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The map label for this gene is pheA [H]

Identifier: 37520093

GI number: 37520093

Start: 562840

End: 563673

Strand: Reverse

Name: pheA [H]

Synonym: gll0524

Alternate gene names: 37520093

Gene position: 563673-562840 (Counterclockwise)

Preceding gene: 37520094

Following gene: 37520091

Centisome position: 12.1

GC content: 66.19

Gene sequence:

>834_bases
ATGATTTTGCGCGTCGCCTTTTTGGGACCGAGCGGCACCTACGCCGAGGAAGCCACCCTGGCCCTGTTGGGGAACGAGTG
CGAGCGGCTTGCCCACCCGAGCATCCAGGGCACATTGCGCGCCGCCGCCGCGGGTGAGGTCGACTGTGCCGTGGTGCCGG
TGGAAAACGCCGTCGAGGGCACGGTGAGTGCCACCCTCGACACCCTCTGGCTCTATCCGCAACTGCGGGTGCGCCGGGCG
CTGGTGCTGCCGGTGCGCCACTGCCTCATCGGCCCTGTGCAACACCTCACCGATATCCAGGCGGTCTACTCCCACCCCCA
GGCCCTTGCCCAGTGCCAGGGATGGCTCGAAGAACATCTCGGAGCGGTTGAGCGCATCCCCACCGCTTCGACCAGCGAGG
CGCTGCGCCACATCGGAGCGCACACCGCCGCCATCGCCTCCGAGCGCGCCGCCCGGCTGCACGGGCTCAGGGTCATCTTC
CGGGCGATCAACGACCACCCCGACAACTGCACCCGCTTCTGGCTGGTGAGCGAAAAGCCGCTGACAGAAACGCTCCCCCC
GCCGGGCGGCTGCACCTCGATCGCCTTTGCCCTGCGCCGCAACCAGCCGGGGGTGCTCCACGAGGTACTCTCGATCTTCG
CGCGCCACCGCATCAACCTGGCCAAAATCGAATCGCGGCCGACCAAGAAGGTGATCGGCGAATACTTGTTCTTTGCAGAT
CTCGAAGGCGGAGTCGAGGCTGAACCGGTGAACACAGCCCTTCGGCAGGTGGCCGCAGTGGTGGCCGAACTCAATATCTT
AGGAAGTTACGCAGTCGAGCAGAGCGGCGGTTGA

Upstream 100 bases:

>100_bases
GTTCTACTTCAATGCCATCCAGAATCCGCTGCTCGCGCGCATGGCCCCGGAGCTGTTCAGCGGCACCGGGTTACCGAGCG
AGCGGCAGTAAGATGACTTC

Downstream 100 bases:

>100_bases
ATCGGCTCAGGCCAGACGCATCTTCAGGTACTCGGCCACATCGCTCTCGAGGCGGCGGCGGTAGACCGCATAAAGATCAC
ACACCAGGCGCTCATCGAGG

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MILRVAFLGPSGTYAEEATLALLGNECERLAHPSIQGTLRAAAAGEVDCAVVPVENAVEGTVSATLDTLWLYPQLRVRRA
LVLPVRHCLIGPVQHLTDIQAVYSHPQALAQCQGWLEEHLGAVERIPTASTSEALRHIGAHTAAIASERAARLHGLRVIF
RAINDHPDNCTRFWLVSEKPLTETLPPPGGCTSIAFALRRNQPGVLHEVLSIFARHRINLAKIESRPTKKVIGEYLFFAD
LEGGVEAEPVNTALRQVAAVVAELNILGSYAVEQSGG

Sequences:

>Translated_277_residues
MILRVAFLGPSGTYAEEATLALLGNECERLAHPSIQGTLRAAAAGEVDCAVVPVENAVEGTVSATLDTLWLYPQLRVRRA
LVLPVRHCLIGPVQHLTDIQAVYSHPQALAQCQGWLEEHLGAVERIPTASTSEALRHIGAHTAAIASERAARLHGLRVIF
RAINDHPDNCTRFWLVSEKPLTETLPPPGGCTSIAFALRRNQPGVLHEVLSIFARHRINLAKIESRPTKKVIGEYLFFAD
LEGGVEAEPVNTALRQVAAVVAELNILGSYAVEQSGG
>Mature_277_residues
MILRVAFLGPSGTYAEEATLALLGNECERLAHPSIQGTLRAAAAGEVDCAVVPVENAVEGTVSATLDTLWLYPQLRVRRA
LVLPVRHCLIGPVQHLTDIQAVYSHPQALAQCQGWLEEHLGAVERIPTASTSEALRHIGAHTAAIASERAARLHGLRVIF
RAINDHPDNCTRFWLVSEKPLTETLPPPGGCTSIAFALRRNQPGVLHEVLSIFARHRINLAKIESRPTKKVIGEYLFFAD
LEGGVEAEPVNTALRQVAAVVAELNILGSYAVEQSGG

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=284, Percent_Identity=28.5211267605634, Blast_Score=119, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6324013, Length=287, Percent_Identity=31.3588850174216, Blast_Score=99, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 29929; Mature: 29929

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILRVAFLGPSGTYAEEATLALLGNECERLAHPSIQGTLRAAAAGEVDCAVVPVENAVEG
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCHHHH
TVSATLDTLWLYPQLRVRRALVLPVRHCLIGPVQHLTDIQAVYSHPQALAQCQGWLEEHL
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
GAVERIPTASTSEALRHIGAHTAAIASERAARLHGLRVIFRAINDHPDNCTRFWLVSEKP
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
LTETLPPPGGCTSIAFALRRNQPGVLHEVLSIFARHRINLAKIESRPTKKVIGEYLFFAD
CHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHC
LEGGVEAEPVNTALRQVAAVVAELNILGSYAVEQSGG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MILRVAFLGPSGTYAEEATLALLGNECERLAHPSIQGTLRAAAAGEVDCAVVPVENAVEG
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCHHHH
TVSATLDTLWLYPQLRVRRALVLPVRHCLIGPVQHLTDIQAVYSHPQALAQCQGWLEEHL
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
GAVERIPTASTSEALRHIGAHTAAIASERAARLHGLRVIFRAINDHPDNCTRFWLVSEKP
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
LTETLPPPGGCTSIAFALRRNQPGVLHEVLSIFARHRINLAKIESRPTKKVIGEYLFFAD
CHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHC
LEGGVEAEPVNTALRQVAAVVAELNILGSYAVEQSGG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]