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The map label for this gene is btuB [H]

Identifier: 37521179

GI number: 37521179

Start: 1726198

End: 1728456

Strand: Direct

Name: btuB [H]

Synonym: glr1610

Alternate gene names: 37521179

Gene position: 1726198-1728456 (Clockwise)

Preceding gene: 37521178

Following gene: 37521183

Centisome position: 37.05

GC content: 63.21

Gene sequence:

>2259_bases
GTGAGCACCGAACGTCACTCCAGAGCGCGCGCCCGTCCGGCTTGGAATTGGCTGCTTTTCGCCATAGCCTACGGTTGGAT
CCCGGCAGTACCCAGCCTCGCTCTACCCACCGTCGCGGACCTGCTGCCGGACATGAGCACCCGGGCCGGCGATCTGCTGG
TCCAGTCCTCCGGTGATGCTTCGCCCGCCGAGCCCACGAGTCCCGGCAACGACAGCGATCTGCTGCCTGCGGTCACCGTC
ACCGCCACGCGCAGAAGCGAGCCCATTCTCGACGTGCCGACGGCGACCACGATTGTCCCTAGCGCCCAGGCTCAAGAGCG
AACCCAGACGGATCTTGCGGATCTGCTGCGCGGCGAGACGGGCGTGTACGTGCGCGCCACCAACCCGAGCGCCGGATCGC
CCGTGATCCGGGGAGCGACCGGCCGGGATGTGCTGTTGTTGGTGGACGGCTTTCGGCTTTCGCCCGCTTTCGCGCGCCCG
AACGTTCAGTACCAGAGCCTGGTCGATCCGTTCTTCATCGATCAAATCGAGATTGTACGCGGACCGGTTTCGACGCTCTA
CGGTTCGGATGCCATGGGCGGGGCCACCAACGTGATCACTCCGAGCTTCAAAGCGGGCGAACCCGCCTTTCGCCTGCACA
CCGACTACAACACCAACCCGGCAGGGAGCAGCACGTACTTTCAGTACCAGGGCGGCAGTGAGCGTGCGTGGGCGATGATG
GGCCTCACTTACCGCAGCTTCGGCGATCTGGCCGTTGGGGCCGCTCCCGACTTGCAGGTGATCTTCCCCAATCCCACGGC
GCGCATCGGCCGCTCGGGCTACGAGTACTACGGCGCCAATTTCAAAGGGGAAGTGCGCCTGGCGGACAACCAGTTTTTGA
CCCTTACCACCCAGTACAGCCGCATCCCGACCGTCCAGCGCCAGGACGGGATCATCCAGGGTTATGGCGAGAACGTCACC
TCTGCCCAGCGCGGCTTTTCGCCCCAGGGGCGCACCTTCTTCCTGGGCGAGTACCGGGCGGTTTTTAATCATTCCTGGCT
AGACGAAGTGCGCGTGCGTCTGGGTTATCAGCAGATCCAGGACGATCGCTTCCAGCGCAATTTTGCCCGGCCCCGGCCGA
GCTTTCCCGACTACGGCAGCGGCACCCCGAGCCCCGACATCACCCTGGAGAGCAACTTCTCGGATCTGATCGGCACCTCG
GCGGTGCTCAAGAGCACTTGGGGCAATAACGTTTTCACCTACGGCGCGGAGGCCTACTTCGACCTGGTGGGCAGCACCCG
ATCGATACGCAACGACACAACCGGTACCATCCCCGACCCGAACGGTTCGCGCTACGTCGACGGCTCGACATTCAACCAGT
ACGGTCTATTTGTGCAGGATGAGATCGACTGGAGTACCCAGTTCAAGACCCTGCTTGGGCTGCGCTATTCGCTAGTGGAT
GTATCCGTTCCCTTCAGTGCCGTGCGCCCCAACAGTTCCGGCTTCGGCCGCCGCTTCGAGGCGCTCACCGCCAATGCCGG
TTTTCTGTATCGTTTTGAGCGGGAGCTGCAGTTTGTCATGAATCTGGGTACGGGCTTTCGCGCTCCGAACATCAACGACC
TGGGCAACGCCGGGGAGCGGCGCGCCAGCGACATCAACCTCCCCAATTCCAGCCTCAACCCCGAGAAGGTTTTCTCCGTC
GACGGCGGTCTGCGCTGGGCAGGCAGTGACTTTAAAGGCGAAGTGATCGGGTTTTGGAGCCGCTACACCGATCGGATCAC
CTCGCAGAGCGTGGGTACCGTGGTCAACTCCGACGGCAGCACCTCTGAGGTTTTCCAGTCGGTCAACCGCGACAACGAGA
CCATCTGGGGAATCGAGTTGGGCGGGCGCTACCGTCTCGGGGATGTCTGGTCGCTCTTTGCCACCGGCACCTTCACCTAC
GCGGAAGCGCCCCTGGTGGGCGAGACGGTGATCCCGCCCTTTAACGGCGTGCTGGGCGTTCGCTTTGAACCGACGGCGGG
AGCCTACATCGAGCCCTACCTACGCTACGCCACCTACCAGGGACGGCTTTCGGAGAATAACCTCACCGATACGCGCATCA
ACCCAAACGGCACCCCCGGCTTCGTCGTTCCCAACCTGCGGGCCGGTTTTCCCCTCAGCGGCGCGACAACGCTGCGGGTG
AACGTCAACAATGTGCTCAACACCAATTACCGCGAGCACGGCACGACCCTGGACGCCCCCGGCTTCGGCGTCAACGTCGG
CATCGACGCGCTGTTTTGA

