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The map label for this gene is wrbA [H]

Identifier: 37680694

GI number: 37680694

Start: 2540602

End: 2541177

Strand: Direct

Name: wrbA [H]

Synonym: VV2510

Alternate gene names: 37680694

Gene position: 2540602-2541177 (Clockwise)

Preceding gene: 37680693

Following gene: 37680695

Centisome position: 75.74

GC content: 48.44

Gene sequence:

>576_bases
TTGTCAGTGACTACTCAGCTGTTGGTGCTGTACTACAGCCGTCACGGAAAAACCAAATTACTTGCTCGCCAAATTGCCCG
GGGAATTGAATCCATTCCCCATTGCGAAGCTGTCCTGCGCACCGTTACAGAATTGAACGCCAGCTCACAACAAGCATCAG
AGCCTATTGTTACTCTGGATGAGTTGCGTAACTGTGACGGGCTTGCTTTGGGAAGCCCAGTTTGGTTTGGTGCAATGGCA
ACGCCACTAAAGCACTTTTGGGATCAAACCTCACCGCTGTGGTTGAATGGTTCTTTGATTGATAAACCAGCCTGTGTTTT
TACTTCATCAAGTAGTATGCACGGGGGTCAAGAAACGACGCTACAGAATATGATGGTCCCACTACTGCATCACGGCATGT
TGATTTTGGGTATTCCTTATTCGGAGCCTGATCTGCACCAAACACAATCGGGTGGCACCCCATATGGCGCAAGTAGTGTT
GGTCACGAAAGCTCACTCACCACAGAAGAAATTCGCTTGGCGCAACAATTAGGAAAGCGCTTGGCACTGGTTGCCAAAAA
GCAAAAGGAGTCGTAG

Upstream 100 bases:

>100_bases
GATGGCAGAAAACCCATCACTTTTTGAACGCCCTGTCGTGGTTGCTAATGGCCAAGCTCGTATTGGTCGCCCACCAGAGC
AAGTATTAGAGATTTTGTAA

Downstream 100 bases:

>100_bases
ATGTCTGATGTCGACATGAGTCCAAAAACACAGCAGTACCGCTATTTGGCATTGTTTGGCAATTTATCGCTGTTACTGTG
GGTTGTACTTTGGCAATTGG

Product: Trp repressor binding protein WrbA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MSVTTQLLVLYYSRHGKTKLLARQIARGIESIPHCEAVLRTVTELNASSQQASEPIVTLDELRNCDGLALGSPVWFGAMA
TPLKHFWDQTSPLWLNGSLIDKPACVFTSSSSMHGGQETTLQNMMVPLLHHGMLILGIPYSEPDLHQTQSGGTPYGASSV
GHESSLTTEEIRLAQQLGKRLALVAKKQKES

Sequences:

>Translated_191_residues
MSVTTQLLVLYYSRHGKTKLLARQIARGIESIPHCEAVLRTVTELNASSQQASEPIVTLDELRNCDGLALGSPVWFGAMA
TPLKHFWDQTSPLWLNGSLIDKPACVFTSSSSMHGGQETTLQNMMVPLLHHGMLILGIPYSEPDLHQTQSGGTPYGASSV
GHESSLTTEEIRLAQQLGKRLALVAKKQKES
>Mature_190_residues
SVTTQLLVLYYSRHGKTKLLARQIARGIESIPHCEAVLRTVTELNASSQQASEPIVTLDELRNCDGLALGSPVWFGAMAT
PLKHFWDQTSPLWLNGSLIDKPACVFTSSSSMHGGQETTLQNMMVPLLHHGMLILGIPYSEPDLHQTQSGGTPYGASSVG
HESSLTTEEIRLAQQLGKRLALVAKKQKES

Specific function: Seems To Enhance The Formation And/Or Stability Of Noncovalent Complexes Between The Trp Repressor Protein And Operator-Bearing DNA. However, Wrba Does Not Specifically Influence The Affinity Or Mode Of Binding Of Trpr To Its Operator. It Seems Possible T

COG id: COG0655

COG function: function code R; Multimeric flavodoxin WrbA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787239, Length=194, Percent_Identity=36.0824742268041, Blast_Score=116, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6319849, Length=197, Percent_Identity=32.994923857868, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6320235, Length=166, Percent_Identity=29.5180722891566, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008254
- InterPro:   IPR010089 [H]

Pfam domain/function: PF00258 Flavodoxin_1 [H]

EC number: NA

Molecular weight: Translated: 20821; Mature: 20690

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00201 FLAVODOXIN ; PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTTQLLVLYYSRHGKTKLLARQIARGIESIPHCEAVLRTVTELNASSQQASEPIVTLD
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHCCCCEEHH
ELRNCDGLALGSPVWFGAMATPLKHFWDQTSPLWLNGSLIDKPACVFTSSSSMHGGQETT
HHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEECCCCCCCCHHHH
LQNMMVPLLHHGMLILGIPYSEPDLHQTQSGGTPYGASSVGHESSLTTEEIRLAQQLGKR
HHHHHHHHHHCCEEEEECCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LALVAKKQKES
HHHHHHHHCCC
>Mature Secondary Structure 
SVTTQLLVLYYSRHGKTKLLARQIARGIESIPHCEAVLRTVTELNASSQQASEPIVTLD
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHCCCCEEHH
ELRNCDGLALGSPVWFGAMATPLKHFWDQTSPLWLNGSLIDKPACVFTSSSSMHGGQETT
HHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEECCCCCCCCHHHH
LQNMMVPLLHHGMLILGIPYSEPDLHQTQSGGTPYGASSVGHESSLTTEEIRLAQQLGKR
HHHHHHHHHHCCEEEEECCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LALVAKKQKES
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA