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The map label for this gene is actP1 [H]

Identifier: 34498203

GI number: 34498203

Start: 2983300

End: 2985465

Strand: Reverse

Name: actP1 [H]

Synonym: CV_2748

Alternate gene names: 34498203

Gene position: 2985465-2983300 (Counterclockwise)

Preceding gene: 34498204

Following gene: 34498200

Centisome position: 62.84

GC content: 71.01

Gene sequence:

>2166_bases
CTGCCCATGCTGGGCGTGCTGCTGCTCGACGCCGCTCGGGCCTTGAGGCGGCGGCAGATCGGCGTGGATGTGCTGGCCGT
GCTGTCCATCGCGGTGGCCATCGCGCTGGACGAGCAGGCGACCGCGGCCGTCATCGCCGCGATGGCCGCGACAGGGCGTT
TGCTTGACGCTTTCGCGGCGGGCAAGGCGGCGCGGGAAATGGCGGCCTTGCTGCAGCGCGCGCCGCGCCTGGCCCACCGG
CTGGACGGCGAGGCGCTGAGCACGGTGGCGATAGAGGACATCCGCCCCGGAGACGCGCTGCTGGTCATGCAGGGGGAGAT
GGTGCCGGTCGACGGGCCGCTGGACAGCGGCGAGGCGGCGCTGGACGAATCGCCGTTGACCGGCGAGTCCCTGCCGGTGA
GGATGGTGGCCGGCGGATGGCTGCGCAGCGGCGCCATCAACGCCGGCGAGACGCTGCGCATGATCGCGGCCCGCCGGGCT
GAGGACAGCACTTTCAACGGCATCGTCAAGCTGGTGGGGCAAGCCGCCTCCAGCAAGGCGCCGGCGTCGCGCCTGGCCGA
CCGTTACGCCTTGGGATTCACTCCCGCGGCCTTGGCGCTCGCGGCGCTGGCCTGGTGGGCGAGCGGCGATCCGACGCGCG
GCCTGGCGGTGCTGGTGGTGGCCACGCCTTGCCCCTTGCTGCTGGCGGTGCCGGTCGCCTTGATGTCGGGCATTTCCAAT
TGCGCAGGGCGCGGCGTGCTGGTCAAAGGCGGCCATGCGCTGGAGGCGCTGGCCGCGGCGGATGTGCTGTTCTTCGACAA
GACCGGCACGCTGACCGGCGGCCAGGCGGCGCTGACCGACGTCCGCGCCTATGGCGCGCGCGAAGCCGGCGCCTTGCTGC
GCTTTGCCGCCGCGCTGGACCAGATGTCCTGCCATGTCTTGGCCGCGGCCATTTTGAGAGCGGCGCATGAGCGCGGCAGC
GGTCCGCTGCCCTTGCCGCAACAGGTCGAGGAGCAGCCCGGCGCCGGGATCCGCGGCGTGGTGGAGGGGCGGCGCGTGGC
GATCGGCACGGCGCAATATGTCTTGCTCCACGCGGCGGCGGAGCCGTGGCTGCTCGAGGAGGAAAGGCGGATGGCCACGG
AGGGCGCTTCCGCGGTCTTCGTCGCCGTGGATGGACGGCTGGAGGGCGTGCTGGAACTGTCCGACCAGCTGCGGCTGGAA
ACGCCGCGGGCTTTGAGGCTGTTGCGCCGCGCCGGCGTGAGGCGGATGGTGATGCTGACCGGGGACCGGCGCGAGGTGGC
CGAGTCCATAGGCGGCGGCATAGGCGTGGACGAAGTGCATGCGGAGCTGTCGCCGGCCGACAAGCTGGAACGCGTCGTCC
AGGCGTCCCGCGAGCGGCAGCGCAGCGTGATGGTGGGAGACGGCGTCAACGATGCGCCGGCCTTGGCCGCCGCCGGAGTC
GGCGTGGCGATGGGCGCCCGCGGTTCGGCCGCCGCGGCGGAAAGCGCCGACATCGTGCTGTTGGCGGATCGACTGGACAA
ATTGGCGGAGGCGAAGATGGTGGCCGTCGCCGCGCTGCGGCTGGCCGCGCAAAGTGCCGCCTTGGGCATGGGCCTGTCTC
TGCTGGCCATGCTGTGCGCGGCGGCCGGTTATTTGCCGCCGCTGGAGGGGGCCTTGCTGCAGGAGGCGATAGACGTGGCG
GCCATCGCGAACGCCTTGCGCGCGCTGGGCGTCCGCCCCTTGCGGGGGCAGGGCAAGACTTTGCCGGAGGCGAAGCTGAG
CGCCTTGCGCGAAGAACACAGGCTGCTCGAGCCCTTGTTGGCCAAGCTGTCGGATCTGGCCAGATCGCTGCCGTCCATGG
CGGCCGAATCCAGGCTGGGCGCGATGGATGAGTTGGACGCTTGGCTGCGGCTGGAACTGTTGCCGCATGAAGAGGCCGAT
GAGCGCGCGCTGTATCCCGCAGTCTCGCCGCTACTGGGCGGCGATGACCCCTTGGCCGCGCTGAGCCGCAGCCACCAAGA
AATCTTCCGCGGCATCCACAGGCTGGCGCGTTTGTTCGCCCAGCACAGGGACGCGCCGTCGGAGCCGGGCATCCAGGACA
TCCAGCAGGCGCTTTACGGCCTGGAGGCGGTGCTCAGACTGCATTTCGCCCAGGAGGACGAGCTGTTCAACAGCCTGAGC
GCTTGA

