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The map label for this gene is yciR [C]

Identifier: 37680251

GI number: 37680251

Start: 2070519

End: 2072234

Strand: Direct

Name: yciR [C]

Synonym: VV2067

Alternate gene names: 37680251

Gene position: 2070519-2072234 (Clockwise)

Preceding gene: 37680250

Following gene: 37680252

Centisome position: 61.72

GC content: 43.41

Gene sequence:

>1716_bases
ATGACAGACGACGTATCTATTGCAGAATCAATCCTGCCAGACTTTGAGCACCTTATGGAAAGTCGCTTTATGCACATCTT
TGATGTGTTCAGCGAGGGGCTATTTCATATGGATGAACAAGGCGTGATGTCGTTCTATAACAAACAGTTTTACCAGCAGT
TTGGCATTGAGAGCGGCATCATCGCGTTAGATACTTGGTTCGAATTGGTGCACCCGCTAGATCGCTCCAAACTCTCTGCC
CGAGTTGATGACCATTTAATGTGTGAAGATTTACGTGTTACTAGCGAGTACCGTGTACGCAAACCTAATGGTCACTACGT
CTGGATTGAAGGAACGGCAGTCACACGTAAGACTGACTCCGGTATTTATTTGATCGGTAGCCACAAAGATATTTCTGAGC
GTAAGCTGATGGAAAGTTACATCCATCAAGTGGCTTTCCATGACAATGCATCTGGTATGGCCAATCGCAGTCGCCTTTTG
CTCGACATCGAGGAATCTTTTCAAGCCTCTTCCCTGCCCTACGCCTTGATTTACATTCAGATTGAAGACATCAAATCGTA
TTTGAGCCATTACGGCAGCGAAATCCTCAACCATGTCGTGCAAAGCATGCTTACTGCCGTCAGCCATCTGCCTGGCCAAG
TTGCAAGACTTTATCGAGTCCGAGATGATGATTTCGCCGTGTTGTTAGAAGGTAACTTCACTGAACAACAGCTGCTGAAC
ATCTGTTCGACCATCAAACAACGCTATCACGATACGGTTGTGGAGCAAGGGCAATTGCTGGGCACGGGGATCAGCATGGG
TCTGATTCCTCGCATCGAAAATACCCACGAAGGCGAAGAGCTACTAAGAAAAGCAGCTCGTACTGGGCAATATGCCAGCA
AGAAAAAAGCAAACAAAATTGCGCTCTACAGTGCTCGCACGCAGCAAATCGTAGACCGTTATTTCTTTATTGAGCAAGGA
TTACAAAGTGCAATTGAATCCCAATCGCTGAATGTTAAGTTCCAGCCGATTGTTTGTGCCAAACACCTAGAAGTAAAAAG
CTTTGAAACACTAGTACGTTGGCGCAGCAAAGAGTTTGGTGAAATCTATCCAGATGAATTTATTACTGTTGCGGAAAATA
AGGGTCTTATTATTGACCTTGGTTATTTTGTTTTTCGCAAGGCATGCGAATTTATTCAAAGATACAACCAGGCCAATAAT
AAAAATATTCGAGTCAATGTAAATGTCTCGGTATTACAATTGCTCAATAGCAATTTTCCTCAACGTATTCATGAAATGGC
CAGTGAATATGGCATCTCACCCAACTCTATCGTTTTAGAGCTTACGGAAACCATTATATTAGACAATAACGCCGCAGCAA
TTGAGCAACTGAATCAGCTGTCTAAATTGGGTTTTCACCTTTCATTGGATGATTTTGGTGCGGGTTATAGCTCACTCAAC
TCCTTCTTTGATTTGCCCATGAAACAGATCAAAATCGATAAATCGATGGCTTGGCGCAGCCTAAAAAACCCTGATTTGAC
TGCCTATCTCTCTTTTCTGATCCAACTTTGCCGCAACAATCAGATCGATGTTGTCATCGAAGGGATCGAAGATGCCGAAA
TGTATCAAACGTTCAGGAATATGGGCGTGAGTTACCTTCAAGGCTACTGGTTTTCCAAGCCATTGAGTCTCGCCTCCGCG
AGTCGCTTTACCTTATCAACTATTGATAAATCATAA

Upstream 100 bases:

>100_bases
GTACTATTGGCGCCTTTGGTGATATAAAGATTTGAAACATTCTGAAACATTTAACCGACATCGTACAGCGATCAAGTAAA
AAGAAGTAACCACCATTCAG

Downstream 100 bases:

>100_bases
CTCGCACCACATAGCATTGAGAAAAATGCCTGCCTAGATCGCAACCTACTTCTTTGTCATAAAAGCTTCACCTTTTCTTC
ACCTAATAACACGGGTTGTG

Product: signal transduction protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 571; Mature: 570

Protein sequence:

>571_residues
MTDDVSIAESILPDFEHLMESRFMHIFDVFSEGLFHMDEQGVMSFYNKQFYQQFGIESGIIALDTWFELVHPLDRSKLSA
RVDDHLMCEDLRVTSEYRVRKPNGHYVWIEGTAVTRKTDSGIYLIGSHKDISERKLMESYIHQVAFHDNASGMANRSRLL
LDIEESFQASSLPYALIYIQIEDIKSYLSHYGSEILNHVVQSMLTAVSHLPGQVARLYRVRDDDFAVLLEGNFTEQQLLN
ICSTIKQRYHDTVVEQGQLLGTGISMGLIPRIENTHEGEELLRKAARTGQYASKKKANKIALYSARTQQIVDRYFFIEQG
LQSAIESQSLNVKFQPIVCAKHLEVKSFETLVRWRSKEFGEIYPDEFITVAENKGLIIDLGYFVFRKACEFIQRYNQANN
KNIRVNVNVSVLQLLNSNFPQRIHEMASEYGISPNSIVLELTETIILDNNAAAIEQLNQLSKLGFHLSLDDFGAGYSSLN
SFFDLPMKQIKIDKSMAWRSLKNPDLTAYLSFLIQLCRNNQIDVVIEGIEDAEMYQTFRNMGVSYLQGYWFSKPLSLASA
SRFTLSTIDKS

Sequences:

>Translated_571_residues
MTDDVSIAESILPDFEHLMESRFMHIFDVFSEGLFHMDEQGVMSFYNKQFYQQFGIESGIIALDTWFELVHPLDRSKLSA
RVDDHLMCEDLRVTSEYRVRKPNGHYVWIEGTAVTRKTDSGIYLIGSHKDISERKLMESYIHQVAFHDNASGMANRSRLL
LDIEESFQASSLPYALIYIQIEDIKSYLSHYGSEILNHVVQSMLTAVSHLPGQVARLYRVRDDDFAVLLEGNFTEQQLLN
ICSTIKQRYHDTVVEQGQLLGTGISMGLIPRIENTHEGEELLRKAARTGQYASKKKANKIALYSARTQQIVDRYFFIEQG
LQSAIESQSLNVKFQPIVCAKHLEVKSFETLVRWRSKEFGEIYPDEFITVAENKGLIIDLGYFVFRKACEFIQRYNQANN
KNIRVNVNVSVLQLLNSNFPQRIHEMASEYGISPNSIVLELTETIILDNNAAAIEQLNQLSKLGFHLSLDDFGAGYSSLN
SFFDLPMKQIKIDKSMAWRSLKNPDLTAYLSFLIQLCRNNQIDVVIEGIEDAEMYQTFRNMGVSYLQGYWFSKPLSLASA
SRFTLSTIDKS
>Mature_570_residues
TDDVSIAESILPDFEHLMESRFMHIFDVFSEGLFHMDEQGVMSFYNKQFYQQFGIESGIIALDTWFELVHPLDRSKLSAR
VDDHLMCEDLRVTSEYRVRKPNGHYVWIEGTAVTRKTDSGIYLIGSHKDISERKLMESYIHQVAFHDNASGMANRSRLLL
DIEESFQASSLPYALIYIQIEDIKSYLSHYGSEILNHVVQSMLTAVSHLPGQVARLYRVRDDDFAVLLEGNFTEQQLLNI
CSTIKQRYHDTVVEQGQLLGTGISMGLIPRIENTHEGEELLRKAARTGQYASKKKANKIALYSARTQQIVDRYFFIEQGL
QSAIESQSLNVKFQPIVCAKHLEVKSFETLVRWRSKEFGEIYPDEFITVAENKGLIIDLGYFVFRKACEFIQRYNQANNK
NIRVNVNVSVLQLLNSNFPQRIHEMASEYGISPNSIVLELTETIILDNNAAAIEQLNQLSKLGFHLSLDDFGAGYSSLNS
FFDLPMKQIKIDKSMAWRSLKNPDLTAYLSFLIQLCRNNQIDVVIEGIEDAEMYQTFRNMGVSYLQGYWFSKPLSLASAS
RFTLSTIDKS

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=452, Percent_Identity=27.6548672566372, Blast_Score=169, Evalue=5e-43,
Organism=Escherichia coli, GI87081921, Length=437, Percent_Identity=26.0869565217391, Blast_Score=152, Evalue=7e-38,
Organism=Escherichia coli, GI1787055, Length=251, Percent_Identity=30.6772908366534, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI87081845, Length=271, Percent_Identity=28.7822878228782, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI87081743, Length=237, Percent_Identity=32.4894514767932, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI226510982, Length=435, Percent_Identity=25.9770114942529, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788502, Length=247, Percent_Identity=28.3400809716599, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786507, Length=238, Percent_Identity=27.7310924369748, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790496, Length=254, Percent_Identity=29.1338582677165, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI87082096, Length=387, Percent_Identity=23.5142118863049, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI1788849, Length=405, Percent_Identity=24.4444444444444, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87081980, Length=227, Percent_Identity=29.5154185022026, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 65429; Mature: 65298

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDDVSIAESILPDFEHLMESRFMHIFDVFSEGLFHMDEQGVMSFYNKQFYQQFGIESGI
CCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCE
IALDTWFELVHPLDRSKLSARVDDHLMCEDLRVTSEYRVRKPNGHYVWIEGTAVTRKTDS
EHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHCCCCCCEEECCCCCEEEEECEEEEEECCC
GIYLIGSHKDISERKLMESYIHQVAFHDNASGMANRSRLLLDIEESFQASSLPYALIYIQ
CEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHCCCCCCCEEEEEEE
IEDIKSYLSHYGSEILNHVVQSMLTAVSHLPGQVARLYRVRDDDFAVLLEGNFTEQQLLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCCHHHHHH
ICSTIKQRYHDTVVEQGQLLGTGISMGLIPRIENTHEGEELLRKAARTGQYASKKKANKI
HHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCEE
ALYSARTQQIVDRYFFIEQGLQSAIESQSLNVKFQPIVCAKHLEVKSFETLVRWRSKEFG
EEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHCCHHHHHHHHHHHCCCCC
EIYPDEFITVAENKGLIIDLGYFVFRKACEFIQRYNQANNKNIRVNVNVSVLQLLNSNFP
CCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHCCCH
QRIHEMASEYGISPNSIVLELTETIILDNNAAAIEQLNQLSKLGFHLSLDDFGAGYSSLN
HHHHHHHHHHCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHCCCEEEHHHHCCCHHHHH
SFFDLPMKQIKIDKSMAWRSLKNPDLTAYLSFLIQLCRNNQIDVVIEGIEDAEMYQTFRN
HHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHH
MGVSYLQGYWFSKPLSLASASRFTLSTIDKS
CCHHHHHHHHCCCCHHHHCCCCEEECCCCCC
>Mature Secondary Structure 
TDDVSIAESILPDFEHLMESRFMHIFDVFSEGLFHMDEQGVMSFYNKQFYQQFGIESGI
CCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCE
IALDTWFELVHPLDRSKLSARVDDHLMCEDLRVTSEYRVRKPNGHYVWIEGTAVTRKTDS
EHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHCCCCCCEEECCCCCEEEEECEEEEEECCC
GIYLIGSHKDISERKLMESYIHQVAFHDNASGMANRSRLLLDIEESFQASSLPYALIYIQ
CEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHCCCCCCCEEEEEEE
IEDIKSYLSHYGSEILNHVVQSMLTAVSHLPGQVARLYRVRDDDFAVLLEGNFTEQQLLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCCHHHHHH
ICSTIKQRYHDTVVEQGQLLGTGISMGLIPRIENTHEGEELLRKAARTGQYASKKKANKI
HHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCEE
ALYSARTQQIVDRYFFIEQGLQSAIESQSLNVKFQPIVCAKHLEVKSFETLVRWRSKEFG
EEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHCCHHHHHHHHHHHCCCCC
EIYPDEFITVAENKGLIIDLGYFVFRKACEFIQRYNQANNKNIRVNVNVSVLQLLNSNFP
CCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHCCCH
QRIHEMASEYGISPNSIVLELTETIILDNNAAAIEQLNQLSKLGFHLSLDDFGAGYSSLN
HHHHHHHHHHCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHCCCEEEHHHHCCCHHHHH
SFFDLPMKQIKIDKSMAWRSLKNPDLTAYLSFLIQLCRNNQIDVVIEGIEDAEMYQTFRN
HHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHH
MGVSYLQGYWFSKPLSLASASRFTLSTIDKS
CCHHHHHHHHCCCCHHHHCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]