Upstream 100 bases:

>100_bases
TCCGTTTTGAGCGTTCCCGGACTGCTTCTCGGCTTGCCGGAGACTTTCACGCATATACTCTTTGAGTGATAATTCCCAGG
TCACAGGATCTCGGCATCAG

Downstream 100 bases:

>100_bases
TCTTTGTCGTCGAAAATTTCCAAGGTATAGCTGTCGCCATTTAAGTTAGGACGCAGCCTGTTTGAGAACGGCATCCATTG
CGTTGCGCAAATGCCCGCAA

Product: hypothetical protein

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 752; Mature: 751

Protein sequence:

>752_residues
MSTERHSRARARPAWNWLLFAIAYGWIPAVPSLALPTVADLLPDMSTRAGDLLVQSSGDASPAEPTSPGNDSDLLPAVTV
TATRRSEPILDVPTATTIVPSAQAQERTQTDLADLLRGETGVYVRATNPSAGSPVIRGATGRDVLLLVDGFRLSPAFARP
NVQYQSLVDPFFIDQIEIVRGPVSTLYGSDAMGGATNVITPSFKAGEPAFRLHTDYNTNPAGSSTYFQYQGGSERAWAMM
GLTYRSFGDLAVGAAPDLQVIFPNPTARIGRSGYEYYGANFKGEVRLADNQFLTLTTQYSRIPTVQRQDGIIQGYGENVT
SAQRGFSPQGRTFFLGEYRAVFNHSWLDEVRVRLGYQQIQDDRFQRNFARPRPSFPDYGSGTPSPDITLESNFSDLIGTS
AVLKSTWGNNVFTYGAEAYFDLVGSTRSIRNDTTGTIPDPNGSRYVDGSTFNQYGLFVQDEIDWSTQFKTLLGLRYSLVD
VSVPFSAVRPNSSGFGRRFEALTANAGFLYRFERELQFVMNLGTGFRAPNINDLGNAGERRASDINLPNSSLNPEKVFSV
DGGLRWAGSDFKGEVIGFWSRYTDRITSQSVGTVVNSDGSTSEVFQSVNRDNETIWGIELGGRYRLGDVWSLFATGTFTY
AEAPLVGETVIPPFNGVLGVRFEPTAGAYIEPYLRYATYQGRLSENNLTDTRINPNGTPGFVVPNLRAGFPLSGATTLRV
NVNNVLNTNYREHGTTLDAPGFGVNVGIDALF

Sequences:

