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The map label for this gene is pbpG [H]

Identifier: 37521060

GI number: 37521060

Start: 1602511

End: 1604703

Strand: Direct

Name: pbpG [H]

Synonym: glr1491

Alternate gene names: 37521060

Gene position: 1602511-1604703 (Clockwise)

Preceding gene: 37521057

Following gene: 37521061

Centisome position: 34.4

GC content: 66.07

Gene sequence:

>2193_bases
GTGTCGATAGTACGCCCTGGCGGTGCGGGCCACAGAAGCGATCCCGCTTCCCCGAAGCGGTGCAGGCGCGCCCCAGGCTG
CAGAAGTATAATCAATAGGCTTTTGCATCACGACCGGGCATTGACTACGGAAACGAATCCTTCCGCCAATGTGCAGCACC
CACGCAAGTCGCCTGTGAACTGGCGCCTGGTGGGTTGGATATTGATGGCCCTGGCACTGTCGGTCGGAGCGCTCGCCACC
GGCGCGCTGGTGGGTCTGGCTTTGAGCTTCCGCAACCTGCCCGAGGTGCAGCAGTTGAAGGCGTACGTGCCCACCGGCGC
CACCCGCATCACCGACATCAACGGCCAACCGATCGCGATTATCCGCAGCGAGTACAACCGCAAGGTGGTCCCCCTGGGAC
AGATTTCCAAGCACCTGCAGCGGGCGGTGCTCGCCATCGAGGACGACCGCTTCTACGAACACCCCGGCATCCGCATCGAC
ACTCTGGCGCGCGCCGCCCTCGCCAACTTTCAGGAGGGCCGCACCGTCCAGGGCGGTTCGACCATCACCCAGCAGCTCAT
CAAGAATTTGTTTTTGACCCCCGAGCGCTCGTTGGAGCGCAAAGTGGCCGAGGCGGTCCTCGCGCTGCGCATCGAGCAGG
CCTTCGGCAAAGACCAGATCCTGGAGATGTACCTCAATCAGGTCTACTGGGGCAACAACCGCTACGGCATCGAGACCGCG
AGCCGCGCCTACTTCAACAAACCCGCCAAGAGCCTCAACCTTGCCGAATCGGCGATGCTCGCCGGTATGCTGCGCGCCCC
CGAAATCTATTCGCCCCAGCGCAACCGCGCAAAGACCGTCGAGCGCCAGCGGGTGGTGATCGCCCGGATGCTGGAGTTGG
GCTGGATCACCCAGGCGGAAGCCGACCAAGCCCGCTCGAGCGCTCTGGTCTTCAAAGGTGGCGACGCCGATTTTATGATC
ACCCGGGCGCCCTACTTCTCCAGTTACGTCGTGCGCGAATTGATCCGCAAGTACGGGCGCGACGCCGTGCTCAAGGGCGG
CCTGCGGGTGCAGACCAGCATCGACCTGAAGATCCAGAAGCTGGCGGAACAGACCGTCGCCCGGGCGGCCAAAAACATCC
GCTACCGCCGGGCGGAGCAGCTGGCCCTGGTGGCGATGGACCCGCGCACCGGCTATATCAAGGCGATGGTGGGGGGCGTC
GATTACCAAAAAAGCCAGTACAACCGCGCTTCCCAGGCTTCGCGCCAACCGGGTTCGACCTTCAAACCCTTCGTCTACTA
CGCCGCGCTTGCCACCGGCCGCTATACCCCCGAAACACCCATCACCGACTCGCCCGCCTGCTTCGGCGGCTACTGCCCCA
AAAACTACGACCTGCGCTACTCCGGCGGGATGTCTTTGCGGCAGGCCATGGCCGTCTCGCGCAACGTTCCGGTCGTCAAG
CTCGCCAACACCATCGGCATGAATCAGGTGATCCTGGCGGCCCGCCGCGCCGGGATCACCGCCCCCCTGCAGCCCAACCT
CGCCACCTCAATCGGCGCCGGCGGCATCTCGCCGCTGGAATTGGCGCGCGGCTTCTCGGCCTTCGCCAACGGCGGTTACC
GCGTCGATGCCACCGCCATCCTCCAGGTCACCGACCAACAGGGCAACATCCTGGAGCAGAACCTGCCCGTGCGCGAGCGC
ACCCTCAAATCCGCACCGGTCAAGATGATCAATTCGATGATGATGAGCGTGGTGAGCGGCGGCACCGGTACGCGGGCGCA
ACTGCCCGACGGCAGGCCGGTGGCGGGCAAGACCGGCACCACCCAGGATTTTCGCGACGCCTGGTTCGTGGGCTACGTGC
CCCAACTGGTGTCGGTCGTCTGGATCGGCAACGACGACTACCGCCGACCGATGGCCCGCTCGACCGCGGGCGGCACCTAC
GTGGCCCCCATCTGGCGCTCGTTTATGGCCTCGGCGCTGCGCGGCCAGCCGGTGCTGCCCTTCCCGGGCTTCGAGCCCAG
CGAGAAACCCGCCGACGCCAAGGGCAAAGGCGCCCAACTTGACGAAGCGGCGGCAGAGGCGAAGCCCAAACCGCGCCGCC
GCCGTCGCCGCCGCCCCGCCCCCGAAACGGACGCTCCCCAGCCACGGGAAGCAGCCCTTCCCCTCAAAGCCGCCGAGCCG
GCCCCGGCGGAGCCCGCTCCAGCCGATCCCTAA

