Click here to switch to the map view.

The map label for this gene is rstB [H]

Identifier: 37680590

GI number: 37680590

Start: 2435907

End: 2437541

Strand: Direct

Name: rstB [H]

Synonym: VV2406

Alternate gene names: 37680590

Gene position: 2435907-2437541 (Clockwise)

Preceding gene: 37680589

Following gene: 37680591

Centisome position: 72.62

GC content: 48.13

Gene sequence:

>1635_bases
GTGTGCCTCTTCTTGGGAGGTTTCAATATGATTCGCGCATTTGCCATCTTATGGTTGGCGGTGTTTGTACCGACTACTTT
GTTGATCATCCCCAGTGGGGTAAACCCGGTTTTAAAACTCAACGAGCAGTTTTCCGAAGATTTCTATAAGCCGATCTATC
GGGTGAACTTTGAGGTGTTGTCCAACAAACTCTTGCAGCAACCCACGACTCAGTGGCAACAAACGATCGACCACTATGCC
AAAAGCTTTGCCTATCCTGTAAAGCTCCAACCGTTGGCAGACTACCAAGCCGACAACACCATCTATGCTTCACTACAACA
AGGCCAAGTAACGTTTCTTTATGCCGACCCAATGGCGCTCTTACAACGAGTTGGCGACAGTGACCAAGTGCTGTATATCG
CTCTTAACGAATCCACCGAGCATGCAGTGCTCAATCAGGCCAAGGGTACACTTTCATTAGCGATTGAAGATCTGCGTCAA
CTGCCTAAAAGTGAGTGGAAAAACACGCTAGCACAAACCAACGCCAAACTCCCTGTCCACATTAGTTTGACCAACGAAAC
GCAACTTAGCGAGACTGCCAAGCTCGCTTTGTTGAACTCCCCCGACGAGATTGTTAGTTATATCAATGATGAGGGACGCG
TCGAGCTACTTGCCCCCATCGATGATGGCTTGTGGTTACACGTCCAAGATAACTTATCGCAAGCCGTACAACTCAAGTTG
AGCACCACCATCGCGCTGATGTTCTTCCTACTGATTTCGCTTGCTTTGATTTTGTGGGTTTATCCACTTTGGCGTGATTT
AACTCGACTGGTGGCAACCGCCACCGAATTTGGCCAAGGCAAACTGTCACAACGGGCGCGAGCTTCCAAGCTCTCGGTGG
TTTCTCAACTCAGTGACTCCTTCAACAACATGGCCGACAATATCGAGAGTCTCATTGCTCGGCAGCGTGAGCTGACCAAC
GCCGTCGCACACGATTTACGTACGCCATTGTATCGGCTGCGCTTTGCGATTGAGATGCTGGAAGATCCTCACACCAGCGA
CGCGCAAAAAGAGAAATATCAACGCGCACTGCACACAAGCATTGATGATCTCGACCATCTCATCAATCAGAATTTACTGC
TCTCTCGCTACAATCGGATTGCCGATATCACCCATTTTTCACCATGTTGCTTTGCTAGGGAGTTGCTCAATGAAATCGAT
GATTTCAAACTTCAGCATCCCGAACTCGATATCCAGTTTTACTGCTCGCCAGAGTTAAAACAGCACCGCATGTTCATCGA
CAACAAAGGATTGATGCGCGCGGTGAAAAACCTTCTTACCAATGCAAGCCGATTTGCTCAAAGTACCATTATTGTCTCGT
TTAAATACAGTGGCAGCGCATTTCACATTACGGTGGAAGACGATGGCCAAGGTGTGCCCAATGAACACGCAGAACGCATT
TTTGAACCTTTCACTCAGCTTGATAACCAAGCACGCAGTAGCGAAAAAGGACATGGGTTAGGATTGGCGATCGTTAAACA
AATCATGCTTTGGCACAAAGGCAACGCGAAAGTGGTGTCATCGACTTTGGGTGGTGCAGCGTTTGAACTGCAGTGGCCTG
AGCTGCATCCGAATACTGCCGAGTCGGAATTGTGA

Upstream 100 bases:

>100_bases
GCTCCATCGACCGAAGAATTTCTCGCCTGCGCCGCACCCTCAATGATGACCCCAACGAACCAACCTTAATCAAGACCATT
CGCGGCGTTGGTTATCAGCT

Downstream 100 bases:

