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The map label for this gene is speA [H]

Identifier: 37680170

GI number: 37680170

Start: 1983205

End: 1985127

Strand: Direct

Name: speA [H]

Synonym: VV1986

Alternate gene names: 37680170

Gene position: 1983205-1985127 (Clockwise)

Preceding gene: 37680168

Following gene: 37680171

Centisome position: 59.12

GC content: 47.74

Gene sequence:

>1923_bases
GTGAGATTAGATGTGGAACAAACATCCAAATTAGACCGCGTTCGCGCCGACTACAACGTGCACTACTGGAGTCAAGGTTT
TTACGGTATTGACGACCAAGGCGAAATGTACGTTTCCCCACGTAGTGATAATGCCCACCAGATTCAGCTAAGCAAAATCG
TTAAGCAGCTAGAAGAGCGTCAGCTCAATGTACCTGTGCTGGTTCGATTTCCGCAAATCCTGCATCAACGTGTGCATTCA
ATCTGTGACGCGTTTAACCAGGCAATTGAAGAATATCAATACCCAAATAAATACCTGTTAGTGTACCCAATCAAGGTAAA
CCAACAGCGTGAAGTGGTAGACGAGATTCTTGCCAGCCAGGCACAACTGGAAACCAAACAGCTAGGCCTAGAGGCAGGCA
GTAAGCCTGAGCTTCTCGCCGTTCTAGCCATGGCTCAGCACGCAAGCTCTGTTATCGTTTGTAACGGTTATAAAGACCGT
GAGTACATCCGTTTGGCACTGATTGGTGAAAAACTTGGTCACAAAGTCTTCATCGTACTTGAGAAAATGTCCGAGCTAGA
CCTTGTGTTAAGAGAAGCAAAAAGTCTTGGTGTGACACCCCGTCTTGGTATCCGTATTCGCCTTGCTTCTCAAGGTGCAG
GTAAATGGCAAGCCAGCGGTGGCGAGAAATCGAAATTTGGTCTCTCTGCATCACAAGTGCTGAATGTGATCAGCCGTTTG
AAGAAAGAAAACCAACTCGATACCTTGCAGCTCGTTCACTTCCACCTAGGTTCGCAAATGGCGAATATTCGCGATGTGCG
TAATGGTGTGAATGAATCAGCACGTTTCTACTGTGAACTGCGTACATTGGGTGCCAACATCACGTACTTCGACGTGGGTG
GCGGCTTAGCGATTGACTATGATGGCACTCGCAGCCAGTCTTCCAACTCGATGAACTACGGCTTGGTGGAGTACGCACGC
AATATCGTCAATACCGTGGGTGACGTGTGTAAAGATTACAAGCAACCAATGCCAGTGATCATTTCTGAGTCTGGTCGTTC
ATTGACAGCACACCACGCAGTGTTGATCTCGAACGTAATTGGTACTGAAACTTACAAACCAGAAACCGTGACAGAGCCAG
AAGAAGACTTCCCTCTTCTACTGAACAACATGTGGCGTAGCTGGTTGAACTTGCACAATGGTACCGATGCTCGTGCACTG
ATCGAAATTTACAACGATACGCAAAGCGACTTGGCGGAAGTGCACTCACAGTTTGCGACCGGGGTATTAACCCTTGAGCA
TCGCGCGTGGGCAGAACAAACATCGCTGCGTATCTACTATGAATTGAACCGTTTGATGAGCACGAAGAACCGCTTCCATC
GCCCAATTCTTGACGAATTGTCAGAGCGTTTAGCGGATAAGTTCTTTGTCAACTTCTCACTGTTCCAATCATTGCCAGAT
TCATGGGGTATTGATCAGGTCTTCCCTGTTCTGCCACTGTCTGGCTTACAAAACGCCGCTGATCGCCGTGCAGTGATGCT
CGACATCACCTGTGACTCAGATGGCGCGATTGACGCCTATGTAGATGGTCAAGGCATCGAAAGCACACTGCCAGTACCTG
CATGGAACGAAGATGAGCCATACTTGATGGGCTTCTTCCTCGTGGGTGCATACCAAGAAATTCTTGGTGACATGCACAAC
CTATTTGGTGACACCCACAGTGTTGTGGTGAACGTGGGCGACCAAGGTGAGATCAACATCGATTTCATCAACGAAGGCGA
CACCGTCGAAGACATGATGCGTTACGTACACATCGATGTAGACCAAATTCGCAAAAATTATCACTCTTTGGTATCGCAGC
GCGTTGACCAAGAGGAACAGCAACAGATTCTAGCAGAGCTTGAACAAGGTCTGTCTGGTTACACCTATTTAGAGGATTTC
TAA

Upstream 100 bases:

>100_bases
CCGTTAATTCGCGCAACACGCGTTGCGTGCCAGGCCATGAGAGGGACTTTCCACTCATGTTTTGTTCTTAATATCCGTTG
CTGTATTTCGGATATACTCT

Downstream 100 bases:

>100_bases
ATGAATGATTTGTTTACTAAAACTGATTATTCACTCTACTCAAACTCGATGAGTTTTGTGCGTCGTCCGTATGTCAAAGA
TCCTGTCGCAGCAGACGCTG

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MRLDVEQTSKLDRVRADYNVHYWSQGFYGIDDQGEMYVSPRSDNAHQIQLSKIVKQLEERQLNVPVLVRFPQILHQRVHS
ICDAFNQAIEEYQYPNKYLLVYPIKVNQQREVVDEILASQAQLETKQLGLEAGSKPELLAVLAMAQHASSVIVCNGYKDR
EYIRLALIGEKLGHKVFIVLEKMSELDLVLREAKSLGVTPRLGIRIRLASQGAGKWQASGGEKSKFGLSASQVLNVISRL
KKENQLDTLQLVHFHLGSQMANIRDVRNGVNESARFYCELRTLGANITYFDVGGGLAIDYDGTRSQSSNSMNYGLVEYAR
NIVNTVGDVCKDYKQPMPVIISESGRSLTAHHAVLISNVIGTETYKPETVTEPEEDFPLLLNNMWRSWLNLHNGTDARAL
IEIYNDTQSDLAEVHSQFATGVLTLEHRAWAEQTSLRIYYELNRLMSTKNRFHRPILDELSERLADKFFVNFSLFQSLPD
SWGIDQVFPVLPLSGLQNAADRRAVMLDITCDSDGAIDAYVDGQGIESTLPVPAWNEDEPYLMGFFLVGAYQEILGDMHN
LFGDTHSVVVNVGDQGEINIDFINEGDTVEDMMRYVHIDVDQIRKNYHSLVSQRVDQEEQQQILAELEQGLSGYTYLEDF

Sequences:

>Translated_640_residues
MRLDVEQTSKLDRVRADYNVHYWSQGFYGIDDQGEMYVSPRSDNAHQIQLSKIVKQLEERQLNVPVLVRFPQILHQRVHS
ICDAFNQAIEEYQYPNKYLLVYPIKVNQQREVVDEILASQAQLETKQLGLEAGSKPELLAVLAMAQHASSVIVCNGYKDR
EYIRLALIGEKLGHKVFIVLEKMSELDLVLREAKSLGVTPRLGIRIRLASQGAGKWQASGGEKSKFGLSASQVLNVISRL
KKENQLDTLQLVHFHLGSQMANIRDVRNGVNESARFYCELRTLGANITYFDVGGGLAIDYDGTRSQSSNSMNYGLVEYAR
NIVNTVGDVCKDYKQPMPVIISESGRSLTAHHAVLISNVIGTETYKPETVTEPEEDFPLLLNNMWRSWLNLHNGTDARAL
IEIYNDTQSDLAEVHSQFATGVLTLEHRAWAEQTSLRIYYELNRLMSTKNRFHRPILDELSERLADKFFVNFSLFQSLPD
SWGIDQVFPVLPLSGLQNAADRRAVMLDITCDSDGAIDAYVDGQGIESTLPVPAWNEDEPYLMGFFLVGAYQEILGDMHN
LFGDTHSVVVNVGDQGEINIDFINEGDTVEDMMRYVHIDVDQIRKNYHSLVSQRVDQEEQQQILAELEQGLSGYTYLEDF
>Mature_640_residues
MRLDVEQTSKLDRVRADYNVHYWSQGFYGIDDQGEMYVSPRSDNAHQIQLSKIVKQLEERQLNVPVLVRFPQILHQRVHS
ICDAFNQAIEEYQYPNKYLLVYPIKVNQQREVVDEILASQAQLETKQLGLEAGSKPELLAVLAMAQHASSVIVCNGYKDR
EYIRLALIGEKLGHKVFIVLEKMSELDLVLREAKSLGVTPRLGIRIRLASQGAGKWQASGGEKSKFGLSASQVLNVISRL
KKENQLDTLQLVHFHLGSQMANIRDVRNGVNESARFYCELRTLGANITYFDVGGGLAIDYDGTRSQSSNSMNYGLVEYAR
NIVNTVGDVCKDYKQPMPVIISESGRSLTAHHAVLISNVIGTETYKPETVTEPEEDFPLLLNNMWRSWLNLHNGTDARAL
IEIYNDTQSDLAEVHSQFATGVLTLEHRAWAEQTSLRIYYELNRLMSTKNRFHRPILDELSERLADKFFVNFSLFQSLPD
SWGIDQVFPVLPLSGLQNAADRRAVMLDITCDSDGAIDAYVDGQGIESTLPVPAWNEDEPYLMGFFLVGAYQEILGDMHN
LFGDTHSVVVNVGDQGEINIDFINEGDTVEDMMRYVHIDVDQIRKNYHSLVSQRVDQEEQQQILAELEQGLSGYTYLEDF