Upstream 100 bases:

>100_bases
GGCACCAGCAAGCTGCCCCCGGCCAGATCGATAAAGACCGTCAACAGCACGAACAACAAAGGTGATGGCTTGGGCACGCG
CGCACGGCTAGAGAGGCCAC

Downstream 100 bases:

>100_bases
CACGGTCTTCAGTCGCCCAGACACCCGTAGGCTGGCCAACAACCGGGTGGTCCACCCCTGCCTGTGACCGACAATCGATG
GGCAAAATCGGTAATATAGA

Product: penicillin-binding protein

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 730; Mature: 729

Protein sequence:

>730_residues
MSIVRPGGAGHRSDPASPKRCRRAPGCRSIINRLLHHDRALTTETNPSANVQHPRKSPVNWRLVGWILMALALSVGALAT
GALVGLALSFRNLPEVQQLKAYVPTGATRITDINGQPIAIIRSEYNRKVVPLGQISKHLQRAVLAIEDDRFYEHPGIRID
TLARAALANFQEGRTVQGGSTITQQLIKNLFLTPERSLERKVAEAVLALRIEQAFGKDQILEMYLNQVYWGNNRYGIETA
SRAYFNKPAKSLNLAESAMLAGMLRAPEIYSPQRNRAKTVERQRVVIARMLELGWITQAEADQARSSALVFKGGDADFMI
TRAPYFSSYVVRELIRKYGRDAVLKGGLRVQTSIDLKIQKLAEQTVARAAKNIRYRRAEQLALVAMDPRTGYIKAMVGGV
DYQKSQYNRASQASRQPGSTFKPFVYYAALATGRYTPETPITDSPACFGGYCPKNYDLRYSGGMSLRQAMAVSRNVPVVK
LANTIGMNQVILAARRAGITAPLQPNLATSIGAGGISPLELARGFSAFANGGYRVDATAILQVTDQQGNILEQNLPVRER
TLKSAPVKMINSMMMSVVSGGTGTRAQLPDGRPVAGKTGTTQDFRDAWFVGYVPQLVSVVWIGNDDYRRPMARSTAGGTY
VAPIWRSFMASALRGQPVLPFPGFEPSEKPADAKGKGAQLDEAAAEAKPKPRRRRRRRPAPETDAPQPREAALPLKAAEP
APAEPAPADP

Sequences:

