSAGWQQASVEVYGGPILASWFDRELVLAGRIGLIDGSTR
TVTTAPVLRIPHLAIHLDRDANTSLSIDRQRHTQPIFAVGEPDLSIMDVIATAAGVNKEEIISHDLITADAQPGEIFGAT
SDFLAAGRLDNLSSVFPGLKAFVEAAEDNVLGRAPMKDILVFAAFDHEEVGSATTTGAAGPILEDVLTRTAAGLGADAEK
TKQMITRSTCISVDAAHSIHPNYAHQHDPLNHPVMGGGPTLKVNANQRYASNTETEAMWVRACMKAGSSHQVFVGNNSVP
CGSTIGPITATRLGIPTVDVGVPLLSMHSARELASTTDIYWLSRCLHAYLVG

Sequences:

>Translated_452_residues
MIMDSSFSDHRGIPIADLDHSEHVRSQTEAMAWELVSFIANSPSSFHAAQQGAQLLQEAGFHQVDETADWDSTLGGHFMI
RGGALMAWYVPTSADTSSGFRIIGAHNDSPGFKLKYHPDLMSAGWQQASVEVYGGPILASWFDRELVLAGRIGLIDGSTR
TVTTAPVLRIPHLAIHLDRDANTSLSIDRQRHTQPIFAVGEPDLSIMDVIATAAGVNKEEIISHDLITADAQPGEIFGAT
SDFLAAGRLDNLSSVFPGLKAFVEAAEDNVLGRAPMKDILVFAAFDHEEVGSATTTGAAGPILEDVLTRTAAGLGADAEK
TKQMITRSTCISVDAAHSIHPNYAHQHDPLNHPVMGGGPTLKVNANQRYASNTETEAMWVRACMKAGSSHQVFVGNNSVP
CGSTIGPITATRLGIPTVDVGVPLLSMHSARELASTTDIYWLSRCLHAYLVG
>Mature_452_residues
MIMDSSFSDHRGIPIADLDHSEHVRSQTEAMAWELVSFIANSPSSFHAAQQGAQLLQEAGFHQVDETADWDSTLGGHFMI
RGGALMAWYVPTSADTSSGFRIIGAHNDSPGFKLKYHPDLMSAGWQQASVEVYGGPILASWFDRELVLAGRIGLIDGSTR
TVTTAPVLRIPHLAIHLDRDANTSLSIDRQRHTQPIFAVGEPDLSIMDVIATAAGVNKEEIISHDLITADAQPGEIFGAT
SDFLAAGRLDNLSSVFPGLKAFVEAAEDNVLGRAPMKDILVFAAFDHEEVGSATTTGAAGPILEDVLTRTAAGLGADAEK
TKQMITRSTCISVDAAHSIHPNYAHQHDPLNHPVMGGGPTLKVNANQRYASNTETEAMWVRACMKAGSSHQVFVGNNSVP
CGSTIGPITATRLGIPTVDVGVPLLSMHSARELASTTDIYWLSRCLHAYLVG

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=445, Percent_Identity=36.1797752808989, Blast_Score=271, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI17552916, Length=439, Percent_Identity=34.624145785877, Blast_Score=224, Evalue=7e-59,
Organism=Saccharomyces cerevisiae, GI6321905, Length=461, Percent_Identity=32.7548806941432, Blast_Score=248, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6322746, Length=445, Percent_Identity=28.5393258426966, Blast_Score=169, Evalue=8e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022984
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 48351; Mature: 48351

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMDSSFSDHRGIPIADLDHSEHVRSQTEAMAWELVSFIANSPSSFHAAQQGAQLLQEAG
CCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
FHQVDETADWDSTLGGHFMIRGGALMAWYVPTSADTSSGFRIIGAHNDSPGFKLKYHPDL
CCCCCCCCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCEEEEEECCCCCCEEEEECCCH
MSAGWQQASVEVYGGPILASWFDRELVLAGRIGLIDGSTRTVTTAPVLRIPHLAIHLDRD
HHCCCCCCEEEEECCEEEEHHCCCEEEEECEEEEECCCCCEEEECCCEECCEEEEEECCC
ANTSLSIDRQRHTQPIFAVGEPDLSIMDVIATAAGVNKEEIISHDLITADAQPGEIFGAT
CCCCEEECHHHCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHEEECCCCCCCEECCC
SDFLAAGRLDNLSSVFPGLKAFVEAAEDNVLGRAPMKDILVFAAFDHEEVGSATTTGAAG
HHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECHHHCCCCCCCCCCC
PILEDVLTRTAAGLGADAEKTKQMITRSTCISVDAAHSIHPNYAHQHDPLNHPVMGGGPT
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCE
LKVNANQRYASNTETEAMWVRACMKAGSSHQVFVGNNSVPCGSTIGPITATRLGIPTVDV
EEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHCCCCCHHC
GVPLLSMHSARELASTTDIYWLSRCLHAYLVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIMDSSFSDHRGIPIADLDHSEHVRSQTEAMAWELVSFIANSPSSFHAAQQGAQLLQEAG
CCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
FHQVDETADWDSTLGGHFMIRGGALMAWYVPTSADTSSGFRIIGAHNDSPGFKLKYHPDL
CCCCCCCCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCEEEEEECCCCCCEEEEECCCH
MSAGWQQASVEVYGGPILASWFDRELVLAGRIGLIDGSTRTVTTAPVLRIPHLAIHLDRD
HHCCCCCCEEEEECCEEEEHHCCCEEEEECEEEEECCCCCEEEECCCEECCEEEEEECCC
ANTSLSIDRQRHTQPIFAVGEPDLSIMDVIATAAGVNKEEIISHDLITADAQPGEIFGAT
CCCCEEECHHHCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHEEECCCCCCCEECCC
SDFLAAGRLDNLSSVFPGLKAFVEAAEDNVLGRAPMKDILVFAAFDHEEVGSATTTGAAG
HHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECHHHCCCCCCCCCCC
PILEDVLTRTAAGLGADAEKTKQMITRSTCISVDAAHSIHPNYAHQHDPLNHPVMGGGPT
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCE
LKVNANQRYASNTETEAMWVRACMKAGSSHQVFVGNNSVPCGSTIGPITATRLGIPTVDV
EEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHCCCCCHHC
GVPLLSMHSARELASTTDIYWLSRCLHAYLVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]