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The map label for this gene is blaI [H]

Identifier: 37522546

GI number: 37522546

Start: 3175775

End: 3176206

Strand: Direct

Name: blaI [H]

Synonym: glr2977

Alternate gene names: 37522546

Gene position: 3175775-3176206 (Clockwise)

Preceding gene: 37522540

Following gene: 37522547

Centisome position: 68.16

GC content: 59.49

Gene sequence:

>432_bases
ATGAATTCATTAGTAGTGGGAGGCACCCTTGTGGCCAGGAAGCGATCGCCGACTTTGACCGAATCAGAGTTGCGCCTGAT
GGAGATTCTCTGGCAGCGGGGCTCAGCCACCGTGGCGGAGGTGGTCGAGGCGTTGCCCAAGCGGTTGTCGCTCGCCTACA
GCACGGTGTTGACCACCCTGCGCATCCTCGAGCAAAAAGGTTACGTCCGCCACACCGAGGAGGGCCGGGCCTTTGTGTAC
TGTCCGCTCGTCGACCGCAACCAGGCGCGCCGCAGCGCGGTGGAATTTGTGCTGAGCCGGTTTTTTAACAATTCGCCGGA
GTTGTTGATGCTCAACATTCTCGAACACGAGGACATCGACGCCGCCGAACTGGAGCGCTTGCGCACGATGATCCAGCAAA
ACGATCCGGGAGAGGACCATGAACAGCGTTGA

Upstream 100 bases:

>100_bases
GCAGTCTATTAGGGATGGGCGCCGCCGCCGATTTGTTTCAACTATTAATTATTTAGTTGACAGGGTCCGGTGGGCTCCGG
TAGGCTGACGGCAGGAATCA

Downstream 100 bases:

>100_bases
TGCGCTATTGCCGCTGGCGCGCGAGGTGGTGGAAGGGTGGCTCAACGGCCTGTGGCAGGGGGCATTGCTTGCGGCGATGG
TTTGGTGTCTGTTGCGCGCC

Product: MarR family transcriptional regulator

Products: NA

Alternate protein names: Beta-lactamase repressor protein; Regulatory protein BlaI [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MNSLVVGGTLVARKRSPTLTESELRLMEILWQRGSATVAEVVEALPKRLSLAYSTVLTTLRILEQKGYVRHTEEGRAFVY
CPLVDRNQARRSAVEFVLSRFFNNSPELLMLNILEHEDIDAAELERLRTMIQQNDPGEDHEQR

Sequences:

>Translated_143_residues
MNSLVVGGTLVARKRSPTLTESELRLMEILWQRGSATVAEVVEALPKRLSLAYSTVLTTLRILEQKGYVRHTEEGRAFVY
CPLVDRNQARRSAVEFVLSRFFNNSPELLMLNILEHEDIDAAELERLRTMIQQNDPGEDHEQR
>Mature_143_residues
MNSLVVGGTLVARKRSPTLTESELRLMEILWQRGSATVAEVVEALPKRLSLAYSTVLTTLRILEQKGYVRHTEEGRAFVY
CPLVDRNQARRSAVEFVLSRFFNNSPELLMLNILEHEDIDAAELERLRTMIQQNDPGEDHEQR

Specific function: Transcriptional repressor that constitutively blocks expression of beta-lactamase. Regulates genes involved in antibiotic resistance. Binds DNA as a dimer [H]

COG id: COG3682

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BlaI transcriptional regulatory family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005650
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03965 Pencillinase_R [H]

EC number: NA

Molecular weight: Translated: 16395; Mature: 16395

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLVVGGTLVARKRSPTLTESELRLMEILWQRGSATVAEVVEALPKRLSLAYSTVLTTL
CCCEEECCEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RILEQKGYVRHTEEGRAFVYCPLVDRNQARRSAVEFVLSRFFNNSPELLMLNILEHEDID
HHHHHCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
AAELERLRTMIQQNDPGEDHEQR
HHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNSLVVGGTLVARKRSPTLTESELRLMEILWQRGSATVAEVVEALPKRLSLAYSTVLTTL
CCCEEECCEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RILEQKGYVRHTEEGRAFVYCPLVDRNQARRSAVEFVLSRFFNNSPELLMLNILEHEDID
HHHHHCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
AAELERLRTMIQQNDPGEDHEQR
HHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3096969; 3305074; 3260234; 3040663; 3498148 [H]