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The map label for this gene is yeiE [H]

Identifier: 37680802

GI number: 37680802

Start: 2648798

End: 2649694

Strand: Direct

Name: yeiE [H]

Synonym: VV2618

Alternate gene names: 37680802

Gene position: 2648798-2649694 (Clockwise)

Preceding gene: 37680800

Following gene: 37680803

Centisome position: 78.96

GC content: 50.39

Gene sequence:

>897_bases
ATGGCAAGTCACATTTCTCTGAAACAACTCAAAGTGTTTACCACCATCACTCAGCACAACACGCTCACCGCCGCTTCGGA
AAGTCTCTTTCTTTCCAAAGCGGCAGTGAGCATGGCGCTGTCCGAGTTGGAGAAGCAAATTGGTCATCATCTGTTTGATC
GCGTTAATAACCGTTTGATTCTCAATCAAGAAGGGCAAAAACTGTTGCCATTGGCCGATGAGCTGTTGAGCCGAGCCAGC
GCGATTGAGTCGCTGTTTGATCAAGACATGACGCTGTCAGGCCAACTTCGTATAGGCGCCAGCGACACCATCGGCAACCA
AGTTGCGCCCTATTTGCTCAGCGATTTTCGCCGCCACACTCAGCATCAAGCACAGAGCCTGTTCATTTCTAACTCGGCGC
AGATCTGCGATATGTTAGTGGATTACGAGCTTGATATCGCCCTGATTGAAGGCAAAACACTGCATCCCGAGCTCAATGCG
ACCCAATTTAGCGAAGATGAAATGTGTGTCATTTGTCCGCCCGATTTTCCCCTTGAACTGAATGGCTCAATCTCACTCAC
TGAGCTGGAGAACAGTCAGTGGATTTTGCGCGAAGCCGGCTCTGGCTCGCGTGAGTTTTTCCATCGAGTCATCGCGCCAC
GCATTGAACATTGGCATGAAGCCTTTCAGCTCAACACCACCGAAGCGTTGATCAATTCGGTTTCCGCAGGACTTGGGCTT
GGTTGCTTATCCCGTCTCTCGGCTGACCATGCCGTGCGAGATGGTCGCGTCAAAATGATCCCGATGCCGCTCGATATGAA
GCGCCGCTTTTGGCTGCTGGTGCACAAAGAAAAGTATCAAAGTCCGTTACTTAAAGCCTTTATCGATTTTTGCCATCATT
GGCATCCCGAACGATAG

Upstream 100 bases:

>100_bases
CAACAAGGCTATCTTTGTATGGCGCTATTTTATGCTTGCTTAATGTTTGAAGATATCTAATTATTTAGAACCAACGTTCA
AAATTATTTAACGAGAGAGC

Downstream 100 bases:

>100_bases
CGGAATTCAGCTCTCATTTTGACGCGAGTCAATGGACATTACTGATGAAAAACTGTATAAACACACAGTACAAATTCTGG
ACTATTTAACTTAGAGGATT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MASHISLKQLKVFTTITQHNTLTAASESLFLSKAAVSMALSELEKQIGHHLFDRVNNRLILNQEGQKLLPLADELLSRAS
AIESLFDQDMTLSGQLRIGASDTIGNQVAPYLLSDFRRHTQHQAQSLFISNSAQICDMLVDYELDIALIEGKTLHPELNA
TQFSEDEMCVICPPDFPLELNGSISLTELENSQWILREAGSGSREFFHRVIAPRIEHWHEAFQLNTTEALINSVSAGLGL
GCLSRLSADHAVRDGRVKMIPMPLDMKRRFWLLVHKEKYQSPLLKAFIDFCHHWHPER

Sequences:

>Translated_298_residues
MASHISLKQLKVFTTITQHNTLTAASESLFLSKAAVSMALSELEKQIGHHLFDRVNNRLILNQEGQKLLPLADELLSRAS
AIESLFDQDMTLSGQLRIGASDTIGNQVAPYLLSDFRRHTQHQAQSLFISNSAQICDMLVDYELDIALIEGKTLHPELNA
TQFSEDEMCVICPPDFPLELNGSISLTELENSQWILREAGSGSREFFHRVIAPRIEHWHEAFQLNTTEALINSVSAGLGL
GCLSRLSADHAVRDGRVKMIPMPLDMKRRFWLLVHKEKYQSPLLKAFIDFCHHWHPER
>Mature_297_residues
ASHISLKQLKVFTTITQHNTLTAASESLFLSKAAVSMALSELEKQIGHHLFDRVNNRLILNQEGQKLLPLADELLSRASA
IESLFDQDMTLSGQLRIGASDTIGNQVAPYLLSDFRRHTQHQAQSLFISNSAQICDMLVDYELDIALIEGKTLHPELNAT
QFSEDEMCVICPPDFPLELNGSISLTELENSQWILREAGSGSREFFHRVIAPRIEHWHEAFQLNTTEALINSVSAGLGLG
CLSRLSADHAVRDGRVKMIPMPLDMKRRFWLLVHKEKYQSPLLKAFIDFCHHWHPER

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788481, Length=289, Percent_Identity=37.0242214532872, Blast_Score=194, Evalue=5e-51,
Organism=Escherichia coli, GI1788748, Length=243, Percent_Identity=25.1028806584362, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI87082132, Length=290, Percent_Identity=21.7241379310345, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI157672245, Length=290, Percent_Identity=25.8620689655172, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787879, Length=298, Percent_Identity=25.503355704698, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786401, Length=301, Percent_Identity=23.2558139534884, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787806, Length=295, Percent_Identity=22.3728813559322, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI145693193, Length=257, Percent_Identity=24.124513618677, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI145693105, Length=287, Percent_Identity=20.5574912891986, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788296, Length=294, Percent_Identity=22.7891156462585, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788887, Length=295, Percent_Identity=22.0338983050847, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33691; Mature: 33560

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASHISLKQLKVFTTITQHNTLTAASESLFLSKAAVSMALSELEKQIGHHLFDRVNNRLI
CCCCCCHHHHHEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
LNQEGQKLLPLADELLSRASAIESLFDQDMTLSGQLRIGASDTIGNQVAPYLLSDFRRHT
ECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
QHQAQSLFISNSAQICDMLVDYELDIALIEGKTLHPELNATQFSEDEMCVICPPDFPLEL
HHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCEECCCCCCCCCCCCCEEEECCCCCCEEE
NGSISLTELENSQWILREAGSGSREFFHRVIAPRIEHWHEAFQLNTTEALINSVSAGLGL
CCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHH
GCLSRLSADHAVRDGRVKMIPMPLDMKRRFWLLVHKEKYQSPLLKAFIDFCHHWHPER
HHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEEHHHHCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ASHISLKQLKVFTTITQHNTLTAASESLFLSKAAVSMALSELEKQIGHHLFDRVNNRLI
CCCCCHHHHHEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
LNQEGQKLLPLADELLSRASAIESLFDQDMTLSGQLRIGASDTIGNQVAPYLLSDFRRHT
ECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
QHQAQSLFISNSAQICDMLVDYELDIALIEGKTLHPELNATQFSEDEMCVICPPDFPLEL
HHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCEECCCCCCCCCCCCCEEEECCCCCCEEE
NGSISLTELENSQWILREAGSGSREFFHRVIAPRIEHWHEAFQLNTTEALINSVSAGLGL
CCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHH
GCLSRLSADHAVRDGRVKMIPMPLDMKRRFWLLVHKEKYQSPLLKAFIDFCHHWHPER
HHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEEHHHHCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]