>Translated_752_residues
MSTERHSRARARPAWNWLLFAIAYGWIPAVPSLALPTVADLLPDMSTRAGDLLVQSSGDASPAEPTSPGNDSDLLPAVTV
TATRRSEPILDVPTATTIVPSAQAQERTQTDLADLLRGETGVYVRATNPSAGSPVIRGATGRDVLLLVDGFRLSPAFARP
NVQYQSLVDPFFIDQIEIVRGPVSTLYGSDAMGGATNVITPSFKAGEPAFRLHTDYNTNPAGSSTYFQYQGGSERAWAMM
GLTYRSFGDLAVGAAPDLQVIFPNPTARIGRSGYEYYGANFKGEVRLADNQFLTLTTQYSRIPTVQRQDGIIQGYGENVT
SAQRGFSPQGRTFFLGEYRAVFNHSWLDEVRVRLGYQQIQDDRFQRNFARPRPSFPDYGSGTPSPDITLESNFSDLIGTS
AVLKSTWGNNVFTYGAEAYFDLVGSTRSIRNDTTGTIPDPNGSRYVDGSTFNQYGLFVQDEIDWSTQFKTLLGLRYSLVD
VSVPFSAVRPNSSGFGRRFEALTANAGFLYRFERELQFVMNLGTGFRAPNINDLGNAGERRASDINLPNSSLNPEKVFSV
DGGLRWAGSDFKGEVIGFWSRYTDRITSQSVGTVVNSDGSTSEVFQSVNRDNETIWGIELGGRYRLGDVWSLFATGTFTY
AEAPLVGETVIPPFNGVLGVRFEPTAGAYIEPYLRYATYQGRLSENNLTDTRINPNGTPGFVVPNLRAGFPLSGATTLRV
NVNNVLNTNYREHGTTLDAPGFGVNVGIDALF
>Mature_751_residues
STERHSRARARPAWNWLLFAIAYGWIPAVPSLALPTVADLLPDMSTRAGDLLVQSSGDASPAEPTSPGNDSDLLPAVTVT
ATRRSEPILDVPTATTIVPSAQAQERTQTDLADLLRGETGVYVRATNPSAGSPVIRGATGRDVLLLVDGFRLSPAFARPN
VQYQSLVDPFFIDQIEIVRGPVSTLYGSDAMGGATNVITPSFKAGEPAFRLHTDYNTNPAGSSTYFQYQGGSERAWAMMG
LTYRSFGDLAVGAAPDLQVIFPNPTARIGRSGYEYYGANFKGEVRLADNQFLTLTTQYSRIPTVQRQDGIIQGYGENVTS
AQRGFSPQGRTFFLGEYRAVFNHSWLDEVRVRLGYQQIQDDRFQRNFARPRPSFPDYGSGTPSPDITLESNFSDLIGTSA
VLKSTWGNNVFTYGAEAYFDLVGSTRSIRNDTTGTIPDPNGSRYVDGSTFNQYGLFVQDEIDWSTQFKTLLGLRYSLVDV
SVPFSAVRPNSSGFGRRFEALTANAGFLYRFERELQFVMNLGTGFRAPNINDLGNAGERRASDINLPNSSLNPEKVFSVD
GGLRWAGSDFKGEVIGFWSRYTDRITSQSVGTVVNSDGSTSEVFQSVNRDNETIWGIELGGRYRLGDVWSLFATGTFTYA
EAPLVGETVIPPFNGVLGVRFEPTAGAYIEPYLRYATYQGRLSENNLTDTRINPNGTPGFVVPNLRAGFPLSGATTLRVN
VNNVLNTNYREHGTTLDAPGFGVNVGIDALF

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=128, Percent_Identity=32.8125, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1790405, Length=141, Percent_Identity=34.0425531914894, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 82181; Mature: 82050