>100_bases
CCAAAATGGACACAATTCGTCCATAAAACACCAACGATTTATCGATGTGGTGAATGCTAATTTGGAATGGCTTTCAAACG
TCATTCACAAGGAATTAGCA

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MCLFLGGFNMIRAFAILWLAVFVPTTLLIIPSGVNPVLKLNEQFSEDFYKPIYRVNFEVLSNKLLQQPTTQWQQTIDHYA
KSFAYPVKLQPLADYQADNTIYASLQQGQVTFLYADPMALLQRVGDSDQVLYIALNESTEHAVLNQAKGTLSLAIEDLRQ
LPKSEWKNTLAQTNAKLPVHISLTNETQLSETAKLALLNSPDEIVSYINDEGRVELLAPIDDGLWLHVQDNLSQAVQLKL
STTIALMFFLLISLALILWVYPLWRDLTRLVATATEFGQGKLSQRARASKLSVVSQLSDSFNNMADNIESLIARQRELTN
AVAHDLRTPLYRLRFAIEMLEDPHTSDAQKEKYQRALHTSIDDLDHLINQNLLLSRYNRIADITHFSPCCFARELLNEID
DFKLQHPELDIQFYCSPELKQHRMFIDNKGLMRAVKNLLTNASRFAQSTIIVSFKYSGSAFHITVEDDGQGVPNEHAERI
FEPFTQLDNQARSSEKGHGLGLAIVKQIMLWHKGNAKVVSSTLGGAAFELQWPELHPNTAESEL

Sequences:

>Translated_544_residues
MCLFLGGFNMIRAFAILWLAVFVPTTLLIIPSGVNPVLKLNEQFSEDFYKPIYRVNFEVLSNKLLQQPTTQWQQTIDHYA
KSFAYPVKLQPLADYQADNTIYASLQQGQVTFLYADPMALLQRVGDSDQVLYIALNESTEHAVLNQAKGTLSLAIEDLRQ
LPKSEWKNTLAQTNAKLPVHISLTNETQLSETAKLALLNSPDEIVSYINDEGRVELLAPIDDGLWLHVQDNLSQAVQLKL
STTIALMFFLLISLALILWVYPLWRDLTRLVATATEFGQGKLSQRARASKLSVVSQLSDSFNNMADNIESLIARQRELTN
AVAHDLRTPLYRLRFAIEMLEDPHTSDAQKEKYQRALHTSIDDLDHLINQNLLLSRYNRIADITHFSPCCFARELLNEID
DFKLQHPELDIQFYCSPELKQHRMFIDNKGLMRAVKNLLTNASRFAQSTIIVSFKYSGSAFHITVEDDGQGVPNEHAERI
FEPFTQLDNQARSSEKGHGLGLAIVKQIMLWHKGNAKVVSSTLGGAAFELQWPELHPNTAESEL
>Mature_544_residues
MCLFLGGFNMIRAFAILWLAVFVPTTLLIIPSGVNPVLKLNEQFSEDFYKPIYRVNFEVLSNKLLQQPTTQWQQTIDHYA
KSFAYPVKLQPLADYQADNTIYASLQQGQVTFLYADPMALLQRVGDSDQVLYIALNESTEHAVLNQAKGTLSLAIEDLRQ
LPKSEWKNTLAQTNAKLPVHISLTNETQLSETAKLALLNSPDEIVSYINDEGRVELLAPIDDGLWLHVQDNLSQAVQLKL
STTIALMFFLLISLALILWVYPLWRDLTRLVATATEFGQGKLSQRARASKLSVVSQLSDSFNNMADNIESLIARQRELTN
AVAHDLRTPLYRLRFAIEMLEDPHTSDAQKEKYQRALHTSIDDLDHLINQNLLLSRYNRIADITHFSPCCFARELLNEID
DFKLQHPELDIQFYCSPELKQHRMFIDNKGLMRAVKNLLTNASRFAQSTIIVSFKYSGSAFHITVEDDGQGVPNEHAERI
FEPFTQLDNQARSSEKGHGLGLAIVKQIMLWHKGNAKVVSSTLGGAAFELQWPELHPNTAESEL

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=398, Percent_Identity=32.1608040201005, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1790346, Length=266, Percent_Identity=30.8270676691729, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1789808, Length=347, Percent_Identity=28.2420749279539, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786783, Length=234, Percent_Identity=29.0598290598291, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI48994928, Length=227, Percent_Identity=27.7533039647577, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=25.78125, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786600, Length=240, Percent_Identity=28.3333333333333, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1789403, Length=247, Percent_Identity=27.9352226720648, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788549, Length=220, Percent_Identity=29.0909090909091, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786912, Length=243, Percent_Identity=28.3950617283951, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082128, Length=299, Percent_Identity=25.0836120401338, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788279, Length=283, Percent_Identity=26.1484098939929, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61581; Mature: 61581

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCLFLGGFNMIRAFAILWLAVFVPTTLLIIPSGVNPVLKLNEQFSEDFYKPIYRVNFEVL
CEEEECCHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SNKLLQQPTTQWQQTIDHYAKSFAYPVKLQPLADYQADNTIYASLQQGQVTFLYADPMAL
HHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEEEECCCCEEEEEECHHHH
LQRVGDSDQVLYIALNESTEHAVLNQAKGTLSLAIEDLRQLPKSEWKNTLAQTNAKLPVH
HHHCCCCCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEE
ISLTNETQLSETAKLALLNSPDEIVSYINDEGRVELLAPIDDGLWLHVQDNLSQAVQLKL
EEECCCHHHHHHHHEEEECCHHHHHHHHCCCCCEEEEEECCCCEEEEEECCHHHHHHHHH
STTIALMFFLLISLALILWVYPLWRDLTRLVATATEFGQGKLSQRARASKLSVVSQLSDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FNNMADNIESLIARQRELTNAVAHDLRTPLYRLRFAIEMLEDPHTSDAQKEKYQRALHTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
IDDLDHLINQNLLLSRYNRIADITHFSPCCFARELLNEIDDFKLQHPELDIQFYCSPELK
HHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHH
QHRMFIDNKGLMRAVKNLLTNASRFAQSTIIVSFKYSGSAFHITVEDDGQGVPNEHAERI
HHHHHCCCCHHHHHHHHHHHHHHHHHCEEEEEEEEECCCEEEEEECCCCCCCCHHHHHHH
FEPFTQLDNQARSSEKGHGLGLAIVKQIMLWHKGNAKVVSSTLGGAAFELQWPELHPNTA
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEHHCCCCCEEEEECCCCCCCCC
ESEL
CCCC
>Mature Secondary Structure
MCLFLGGFNMIRAFAILWLAVFVPTTLLIIPSGVNPVLKLNEQFSEDFYKPIYRVNFEVL
CEEEECCHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SNKLLQQPTTQWQQTIDHYAKSFAYPVKLQPLADYQADNTIYASLQQGQVTFLYADPMAL
HHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEEEECCCCEEEEEECHHHH
LQRVGDSDQVLYIALNESTEHAVLNQAKGTLSLAIEDLRQLPKSEWKNTLAQTNAKLPVH
HHHCCCCCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEE
ISLTNETQLSETAKLALLNSPDEIVSYINDEGRVELLAPIDDGLWLHVQDNLSQAVQLKL
EEECCCHHHHHHHHEEEECCHHHHHHHHCCCCCEEEEEECCCCEEEEEECCHHHHHHHHH
STTIALMFFLLISLALILWVYPLWRDLTRLVATATEFGQGKLSQRARASKLSVVSQLSDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FNNMADNIESLIARQRELTNAVAHDLRTPLYRLRFAIEMLEDPHTSDAQKEKYQRALHTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
IDDLDHLINQNLLLSRYNRIADITHFSPCCFARELLNEIDDFKLQHPELDIQFYCSPELK
HHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHH
QHRMFIDNKGLMRAVKNLLTNASRFAQSTIIVSFKYSGSAFHITVEDDGQGVPNEHAERI
HHHHHCCCCHHHHHHHHHHHHHHHHHCEEEEEEEEECCCEEEEEECCCCCCCCHHHHHHH
FEPFTQLDNQARSSEKGHGLGLAIVKQIMLWHKGNAKVVSSTLGGAAFELQWPELHPNTA
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEHHCCCCCEEEEECCCCCCCCC
ESEL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]