>Translated_730_residues
MSIVRPGGAGHRSDPASPKRCRRAPGCRSIINRLLHHDRALTTETNPSANVQHPRKSPVNWRLVGWILMALALSVGALAT
GALVGLALSFRNLPEVQQLKAYVPTGATRITDINGQPIAIIRSEYNRKVVPLGQISKHLQRAVLAIEDDRFYEHPGIRID
TLARAALANFQEGRTVQGGSTITQQLIKNLFLTPERSLERKVAEAVLALRIEQAFGKDQILEMYLNQVYWGNNRYGIETA
SRAYFNKPAKSLNLAESAMLAGMLRAPEIYSPQRNRAKTVERQRVVIARMLELGWITQAEADQARSSALVFKGGDADFMI
TRAPYFSSYVVRELIRKYGRDAVLKGGLRVQTSIDLKIQKLAEQTVARAAKNIRYRRAEQLALVAMDPRTGYIKAMVGGV
DYQKSQYNRASQASRQPGSTFKPFVYYAALATGRYTPETPITDSPACFGGYCPKNYDLRYSGGMSLRQAMAVSRNVPVVK
LANTIGMNQVILAARRAGITAPLQPNLATSIGAGGISPLELARGFSAFANGGYRVDATAILQVTDQQGNILEQNLPVRER
TLKSAPVKMINSMMMSVVSGGTGTRAQLPDGRPVAGKTGTTQDFRDAWFVGYVPQLVSVVWIGNDDYRRPMARSTAGGTY
VAPIWRSFMASALRGQPVLPFPGFEPSEKPADAKGKGAQLDEAAAEAKPKPRRRRRRRPAPETDAPQPREAALPLKAAEP
APAEPAPADP
>Mature_729_residues
SIVRPGGAGHRSDPASPKRCRRAPGCRSIINRLLHHDRALTTETNPSANVQHPRKSPVNWRLVGWILMALALSVGALATG
ALVGLALSFRNLPEVQQLKAYVPTGATRITDINGQPIAIIRSEYNRKVVPLGQISKHLQRAVLAIEDDRFYEHPGIRIDT
LARAALANFQEGRTVQGGSTITQQLIKNLFLTPERSLERKVAEAVLALRIEQAFGKDQILEMYLNQVYWGNNRYGIETAS
RAYFNKPAKSLNLAESAMLAGMLRAPEIYSPQRNRAKTVERQRVVIARMLELGWITQAEADQARSSALVFKGGDADFMIT
RAPYFSSYVVRELIRKYGRDAVLKGGLRVQTSIDLKIQKLAEQTVARAAKNIRYRRAEQLALVAMDPRTGYIKAMVGGVD
YQKSQYNRASQASRQPGSTFKPFVYYAALATGRYTPETPITDSPACFGGYCPKNYDLRYSGGMSLRQAMAVSRNVPVVKL
ANTIGMNQVILAARRAGITAPLQPNLATSIGAGGISPLELARGFSAFANGGYRVDATAILQVTDQQGNILEQNLPVRERT
LKSAPVKMINSMMMSVVSGGTGTRAQLPDGRPVAGKTGTTQDFRDAWFVGYVPQLVSVVWIGNDDYRRPMARSTAGGTYV
APIWRSFMASALRGQPVLPFPGFEPSEKPADAKGKGAQLDEAAAEAKPKPRRRRRRRPAPETDAPQPREAALPLKAAEPA
PAEPAPADP

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=520, Percent_Identity=36.7307692307692, Blast_Score=268, Evalue=1e-72,
Organism=Escherichia coli, GI87082258, Length=310, Percent_Identity=39.0322580645161, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1788867, Length=510, Percent_Identity=29.0196078431373, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI1789601, Length=165, Percent_Identity=38.1818181818182, Blast_Score=107, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 79879; Mature: 79748

Theoretical pI: Translated: 10.74; Mature: 10.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVRPGGAGHRSDPASPKRCRRAPGCRSIINRLLHHDRALTTETNPSANVQHPRKSPVN
CCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
WRLVGWILMALALSVGALATGALVGLALSFRNLPEVQQLKAYVPTGATRITDINGQPIAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEECCCCEEEE
IRSEYNRKVVPLGQISKHLQRAVLAIEDDRFYEHPGIRIDTLARAALANFQEGRTVQGGS
EECCCCCEECCHHHHHHHHHHHHHEEECCCEECCCCCCHHHHHHHHHHHHHCCCEECCCH
TITQQLIKNLFLTPERSLERKVAEAVLALRIEQAFGKDQILEMYLNQVYWGNNRYGIETA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHEECCCEECCCHH
SRAYFNKPAKSLNLAESAMLAGMLRAPEIYSPQRNRAKTVERQRVVIARMLELGWITQAE
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
ADQARSSALVFKGGDADFMITRAPYFSSYVVRELIRKYGRDAVLKGGLRVQTSIDLKIQK
HHHHHCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCHHHHH
LAEQTVARAAKNIRYRRAEQLALVAMDPRTGYIKAMVGGVDYQKSQYNRASQASRQPGST
HHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEHHHHCCCCHHHHHHHHHHHHCCCCCCC
FKPFVYYAALATGRYTPETPITDSPACFGGYCPKNYDLRYSGGMSLRQAMAVSRNVPVVK
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCEEE
LANTIGMNQVILAARRAGITAPLQPNLATSIGAGGISPLELARGFSAFANGGYRVDATAI
EHHHCCHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEEE
LQVTDQQGNILEQNLPVRERTLKSAPVKMINSMMMSVVSGGTGTRAQLPDGRPVAGKTGT
EEEECCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
TQDFRDAWFVGYVPQLVSVVWIGNDDYRRPMARSTAGGTYVAPIWRSFMASALRGQPVLP
CHHHHHHHHHHHHHHHHEEEEECCCHHHCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCCC
FPGFEPSEKPADAKGKGAQLDEAAAEAKPKPRRRRRRRPAPETDAPQPREAALPLKAAEP
CCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCCCCCCCCHHHCCCCCCCCC
APAEPAPADP
CCCCCCCCCC
>Mature Secondary Structure 
SIVRPGGAGHRSDPASPKRCRRAPGCRSIINRLLHHDRALTTETNPSANVQHPRKSPVN
CCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
WRLVGWILMALALSVGALATGALVGLALSFRNLPEVQQLKAYVPTGATRITDINGQPIAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEECCCCEEEE
IRSEYNRKVVPLGQISKHLQRAVLAIEDDRFYEHPGIRIDTLARAALANFQEGRTVQGGS
EECCCCCEECCHHHHHHHHHHHHHEEECCCEECCCCCCHHHHHHHHHHHHHCCCEECCCH
TITQQLIKNLFLTPERSLERKVAEAVLALRIEQAFGKDQILEMYLNQVYWGNNRYGIETA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHEECCCEECCCHH
SRAYFNKPAKSLNLAESAMLAGMLRAPEIYSPQRNRAKTVERQRVVIARMLELGWITQAE
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
ADQARSSALVFKGGDADFMITRAPYFSSYVVRELIRKYGRDAVLKGGLRVQTSIDLKIQK
HHHHHCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCHHHHH
LAEQTVARAAKNIRYRRAEQLALVAMDPRTGYIKAMVGGVDYQKSQYNRASQASRQPGST
HHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEHHHHCCCCHHHHHHHHHHHHCCCCCCC
FKPFVYYAALATGRYTPETPITDSPACFGGYCPKNYDLRYSGGMSLRQAMAVSRNVPVVK
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCEEE
LANTIGMNQVILAARRAGITAPLQPNLATSIGAGGISPLELARGFSAFANGGYRVDATAI
EHHHCCHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEEE
LQVTDQQGNILEQNLPVRERTLKSAPVKMINSMMMSVVSGGTGTRAQLPDGRPVAGKTGT
EEEECCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
TQDFRDAWFVGYVPQLVSVVWIGNDDYRRPMARSTAGGTYVAPIWRSFMASALRGQPVLP
CHHHHHHHHHHHHHHHHEEEEECCCHHHCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCCC
FPGFEPSEKPADAKGKGAQLDEAAAEAKPKPRRRRRRRPAPETDAPQPREAALPLKAAEP
CCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCCCCCCCCHHHCCCCCCCCC
APAEPAPADP
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]