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=639, Percent_Identity=54.3035993740219, Blast_Score=719, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 72494; Mature: 72494

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDVEQTSKLDRVRADYNVHYWSQGFYGIDDQGEMYVSPRSDNAHQIQLSKIVKQLEER
CCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEECCCCCCCCEEHHHHHHHHHHHC
QLNVPVLVRFPQILHQRVHSICDAFNQAIEEYQYPNKYLLVYPIKVNQQREVVDEILASQ
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHH
AQLETKQLGLEAGSKPELLAVLAMAQHASSVIVCNGYKDREYIRLALIGEKLGHKVFIVL
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCHHEEEEEEHHHHCCEEEEEE
EKMSELDLVLREAKSLGVTPRLGIRIRLASQGAGKWQASGGEKSKFGLSASQVLNVISRL
HHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
KKENQLDTLQLVHFHLGSQMANIRDVRNGVNESARFYCELRTLGANITYFDVGGGLAIDY
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEECCCCEEEEC
DGTRSQSSNSMNYGLVEYARNIVNTVGDVCKDYKQPMPVIISESGRSLTAHHAVLISNVI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHHHHHH
GTETYKPETVTEPEEDFPLLLNNMWRSWLNLHNGTDARALIEIYNDTQSDLAEVHSQFAT
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
GVLTLEHRAWAEQTSLRIYYELNRLMSTKNRFHRPILDELSERLADKFFVNFSLFQSLPD
CEEEEEHHHHHHHCCEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC
SWGIDQVFPVLPLSGLQNAADRRAVMLDITCDSDGAIDAYVDGQGIESTLPVPAWNEDEP
CCCCHHHHHHCCCHHCCCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCC
YLMGFFLVGAYQEILGDMHNLFGDTHSVVVNVGDQGEINIDFINEGDTVEDMMRYVHIDV
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCH
DQIRKNYHSLVSQRVDQEEQQQILAELEQGLSGYTYLEDF
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHCCC
>Mature Secondary Structure
MRLDVEQTSKLDRVRADYNVHYWSQGFYGIDDQGEMYVSPRSDNAHQIQLSKIVKQLEER
CCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEECCCCCCCCEEHHHHHHHHHHHC
QLNVPVLVRFPQILHQRVHSICDAFNQAIEEYQYPNKYLLVYPIKVNQQREVVDEILASQ
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHH
AQLETKQLGLEAGSKPELLAVLAMAQHASSVIVCNGYKDREYIRLALIGEKLGHKVFIVL
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCHHEEEEEEHHHHCCEEEEEE
EKMSELDLVLREAKSLGVTPRLGIRIRLASQGAGKWQASGGEKSKFGLSASQVLNVISRL
HHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
KKENQLDTLQLVHFHLGSQMANIRDVRNGVNESARFYCELRTLGANITYFDVGGGLAIDY
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEECCCCEEEEC
DGTRSQSSNSMNYGLVEYARNIVNTVGDVCKDYKQPMPVIISESGRSLTAHHAVLISNVI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHHHHHH
GTETYKPETVTEPEEDFPLLLNNMWRSWLNLHNGTDARALIEIYNDTQSDLAEVHSQFAT
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
GVLTLEHRAWAEQTSLRIYYELNRLMSTKNRFHRPILDELSERLADKFFVNFSLFQSLPD
CEEEEEHHHHHHHCCEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC
SWGIDQVFPVLPLSGLQNAADRRAVMLDITCDSDGAIDAYVDGQGIESTLPVPAWNEDEP
CCCCHHHHHHCCCHHCCCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCC
YLMGFFLVGAYQEILGDMHNLFGDTHSVVVNVGDQGEINIDFINEGDTVEDMMRYVHIDV
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCH
DQIRKNYHSLVSQRVDQEEQQQILAELEQGLSGYTYLEDF
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA