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The map label for this gene is fadL [H]

Identifier: 37680628

GI number: 37680628

Start: 2479032

End: 2480258

Strand: Direct

Name: fadL [H]

Synonym: VV2444

Alternate gene names: 37680628

Gene position: 2479032-2480258 (Clockwise)

Preceding gene: 37680627

Following gene: 37680629

Centisome position: 73.9

GC content: 44.99

Gene sequence:

>1227_bases
ATGACTCAGAACATGCGTCTGTTTAAAAAGTCTCTCCTAGCAGTGACTGTTGCATTGGCTTCAGGCCAAACAATGGCAGC
AGGTTTCCAACTTAATGCACAATCTGCAACAGGTATCGGCCGCGCATTCGCCGGTGATGCAGTCATTGCAGATAACGCCG
CCGTTATGGCACGTAACCCAGCCGCTATGGCGCTTTTTGATGAAAAAGCCCTATCGCTTGGTTTTGAAAGCATCACTTCA
ATGATTGAAGTGAAGGATGCAAGGTACCAAGGCTTAACAGCTCCAGCGGGTAAAGAATCGAACTATGATGACGCTGGTGA
TACTTCTATTGCGCCAAATATTCACTTTATCATGCCAGTAAACGATAAGTTTGCTTGGGGTGTTAACGCTTATTCAAACT
TTGGTACAAAAACTGAGTTTGATGACAGTTTCGTTGCGCGTGAATACGGCGGCTTGACGGATGTTAAAAGCGCCAACTTT
GGCTTAGCAGGCTCATATCGCCTTAACGAGCAATGGAGCTTCGGTGCTGGTTTAGACATCATCTACGGCCAAGGCACAAT
GAAACGTGAACATGCTCTAATCGGCACTTTAGTCGATGTAGACAAAGCTGACGGCTGGGCTGTTGGTTTCAATGTGGGCA
CTGTATTTGAACTAGATGAAAACAACCGTTTTGGTTTCTCTTACCGCTACAGTCCAGAAATGGAAGCGGAAGATGACAAA
GGCCAAAAGATCACTCTACCACTACCAGATATGGCGGAGTTTTCGGGTTACCATAAAATTACCGACACCAAATTTGCGGT
TCACTACTCTATCCAATACATTGGCTGGGGCACATTTGATAAAATTGAGTTCCGTAACTTAAAAGACAATTCACCAGCAA
TCGGTGCAAGCTACGACAAAGCTTATGAATGGCAAGATGGTTGGCACTACGCTATTGGTGGTACTTACTACCTAAACAAC
GACTGGACGCTACGTGCGGGTTATATGTATGACACCAGTGCACAAGATTCACTAACATCGGTTTCAGTGCCTGACTCAGA
TCGTCAATGGCTATCTACTGGTTTTACTTACCACATTGATACTAAGTCTAACGTGGACTTTGGCTTTACCTACCTGATGG
GTGACGATGTTAAGGTTAATGAATCTACTGCTGGCGTGTCATCACTAACGGCTACTACTCACGCTGACGCTATCTTGTTC
GGCTTACAATATAGCCGTACTTTCTAA

Upstream 100 bases:

>100_bases
GGATTTGTATCTGCTACTCTTACGACTAGGATCAGCCACCACTGAGCAATTGCTCAAAAACAACGCCCATTTAGAGGCGG
CAACAAAAAGGAATAATCAA

Downstream 100 bases:

>100_bases
TAGAAAATTAGAGAAAACCTCTATGCTAAAGGGCTGGTCTACCAGCCCTTTTTCTTTATTTTCCCGTCTATATCTCACTA
TTTCAGAGCACAACTGTTTG

Product: long-chain fatty acid transport protein

Products: NA

Alternate protein names: Outer membrane fadL protein; Outer membrane flp protein [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MTQNMRLFKKSLLAVTVALASGQTMAAGFQLNAQSATGIGRAFAGDAVIADNAAVMARNPAAMALFDEKALSLGFESITS
MIEVKDARYQGLTAPAGKESNYDDAGDTSIAPNIHFIMPVNDKFAWGVNAYSNFGTKTEFDDSFVAREYGGLTDVKSANF
GLAGSYRLNEQWSFGAGLDIIYGQGTMKREHALIGTLVDVDKADGWAVGFNVGTVFELDENNRFGFSYRYSPEMEAEDDK
GQKITLPLPDMAEFSGYHKITDTKFAVHYSIQYIGWGTFDKIEFRNLKDNSPAIGASYDKAYEWQDGWHYAIGGTYYLNN
DWTLRAGYMYDTSAQDSLTSVSVPDSDRQWLSTGFTYHIDTKSNVDFGFTYLMGDDVKVNESTAGVSSLTATTHADAILF
GLQYSRTF

Sequences:

>Translated_408_residues
MTQNMRLFKKSLLAVTVALASGQTMAAGFQLNAQSATGIGRAFAGDAVIADNAAVMARNPAAMALFDEKALSLGFESITS
MIEVKDARYQGLTAPAGKESNYDDAGDTSIAPNIHFIMPVNDKFAWGVNAYSNFGTKTEFDDSFVAREYGGLTDVKSANF
GLAGSYRLNEQWSFGAGLDIIYGQGTMKREHALIGTLVDVDKADGWAVGFNVGTVFELDENNRFGFSYRYSPEMEAEDDK
GQKITLPLPDMAEFSGYHKITDTKFAVHYSIQYIGWGTFDKIEFRNLKDNSPAIGASYDKAYEWQDGWHYAIGGTYYLNN
DWTLRAGYMYDTSAQDSLTSVSVPDSDRQWLSTGFTYHIDTKSNVDFGFTYLMGDDVKVNESTAGVSSLTATTHADAILF
GLQYSRTF
>Mature_407_residues
TQNMRLFKKSLLAVTVALASGQTMAAGFQLNAQSATGIGRAFAGDAVIADNAAVMARNPAAMALFDEKALSLGFESITSM
IEVKDARYQGLTAPAGKESNYDDAGDTSIAPNIHFIMPVNDKFAWGVNAYSNFGTKTEFDDSFVAREYGGLTDVKSANFG
LAGSYRLNEQWSFGAGLDIIYGQGTMKREHALIGTLVDVDKADGWAVGFNVGTVFELDENNRFGFSYRYSPEMEAEDDKG
QKITLPLPDMAEFSGYHKITDTKFAVHYSIQYIGWGTFDKIEFRNLKDNSPAIGASYDKAYEWQDGWHYAIGGTYYLNND
WTLRAGYMYDTSAQDSLTSVSVPDSDRQWLSTGFTYHIDTKSNVDFGFTYLMGDDVKVNESTAGVSSLTATTHADAILFG
LQYSRTF

Specific function: Involved in translocation of long-chain fatty acids across the outer membrane. FadL may form a specific channel [H]

COG id: COG2067

COG function: function code I; Long-chain fatty acid transport protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ompP1/fadL family [H]

Homologues:

Organism=Escherichia coli, GI145693163, Length=458, Percent_Identity=34.4978165938865, Blast_Score=264, Evalue=9e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR005017 [H]

Pfam domain/function: PF03349 Toluene_X [H]

EC number: NA

Molecular weight: Translated: 44843; Mature: 44712

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQNMRLFKKSLLAVTVALASGQTMAAGFQLNAQSATGIGRAFAGDAVIADNAAVMARNP
CCCCHHHHHHHHHEEEEEEECCCEEEEEEEEECCCCCCCCHHHCCCEEEECCCEEEECCC
AAMALFDEKALSLGFESITSMIEVKDARYQGLTAPAGKESNYDDAGDTSIAPNIHFIMPV
CEEEEECHHHHHHCHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
NDKFAWGVNAYSNFGTKTEFDDSFVAREYGGLTDVKSANFGLAGSYRLNEQWSFGAGLDI
CCCEEECCCCHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCEEE
IYGQGTMKREHALIGTLVDVDKADGWAVGFNVGTVFELDENNRFGFSYRYSPEMEAEDDK
EECCCCCCCCCEEEEEEEEECCCCCEEEEEECCEEEEECCCCCEEEEEEECCCCCCCCCC
GQKITLPLPDMAEFSGYHKITDTKFAVHYSIQYIGWGTFDKIEFRNLKDNSPAIGASYDK
CCEEEECCCCHHHHCCCEEECCCEEEEEEEEEEEECCCCCCEEECCCCCCCCCCCCCCCC
AYEWQDGWHYAIGGTYYLNNDWTLRAGYMYDTSAQDSLTSVSVPDSDRQWLSTGFTYHID
CEECCCCEEEEECEEEEECCCEEEEEEEEECCCCCCCEEEEECCCCCHHHHHCCCEEEEE
TKSNVDFGFTYLMGDDVKVNESTAGVSSLTATTHADAILFGLQYSRTF
CCCCCCEEEEEEECCCEEECCCCCCCHHEEECCCCCEEEEEEEECCCC
>Mature Secondary Structure 
TQNMRLFKKSLLAVTVALASGQTMAAGFQLNAQSATGIGRAFAGDAVIADNAAVMARNP
CCCHHHHHHHHHEEEEEEECCCEEEEEEEEECCCCCCCCHHHCCCEEEECCCEEEECCC
AAMALFDEKALSLGFESITSMIEVKDARYQGLTAPAGKESNYDDAGDTSIAPNIHFIMPV
CEEEEECHHHHHHCHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
NDKFAWGVNAYSNFGTKTEFDDSFVAREYGGLTDVKSANFGLAGSYRLNEQWSFGAGLDI
CCCEEECCCCHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCEEE
IYGQGTMKREHALIGTLVDVDKADGWAVGFNVGTVFELDENNRFGFSYRYSPEMEAEDDK
EECCCCCCCCCEEEEEEEEECCCCCEEEEEECCEEEEECCCCCEEEEEEECCCCCCCCCC
GQKITLPLPDMAEFSGYHKITDTKFAVHYSIQYIGWGTFDKIEFRNLKDNSPAIGASYDK
CCEEEECCCCHHHHCCCEEECCCEEEEEEEEEEEECCCCCCEEECCCCCCCCCCCCCCCC
AYEWQDGWHYAIGGTYYLNNDWTLRAGYMYDTSAQDSLTSVSVPDSDRQWLSTGFTYHID
CEECCCCEEEEECEEEEECCCEEEEEEEEECCCCCCCEEEEECCCCCHHHHHCCCEEEEE
TKSNVDFGFTYLMGDDVKVNESTAGVSSLTATTHADAILFGLQYSRTF
CCCCCCEEEEEEECCCEEECCCCCCCHHEEECCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]