Click here to switch to the map view.

The map label for this gene is infC

Identifier: 37521325

GI number: 37521325

Start: 1861596

End: 1862195

Strand: Reverse

Name: infC

Synonym: gvip244

Alternate gene names: 37521325

Gene position: 1862195-1861596 (Counterclockwise)

Preceding gene: 37521328

Following gene: 37521321

Centisome position: 39.97

GC content: 56.83

Gene sequence:

>600_bases
ATGCTCTGGCTTGCTTTGTTTTTTGGAAGATTTTCTCGCCTGGAGGCTCCTCAAAGATTGGTCATTAAGAAGCGCTCTGA
CCGGGGTCAAGCCAACCTCCCCATGATCAACGAGCGGATCCGCTTTCCGAAGATCCGCGCCATCGACGCCGATGGCACCC
AGTTGGGGATCATGCACCCGCGCGATGCCCTGCGCATTGCCGAGGAACGCAATCTCGATCTGGTGGTAGTCAGCGAAGAC
GCCCAGCCGCCGGTCTGCCGGATCATGGATTATGGTAAATACAAATTCGAGCAAGAGAAACGGGCCAAAGAAGCGCGCAA
GAAACAGCACACCGCCGACGTCAAAGAAGTCAAGATGCGCTATACGATTGGCGAGCACGATTACCAGGTGCGTCTGCGCG
ATACGATCCGCTTTCTCAAAGACGGCGACAAGGTCAAAGCGACCATCATGTTCCGGGGCCGCGAGATCCAGCATGCCAAT
CTGGCCAAAGATTTGCTCATGCAGCTTGCCGCCGACTCCGCCGAGATCGGCGAGGTGCAGCAGGAGCCCTCGGTGGAGGG
GCGCAACATGATTATGATCCTCTCGCCCAAGCGTACGTAA

Upstream 100 bases:

>100_bases
CCTGGATTCCGTTGGTTTGAGCAACTTGACAGGGCAGGTTGGAAAACTTACCCTAATAGTATCAACACCCAAATTTCCAA
TCCAATTGCGGCCTGGGCAA

Downstream 100 bases:

>100_bases
CCACGATGCGTTCGATCCCCGCCCAGTCGCGCACCGTGCGGATACAGCCGTAGCGACTGTCGCGGGCCAATAGTTGCACT
ACCGTCGGGCCCTGACCCGC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MLWLALFFGRFSRLEAPQRLVIKKRSDRGQANLPMINERIRFPKIRAIDADGTQLGIMHPRDALRIAEERNLDLVVVSED
AQPPVCRIMDYGKYKFEQEKRAKEARKKQHTADVKEVKMRYTIGEHDYQVRLRDTIRFLKDGDKVKATIMFRGREIQHAN
LAKDLLMQLAADSAEIGEVQQEPSVEGRNMIMILSPKRT

Sequences:

>Translated_199_residues
MLWLALFFGRFSRLEAPQRLVIKKRSDRGQANLPMINERIRFPKIRAIDADGTQLGIMHPRDALRIAEERNLDLVVVSED
AQPPVCRIMDYGKYKFEQEKRAKEARKKQHTADVKEVKMRYTIGEHDYQVRLRDTIRFLKDGDKVKATIMFRGREIQHAN
LAKDLLMQLAADSAEIGEVQQEPSVEGRNMIMILSPKRT
>Mature_199_residues
MLWLALFFGRFSRLEAPQRLVIKKRSDRGQANLPMINERIRFPKIRAIDADGTQLGIMHPRDALRIAEERNLDLVVVSED
AQPPVCRIMDYGKYKFEQEKRAKEARKKQHTADVKEVKMRYTIGEHDYQVRLRDTIRFLKDGDKVKATIMFRGREIQHAN
LAKDLLMQLAADSAEIGEVQQEPSVEGRNMIMILSPKRT

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=48.780487804878, Blast_Score=141, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_GLOVI (Q7NJS6)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_924702.1
- ProteinModelPortal:   Q7NJS6
- GeneID:   2600158
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.1756
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- ProtClustDB:   PRK00028
- BioCyc:   GVIO251221:GLL1756-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 23131; Mature: 23131

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWLALFFGRFSRLEAPQRLVIKKRSDRGQANLPMINERIRFPKIRAIDADGTQLGIMHP
CCHHHHHHHHHHHCCCCHHEEEEECCCCCCCCCCCHHHHCCCCEEEEECCCCCEEEEECC
RDALRIAEERNLDLVVVSEDAQPPVCRIMDYGKYKFEQEKRAKEARKKQHTADVKEVKMR
HHHHHHHHHCCCEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHEEEE
YTIGEHDYQVRLRDTIRFLKDGDKVKATIMFRGREIQHANLAKDLLMQLAADSAEIGEVQ
EEECCCCEEEEHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHCCCC
QEPSVEGRNMIMILSPKRT
CCCCCCCCCEEEEECCCCC
>Mature Secondary Structure
MLWLALFFGRFSRLEAPQRLVIKKRSDRGQANLPMINERIRFPKIRAIDADGTQLGIMHP
CCHHHHHHHHHHHCCCCHHEEEEECCCCCCCCCCCHHHHCCCCEEEEECCCCCEEEEECC
RDALRIAEERNLDLVVVSEDAQPPVCRIMDYGKYKFEQEKRAKEARKKQHTADVKEVKMR
HHHHHHHHHCCCEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHEEEE
YTIGEHDYQVRLRDTIRFLKDGDKVKATIMFRGREIQHANLAKDLLMQLAADSAEIGEVQ
EEECCCCEEEEHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHCCCC
QEPSVEGRNMIMILSPKRT
CCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292