Upstream 100 bases:

>100_bases
GGCGCTGTTGGCCATGCCCGCCGCGGCCCTGCTGTTTGCGCTGATCCGCCAGACATGGGGCGGCGGGGAAGGCGCGTCGC
TGTTGCTGTTGTTATCCTCG

Downstream 100 bases:

>100_bases
ACCCGCGCCGGGCGGACTGGTCCGCCGCGGCGAGGCGCATGGCCGCCGGGCTCAGTCTATCTGCAGCGGGGCGAAGGACT
TGACCAGATCGTCGATGGCC

Product: cation transport P-type ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 721; Mature: 720

Protein sequence:

>721_residues
MPMLGVLLLDAARALRRRQIGVDVLAVLSIAVAIALDEQATAAVIAAMAATGRLLDAFAAGKAAREMAALLQRAPRLAHR
LDGEALSTVAIEDIRPGDALLVMQGEMVPVDGPLDSGEAALDESPLTGESLPVRMVAGGWLRSGAINAGETLRMIAARRA
EDSTFNGIVKLVGQAASSKAPASRLADRYALGFTPAALALAALAWWASGDPTRGLAVLVVATPCPLLLAVPVALMSGISN
CAGRGVLVKGGHALEALAAADVLFFDKTGTLTGGQAALTDVRAYGAREAGALLRFAAALDQMSCHVLAAAILRAAHERGS
GPLPLPQQVEEQPGAGIRGVVEGRRVAIGTAQYVLLHAAAEPWLLEEERRMATEGASAVFVAVDGRLEGVLELSDQLRLE
TPRALRLLRRAGVRRMVMLTGDRREVAESIGGGIGVDEVHAELSPADKLERVVQASRERQRSVMVGDGVNDAPALAAAGV
GVAMGARGSAAAAESADIVLLADRLDKLAEAKMVAVAALRLAAQSAALGMGLSLLAMLCAAAGYLPPLEGALLQEAIDVA
AIANALRALGVRPLRGQGKTLPEAKLSALREEHRLLEPLLAKLSDLARSLPSMAAESRLGAMDELDAWLRLELLPHEEAD
ERALYPAVSPLLGGDDPLAALSRSHQEIFRGIHRLARLFAQHRDAPSEPGIQDIQQALYGLEAVLRLHFAQEDELFNSLS
A

Sequences:

>Translated_721_residues
MPMLGVLLLDAARALRRRQIGVDVLAVLSIAVAIALDEQATAAVIAAMAATGRLLDAFAAGKAAREMAALLQRAPRLAHR
LDGEALSTVAIEDIRPGDALLVMQGEMVPVDGPLDSGEAALDESPLTGESLPVRMVAGGWLRSGAINAGETLRMIAARRA
EDSTFNGIVKLVGQAASSKAPASRLADRYALGFTPAALALAALAWWASGDPTRGLAVLVVATPCPLLLAVPVALMSGISN
CAGRGVLVKGGHALEALAAADVLFFDKTGTLTGGQAALTDVRAYGAREAGALLRFAAALDQMSCHVLAAAILRAAHERGS
GPLPLPQQVEEQPGAGIRGVVEGRRVAIGTAQYVLLHAAAEPWLLEEERRMATEGASAVFVAVDGRLEGVLELSDQLRLE
TPRALRLLRRAGVRRMVMLTGDRREVAESIGGGIGVDEVHAELSPADKLERVVQASRERQRSVMVGDGVNDAPALAAAGV
GVAMGARGSAAAAESADIVLLADRLDKLAEAKMVAVAALRLAAQSAALGMGLSLLAMLCAAAGYLPPLEGALLQEAIDVA
AIANALRALGVRPLRGQGKTLPEAKLSALREEHRLLEPLLAKLSDLARSLPSMAAESRLGAMDELDAWLRLELLPHEEAD
ERALYPAVSPLLGGDDPLAALSRSHQEIFRGIHRLARLFAQHRDAPSEPGIQDIQQALYGLEAVLRLHFAQEDELFNSLS
A
>Mature_720_residues
PMLGVLLLDAARALRRRQIGVDVLAVLSIAVAIALDEQATAAVIAAMAATGRLLDAFAAGKAAREMAALLQRAPRLAHRL
DGEALSTVAIEDIRPGDALLVMQGEMVPVDGPLDSGEAALDESPLTGESLPVRMVAGGWLRSGAINAGETLRMIAARRAE
DSTFNGIVKLVGQAASSKAPASRLADRYALGFTPAALALAALAWWASGDPTRGLAVLVVATPCPLLLAVPVALMSGISNC
AGRGVLVKGGHALEALAAADVLFFDKTGTLTGGQAALTDVRAYGAREAGALLRFAAALDQMSCHVLAAAILRAAHERGSG
PLPLPQQVEEQPGAGIRGVVEGRRVAIGTAQYVLLHAAAEPWLLEEERRMATEGASAVFVAVDGRLEGVLELSDQLRLET
PRALRLLRRAGVRRMVMLTGDRREVAESIGGGIGVDEVHAELSPADKLERVVQASRERQRSVMVGDGVNDAPALAAAGVG
VAMGARGSAAAAESADIVLLADRLDKLAEAKMVAVAALRLAAQSAALGMGLSLLAMLCAAAGYLPPLEGALLQEAIDVAA
IANALRALGVRPLRGQGKTLPEAKLSALREEHRLLEPLLAKLSDLARSLPSMAAESRLGAMDELDAWLRLELLPHEEADE
RALYPAVSPLLGGDDPLAALSRSHQEIFRGIHRLARLFAQHRDAPSEPGIQDIQQALYGLEAVLRLHFAQEDELFNSLSA

Specific function: Involved in copper transport [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HMA domains [H]

Homologues:

Organism=Homo sapiens, GI115529486, Length=656, Percent_Identity=27.8963414634146, Blast_Score=215, Evalue=1e-55,
Organism=Homo sapiens, GI55743071, Length=637, Percent_Identity=28.7284144427002, Blast_Score=208, Evalue=1e-53,
Organism=Homo sapiens, GI55743073, Length=501, Percent_Identity=29.5409181636727, Blast_Score=180, Evalue=4e-45,
Organism=Escherichia coli, GI1786691, Length=550, Percent_Identity=33.8181818181818, Blast_Score=224, Evalue=2e-59,
Organism=Escherichia coli, GI1789879, Length=551, Percent_Identity=33.9382940108893, Blast_Score=209, Evalue=7e-55,
Organism=Escherichia coli, GI1786914, Length=470, Percent_Identity=31.4893617021277, Blast_Score=123, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17556548, Length=558, Percent_Identity=28.8530465949821, Blast_Score=174, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6320475, Length=549, Percent_Identity=28.0510018214936, Blast_Score=187, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6319772, Length=602, Percent_Identity=25.9136212624585, Blast_Score=155, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6325221, Length=563, Percent_Identity=26.2877442273535, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6321430, Length=528, Percent_Identity=26.7045454545455, Blast_Score=88, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6321271, Length=256, Percent_Identity=27.34375, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221329854, Length=400, Percent_Identity=29.75, Blast_Score=135, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24668696, Length=150, Percent_Identity=30.6666666666667, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24668708, Length=150, Percent_Identity=30.6666666666667, Blast_Score=68, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281366617, Length=150, Percent_Identity=30.6666666666667, Blast_Score=68, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24668704, Length=150, Percent_Identity=30.6666666666667, Blast_Score=68, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161085803, Length=150, Percent_Identity=30.6666666666667, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR000695
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR006122
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: =3.6.3.4 [H]

Molecular weight: Translated: 75351; Mature: 75220

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS00154 ATPASE_E1_E2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMLGVLLLDAARALRRRQIGVDVLAVLSIAVAIALDEQATAAVIAAMAATGRLLDAFAA
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GKAAREMAALLQRAPRLAHRLDGEALSTVAIEDIRPGDALLVMQGEMVPVDGPLDSGEAA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCCC
LDESPLTGESLPVRMVAGGWLRSGAINAGETLRMIAARRAEDSTFNGIVKLVGQAASSKA
CCCCCCCCCCCCEEEEECCHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
PASRLADRYALGFTPAALALAALAWWASGDPTRGLAVLVVATPCPLLLAVPVALMSGISN
CHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
CAGRGVLVKGGHALEALAAADVLFFDKTGTLTGGQAALTDVRAYGAREAGALLRFAAALD
HCCCCEEEECCHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
QMSCHVLAAAILRAAHERGSGPLPLPQQVEEQPGAGIRGVVEGRRVAIGTAQYVLLHAAA
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCHHHCCCEEEECHHHHHHHHHCC
EPWLLEEERRMATEGASAVFVAVDGRLEGVLELSDQLRLETPRALRLLRRAGVRRMVMLT
CCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEE
GDRREVAESIGGGIGVDEVHAELSPADKLERVVQASRERQRSVMVGDGVNDAPALAAAGV
CCHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHCC
GVAMGARGSAAAAESADIVLLADRLDKLAEAKMVAVAALRLAAQSAALGMGLSLLAMLCA
CHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AAGYLPPLEGALLQEAIDVAAIANALRALGVRPLRGQGKTLPEAKLSALREEHRLLEPLL
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AKLSDLARSLPSMAAESRLGAMDELDAWLRLELLPHEEADERALYPAVSPLLGGDDPLAA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEECCCCCCCCCHHHHHHHHHCCCCCHHHH
LSRSHQEIFRGIHRLARLFAQHRDAPSEPGIQDIQQALYGLEAVLRLHFAQEDELFNSLS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
A
C
>Mature Secondary Structure 
PMLGVLLLDAARALRRRQIGVDVLAVLSIAVAIALDEQATAAVIAAMAATGRLLDAFAA
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GKAAREMAALLQRAPRLAHRLDGEALSTVAIEDIRPGDALLVMQGEMVPVDGPLDSGEAA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCCC
LDESPLTGESLPVRMVAGGWLRSGAINAGETLRMIAARRAEDSTFNGIVKLVGQAASSKA
CCCCCCCCCCCCEEEEECCHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
PASRLADRYALGFTPAALALAALAWWASGDPTRGLAVLVVATPCPLLLAVPVALMSGISN
CHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
CAGRGVLVKGGHALEALAAADVLFFDKTGTLTGGQAALTDVRAYGAREAGALLRFAAALD
HCCCCEEEECCHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
QMSCHVLAAAILRAAHERGSGPLPLPQQVEEQPGAGIRGVVEGRRVAIGTAQYVLLHAAA
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCHHHCCCEEEECHHHHHHHHHCC
EPWLLEEERRMATEGASAVFVAVDGRLEGVLELSDQLRLETPRALRLLRRAGVRRMVMLT
CCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEE
GDRREVAESIGGGIGVDEVHAELSPADKLERVVQASRERQRSVMVGDGVNDAPALAAAGV
CCHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHCC
GVAMGARGSAAAAESADIVLLADRLDKLAEAKMVAVAALRLAAQSAALGMGLSLLAMLCA
CHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AAGYLPPLEGALLQEAIDVAAIANALRALGVRPLRGQGKTLPEAKLSALREEHRLLEPLL
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AKLSDLARSLPSMAAESRLGAMDELDAWLRLELLPHEEADERALYPAVSPLLGGDDPLAA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEECCCCCCCCCHHHHHHHHHCCCCCHHHH
LSRSHQEIFRGIHRLARLFAQHRDAPSEPGIQDIQQALYGLEAVLRLHFAQEDELFNSLS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]