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The map label for this gene is hmp [H]

Identifier: 37521141

GI number: 37521141

Start: 1693681

End: 1694109

Strand: Direct

Name: hmp [H]

Synonym: glr1572

Alternate gene names: 37521141

Gene position: 1693681-1694109 (Clockwise)

Preceding gene: 37521140

Following gene: 37521145

Centisome position: 36.35

GC content: 57.34

Gene sequence:

>429_bases
GTGTTAATGGAGGTAACCGCGATGGCCTTGCAGGTAAAGCTGTTGGAACAGAGTTTTGAAGGCGTCAAACCGAACGCCCA
TGCGTTTGCCGCCAGCTTTTACGACAACCTTTTTTCGGATTTTCCGCAGACCCAAGCGCTGTTTGCCCACAGCGATATGC
AAGCCCAGCAGCAAAAATTGCTCGCCTCGCTGGTTCTGGTGGTCGAAAACCTGCGCCAGCCCCAGGTGCTGAGCACAGCT
TTGCAAGATCTGGGCAACCGCCACGCGGGTTACGGCATCGTTCCTGAGCACTACCCGATGGTGGGCACTTCACTGCTCAA
GACGTTCGAAACTTACCTGGGCGACGCCTGGACCCCCGAGGTCAAACAAGCCTGGGTGGATGCTTACGGTGCCATCACCG
GGCTGATGCTCACCGGGGCCGAAAGCTGA

Upstream 100 bases:

>100_bases
ACGCCCTCACCCACCCCGAATCAGATCCGATTTCGGGTCAACCGGAAGTCAAAAGTTGTGCAGTACAGCTTTCGGCGCTG
CCTTGACGAAGTTATGTCGA

Downstream 100 bases:

>100_bases
GTTGCAAGTACGGTATCTAAAGAATGCGGACGAACGGCTGCTTACGGTAGCGCCGGTAGATATCGAAGTCGCTGTCGAGG
CTTGCGACGGCAGCGATATC

Product: flavohemoprotein

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MLMEVTAMALQVKLLEQSFEGVKPNAHAFAASFYDNLFSDFPQTQALFAHSDMQAQQQKLLASLVLVVENLRQPQVLSTA
LQDLGNRHAGYGIVPEHYPMVGTSLLKTFETYLGDAWTPEVKQAWVDAYGAITGLMLTGAES

Sequences:

>Translated_142_residues
MLMEVTAMALQVKLLEQSFEGVKPNAHAFAASFYDNLFSDFPQTQALFAHSDMQAQQQKLLASLVLVVENLRQPQVLSTA
LQDLGNRHAGYGIVPEHYPMVGTSLLKTFETYLGDAWTPEVKQAWVDAYGAITGLMLTGAES
>Mature_142_residues
MLMEVTAMALQVKLLEQSFEGVKPNAHAFAASFYDNLFSDFPQTQALFAHSDMQAQQQKLLASLVLVVENLRQPQVLSTA
LQDLGNRHAGYGIVPEHYPMVGTSLLKTFETYLGDAWTPEVKQAWVDAYGAITGLMLTGAES

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1017

COG function: function code C; Hemoglobin-like flavoprotein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321673, Length=109, Percent_Identity=33.9449541284404, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 15621; Mature: 15621

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMEVTAMALQVKLLEQSFEGVKPNAHAFAASFYDNLFSDFPQTQALFAHSDMQAQQQKL
CCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LASLVLVVENLRQPQVLSTALQDLGNRHAGYGIVPEHYPMVGTSLLKTFETYLGDAWTPE
HHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHH
VKQAWVDAYGAITGLMLTGAES
HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLMEVTAMALQVKLLEQSFEGVKPNAHAFAASFYDNLFSDFPQTQALFAHSDMQAQQQKL
CCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LASLVLVVENLRQPQVLSTALQDLGNRHAGYGIVPEHYPMVGTSLLKTFETYLGDAWTPE
HHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHH
VKQAWVDAYGAITGLMLTGAES
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14521231; 11481432 [H]