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTERHSRARARPAWNWLLFAIAYGWIPAVPSLALPTVADLLPDMSTRAGDLLVQSSGDA
CCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCC
SPAEPTSPGNDSDLLPAVTVTATRRSEPILDVPTATTIVPSAQAQERTQTDLADLLRGET
CCCCCCCCCCCCCCCCEEEEEECCCCCCCEECCCCEEEECCCHHHHHHHHHHHHHHCCCC
GVYVRATNPSAGSPVIRGATGRDVLLLVDGFRLSPAFARPNVQYQSLVDPFFIDQIEIVR
CEEEEECCCCCCCCEEECCCCCEEEEEEECCCCCCHHCCCCCCHHHHCCCHHHCHHHHHH
GPVSTLYGSDAMGGATNVITPSFKAGEPAFRLHTDYNTNPAGSSTYFQYQGGSERAWAMM
CCHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCEEEEE
GLTYRSFGDLAVGAAPDLQVIFPNPTARIGRSGYEYYGANFKGEVRLADNQFLTLTTQYS
CEEECCCCCEEECCCCCEEEECCCCHHHHCCCCCEEECCCCCEEEEECCCEEEEEEECHH
RIPTVQRQDGIIQGYGENVTSAQRGFSPQGRTFFLGEYRAVFNHSWLDEVRVRLGYQQIQ
HCCCCCCCCCEEECCCCCCHHHHHCCCCCCCEEEEECHHHHHCCCHHHHHHHHHHHHHHH
DDRFQRNFARPRPSFPDYGSGTPSPDITLESNFSDLIGTSAVLKSTWGNNVFTYGAEAYF
HHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCEEEECCHHHH
DLVGSTRSIRNDTTGTIPDPNGSRYVDGSTFNQYGLFVQDEIDWSTQFKTLLGLRYSLVD
HHHCCCHHHCCCCCCCCCCCCCCEEECCCCCCCCCCEEEECCCCHHHHHHHHCCEEEEEE
VSVPFSAVRPNSSGFGRRFEALTANAGFLYRFERELQFVMNLGTGFRAPNINDLGNAGER
EECCHHEECCCCCCCCCEEEEEECCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
RASDINLPNSSLNPEKVFSVDGGLRWAGSDFKGEVIGFWSRYTDRITSQSVGTVVNSDGS
CCCCCCCCCCCCCHHHEEEECCCEEECCCCCCCCEEEHHHHHHHHHHHHCCCEEECCCCC
TSEVFQSVNRDNETIWGIELGGRYRLGDVWSLFATGTFTYAEAPLVGETVIPPFNGVLGV
HHHHHHHHCCCCCEEEEEEECCEEECCHHHHHHHCCEEEEECCCCCCCCCCCCCCCEEEE
RFEPTAGAYIEPYLRYATYQGRLSENNLTDTRINPNGTPGFVVPNLRAGFPLSGATTLRV
EECCCCCCHHHHHHHHHEECCCCCCCCCCCCEECCCCCCCEEECCCCCCCCCCCCEEEEE
NVNNVLNTNYREHGTTLDAPGFGVNVGIDALF
EECHHHCCCCHHCCCEECCCCCEEECCCEECC
>Mature Secondary Structure 
STERHSRARARPAWNWLLFAIAYGWIPAVPSLALPTVADLLPDMSTRAGDLLVQSSGDA
CCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCC
SPAEPTSPGNDSDLLPAVTVTATRRSEPILDVPTATTIVPSAQAQERTQTDLADLLRGET
CCCCCCCCCCCCCCCCEEEEEECCCCCCCEECCCCEEEECCCHHHHHHHHHHHHHHCCCC
GVYVRATNPSAGSPVIRGATGRDVLLLVDGFRLSPAFARPNVQYQSLVDPFFIDQIEIVR
CEEEEECCCCCCCCEEECCCCCEEEEEEECCCCCCHHCCCCCCHHHHCCCHHHCHHHHHH
GPVSTLYGSDAMGGATNVITPSFKAGEPAFRLHTDYNTNPAGSSTYFQYQGGSERAWAMM
CCHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCEEEEE
GLTYRSFGDLAVGAAPDLQVIFPNPTARIGRSGYEYYGANFKGEVRLADNQFLTLTTQYS
CEEECCCCCEEECCCCCEEEECCCCHHHHCCCCCEEECCCCCEEEEECCCEEEEEEECHH
RIPTVQRQDGIIQGYGENVTSAQRGFSPQGRTFFLGEYRAVFNHSWLDEVRVRLGYQQIQ
HCCCCCCCCCEEECCCCCCHHHHHCCCCCCCEEEEECHHHHHCCCHHHHHHHHHHHHHHH
DDRFQRNFARPRPSFPDYGSGTPSPDITLESNFSDLIGTSAVLKSTWGNNVFTYGAEAYF
HHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCEEEECCHHHH
DLVGSTRSIRNDTTGTIPDPNGSRYVDGSTFNQYGLFVQDEIDWSTQFKTLLGLRYSLVD
HHHCCCHHHCCCCCCCCCCCCCCEEECCCCCCCCCCEEEECCCCHHHHHHHHCCEEEEEE
VSVPFSAVRPNSSGFGRRFEALTANAGFLYRFERELQFVMNLGTGFRAPNINDLGNAGER
EECCHHEECCCCCCCCCEEEEEECCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
RASDINLPNSSLNPEKVFSVDGGLRWAGSDFKGEVIGFWSRYTDRITSQSVGTVVNSDGS
CCCCCCCCCCCCCHHHEEEECCCEEECCCCCCCCEEEHHHHHHHHHHHHCCCEEECCCCC
TSEVFQSVNRDNETIWGIELGGRYRLGDVWSLFATGTFTYAEAPLVGETVIPPFNGVLGV
HHHHHHHHCCCCCEEEEEEECCEEECCHHHHHHHCCEEEEECCCCCCCCCCCCCCCEEEE
RFEPTAGAYIEPYLRYATYQGRLSENNLTDTRINPNGTPGFVVPNLRAGFPLSGATTLRV
EECCCCCCHHHHHHHHHEECCCCCCCCCCCCEECCCCCCCEEECCCCCCCCCCCCEEEEE
NVNNVLNTNYREHGTTLDAPGFGVNVGIDALF
EECHHHCCCCHHCCCEECCCCCEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA