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The map label for this gene is rnhA [H]

Identifier: 37521076

GI number: 37521076

Start: 1622346

End: 1622942

Strand: Direct

Name: rnhA [H]

Synonym: gvip209

Alternate gene names: 37521076

Gene position: 1622346-1622942 (Clockwise)

Preceding gene: 37521075

Following gene: 37521077

Centisome position: 34.82

GC content: 68.34

Gene sequence:

>597_bases
GTGGACGAGGTCGGCCGCGGTGCCCTGGCCGGTTGTGTGGTGGCGGCGGCGGTGGTGTTGCCGCCGGATATACCCCTTGC
GGCCCTCGCCGGGATCACCGATTCGAAGTTGCTCGATCGCCCCCGCCGCGAAGCGCTCCACGAGCGCATCCTGGCCCTGG
CATCGGCGGTGGGCATCGGCAGCGCCTCCGTGGGCGAGATCGACCGGCTCAATATCTTGCGGGCGACCGCCCTTGCCATG
GGCCGCGCCCTGCACCGGGTGGCCCCGGTCGAGCATGTCCTGGTGGACGGGTTGCCGGTGGCCGAACTGGGAATCACCCA
GACCGCCATCGTCGGTGGAGACCGCACCAGCCTCAGTATTGCCGCCGCTTCGATCGTGGCCAAGGTGACCCGCGATCGGT
GGATGGAGCGGCTGGACCGGCGCTTTGCGGGCTTCGGTTGGGCCACCAACGCCGGTTACGGTACCGCCTTTCACCGCGAA
GCGCTGGCTCGATTGGGAGTTACCCCTCTGCACCGGCGCAGCTTCGCCCCGGTGCGCCTGGTGGTCCAAAAGAATTTGTT
CGATGAACCGCCGCCGGGCGGGCATTTCGTTGAATAG

Upstream 100 bases:

>100_bases
AATCCGGAGGAATAACATCAAGCGGCCGTCTCAGACTCCCCTGCCTTCGCTGGAGCGCGAGCGCGCCCTATGGGCGGCGG
GCATCCGCCGTCTGGCGGGG

Downstream 100 bases:

>100_bases
TTAAGCGCGGGTGCATAAAATAAAATGCACCCTGTCGCCAGGAACGACGCGGCTTTGTCTACGCTGGTAGTGAAGCGTCT
CAATCCGGCGGGGAAGCGCT

Product: ribonuclease H

Products: NA

Alternate protein names: RNase HII [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MDEVGRGALAGCVVAAAVVLPPDIPLAALAGITDSKLLDRPRREALHERILALASAVGIGSASVGEIDRLNILRATALAM
GRALHRVAPVEHVLVDGLPVAELGITQTAIVGGDRTSLSIAAASIVAKVTRDRWMERLDRRFAGFGWATNAGYGTAFHRE
ALARLGVTPLHRRSFAPVRLVVQKNLFDEPPPGGHFVE

Sequences:

>Translated_198_residues
MDEVGRGALAGCVVAAAVVLPPDIPLAALAGITDSKLLDRPRREALHERILALASAVGIGSASVGEIDRLNILRATALAM
GRALHRVAPVEHVLVDGLPVAELGITQTAIVGGDRTSLSIAAASIVAKVTRDRWMERLDRRFAGFGWATNAGYGTAFHRE
ALARLGVTPLHRRSFAPVRLVVQKNLFDEPPPGGHFVE
>Mature_198_residues
MDEVGRGALAGCVVAAAVVLPPDIPLAALAGITDSKLLDRPRREALHERILALASAVGIGSASVGEIDRLNILRATALAM
GRALHRVAPVEHVLVDGLPVAELGITQTAIVGGDRTSLSIAAASIVAKVTRDRWMERLDRRFAGFGWATNAGYGTAFHRE
ALARLGVTPLHRRSFAPVRLVVQKNLFDEPPPGGHFVE

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family [H]

Homologues:

Organism=Escherichia coli, GI1786380, Length=182, Percent_Identity=51.6483516483517, Blast_Score=147, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 20985; Mature: 20985

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEVGRGALAGCVVAAAVVLPPDIPLAALAGITDSKLLDRPRREALHERILALASAVGIG
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHCCC
SASVGEIDRLNILRATALAMGRALHRVAPVEHVLVDGLPVAELGITQTAIVGGDRTSLSI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHEEECCCCCHHHH
AAASIVAKVTRDRWMERLDRRFAGFGWATNAGYGTAFHREALARLGVTPLHRRSFAPVRL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCCHHHH
VVQKNLFDEPPPGGHFVE
HHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDEVGRGALAGCVVAAAVVLPPDIPLAALAGITDSKLLDRPRREALHERILALASAVGIG
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHCCC
SASVGEIDRLNILRATALAMGRALHRVAPVEHVLVDGLPVAELGITQTAIVGGDRTSLSI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHEEECCCCCHHHH
AAASIVAKVTRDRWMERLDRRFAGFGWATNAGYGTAFHREALARLGVTPLHRRSFAPVRL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCCHHHH
VVQKNLFDEPPPGGHFVE
HHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA